2017 ACR/ARHP Annual Meeting Archives

Abstract Number: 556

Identification and Validation of S100 Salivary Proteins As Putative Biomarkers for Different Subsets of Primary Sjögren’s Syndrome Patients
Abstract Number: 180

Identification of a Functional Susceptible Variant in Distal Enhancer of Mir-146a By CRISPR-Cas9
Abstract Number: 1668

Identification of a Serum Measure of Lupus Nephritis Activity That Detects Molecular Pathways and Mechanisms Implicated in Renal Damage
Abstract Number: 1722

Identification of a Sub-Population of Autoantibodies Targeting BICD2 Cross-Reacting with CENP-a Derived Peptides in Patients with Systemic Sclerosis
Abstract Number: 758

Identification of Biomarkers Predictive of Pulmonary Arterial Hypertension in Systemic Sclerosis
Abstract Number: 1010

Identification of Circulating Biomarkers of Disease Activity and Organ Involvement in ANCA-Associated Vasculitis By Targeted Proteomics
Abstract Number: 2602

Identification of Clinical and Serological Predictive Factors of Response to Rituximab Treatment in Systemic LUPUS Erythematosus (SLE) Patients
Abstract Number: 858

Identification of Clinically Relevant Pain Profiles in Individuals with Active RA
Abstract Number: 181

Identification of Disease-Susceptible Lncrna Contributed to Abnormal Activation of Type I Interferon Pathway in Systemic Lupus Erythematosus
Abstract Number: 674

Identification of IRAK4-Dependent Gene Signature As a Biomarker Candidate for IRAK4 Small-Molecule Inhibitor in Systemic Lupus Erythematosus
Abstract Number: 1334

Identification of Key Regulators for Resolution of Chronic Inflammatory Arthritis through a Systems Approach
Abstract Number: 984

Identification of Key Screening Characteristics for Systemic Lupus Erythematosus Natural History
Abstract Number: 1659

Identification of Long Noncoding RNA RP11-2B6.2 As a Positive Regulator through Type I Interferon Pathway in Lupus Nephritis
Abstract Number: 2125

Identification of Long-Term Prognostic Factors for Relapse or Exacerbation in Patients with Pulmonary Sarcoidosis: A Single Center Long-Term Observational Cohort Study
Abstract Number: 2134

Identification of Multiple Cancer Associated Myositis Specific Antibodies in Idiopathic Inflammatory Myopathies: A Large Longitudinal Cohort Study
Abstract Number: 950

Identification of Naturally Processed Immunodominant Topoisomerase I Epitopes in Patients with Systemic Sclerosis
Abstract Number: 168

Identification of Novel Susceptibility Loci in a Large UK Cohort of Juvenile Idiopathic Arthritis (JIA) Cases
Abstract Number: 2270

Identification of Optimal Subcutaneous Doses of Tocilizumab in Children with Polyarticular-Course Juvenile Idiopathic Arthritis
Abstract Number: 2976

Identification of Systemic Lupus Erythematosus Causal Risk Variant Candidates Spanning the UBE2L3 Haplotype
Abstract Number: 2057

Identification of Urate Deposits in Patients with Asymptomatic Hyperuricemia Using a Dual-Energy CT Scan
Abstract Number: 2

Identifying “Second Hit” Risk Factor(s) Associated with Thrombosis and Pregnancy Morbidity in Ethnically Diverse Antiphospholipid Antibodies Positive Patients
Abstract Number: 983

Identifying Exposures to Chemicals in Patients with SLE – a Non-Targeted Exposome Approach Reveals Enrichment for Phthalates
Abstract Number: 1871

Identifying Pain Sites Highly Associated with the Fibromyalgia (FM) Phenotype
Abstract Number: 859

Identifying Pain Susceptibility Phenotypes in Those Free of Knee Pain with or at Risk for Knee Osteoarthritis and Their Relation to Developing Knee Pain
Abstract Number: 2946

Identifying Rapid Structural Disease Progression in Knee Osteoarthritis
Abstract Number: 1854

Identifying Vulnerable Patient Populations Based on Age and Physical Function on Clinical Outcomes Following Total Knee Arthroplasty
Abstract Number: 1857

If Mobile Advertising Is the Future, the Future Is Now: Productivity of Digital Ads By Terminology and Delivery Device.
Abstract Number: 2882

IgG Galactosylation Status Combined with MYOM2 SNP Precisely Predicts Anti-TNF Response in Ankylosing Spondylitis
Abstract Number: 74

IL-17 Blockade Attenuates Osteoblastic Activity and Differentiation in Ankylosing Spondylitis
Abstract Number: 659

IL-17 Producing T Cells and Its Dichotomy: A Mixed Response of the Innate and Acquired Immune System in Psoriatic Arthritis
Abstract Number: 975

IL-17A Induced Autophagy That the Proliferation of Rheumatoid Arthritis Fibroblast-like Synoviocytes through Down-Regulation of PI3K/AKT/mTOR Signaling Pathway
Abstract Number: 1896

IL-18 As a Diagnostic Biomarker, Differentiating Systemic JIA from Acute Leukaemia, Severe Bacterial Infections and Other Auto-Immune Disorders
Abstract Number: 2698

IL-21-mTOR Axis Blocks the Differentiation and Function of SLE Tregs Via Suppression of Autophagy
Abstract Number: 1576

IL-23 Promotes Fecal Microbiota Dysbiosis Associated with Susceptibility to Spondyloarthritis and Ileitis in ZAP-70 Mutant SKG Mice
Abstract Number: 34

IL-23 Regulates Development of Spontaneous Germinal Centers and Pathogenic Autoantibody Production in BXD2 Mice
Abstract Number: 78

IL-37 Is Associated with Increased Atherogenesis in Patients with Rheumatoid Arthritis
Abstract Number: 973

IL-6 and TNF-a Cooperate to Modulate the Cell Cycle of RA-Fibroblast-like Synoviocytes Via Cyclin Dependent Kinase Inhibitors
Abstract Number: 1730

IL-6 Mediates Activation of Macrophages in Patients with Systemic Sclerosis
Abstract Number: 1795

