2016 ACR/ARHP Annual Meeting Archives - Page 148 of 219

Abstract Number: 1491

M-Ficolin and MAp44 As Potential Markers of Subclinical Cardiovascular Comorbidity; Cardiac Evaluation By Coronary Computer Tomography and Myocardial Deformation of Left Ventricle in Early Rheumatoid Arthritis Patients
Abstract Number: 1933

M2 Macrophage Is the Predominant Phenotype in Airways Inflammatory Lesions in Patients with Granulomatosis with Polyangiitis
Abstract Number: 3082

Macrophage Activation Syndrome Is Identified By Coagulopathy, Hyperferritinemia, Fever, and Cytopenia in Hospitalized Patients, Resulting in Poor Outcome
Abstract Number: 1462

Magnesium Is a New Mediator Arthritis Severity and Joint Damage
Abstract Number: 934

Magnetic Resonance Imaging (MRI) Joint Space Narrowing Is an Independent Predictor of Radiographic and MRI Damage Progression in Patients with Early Rheumatoid Arthritis
Abstract Number: 1306

Magnetic Resonance Imaging Measures of Disease Activity in Rheumatoid Arthritis Patients Treated with Multiple Regimens of DMARD Therapy
Abstract Number: 1595

Magnitude and Duration of Early Response with Tofacitinib: Post-Hoc Analysis of Two Phase 3, Placebo-Controlled Studies
Abstract Number: 2513

Maintained Remission in Rheumatoid Arthritis over 7 Years in «Real Life Conditions» : A Monocentric Observational Study
Abstract Number: 1021

Maintaining Sufficient Serum Vitamin D Levels over 2 Years Is Associated with Reduced Knee Structural and Symptomatic Changes in Patients with Knee Osteoarthritis
Abstract Number: 2124

Maintenance of Chondrocyte Phenotypic Stability By TRPC6 Calcium Channel Activity
Abstract Number: 3226

Maintenance of Clinical Remission and Radiographic Non-Progression with MTX after Completion of 1 Year Initial Treatment with Certolizumab Pegol in Japanese Patients with Early Rheumatoid Arthritis
Abstract Number: 594

Maintenance of Improvements in Patients’ Physical Function, Workplace and Household Productivity, and Reduction in Caregiver Burden with 2 Years of Certolizumab Pegol Treatment in DMARD-Naive, Early RA Patients with Severe Progressive Disease
Abstract Number: 975

Maintenance Therapy Improves Long-Term Outcomes in Patients with Primary Angiitis of the Central Nervous System
Abstract Number: 1601

Maintenance Treatment Using Abatacept with Dose Reduction after Achievement of Low Disease Activity in Patients with Rheumatoid Arthritis (MATADOR) – a Prospective, Multicentered, Single Arm Clinical Trial
Abstract Number: 3024

Major Adverse Cardiovascular Events: Risk Factors in Patients with RA Treated with Tofacitinib
Abstract Number: 1188

Major Comorbidities of Idiopathic Inflammatory Myositis: A Population-Based Study Using 10 Years of Follow up from the National Health Insurance in Korea
Abstract Number: 1573

Major Histocompatibility Antigen HLA-DQ6.1 (DQA1*0103/DQB1*0601) Increases Rheumatoid Arthritis Risk Independent of Shared Epitope Among Indians
Abstract Number: 2878

Major Lymphocyte Populations Share a Common Interferon Signature but Express Cell Type-Specific Interferon Pathway Genes in SLE
Abstract Number: 2503

Making Room for RA Patient Symptoms into Treatment Decision: A Physician Perspective Study
Abstract Number: 2020

Making the Case for Self-Management Education: Marketing Lessons Learned from Qualitative Research
Abstract Number: 239

Malignancies in Korean Patients with Immunoglobulin G4-Related Disease
Abstract Number: 1953

Management and Outcomes of ANCA-Associated Vasculitis in Unselected Cases within a Large Health Region of England
Abstract Number: 1310

Management of Chronic Post-Chikungunya Rheumatic Disease: The Martinican Experience
Abstract Number: 2305

Mapping the Topography of Gout Flares: Solutions for Flare Reporting in Gout Clinical Trials
Abstract Number: 1616

Mavrilimumab, a Fully Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor-α Monoclonal Antibody: Long-Term Safety and Efficacy for up to 158 Weeks of Treatment in Patients with Rheumatoid Arthritis
Abstract Number: 2732

Meaningful Involvement of Patients in the Development of a Core Outcome Set for Psoriatic Arthritis
Abstract Number: 757

