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2019 ACR/ARP Annual Meeting

November 8-13, 2019. Atlanta, GA.

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  • Abstract Number: 846
    MACE and VTE Across Multiple Upadacitinib Studies in Rheumatoid Arthritis: Integrated Analysis from the SELECT Phase 3 Clinical Program
  • Abstract Number: 2196
    Machine Learning Defines the Relationship Between Structural Knee Osteoarthritis and Patient-Important Outcomes: An 8-year Study of 47,858 Knee MRIs from the Osteoarthritis Initiative (OAI)
  • Abstract Number: 2915
    Machine-learning Classification Identifies a Subset of Patients That Improve on Abatacept via Modulation of a CD28-Related Pathway
  • Abstract Number: 605
    Macrophage Migration Inhibitory Factor Is a Critical Regulator in a Mouse Model of Spondyloarthritis
  • Abstract Number: 1823
    Magnetic Resonance Enterography as a Screening Tool to Detect Sacroiliitis in Crohn’s Disease: Association with Clinical and Endoscopic Markers of Crohn’s Disease Activity
  • Abstract Number: 1173
    Magnetic Resonance Imaging in Patients in Clinical Remission: Tenosynovitis and Osteitis Are Independent Predictors of Radiographic and MRI Damage Progression
  • Abstract Number: 2200
    Magnetic Resonance Imaging of Knee Joint Protection Following an Intra-Articular Injection of Lipid-Based Dexamethasone Sodium Phosphate Sustained Release Formulation on Subjects with Knee Osteoarthritis
  • Abstract Number: 2663
    Maintained Benefit in Health-Related Quality of Life of Patients with Giant Cell Arteritis Treated with Tocilizumab Plus Prednisone Tapering: Results from the Open-Label, Long-Term Extension of a Phase 3 Randomized Controlled Trial
  • Abstract Number: 831
    Maintaining Musculoskeletal Health: A Randomized Controlled Prevention Trial Amongst People at High Risk of Developing Chronic Widespread Pain
  • Abstract Number: L11
    Maintenance of Remission Following Dose De-Escalation of Abatacept in Early, MTX-Naïve, ACPA-Positive Patients with RA: Results from a Randomized Phase IIIb Study
  • Abstract Number: 1281
    Maintenance Therapy for anti-MDA5-Positive Dermatomyositis Patients with Interstitial Lung Disease: Can They Achieve Drug-Free Remission?
  • Abstract Number: 1666
    Maintenance Treatment in ANCA Associated Vasculitis in Real World Clinical Practice – Burden of Disease, Use of Glucocorticoids and Impact on Patient Functional Status Remain Major Problems
  • Abstract Number: 1998
    Major Histocompatibility Antigen HLA-DQB1*0601 Is Associated with Rheumatoid Arthritis Among Indians in a Replication Study: Evidence of Gene-Environment Interaction with LPG Stove Use
  • Abstract Number: 2753
    Major Salivary Gland Ultrasound: Pilot Study of Findings and Feasibility in Childhood-Onset Systemic Lupus Erythematosus (cSLE)
  • Abstract Number: 2269
    Major Stressors in the Year Prior to Diagnosis Affects RA Characteristics at Presentation and 1 Year
  • Abstract Number: 2584
    Management of Cutaneous Manifestations of Lupus Erythematosus: A Systematic Review
  • Abstract Number: 392
    Management of Idiopathic Inflammatory Myopathies Using Intravenous Immunoglobulin Therapy: A Retrospective Cohort Study
  • Abstract Number: 2387
    Management of Patients with Incident Rheumatoid Arthritis in Rheumatology Clinical Practice
  • Abstract Number: 1677
    Management of Severe Renal Disease in Anti-Neutrophil-Cytoplasmic-Antibodies Associated Vasculitis: Role of Rituximab and Plasma Exchange?