IL-7 in Primary Sjogren Syndrome (pSS) Is Secreted By Salivary Gland Epithelial Cells after IFN Stimulation and Is Associated with B-Cell Activation
Abstract Number: 864

IL-9-Producing Innate Lymphoid Cells – Keyplayers That Orchestrate Resolution of Chronic Inflammation in Arthritis
Abstract Number: 940

IL1RN Variation Is Associated with Systemic Juvenile Idiopathic Arthritis and Predicts Non-Response to Anakinra Treatment
Abstract Number: 2571

IL23 Deficiency Alters Thymic Selection in Lupus Prone Mice
Abstract Number: 594

Imaging Biomarkers in Crohn’s Associated Axial Spondyloarthritis
Abstract Number: 259

Imaging for Diagnosis, Monitoring and Outcome Prediction of Large Vessel Vasculitis: A Systematic Review of the Literature and Meta-Analysis Informing the EULAR Recommendations
Abstract Number: 850

Immune Checkpoint Inhibitors and Inflammatory Myopathies: Data from the US Food and Drug Administration Adverse Event Reporting System
Abstract Number: 2641

Immune Complex-Driven Neutrophil Activation in Systemic Lupus Erythematosus – Novel Biomarkers of Disease Activity and Severity
Abstract Number: 566

Immune Response to Seasonal Flu Vaccination in Patients with Primary Sjogren’s Syndrome
Abstract Number: 1325

Immune Responses to Peptides Containing Homocitrulline or Citrulline in the DR4-Transgenic Mouse Model of Rheumatoid Arthritis
Abstract Number: 2106

Immune-Related Adverse Events in Cancer Patients Treated with Immune Check Point Inhibitors: A Single Center Experience
Abstract Number: 481

Immunocompetent Cells Expressing Citrullinated Proteins in Joint Synovium of Osteoarthritis and Rheumatoid Arthritis
Abstract Number: 2415

Immunogenicity and Persistence of a Prime-Boost Re-Vaccination Strategy for Pneumococcal Vaccines (13-Valent Pneumococcal Conjugate Vaccine + 23-Valent Pneumococcal Polysaccharide Vaccine) in Patients with Rheumatoid Arthritis: A Pilot Study
Abstract Number: 383

Immunogenicity of 13 Valent Pneumococcal Vaccine in Children with Lupus: Single Center Experience in South Texas
Abstract Number: 2748

Immunogenicity of Infliximab Among Patients with Behcet’s Syndrome: A Controlled Study
Abstract Number: 1940

Immunologic Synovitis Score: A New Score for Synovial Membrane Characterization in Inflammatory and Non-Inflammatory Arthritis
Abstract Number: 2419

Immunomodulatory Effects of Bone-Marrow Mesenchymal Stem Cells in Rheumatoid Arthitis: Influence of Disease Activity
Abstract Number: 676

Immunosignature Autoantibody Profiles Provide Mechanistic Insight into Systemic Lupus Erythematosus and Differentiation from Symptomatically Overlapping Diseases
Abstract Number: 576

Immunosignature-Based Diagnosis and Prediction of Therapeutic Response Enables Retrospective Patient Stratification in a Phase IIa Clinical Trial for VAY736 in Primary Sjögren’s Syndrome
Abstract Number: 116

Immunotherapy-Induced Rheumatic Disease: How Prepared Are Rheumatologists to Address This Emerging Condition?
Abstract Number: 98

Impact of a Lung Ultrasound Course for Rheumatology Specialist (IMPACT-2)
Abstract Number: 908

Impact of a National Training Program on Primary Care Providers Utilization of Knee MRI
Abstract Number: 96

Impact of a Student Led Rheumatology Interest Group on Medical Student Interest in Rheumatology
Abstract Number: 1155

Impact of Adalimumab on Immunosuppressant Use in Patients with Active and Inactive Non-Infectious Intermediate, Posterior, or Pan-Uveitis in the Ongoing Open Label Study: Visual-III
Abstract Number: 1422

Impact of Adalimumab on Prednisone Use in Patients with Rheumatoid Arthritis in a Real World Setting – Results from the Corrona Registry
Abstract Number: 1470

Impact of Anti-Drug Antibody and Injection Site Reaction on Efficacy: 24-Week Results from a Phase III Study Comparing SB4 (etanercept biosimilar) with Reference Etanercept in Patients with Rheumatoid Arthritis
Abstract Number: 699

Impact of Anti-RBP Antibodies on Disease Activity and Quality-of-Life in Immunosuppressant Naive Systemic Lupus Erythematosus
Abstract Number: 108

Impact of Antiphospholipid Syndrome Ibook on Medical Students’ Improvement of Knowledge: An International Randomized Controlled Experimental Study
Abstract Number: 234

Impact of Arthritis Among Populations with Chronic Health Conditions in Rural Counties of the United States – 2015
Abstract Number: 1222

Impact of Bariatric Surgery on Bone Mineral Density : Observational Study of 110 Patients Followed up in a Specialised Centre for the Treatment of Obesity in France
Abstract Number: 1453

Impact of Biological and Targeted Synthetic Dmards on Work in Patients with Chronic Inflammatory Arthritides : A Meta Analysis of Randomized Controlled Trials and Controlled Cohorts
Abstract Number: 2377

Impact of Body Mass Index and Weight Loss on Incident Disability in Patients with Rheumatoid Arthritis
Abstract Number: 1162

Impact of Bone Localization on the Prognostic of Langerhans Cell Histiocytosis: A Monocentric Retrospective Study
Abstract Number: 528

Impact of Comorbidities on the Occurrence of Infections in Rheumatoid Arthritis Treated By Biologic Agents
Abstract Number: 743

Impact of Detect on Right Heart Catheterization Referral and Results; Data from a Prospective, Unselected, Systemic Sclerosis Cohort
Abstract Number: 1129

Impact of Diuretics on Urate Lowering Therapy in Patients with Gout: Analysis of an Inception Cohort
Abstract Number: 989

Impact of DMARD Treatment on Risk of Repeat Cardiovascular Events Among Patients with Rheumatoid Arthritis, Psoriatic Arthritis, or Psoriasis
Abstract Number: 1344

Impact of Fibromyalgic RA on Composite Scores; Results from a Longitudinal Study of RA Patients Initiating Bdmard Therapy
Abstract Number: 1424