Measures of Disease Activity in Patients with Persistently Active Systemic Lupus Erythematosus (SLE): Results from a Two-Part 52 Week Pilot Study of Repository Corticotropin Injection (H.P. Acthar® Gel)
Abstract Number: 138

Measuring Agreement in the Ultrasonographic Evaluation of Disease Activity in Rheumatoid Arthritis Patients. a Latin-American Multicenter Exercise Assessing the Influence of Sonographer Experience and Expertise
Abstract Number: 1989

Mechanism of STAT3 Gain-of-Function in a Patient with JIA
Abstract Number: 2429

Mechanisms for the Development of Lung Fibrosis in Sting-Associated Vasculopathy with Onset in Infancy (SAVI)
Abstract Number: 2927

Mechanisms Regulating the Loss of Tregs in CD11c-Flip-KO Mice That Contribute to the Spontaneous Development of Inflammatory Arthritis
Abstract Number: 152

Median Nerve Stiffness Measured By Elastosonography in Patients with Rheumatoid Arthritis Is Higher Than Controls
Abstract Number: 2208

Mediators of the Relationship Between Pain and Disability in the Distal Upper Limb
Abstract Number: 1255

Medicare Part B Utilization By Rheumatology Health Care Providers As Related to Population Demographics from 2013
Abstract Number: 2393

Medication Use in the Juvenile Systemic Sclerosis Inception Cohort. ARE There Differences in the Diffuse and Limited Subset Patients?
Abstract Number: 1402

Meeting the Needs of Adolescents with Autoimmune Diseases, the Development of a Clinical Transition Pathway
Abstract Number: 2993

Membrane-Type 1 Matrix Metalloproteinase Controls Osteo- and Chondrogenesis By a Proteolysis-Independent Mechanism Mediated By Its Cytoplasmic Tail
Abstract Number: 2406

Mental Health Care for Adolescents with Rheumatologic Conditions: Perspectives from Pediatric Behavioral Health Providers in North America
Abstract Number: 1869

Mental Health Care in Systemic Sclerosis; Rates of Utilization and Associated Factors in the Scleroderma Patient-Centered Intervention Network Cohort
Abstract Number: 1141

Mentoring the Pediatric Rheumatology Community through the American College of Rheumatology/Childhood Arthritis and Rheumatology Research Alliance Mentoring Interest Group Network: A Five-Year Status Update
Abstract Number: 2784

Mesenchymal Stem Cells Ameliorate Lupus By Promoting T Cell Apoptosis Via Bcl-2/Bim Independent Pathway in MRL/Lpr Mice
Abstract Number: 1844

Mesenchymal Stem Cells Ameliorate the Deficiencies in Immunomodulatory and Phagocytic Capacities of Lupus Macrophages
Abstract Number: 3176

Meta-Analysis of SSc Clinical Trials with Molecular Gene Expression Data Suggests Potential Combination Therapies
Abstract Number: 1490

Metabolic and Cardio-Vascular Benefits of Hydroxychloroquine in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
Abstract Number: 289

Metabolic and Inflammatory Links to Development of Rotator Cuff Tear in Hand Osteoarthritis
Abstract Number: 1828

Metabolic Reprogramming in CD4+CD28-CXCR3intt-bethi cells and Its Relevance to Pathogenesis in Patients with SLE
Abstract Number: 1542

Metabolic Syndrome and Cardiovascular Risk Factors in Brazilian Patients with Established Rheumatoid Arthritis
Abstract Number: 2168

Metabolic Syndrome, All Cause Mortality and Atherosclerotic Cardiovascular Disease in Rheumatic Diseases
Abstract Number: 2532

Methotrexate Adherence in an Online Network of Patients with Rheumatoid Arthritis
Abstract Number: 1676

Methotrexate and Anti-Tumor Necrosis Treatment Improve Endothelial Function in Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
Abstract Number: 1315

Methotrexate and TNF-Blockers for Post Chikungunya Chronic Arthritis : The Martinican Experience
Abstract Number: 2261

Methotrexate Inhibits Intracellular Redox Signaling Induced By the Reactive Oxygen Species; Malondialdehyde and Acetaldehyde
Abstract Number: 1204

Methotrexate Is an Antibacterial Drug Metabolized By Human Gut Bacteria
Abstract Number: 1606

Metrotexate Treatment Inmunomodulate the Abnormal Cytokine Expression Present in NaïVe Rheumatoid Arthritis Patients
Abstract Number: 367