  • Abstract Number: 1265
    Mandibular Involvement in SAPHO Syndrome: A Single-center Retrospective Study of 26 Patients
  • Abstract Number: 1033
    Mass Cytometric Immunophenotyping Highlights a Dysregulated T cell-B Cell Axis in Patients with New-onset Lupus
  • Abstract Number: 35
    Mass Cytometry Identifies Enhanced Histone H3 Citrullination and TNFα Production by CD14 Monocytes in Subjects At-Risk for Future Development of Rheumatoid Arthritis
  • Abstract Number: 99
    Mass Cytometry Immunophenotyping of Synovial Fluid from Checkpoint Inhibitor Related Arthritis
  • Abstract Number: 461
    Maximal Improvement in Fatigue Lags Behind Achievement of Sustained Remission in Early Rheumatoid Arthritis
  • Abstract Number: 2488
    MDA Versus DAPSA: Applicability in a Real World
  • Abstract Number: 698
    Measurement of Type I IFNα Production at the mRNA Level and Its Potential Use as a Biomarker in Systemic Lupus Erythematosus
  • Abstract Number: 266
    Measuring Advanced/Extended Practice Roles in Arthritis and Musculoskeletal Care in Canada: Stand up and Be Counted Too (2)!
  • Abstract Number: 1970
    Mechanism of Chondroprotective Effects of 4-Methylumbelliferone and 2-Deoxyglucose
  • Abstract Number: 1077
    Mediation of Adverse Pregnancy Outcomes in Autoimmune Conditions by Pregnancy Complications
  • Abstract Number: 2208
    Mediators of Bone Metabolism (DKK1, OPG, Sclerostin and RANKL) in a Cohort of Patients with Elderly-onset Arthritis
  • Abstract Number: 1134
    Medicaid Spending (2013-2017) on Disease Modifying Agents Commonly Used in Rheumatoid Arthritis
  • Abstract Number: 1133
    Medicare Spending (2012-2017) on Disease Modifying Agents Commonly Used in Rheumatoid Arthritis
  • Abstract Number: 2764
    Medication Necessity and Concerns Beliefs Are Distinct, Interactive Predictors of Treatment Adherence in Rheumatoid Arthritis
  • Abstract Number: 1007
    Memory ex-Th17 Cells Contribute to Synovial Inflammation in Spondyloarthritis
  • Abstract Number: 2605
    Men and Black Persons Die at Younger Ages from Systemic Sclerosis: A Nationwide Population-based Study
  • Abstract Number: 886
    Mesenchymal Stem Cell Senescence Alleviates Their Chondrogenic and Seno-Suppressive Properties, Contributing to Osteoarthritis Development
  • Abstract Number: 857
    Mesenchymal Stem Cell Therapy Induces FLT3L and CD1c+ Dendritic Cells in Systemic Lupus Erythematosus Patients
  • Abstract Number: 2611
    Mesenchymal Stem Cells in Scleroderma: A Systematic Review
  • Abstract Number: 2543
    Meta-Analysis Examining the Clinical Significance of Monitoring of Hydroxychloroquine Levels in SLE
  • Abstract Number: 2020
    Metabolic Changes Induced by Anti-Malondialdehyde Antibodies Promote Osteoclast Development
  • Abstract Number: 1946
    Metabolic Regulation in Cybrids Obtained from Healthy and Osteoarthritic (OA) Patients: Impaired Metabolic Flexibility in OA Process
  • Abstract Number: 2918
    Metabolic Signatures of Pathogenic T Cells in Medium and Large Vessel Vasculitis
  • Abstract Number: 2324
    Metabolic Syndrome and Early Arthritis: Frequency, Association with Antibodies Profile and Disease Activity
  • Abstract Number: 227
    Metabolomic and Symptom Comparison in Women With/without Fibromyalgia: A Pilot Study
  • Abstract Number: 128
    Metabolomics Analysis Identifies Biomarkers for APS and Suggests a Potential New Pathway Related to APS Pathogenesis
  • Abstract Number: 627
    Metabolomics Screening in Axial Spondyloarthritis: Identifying Potential Biomarkers
  • Abstract Number: 2814
    Methionine Commits Immunometabolism and Epigenetic Regulation of BACH2 Loci in B Cells, Resulting in Biases Toward Plasmablast Differentiation in the Pathogenesis of SLE
  • Abstract Number: 362
    Methods to Efficiently Recruit Minority Patients with Gout for Clinic-Based Registries