Impact of Glucocorticoid Therapy on the Efficacy of SC Abatacept or Adalimumab in RA Patients with Inadequate Response to MTX: A Post Hoc Analysis of Data from a Head-to-Head Trial
Abstract Number: 2512

Impact of Inflammatory Bowel Disease in Early Spondyloarthritis in a Prospective Longitudinal Cohort
Abstract Number: 1957

Impact of Maternal Systemic Autoimmune Rheumatic Diseases on Neonatal Outcomes: A Population-Level Analysis
Abstract Number: 2246

Impact of Patient Education Tool to Increase Cardiovascular Risk Konwledge, Attitudes, and Behaviors in Patietns with Rheumatoid Arthritis
Abstract Number: 1038

Impact of Patient Support Program Utilization on Patient Activation Measure Scores Among Patients with Rheumatoid Arthritis
Abstract Number: 2677

Impact of Rheumatologic Evaluation and Serologic Testing on Patients with Fibrotic Interstitial Lung Disease: A Single Center Retrospective Experience
Abstract Number: 2540

Impact of Sleep on Measures of Disease Activity in Psoriatic Arthritis
Abstract Number: 428

Impact of Smoking Cessstion Advise in Patients with Rheumatoid Arthritis to Help Quit Smoking
Abstract Number: 1383

IMPACT of Smoking in the Expression of Periodontitis and Anticitrullinated Protein Antibodies in Rheumatoid Arthritis
Abstract Number: 1242

Impact of Social Support and Illness Perception on the Transition of Pediatric SLE Patients to Adult Care
Abstract Number: 1053

Impact of Step Therapy Protocols on North Carolina Rheumatologists’ Job Satisfaction and the Quality of Care Received By Their Patients with Rheumatoid Arthritis
Abstract Number: 133

Impact of the Five Components of the Euroqol 5-Dimensions Instrument on Healthcare and Work-Loss Costs in Rheumatoid Arthritis: Observational Data from Southern Sweden
Abstract Number: 129

Impact of the Multi-Biomarker Disease Activity Score Results on Whether Rheumatologists Changed Biologic Therapy for RA Patients
Abstract Number: 2392

Impact of the Pattern of Interstitial Lung Disease on Mortality in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
Abstract Number: 1521

Impact of Time Since Diagnosis, Age, and Number of Prior Non-Steroidal Anti-Inflammatory Drugs on 52-Week Clinical Response to Adalimumab in Patients with Ankylosing Spondylitis
Abstract Number: 1068

Impact of TNF Antagonist Treatment on the Gut Microbiome In Vivo
Abstract Number: 2966

Impact of Tofacitinib Treatment Compared with Placebo or Methotrexate on Cardiovascular Risk Scores in Six Phase 3 Randomized Controlled Trials
Abstract Number: 1980

Impact of Whole-Body Cryotherapy on Gene Expression of Peripheral Blood Cells in Patients with Fibromyalgia and Association with Patient-Reported Outcomes
Abstract Number: 1265

Impaired Cardiac Function in Juvenile Mixed Connective Tissue Disease Compared with Controls
Abstract Number: 1911

Impaired Control of Autoreactive T Cell Expansion Is Coupled with Type-1 Regulatory T Cell Deficiency in BALB/c ZAP70W163C Mutant Mice
Abstract Number: 200

Implementation and Evaluation of a Novel Nurse-Led Telemedicine Intervention for Dose Escalation of Urate-Lowering Therapy in Gout: A Clinical Practice Improvement Project
Abstract Number: 430

Implementation of a Treat-to-Target Remission Strategy for Rheumatoid Arthritis in Australian Public and Private Rheumatology Clinics – Identification of Clinician and Patient Barriers
Abstract Number: 1338

Important Role of CD11c+ Dendtritic Cells in Inflammatory Arthritis
Abstract Number: 187

Improved Identification of Pseudogout in Electronic Medical Records By Adding Text String Searching to a Billing Code Algorithm
Abstract Number: 508

Improved Patient-Reported Outcomes in Patients with Rheumatoid Arthritis Who Failed Adalimumab or Placebo Treatment and Were Rescued with Baricitinib
Abstract Number: 595

Improved Patient-Reported Outcomes in Psoriatic Arthritis Patients Treated with Abatacept: Results from a Phase III Trial
Abstract Number: 2029

Improved Provider Awareness and Delivery of Zoster Vaccination in Patients with Rheumatoid Arthritis Contemplating Biologic Therapy: Need to Target Eligible Patients Prescribed for Vaccination Post-Clinic
Abstract Number: 2921

Improved Survival Following Renal Transplantation in Waitlisted Patients with Systemic Lupus Erythematosus in the United States
Abstract Number: 1789

Improved Survival with Transplantation in Granulomatosis with Polyangiitis in the United States: Data from the US Renal Data System
Abstract Number: 417

Improvement in Overall Work Productivity Among Biologic-NaïVe Patients with Rheumatoid Arthritis Treated with Tocilizumab Subcutaneous Injection: A Prospective, Real World, Observational Study in Japan
Abstract Number: 376

Improvement of Disease Activity in Patients with Colchicine-Resistant FMF, Hids/Mkd and TRAPS Assessed By Autoinflammatory Disease Activity Index (AIDAI): Results from a Randomized Phase III Trial
Abstract Number: 633

Improvement of Joint Inflammation As Assessed By MRI and Power Doppler Ultrasound (PDUS) in an Open Label Study in Patients with Active Psoriatic Arthritis Treated with Secukinumab.
Abstract Number: 1515

Improvements in Enthesitis Scores with Certolizumab Pegol Treatment in Males and Females with Active Axial Spondyloarthritis Are Maintained to Week 204
Abstract Number: 2480

Improvements in Remission and Low Disease Activity Are Achieved with Ongoing Sarilumab Treatment, in Patients with Rheumatoid Arthritis in 2 Phase 3 Studies
Abstract Number: 1530

Improvements in Sleep Problems and Pain in Patients with Active Ankylosing Spondylitis Treated with Intravenous Golimumab: 28-Week Results of the Phase III Trial
Abstract Number: 602