Microarray Analyses of Dorsal Root Ganglia for the Study of Pathways Contributing to Pain in Experimental Osteoarthritis
Abstract Number: 2836

Microparticles of Endothelial Origin in Women with Systemic LUPUS Erythematosus UNDER Treatment
Abstract Number: 2414

Microrna Associated with Active Systemic Juvenile Idiopathic Arthritis Regulate CD163 Expression in Polarized Macrophages through Two Distinct Mechanisms
Abstract Number: 810

Microrna-125b As a Potential Anti-Fibrotic and Anti-Apoptotic Regulator in Systemic Sclerosis
Abstract Number: 1034

Microrna-146a Controls Local Bone Destruction By Regulating Fibroblast Induced Osteoclastogenesis in Inflammatory Arthritis
Abstract Number: 1568

Microrna-17 Suppresses TNF-α Signaling By Reducing TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts
Abstract Number: 1672

Microrna-29a Activation of Canonical Wnt Signaling By Targeting LRP6 in Ankylosing Spondylitis
Abstract Number: 2997

Microrna-29a Curtails Synovitis in the Development of Knee Osteoarthritis By Disrupting VEGF
Abstract Number: 2099

Micrornas As Potential Modulators of Atherothrombosis in Antiphospholipid Syndrome
Abstract Number: 1666

Micrornas Mir-30b-5p, Mir-34a-5p, and Mir-431-3p Are Highly Expressed in the Plasma of Patients with Ankylosing Spondylitis
Abstract Number: 809

Micrornas Targeting the Wnt Signalling Pathway in Black African Patients with Diffuse Cutaneous Systemic Sclerosis
Abstract Number: 2897

Microvascular Function in Systemic Sclerosis Patients with End-Stage Vascular Manifestations of the Disease
Abstract Number: 590

Microvesicles in the Lungs of Early Rheumatoid Arthritis
Abstract Number: 2332

Midterm Outcome of Modular Metal-on-Metal Total Hip Arthroplasty
Abstract Number: 473

Migration, Colonization and Distribution of Bone Marrow Mesenchymal Stem Cells Transplanted in CIA Rats Were Traced By Green Fluorescent Protein
Abstract Number: 1056

Mind-Body Skills Training and Supportive Counseling for Depression in SLE: Positive Effects in a Randomized Controlled Trial
Abstract Number: 300

Mindfulness Predicts Treatment Response from Non-Pharmacological Therapy in Knee Osteoarthritis
Abstract Number: 2085

Minding the Gap: the Use of Nurse Practitioners and Physician Assistants in U.S. Rheumatology Practice to Affect Rheumatology Workforce Shortages
Abstract Number: 1765

Minimal Clinically Important Differences for Generic Patient Reported Outcomes Tools in SLE
Abstract Number: 2767

Minimal Disease Activity Among Psoriatic Arthritis Patients in Canada: Evaluation of Modified Minimal Disease Activity upon Elimination of Each Component
Abstract Number: 2758

Minimal Disease Activity Among Psoriatic Arthritis Patients in Canada: Which Unmet Criteria Are More Prevalent Among Responders?
Abstract Number: 1696

Minimal Disease Activity Is a Stable Measure of Therapeutic Response in Psoriatic Arthritis Patients Receiving Treatment with Adalimumab
Abstract Number: 299

Minimally Important Differences for Four Patient-Reported Outcomes Measurement Information System (PROMIS) Short Forms: Physical Function, Pain Interference, Depression, and Anxiety Among Adults with Knee Osteoarthritis
Abstract Number: 3253

Minimum Physical Function Needed to Walk 6000 Steps/Day in People with Knee Osteoarthritis
Abstract Number: 249

MiR-204-3p Associates with an Increased Level of IL-6 in Familial Mediterranean Fever By Targeting the PIK3 Signaling Pathway
Abstract Number: 3231

miR200b-5p Expression in Minor Salivary Glands (MSG): A Possible Predictor of Lymphoma Development in Sjögren’s Syndrome (SS)?
Abstract Number: 3075

Mitochondrial Genetic Variation, Copy Number and Susceptibility to Gout in the New Zealand Polynesian Population
Abstract Number: 2492

Mode of Administration in Rheumatoid Arthritis Treatments: An Exploration of Patient Preference for an ‘Ideal Treatment’
Abstract Number: 1862

Modelling Healthy and Scleroderma Fibrotic Skin in Vitro: Mechanical Stress Alters Macrophage Cytokine Expression and Triggers Signalling Via the Mechano-Sensing Transcription Factor Myocardin-Related Transcription Factor-a
Abstract Number: 3227