  • Abstract Number: 1890
    Methotrexate Adverse Events in a Randomized Double-Blind Placebo-Controlled Trial:Results from the Cardiovascular Inflammation Reduction Trial (CIRT)
  • Abstract Number: 369
    Methotrexate and Interstitial Lung Disease in Patients with Inflammatory Articular Disease: A Systematic Review
  • Abstract Number: 2377
    Methotrexate Discontinuation and Dose Decreases After Therapy with Tocilizumab: Results from the Corrona Rheumatoid Arthritis Registry
  • Abstract Number: 1759
    Methotrexate in Patients with Hand Erosive Osteoarthritis Refractory to Usual Treatments: A Randomized, Double-blind, Placebo-controlled Trial
  • Abstract Number: 2793
    Methotrexate Intolerance: A Qualitative Descriptive Study of the Adult Rheumatoid Arthritis Patients’ Perspectives
  • Abstract Number: 926
    Methotrexate Is Associated with Reduced Cardiovascular Risk in Rheumatoid Arthritis Independent of Disease Activity Modification
  • Abstract Number: 2357
    Methotrexate Liver Toxicity in a Large Randomized Controlled Trial
  • Abstract Number: 2015
    Methotrexate Treatment Is Associated with Reduction of Neutrophil Reactive Oxygen Species and CD177 in RA Patients
  • Abstract Number: 1780
    Microbiome in Offspring of Ankylosing Spondylitis Patients
  • Abstract Number: 961
    Microenvironment in Systemic Sclerosis Provides a Protective Niche for Tissue-resident B Cells During B Cell Depletion Therapy with Anti-CD20 Antibody
  • Abstract Number: 75
    Microglia-Specific Transcriptional Signatures Correlate with Behavioral Deficits in ‘Neuropsychiatric Symptoms of Systemic Lupus Erythematosus’
  • Abstract Number: 2026
    MicroRNA-27a Can Contribute to Interferon Signatures in Systemic Lupus Erythematosus via the Suppression of Tripartite Motif-containing Protein 27
  • Abstract Number: 966
    Minimal Residual Autoimmunity After Rituximab in ANCA-associated Vasculitis Patients
  • Abstract Number: 2240
    Mining Social Media Data to Investigate Patient Perceptions Regarding DMARD Pharmacotherapy for Rheumatoid Arthritis
  • Abstract Number: 2612
    Minocycline for Refractory Calcinosis in Systemic Sclerosis: A Single-Centre Observational Cohort Study
  • Abstract Number: 1460
    Minor Salivary Gland Biopsy and Dry Ocular Tests to Detect Occult Sjögren Syndrome in Patients with Interstitial Pneumonia with Autoimmune Features
  • Abstract Number: 1909
    miR-21-5p Expression as a Marker of Treatment Response in Psoriatic Arthritis Patients
  • Abstract Number: 2727
    Mitochondrial Contribution to Juvenile Dermatomyositis Pathogenesis
  • Abstract Number: 888
    Mitochondrial DNA Impact on Joint Degeneration Process Using DMM OA and Spontaneous Aging Conplastic Mice Models
  • Abstract Number: 1961
    Mitochondrial DNA Sub-haplogroup H1 Influences the Risk of Rapidly Progressive Osteoarthritis of the Knee: Data from the Osteoarthritis Initiative
  • Abstract Number: 2036
    Mitochondrial DNA: A Potential Trigger of Cyclic GMP-AMP Synthase Activation in Systemic Lupus Erythematosus
  • Abstract Number: 119
    Mitochondrial Transplantation Suppressed Muscle Inflammation and Improved the Mitochondrial Dysfunction in C Protein-induced Myositis Model
  • Abstract Number: 1722
    Mixed Cryoglobulin Immune Complex Proteomics: Analysis by Mass Spectroscopy
  • Abstract Number: 1723
    Mixed Cryoglobulinaemia Since the Advent of New Direct-acting Antivirals for Hepatitis C Infection: Clinical Characteristics, Etiologies and Biological Features in 679 Patients
  • Abstract Number: 1108
    Mobile Apps in Rheumatology: Review and Analysis Using the Mobile App Rating Scale (MARS)
  • Abstract Number: 2286
    Mobile Responsive App – Useful Additional Tool for Data Collection in the German Pregnancy Register Rhekiss?