Improvements in Work Productivity with up to 104 Weeks of Apremilast Monotherapy: Results from a Phase 3b, Randomized, Controlled Study in Biologic-NaïVe Subjects with Active Psoriatic Arthritis
Abstract Number: 2848

Improving Gout Outcomes: The Randomized Evaluation of an Ambulatory Care Pharmacist-Led Intervention to Optimize Urate Lowering Pathways (RAmP-Up) Study
Abstract Number: 100

Improving Internal Medicine Resident’s Knowledge through a Web-Based Musculoskeletal Educational Module
Abstract Number: 458

Improving Knowledge of Rheumatoid Arthritis Clinical Trial Results Among Rheumatologists: Effect of an Online Educational Intervention
Abstract Number: 2994

Improving Outcomes Using a Treat to Target Approach and Clinical Decision Support in Polyarticular Juvenile Idiopathic Arthritis
Abstract Number: 1081

Improving Patient-Reported Outcomes Collection and Documentation for Patients with Rheumatoid Arthritis at Multilingual, Safety Net Hospital Rheumatology Clinic
Abstract Number: 2040

Improving Quality of Care for Rheumatoid Arthritis Patients in an Underserved Area
Abstract Number: 1676

Improving Sensitivity to Change of the Modified Rodnan Skin Score over Time
Abstract Number: 1989

Improving Sleep in Fibromyalgia Patients Ameliorates Their Pain
Abstract Number: 721

Improving the Quality of Care in Systemic Lupus Erythematosis (SLE) through Time-Structured, Information Technology-Enhanced, Quality Improvement Indicator-Driven Patient Management
Abstract Number: 1851

Improving Walking Ability in Degenerative Lumbar Spinal Stenosis: A Randomized Trial Comparing 2 Self-Management Training Programs
Abstract Number: 2506

In Ankylosing Spondylitis/Axial Spondyloarthritis Smoking Is Associated with a Dose Related Elevation in CRP, Worse Disease Activity and Worse Quality of Life over One Year
Abstract Number: 2686

In Established Pulmonary Arterial Hypertension the Follow-up Cardiac Catheterization-Derived Pulmonary Artery Systolic Pressure and Vascular Resistence May be Predicted By Echocardiography- a Longitudinal Study in Two Connective Tissue Disease Cohorts
Abstract Number: 1402

In RA, Becoming Seronegative over the 1st Year of DMARD Treatment Does Not Improve Chances of Drug-Free Remission in the Long-Term
Abstract Number: 2452

In Real-World Clinical Practice, Patients Switching from IV to SC Abatacept Maintain Clinical Efficacy after Switch
Abstract Number: 2400

In Rheumatoid Arthritis: Vitamin-D Deficiency Is an Outcome and a Cause of Subclinical Renal Impairment
Abstract Number: 966

In Search of Mechanisms Underlying Fibroblast-like Synoviocyte Cell-to-Cell Cargo Transfer
Abstract Number: 955

In Vitro Effects of CR6086, a Potent ProstaglandinE2 Subtype 4 Receptor Antagonist, on Bone Erosive Pathways
Abstract Number: 52

In Vivo Effect of Opticin Deficiency in a Surgically Induced Mouse Model of Osteoarthritis
Abstract Number: 1573

In Vivo Phosphorylation of p38 in Monocytes Is Enhanced in Patients with Axial Spondyloarthritis (axSpA) at the Time of Diagnosis
Abstract Number: 1387

In-Depth Temperature of Small and Large Joints Assessed By Microwave Radiometry As an Additional Biomarker in Rheumatoid Arthritis
Abstract Number: 2411

In-Hospital Risk of Asthma in Patients with Rheumatoid Arthritis: A Cross-Sectional Nationwide Analysis
Abstract Number: 1478

Inadequate Clinical Response to Sirukumab, an Anti-IL-6 Monoclonal Antibody, Can be Predicted after a Single Dose of Treatment in Patients with Rheumatoid Arthritis
Abstract Number: 997

Incidence and Clinical Characteristics of Active Tuberculosis in a Cohort of Patients with Inflammatory Arthritis Treated with TNF-Inhibitors
Abstract Number: 1625

Incidence and Outcomes of Venous Thromboembolism in Hospitalized Patients with Systemic Lupus Erythematosus: Results from Nationwide Inpatient Sample Database 2003-2011
Abstract Number: 2384

Incidence and Predictors of Dyspnea on Exertion in a Prospective Cohort of Patients with Rheumatoid Arthritis
Abstract Number: 1777

Incidence and Prevalence of Granulomatosis with Polyangiitis and Microscopic Polyangiitis in a Health Management Organization: A 15-Year Study
Abstract Number: 723

Incidence and Variability of Cardiovascular Risk Factors in Female Lupus Patients: A 3-Year Follow-up
Abstract Number: 815

Incidence in Large Vessel GCA in Northern Italy during a 11-Year Period
Abstract Number: 1483

Incidence of Cancer in a Cohort of Patients with Primary Sjögren Syndrome
Abstract Number: 2459

Incidence of Disease Worsening in Inflammatory Arthritis Patients on Long-Term Infliximab (Remicade®) Therapy
Abstract Number: 2520

Incidence of Extra-Articular Manifestations in Psa and As Patients Treated with Golimumab in Canadian Real-World
Abstract Number: 813

Incidence of Herpes Zoster in Patients with Polymyalgia Rheumatica: A Population-Based Cohort Study
Abstract Number: 142

Incidence of Hip Fracture in Rheumatoid Arthritis: British Columbia, Canada
Abstract Number: 2391

Incidence of Infections in Early Arthritis
Abstract Number: 545

Incidence of Infusion Reactions to Intravenous Golimumab: Results from a Prospective, Real-World Community Registry
Abstract Number: 1364

Incidence of Rheumatoid Arthritis in a Cohort of First Degree Relatives from the Studies of the Etiology of Rheumatoid Arthritis
Abstract Number: 16L

Incidence of Thromboembolic Events in the Tofacitinib Rheumatoid Arthritis, Psoriasis, Psoriatic Arthritis and Ulcerative Colitis Development Programs
Abstract Number: 1429

Incidence Rates of Adverse Events with Death As an Outcome during Abatacept Treatment in RA: Results from an Integrated Data Analysis from 16 Clinical Trials
Abstract Number: 1769

Incidence, Predictors, and Outcome of Diffuse Alveolar Hemorrhage in Patients with MPO-ANCA Positive Microscopic Polyangiitis: A Multi-Center Retrospective Cohort Study
Abstract Number: 2945

Incident Hand OA Is Strongly Associated with Reduced Peripheral Blood Leukocyte Telomere Length
Abstract Number: 102

Incorporating Temporal Artery Ultrasound in a UK District General Hospital with No Prior Colour Doppler Sonography Service: An Encouraging Preliminary Analysis
Abstract Number: 1583

Increase in Arginase Activity and Related Arginine Metabolites in Patients with Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA): Potential Mechanisms for Endothelial Dysfunction
Abstract Number: 993

Increase in Prevalence of Psoriasis Arthritis over Time: Analysis of Claims Data from 65 Million People in Germany from 2009 to 2012
Abstract Number: 1611

Increased Body Mass Index May Not be a Risk Factor for the Development of Lupus Nephritis
Abstract Number: 2406

Increased Cartilage Damage in Metacarpophalangeal Joints of ACPA Positive Rheumatoid Arthritis (RA) Patients Using T2 Mapping in 3 Tesla Magnetresonance Imaging (MRI)
Abstract Number: 1846

Increased CD38hiCD27+ Plasmablast Frequency in Remission Predicts Relapsing Disease in Granulomatosis with Polyangiitis Patients
Abstract Number: 2691

Increased Circulating Cadherin-11 Levels in Patients with Systemic Sclerosis
Abstract Number: 2448

Increased Cumulative Exposure to Tumor Necrosis Factor Inhibitors Reduces Radiographic Progression in US Veterans with Rheumatoid Arthritis in Real World Clinical Practice
Abstract Number: 1733

Increased Differentiation Resistance of Regulatory T Cells to Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus Patients
Abstract Number: 903

Increased Expression of CCN4/WISP1 in Osteoarthritic Articular Cartilage Is Epigenetically Regulated and Disrupts Cartilage Homeostasis
Abstract Number: 2915

Increased Expression of Malondialdehyde-Acetaldehyde Adducts (MAA) and Anti-Maa Antibody in Rheumatoid Arthritis-Interstitial Lung Disease
Abstract Number: 761

Increased Expression of the TNF Superfamily Member LIGHT/TNFSF14 and Its Receptor (TNFRSF14) in Patients with Systemic Sclerosis
Abstract Number: 488

Increased Expression of TNF-α and PAD-2 in Human Monocytes Following Treatment with Protein Modified with Malondialdehyde-Acetaldehyde (MAA) and Citrulline
Abstract Number: 18

Increased Frequency of Nailfold Videocapillaroscopy Abnormalities in Primaryantiphospolipid (PAPS) Patients
Abstract Number: 1160

Increased Incidence of Upper and Lower Gastrointestinal Events in Patients with Sarcoidosis: A Population-Based Cohort Study
Abstract Number: 1667

Increased Levels of BAFF in SLE Patients Correlates with Neutrophil Activation and Autoantibody Production
Abstract Number: 766

Increased Plasma Levels of Hsp90 Are Associated with More Severe Organ Involvement in Patients with Systemic Sclerosis
Abstract Number: 2527

Increased Prevalence of Subclinical Atherosclerosis in Moderate-Severe Plaque Psoriasis Patients
Abstract Number: 1766

Increased Renal Damage in Hypocomplementemic Patients with ANCA- Associated Vasculitis
Abstract Number: 2310

Increased Risk of Extreme Obesity in Adults with History of Childhood Arthritis
Abstract Number: 1729

Increased Serum Levels of Micro-RNA 30d and Micro-RNA 423-5p in 2 Independent Cohorts of Patients with Morphea
Abstract Number: 1071

Increased Susceptibility of SLE-Prone Mice to Pulmonary Haemophilus Influenzae Infection Was Attributed to Dysfunctions of Innate Immune Responses
Abstract Number: 2644

Increased Toll-like Receptor 7 Expression Promotes B Cell Abnormalities and Skewing of Cytokine and Autoantibody Profiles in SLE Patients
Abstract Number: 549

Increases in Lipid Levels Following Sirukumab Treatment Are Associated with Suppression of Inflammation in Rheumatoid Arthritis: Results from Two Phase 3 Trials
Abstract Number: 1095

Increasing Lipid Panel Monitoring in a Rheumatology Clinic
Abstract Number: 994

Increasing Population Burden of Psoriatic Disease in Ontario, Canada – a Longitudinal Cohort Study
Abstract Number: 199

Incremental Direct Medical Costs of Systemic Lupus Erythematosus Patients in the Years Preceding Diagnosis and the Impact of Sex: A General Population-Based Study
Abstract Number: 1293

Indications for Cesarean Delivery in Systemic Lupus Erythematosus Pregnancies
Abstract Number: 1641

Indications for Initial Renal Biopsy in Systemic Lupus Erythematosus: A Systematic Review of the Literature
Abstract Number: 2289

Individualized Prediction of Early Remission on Medication in Juvenile Idiopathic Arthritis
Abstract Number: 2638

Inducible cAMP Early Repressor Promotes Glycolysis By Inhibiting the Pyruvate Dehydrogenase Phosphatase Catalytic Subunit 2 in Th17 Cells
Abstract Number: 388

Induction of Anti-Citrullinated Protein Antibodies By Peptidyl Arginine Deiminase Immunization: A New Model for the Development of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis
Abstract Number: 1462

Induction of Immune Tolerance through an Epitope-Specific Vaccine Induces Clinical Amelioration in Patients with Rheumatoid Arthritis
Abstract Number: 2603

Induction of Lupus Nephritisin in Real Situation: Cyclophosphamide or Mycophenolate Mofetil?
Abstract Number: 1542

Inequity in Biologic DMARD Prescription for Spa across the Globe: Results from the Multi-Centre, Cross-Sectional, ASAS Comospa Study
Abstract Number: 2841

Infection Is the Major Trigger of Adult Hemophagocytic Syndrome, an Orphan Systemic Hyperinflammatory, Life-Threatening Disease: Analysis in 147 Patients (GEAS-SEMI Registry)
Abstract Number: 2140