  • Abstract Number: 2892
    Model-based Cost-Effectiveness Analyses Comparing Combinations of Urate Lowering Therapy and Anti-Inflammatory Treatment in Newly Diagnosed Gout Patients
  • Abstract Number: 2215
    Modeling-Based Bone Formation Persists in the Femoral Neck Despite Remodeling Inhibition in Subjects Treated with Denosumab
  • Abstract Number: 729
    Modelled Patient Level Skin Score Trajectory Predicts Risk of Death or Major Organ-Based Complications in Diffuse Cutaneous Systemic Sclerosis
  • Abstract Number: 2376
    Modifiable Factors Associated with Response to Treatment in Early Rheumatoid Arthritis
  • Abstract Number: 545
    Molecular Analysis of the Mode of Action of Upadacitinib in Rheumatoid Arthritis Patients: Whole Blood RNA Expression Data from the SELECT-NEXT Study
  • Abstract Number: 1039
    Molecular Profiling Identifies Immunologic Subgroups and Informs Mechanism of Action of Baricitinib in SLE
  • Abstract Number: 16
    Monoclonal ACPA Promote Synovial Fibroblasts Migration Through a Peptidylarginine Deiminases (PAD) Dependent Pathway
  • Abstract Number: 813
    Monocyte and Macrophage Transcriptional Phenotypes in Systemic Juvenile Idiopathic Arthritis Reveal TRIM8 as a Mediator of IFNγ Hyperresponsiveness and Risk for Macrophage Activation Syndrome
  • Abstract Number: 811
    Monomethyl Fumarate as a Novel Therapy for Macrophage Activation Syndrome: Mechanism of Action in an Animal Model
  • Abstract Number: 1937
    Mononuclear Leukocyte DNA Methylome Imprinting of Networked Signaling and Immunity Regulatory Pathways in Gout
  • Abstract Number: 1238
    Monosodium Urate and Calcium Pyrophosphatecrystal-induced Interleukin 1 Production Depends on Glucose Uptake Through Glut1 Transporter
  • Abstract Number: 928
    Monotherapy with Upadacitinib in MTX-naïve Patients with Rheumatoid Arthritis: Results at 48 Weeks
  • Abstract Number: 1218
    Monthly Dosing of ImmTOR Tolerogenic Nanoparticles Combined with Pegylated Uricase (Pegadricase) Enables Sustained Reduction of Acute Gout Flares in Symptomatic Gout Patients
  • Abstract Number: 1235
    Monthly Dosing of ImmTOR Tolerogenic Nanoparticles Combined with Pegylated Uricase (Pegadricase) Mitigates Formation of Anti-Drug Antibodies Resulting in Sustained Uricase Activity in Symptomatic Gout Patients
  • Abstract Number: 727
    Mortality and Morbidity in Scleroderma Renal Crisis: A Systematic Literature Review
  • Abstract Number: 1623
    Mortality in a SLE Inception Cohort of Hispanic Patients
  • Abstract Number: 1351
    Mortality of Rheumatoid Arthritis Patients, Treated to Target at Low Disease Activity: 17-years Follow-up of the BeSt Cohort
  • Abstract Number: 2628
    Mortality Predictors in ANCA-associated Vasculitis: Experience of a Brazilian Monocentric Cohort of a Rheumatology Center
  • Abstract Number: 897
    Mortality Rates After Coronary Revascularization Procedures Among Systemic Lupus Erythematosus Compared to Diabetes Mellitus and General Population Medicaid Patients
  • Abstract Number: 842
    Mortality Ratio and Risk Factors in CT Confirmed Rheumatoid Arthritis Related Lung Disease: UIP, Pleural Effusion and the Time of Diagnosis of Rheumatoid Arthritis – Lung Disease
  • Abstract Number: 672
    Mouse SLE Studies Do Not Describe Human SLE
  • Abstract Number: 856
    MRI of the Sacroiliac Joints in Athletes: Do Semi-axial Slices Added to Standard Semi-coronal Scans Facilitate Recognition of Non-specific Bone Marrow Edema?
  • Abstract Number: 2374
    MRI of the Wrist in Early Rheumatoid Arthritis After 1-year Treat-to-target Strategy
  • Abstract Number: 2206
    MRI-based Textural Analysis of Trabecular Bone: A Novel Method for the Opportunistic Screening of Bone Quality
  • Abstract Number: 2185
    MRI-detected Abnormalities in Prediction Models of Incident Radiographic Knee Osteoarthritis over 10 Years of Follow-up
  • Abstract Number: 60
    mTORC1-phosphorylated CXCR3+memory B Cells and Their Potential as a New Mode of Action of TNF Inhibitors in RA
  • Abstract Number: 1377
    MTX Withdrawal in Patients with RA Who Achieve Low Disease Activity with Tofacitinib Modified-Release 11 Mg Once Daily + MTX: An Assessment of the Impact on the Short Form-36 Patient-Reported Outcome
  • Abstract Number: 108
    Mucosal Associated Invariant T Cells in Giant Cell Arteritis
  • Abstract Number: 2736
    Mucosal-associated Invariant T Cells Can Be Therapeutically Targeted in Lupus
  • Abstract Number: 2364
    Multi-center Analyses on 518 Cases with Rheumatoid Arthritis Developing Lymphoproliferative Disorders (RA-LPD): The Prognostic Factors and the Influence of Anti-rheumatic Drugs on LPD Development
  • Abstract Number: 1935
    Multi-Organ System Meta-Analytic Approach to Investigating Sarcoidosis
  • Abstract Number: 1479
    Multi-Symptom Impact on the EQ5D Index in Bio-naïve Active Psoriatic Arthritis Patients: An Analysis Through Week 24 of the GO-VIBRANT Study
  • Abstract Number: 2190
    Multi-vendor Multi-site T1ρ and T2 Quantification of Knee Cartilage
  • Abstract Number: 1651
    Multicenter Double-Blind, Proof-of-Concept, Randomized Placebo-Controlled Trial of Riociguat in Systemic Sclerosis-associated Digital Ulcers
  • Abstract Number: 541
    Multicenter, Evaluator-blinded, Randomized, Non-inferiority Study, to Assess the Efficacy, Safety and Immunogenicity of Etanercept Biosimilar (EtaBS) vs. Reference Etanercept (EtaRef) in Combination with Methotrexate for the Treatment of Patients with Rheumatoid Arthritis
  • Abstract Number: 442
    Multidimensional Health Assessment Questionnaire (MDHAQ) as an Effective Screening Tool to Identify Concomitant Depression in Patients with Rheumatoid Arthritis and Spondyloarthritis in Routine Care
  • Abstract Number: 441
    Multidimensional Health Assessment Questionnaire (MDHAQ) Scores in Spain vs USA: Similar Scores for Clinical Status and Self-report of Depression in Rheumatoid Arthritis (RA) but Poorer Scores for Both in Spondyloarthropathies (SpA) in Spain
  • Abstract Number: 2464
    Multidisciplinary Unit of Psoriatic Arthritis: Clinical Results
  • Abstract Number: 2166
    Multimodal Edema Management After Total Knee Arthroplasty: A Pilot Study
  • Abstract Number: 2305
    Multimorbidity May Worsen Fatigue in Patients with Rheumatoid Arthritis
  • Abstract Number: 778
    Multiple Genetic Diagnoses in a Cohort of Patients with Cryopyrin Associated Periodic Syndrome (CAPS)
  • Abstract Number: L02
    Multiple Industrial Air Pollutants and Anti-Citrullinated Protein Antibody Positivity
  • Abstract Number: 1293
    Multiple Subpopulations of Lymphocytes Were Absolutely Decreased in Dermatomyositis/polymyositis Patients and Restored by Low-dose IL-2