Infections and Medications Associated with Onset of Myositis in Myovision, a National Myositis Patient Registry
Abstract Number: 2738

Infectious Complications in Systemic Necrotizing Vasculitides: Pooled Analysis of Five Prospective, Randomized, Controlled Trials
Abstract Number: 591

Inflammation on MRI of Spine and Sacroiliac Joints Is Highly Predictive of Structural Damage in Axial Spondyloarthritis: The 5 Years Data of the DESIR Cohort
Abstract Number: 2902

Inflammatory Arthritis Due to Immune Checkpoint Inhibitors: A Persistent Problem Requiring Immunosuppression
Abstract Number: 1223

Inflammatory Bowel Diseases and the Risks of Fracture and Low Mineral Density: Review of the Literature and Meta-Analysis of Observational Cohorts
Abstract Number: 1863

Inflammatory Dietary Pattern and Risk of Developing Rheumatoid Arthritis in Women
Abstract Number: 588

Inflammatory Lesions of the Sacroiliac Joints, but Not of the Spine, Are of High Utility for Recent Onset Axial Spondyloarthritis Recognition
Abstract Number: 2354

Inflammatory Markers in Relation to Risk Factors for Cardiovascular Disease in the Pre-Symptomatic Phase of Rheumatoid Arthritis
Abstract Number: 2296

Infliximab Use in JIA and Uveitis: Does Methotrexate Help or Hinder?
Abstract Number: 1935

Influence of Adipokines on the Differentiation of Spongiosa-Derived Mesenchymal Stromal Cells from Osteoporosis and Osteoarthritis Patients
Abstract Number: 2525

Influence of Cardiovascular Comorbidity on Achieving Therapeutic Goals: A Comparative Study between Recent-Onset Psoriatic Arthritis and Established Disease
Abstract Number: 208

Influence of Depression on Healthcare Expenditures Among Adults with Spondylosis, Intervertebral Disc Disorders and Other Back Problems in the United States
Abstract Number: 1450

Influence of Immunogenicity to the First Anti-TNF Therapy on Response to the Second Biologic Agent in RA Patients
Abstract Number: 2249

Influence of Large-Joint Involvement on Patient-Physician Discordance in Global Assessment of Rheumatoid Arthritis Disease Activity Analyzed By Novel Joint Index
Abstract Number: 1315

Influence of Rheumatoid Arthritis and Axial Spondyloarthritis on Pregnancy Complications, Pregnancy Outcome and Delivery Mode
Abstract Number: 1039

Influences for Therapeutic Changes in Rheumatoid Arthritis Patients from the Veterans Affairs Rheumatology Arthritis Registry Who Have Moderate to High Disease Activity
Abstract Number: 1705

Inhibition of EZH2 Stops Fibrosis and Improves Angiogenesis in Scleroderma
Abstract Number: 956

Inhibition of Fucosylation in Endothelial Cells Reduces Rheumatoid Arthritis Angiogenesis
Abstract Number: 1714

Inhibition of Hedgehog Acyltransferase Alleviates the Profibrotic Effects of Transforming Growth Factor β in Systemic Sclerosis
Abstract Number: 2564

Inhibition of Neutrophil Elastase Protects Against Glomerulonephritis and Thrombosis in a Mouse Model of Lupus
Abstract Number: 2970

Inhibition of Radiographic Progression in Psoriatic Arthritis By Adalimumab Independent of the Control of Clinical Disease Activity
Abstract Number: 2562

Inhibition of Spleen Tyrosine Kinase Improves Renal Pathology and Reduces Lymphocyte Activation in the MRL/Lpr and NZB/NZW Murine Models of Systemic Lupus Erythematosus
Abstract Number: 1321

Inhibition of the Mechanistic Target of Rapamycin Pathway and Glutaminolysis Facilitates the Expansion of Myeloid-Derived Suppressor Cells and Synergistically Ameliorates Arthritis in SKG Mice
Abstract Number: 1078

Initial Combination Therapy Versus Step-up Therapy Is More Effective and Less Costly As a Treat to Target Strategy for RA: A Markov Model Based upon the Dutch Rheumatoid Arthritis Monitoring Registry Cohorts
Abstract Number: 1188

Initial Estimates of Efficacy of Intra-Articular 2.5% Polyacrylamide Hydrogel for the Treatment of Knee Osteoarthritis: An Observational Proof-of-Concept Study
Abstract Number: 2091

Initial Phase 2 Clinical Data of SEL-212 in Symptomatic Gout Patients: Monthly Dosing of a Pegylated Uricase (Pegsiticase) with Svp-Rapamycin Enables Sustained Reduction of Serum Uric Acid Levels By Mitigating Formation of Anti-Drug Antibodies
Abstract Number: 1141

Initial Results of a Clinical Study to Determine Whether a Tolerizing Regimen of Pegloticase Can Increase the Frequency of Subjects Having Sustained Lowering of Serum Urate
Abstract Number: 2252

Initial Validation of Patient-Reported Outcomes Measurement Information System (PROMIS®) in Children with Juvenile Myositis
Abstract Number: 1144

Initiating Colchicine and Urate-Lowering Therapy Reduces Baseline Inflammation, and Improves Vascular Endothelial but Not Smooth Muscle Function in Gout Subjects: Resistance to Endothelial Improvement Among Patients with Cardiovascular Comorbidities
Abstract Number: 468

Initiation of Biologic Disease Modifying Antirheumatic Drug Therapy and Associated Changes in Disease Activity Measures in Routine Clinical Practice: Findings from a Large Contemporaneous Real World Cohort
Abstract Number: 862

iNKT Mediated Immunoregulatory Feedback Control Development of Autoimmune Arthritis in Mice
Abstract Number: 655

Innate Lymphoid Cells – New Players in Psoriatic Arthritis
Abstract Number: 1797

Insights from Treating to Target in Rheumatoid Arthritis at an Academic Medical Center
Abstract Number: 1725

Insulin-like Growth Factor Binding Protein-4 Exerts Anti-Fibrotic Effects and Its Levels Are Reduced in SSc-Associated Lung Fibrosis
Abstract Number: 619

Integrated Efficacy Analysis of Tofacitinib, an Oral Janus Kinase Inhibitor, in Patients with Active Psoriatic Arthritis
Abstract Number: 628

Integrated Efficacy Results from Two Phase 3 Trials of Ixekizumab for the Treatment of Psoriatic Arthritis
Abstract Number: 2806

Integrated Longitudinal Analysis Increases Precision and Reduces Bias: A Comparative 5-Year Analysis in the DESIR Cohort
Abstract Number: 2472

Integrated Phase 3 Safety Results of Sirukumab, an Anti–IL-6 Cytokine Monoclonal Antibody, in Patients with Active Rheumatoid Arthritis
Abstract Number: 616

Integrated Safety Summary of Tofacitinib in Psoriatic Arthritis Clinical Studies
Abstract Number: 770

Integrating Analysis of Skin RNA in Situ Hybridization Using Rnascope and Whole Skin Gene Expression in Systemic Sclerosis Skin to Localize Key Pathogenic Drivers of Skin Fibrosis
Abstract Number: 351

Integration of Electronically Captured Patient-Reported Outcomes in a Pediatric Rheumatology Clinic Visit
Abstract Number: 166

Integrative Systems Biology Approach Identifies Key Transcription Factors and Novel Rheumatoid Arthritis (RA) and Individualized Therapeutic Targets
Abstract Number: 203

Intensive Care Unit Admissions Among Patients with Rheumatic Diseases at a Tertiary Care Center
Abstract Number: 2552

Inter-Connections between Fatigue, Pain and Patient Global Assessement in Patients with Active Spondyloarthritis Followed in the Daily Clinic
Abstract Number: 1913

Inter-Omic Analysis Reveals Functional Relationship between Diverse Gut Microbiota and Dysregulated Host Immune Response in HLA-B27-Mediated Experimental Spondyloarthritis
Abstract Number: 1463

Interaction between Methotrexate and BAFF for Preventing Immunization Against TNF-α Inhibitors By Increasing Adenosine and Regulatory B-Cell Subsets
Abstract Number: 1655

Interferon b Blockade Rescues Human BM-MSC Osteoblastogenesis Defects in Systemic Lupus Erythematosus
Abstract Number: 1728

Interferon Gamma (IFN-γ) Subpopulations in Skin Homing T Cells of Localized Scleroderma
Abstract Number: 1369

Interferon Gamma Signature Genes and CXCL10 As New Biomarkers in Early Stage of Rheumatoid Arthritis
Abstract Number: 2927

Interferon Regulatory Factor (IRF) 7 in Type I IFN Signaling Represents As a Key Upstream Regulator in Early Diffuse SSc Patients and Plays Critical Role in Pathogenesis of Fibrosis
Abstract Number: 1658

Interferon Related Soluble Mediator Concentrations Significantly Correlate with Disease Activity in SLE Patients with Active Interferon Pathways
Abstract Number: 754

Interferon Siganture in Systemic Sclerosis Lung Microvascular Endothelial Cells
Abstract Number: 2349

Interferon Signature in Childhood Rheumatic Diseases
Abstract Number: 831

Interferon-Alpha Disrupts Tolerance in a Mouse Model of B Cell Anergy
Abstract Number: 866

Interferon-Alpha Overexpression Triggers an Expansion of Highly Suppressive Regulatory T Lymphocytes Protecting Against Experimental Arthritis
Abstract Number: 2813

Interferon-Induced APOL1 over-Expression Causes Autophagic Dysfunction and Mitochondrial Stress in Risk Variant-Carrying Endothelial Cells
Abstract Number: 2814

Interferon-β Production By B Cells Promotes B Cell Survival and Is Strongly Associated with Active Disease in African Americans with SLE
Abstract Number: 1930

Interleukin 1β Decreases Capacity for Repair Human Cartilage Lesions By Mesenchymal Stromal Cells on Collagen/Proteoglycan Scaffolds
Abstract Number: 367

Interleukin-1 Receptor Antagonist Is a Potential Treatment for Undifferentiated Autoinflammatory Syndromes
Abstract Number: 1793

Interleukin-17 Is Not a Determinant for the Pro- or Anti-Inflammatory Character of Interleukin-22 in Experimental Arthritis
Abstract Number: 2574

Interleukin-33 Ameliorates Murine Lupus Via Induction of Regulatory T Cells and M2 Macrophage Polarisation
Abstract Number: 1152

Interleukin-37 As an Independent Disease Activity Marker of Adult-Onset Still’s Disease
Abstract Number: 634

International League of Associations for Rheumatology. Systematic Review of the Literature to Inform Treatment Recommendations for Psoriatic Arthritis in Resource-Poor Countries
Abstract Number: 1756

Interstitial Lung Disease in ANCA Associated Vasculitis: A Distinct or an Incomplete Subset in ANCA Vasculitis Patients?
Abstract Number: 1486

Interstitial Lung Disease in Primary Sjögren’s Syndrome : Clinical Presentation, Serological Biomarkers and Long Term Outcome
Abstract Number: 2114

Interstitial Pneumonia with Autoimmune Features (IPAF): Are There Definable Subsets?
Abstract Number: 1198

Intra-Articular Hyaluronic Acid Delay to Total Knee Arthroplasty By Number of Injection Courses Received: Analysis of an Administrative Database
Abstract Number: 599

Intravenous Golimumab in Adult Patients with Active Psoriatic Arthritis: Efficacy and Safety through Week 24
Abstract Number: 2166

Intravenous Immunoglobulins in Idiopathic Inflammatory Myopathies: Efficacy and Predictive Factors for Clinical Response
Abstract Number: 177

Intronic Variants of the B-Cell Proliferator RASGRP3 Affect Its Expression, and Might Contribute to Lupus Risk
Abstract Number: 1066

Invention and Phenotypic Evaluation of Human IgG4-Knock-in Mice
Abstract Number: 2174

Investigating Exercise- and Crossfit-Induced Rhabdomyolysis: Data from a Community Healthcare System
Abstract Number: 1097

Investigating Opportunities for Cost Conscious Care: A Review of Physician Practice in Ordering Anti-Nuclear Antibody Testing at an Academic Community Hospital
Abstract Number: 652