  • Abstract Number: 918
    Multiplex Serum Analysis Identifies Potential Biomarkers of Systemic Juvenile Idiopathic Arthritis, Macrophage Activation Syndrome, and Associated Pulmonary Alveolar Proteinosis: Evidence for Independently-regulated Hyperinflammatory and Eosinophilic Inflammation
  • Abstract Number: 2148
    Muscle Involvement Revealed by 18F-PET-CT in Polymyalgia Rheumatica
  • Abstract Number: 599
    Muscle Physical Properties in Young Adult Axial Spondyloarthritis Patients, the MyoSpA Study
  • Abstract Number: 238
    Muscle Pressure as Measured by a Manometer Correlates with Dolorimetry in Patients with Fibromyalgia
  • Abstract Number: 235
    Muscle Pressure Correlates with Pain Levels in Fibromyalgia Patients and Muscle Tension May Be the Cause of Their Pain
  • Abstract Number: 2144
    Musculoskeletal Immune-Related Adverse Events After Immune Checkpoint Inhibitor Therapy: Single Center Experience
  • Abstract Number: 907
    Musculoskeletal Sarcoidosis: Characterization and Clinical Expression of 129 Patients with Granulomatous Infiltration of Bones And/or Muscles
  • Abstract Number: 2147
    Musculoskeletal Ultrasound Enhances the Evaluation of Checkpoint Inhibitor Associated Musculoskeletal Immune Related Adverse Events
  • Abstract Number: 1649
    Mycophenolate Mofetil and Cyclophosphamide Improve Health-Related Quality of Life in Patients with Systemic Sclerosis Who Participated in SLS II
  • Abstract Number: 794
    Mycophenolate Mofetil for the Treatment of Severe or Methotrexate-refractory Juvenile Localized Scleroderma
  • Abstract Number: 1771
    MyD88 S209R Enhances Inflammation in Mouse Models of Arthritis
  • Abstract Number: 1869
    Myeloid Dendritic Cells (mDCs) Are Major Producers of Interferon-β in Dermatomyositis and Higher Numbers of mDCs Are Found in Hydroxychloroquine Nonresponders
  • Abstract Number: 1045
    Myocardial Involvement in SSc: Key Role of Lin-gp38+ Stromal Cells in the Onset of Fibrosis and Defects of the Conduction System
  • Abstract Number: 475
    Myopenia in Elderly Female Patients with Rheumatoid Arthritis Is Associated with Severe Joint Damage: A Cross-sectional Study
  • Abstract Number: 2160
    Myopenia Is an Independent Risk Factor for Rotator Cuff Tear and Shoulder Dysfunction in Elderly People : Data from NAMGARAM Cohort
  • Abstract Number: 1769
    Myosin Regulation of TNF Receptor 2 Signaling May Contribute to Anti-TNF Therapy Response
  • Abstract Number: 406
    Myositis Related Antibodies and Interstitial Lung Disease: Variables Associated with Baseline Lung Function and Functional Improvement: Results from a Multicentric Latin-american Cohort
  • Abstract Number: 1276
    Myositis Specific Antibodies and Clinical Features in Patients from Argentina
  • Abstract Number: 2588
    Myositis-specific and -associated Antibodies in Systemic Sclerosis: Prevalence and Clinical Associations
  • Abstract Number: 1871
    Myositis-Specific Antibodies and Muscle Histopathology in Juvenile Dermatomyositis: New Insights into the Mechanism of Injury
  • Abstract Number: 664
    Myxovirus Resistance Protein a Is a Useful Additional Histological Marker for Cutaneous Lupus Erythematosus
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