Investigating the Role of Mechanical Stress in Spondyloarthritis Pathogenesis
Abstract Number: 1269

Investigating Time Trends in Incident Pediatric Lupus across Ethnic Groups in Toronto, Canada—a Large, Multiethnic Metropolitan Area
Abstract Number: 1017

Investigation of Differential Methylation As a Potential Biomarker of Methotrexate Response in Patients with Rheumatoid Arthritis
Abstract Number: 1455

Investigation of Poor Prognostic Factors Among Rheumatoid Arthritis Patients in Turkbio Registry
Abstract Number: 2211

Investigation of Self-Reported Painful Joint Count As an Outcome Measure in Hand Osteoarthritis
Abstract Number: 1138

Investigation on Allele Frequency of Rs3117583 and Rs9263726 in Patients with Hyperuricemia or Gout
Abstract Number: 2228

Involvement of Receptor Tyrosine Kinase a Signaling in Rhumatoid Arthritis Using Trka/C Knock-in Mice: A Multimodal Approach
Abstract Number: 1742

Involvement of T Helper 17 Cells in Inflammatory Arthritis Depends on the Host Intestinal Microbiota
Abstract Number: 1833

iRhom2 Deficiency Protects Fcgr2b-/- Lupus-Prone Mice from Kidney Damage By Modulating ADAM17-Dependent Shedding of TNF-α and EGFR Ligand
Abstract Number: 51

Irisin Ameliorates Infrapatellar Adiposity in Knee Osteoarthritis Pathogenesis By Orchestrating Adipokine Signaling
Abstract Number: 2511

Irritable Bowel Syndrome and Its Impact on Patient-Reported Outcomes in Axial Spondyloarthritis: Is It an Overlooked Comorbidity?
Abstract Number: 2181

Is a Decrease in MRI-Defined Inflammation Associated with a Decrease in Pain in Patients with Hand Osteoarthritis? a Two-Year Follow-up Study
Abstract Number: 2991

Is a Growing Waistline over 8 Years Associated with Incident Functional Limitation and Low Health-Related Quality of Life in Knee Osteoarthritis?
Abstract Number: 1356

Is ACPA-Positive RA Still a More Severe Disease Than ACPA-Negative RA? a Longitudinal Cohort Study in RA-Patients Treated from 2000 Onwards
Abstract Number: 1340

Is Depression in Patients with Rheumatoid Arthritis Associated with Disease Activity? Comparative Study between Germany and Brazil
Abstract Number: 629

Is Earlier Golimumab Treatment Initiation in Psa and As Patients Associated with Improved Outcomes?
Abstract Number: 574

Is Elastography a New Tool to Differentiate Sjögren Syndrome to Sicca Syndrome?: Results of the Elsa (elastography of salivary glands) Study
Abstract Number: 2853

Is Frailty Associated with Adverse Events after Total Joint Arthroplasty?
Abstract Number: 980

Is Intra-Articular Injection of Synvisc Associated with a Delay to Knee Arthroplasty in Knee OA Patients?
Abstract Number: 1438

Is It Necessary to Weight By Weight the Dosage of MTX in RA Patients? Results from Obsevational Analysis of Baseline Data of a Phase III Trial
Abstract Number: 1353

Is Joint Damage Due to Secondary Osteoarthritis (OA) Clinically As Important As Inflammation in Contemporary Management of Rheumatoid Arthritis (RA)?
Abstract Number: 492

Is Leukotoxin_A Produced By Aggregatibacter Actynomycetemcomitans Important for Initiating Autoimmune Responses Underlying Rheumatoid Arthritis?
Abstract Number: 158

Is Lu Eight-Brocades Exercise Beneficial for Patients with Fibromyalgia?
Abstract Number: 2990

Is Risk of Retinopathy Among Hydroxychloroquine Users of SLE Patients Accurate? a Simulation Study Accounting for Competing Risk of Death
Abstract Number: 1512

Is Sacroiliac Imaging the All-Decisive Factor in the Diagnosis of Early Axial Spondyloarthritis? Data from the Spondyloarthritis Caught Early (SPACE) Cohort
Abstract Number: 2718

Is Smoking Important in Adult IgA Vasculitis?
Abstract Number: 2938

Is Synovial Hypertrophy without Doppler Activity in Rheumatoid Arthritis Joints Sensitive to Change ? – Results of a Longitudinal Ultrasound Study
Abstract Number: 191

Is the Nature of Rheumatology Practice Changing? Damage and Distress Contribute a Greater Proportion to Decision-Making Than Inflammation in Contemporary Care
Abstract Number: 569

Is the Oral Microbiome Involved in the Pathogenesis of Sjogren’s Syndrome?
Abstract Number: 640

Is There a Relationship between Spondyloarthritis and Periodontitis? a Case-Control Study
Abstract Number: 1491

Is There a Seasonal Effect on Fatigue, Pain, and Dryness in Primary Sjögren’s Syndrome? Data from the Prospective Assess Cohort and from 3 Randomized Controlled Trials
Abstract Number: 2735

Is There an Association between Adult IgA Vasculitis and Cancer?
Abstract Number: 542

Is There Any Difference in RA Patients for Methotrexate Use Vs. Leflunomide Use As a Concomitant Treatment with Biological and Targeted Synthetic Dmards in Turkbio Registry?
Abstract Number: 668

Is Uric Acid Level a Predictor of Long-Term Renal Outcome in Lupus Nephritis?
Abstract Number: 1569

Isotretinoin Induced Seronegative Spondyloarthropathy: Magnetic Resonance Imaging As Diagnostic and Prognostic Biomarker
Abstract Number: 605

Ixekizumab Exhibits a Favorable Safety Profile during 24 Weeks of Treatment in Subjects with Active Psoriatic Arthritis: Integrated Safety Analysis of Two Randomized, Placebo Controlled, Phase III Clinical Trials
Abstract Number: 597

Ixekizumab Improves Patient-Reported Outcomes through 52 Weeks in Patients with Active Psoriatic Arthritis and Previous Inadequate Response to Tumor Necrosis Factor-Inhibitors
Abstract Number: 624

Ixekizumab Provides Sustained Improvement in Signs and Symptoms in Patients with Active Psoriatic Arthritis: Two Year Results from a Phase 3 Trial