Modelling Primary Sjögren’s Syndrome Using Salivary Gland Stem Cells
Abstract Number: 1861

Modelling the Interaction Between Disease Microenvironment and Mesenchymal Cells in Systemic Sclerosis
Abstract Number: 2230

Models Using Claims-Based Administrative Data Are Poor Predictors of Rheumatoid Arthritis Disease Activity in VA Rheumatoid Arthritis (VARA) Patients
Abstract Number: 1470

Moderate to Severe Disease Activity in Rheumatoid Arthritis Is Associated with Myocardial 18f-Fluorodeoxyglucose (18F-FDG) Uptake
Abstract Number: 24

Modifiable Rheumatoid Arthritis Factors and Impact on Cardiovascular Risk
Abstract Number: 1461

Modification of Proteins with Malondialdehyde-Acetaldehyde and Citrulline Elicit Antibody Responses in DBA/1J Mice
Abstract Number: 2697

Modulator Role of Inducible Costimulator (ICOS) in Spondyloarthritis Animal Model
Abstract Number: 432

Monitoring Hepatitis B Screening Compliance in Patients with Rheumatoid Arthritis (RA) Receiving Anti-TNF Therapy
Abstract Number: 812

Monocytes/Neurotrophins/Myofibroblasts As a Novel Axis in Systemic Sclerosis
Abstract Number: 2280

Monosodium Urate Crystal-Induced Inflammation Promotes Osteocyte Expression of Pro-Resorptive and Inflammatory Mediators: Implications for Erosive Gout
Abstract Number: 2281

Monosodium Urate Monohydrate (MSU) Crystals Induces Cartilage Degeneration By Accelerating Hypertrophy and Mineralization.
Abstract Number: 1614

Monotherapy with Abatacept, Rituximab or Tocilizumab Is Not Associated with a Significantly Lower Long Term Retention Than Combination with Synthetic DMARD: Long-Term Registry Data in 4498 Real-Life Patients with Rheumatoid Arthritis
Abstract Number: 1170

Month of Birth Affects the Risk of Rheumatic Diseases: A Nationwide Case-Control Study
Abstract Number: 1026

Morphea-like Skin Lesions Reported in the Phase 3 Long-Term Odanacatib Fracture Trial and Extension in Postmenopausal Women with Osteoporosis
Abstract Number: 1351

Mortality and Prognostic Factors of Pneumocystis Pneumonia in Patients with Connective Tissue Diseases
Abstract Number: 1192

Mortality and Survival of Patients Diagnosed with GCA in Bergen (Western Norway) 1972-2012
Abstract Number: 1250

Mortality in Indigenous Populations of Canada, the United States, Australia, and New Zealand with Rheumatic Disease: A Systematic Review
Abstract Number: 3065

Mortality in Patients with Rheumatoid Arthritis and Interstitial Lung Disease Treated with First Line TNFi or Rituximab Therapies
Abstract Number: 523

Mortality Profile of Patients with Rheumatoid Arthritis in France and Its Change in 10 Years
Abstract Number: 1193

Mortality Rate According to Cause in Patients with Hemophagocytic Lymphohistiocytosis: A Meta-Analysis
Abstract Number: 3169

Mortality Trends in Systemic Lupus Erythematosus: A General Population-Based Cohort Study
Abstract Number: 1931

MRI Findings in Granulomatosis with Polyangiitis: Pachymeningitis and Implications in Quality of Life
Abstract Number: 1308

MRI of Bilateral Hands Prevents Clinicians from Failing to Detect Joint Damage of Patients with Rheumatoid Arthritis Compared to Scanning Unilateral Hand
Abstract Number: 306

MRI-Detected Cartilage Damage, Meniscal Damage, and Meniscal Extrusion Prior to Incident Radiographic Osteoarthritis and the Subsequent Trajectory of Joint Space Loss
Abstract Number: 1300

MRI-Detected Inflammation Is Associated with Functional Disability in Early Arthritis – Results of a Cross-Sectional Study
Abstract Number: 579

MRI-Detected Osteitis Is Not Associated with the Presence or Level of ACPA Alone, but with the Combined Presence of ACPA and RF
Abstract Number: 256

Muckle-Wells Syndrome in Chinese Adult Patients
Abstract Number: 2401

Mucocutaneous Lesions and Recurrent Fevers in Patients with Trisomy 8 Mosaicism and Chromosome 8 Duplication
Abstract Number: 2520

Multi-Biomarker Disease Activity (MBDA) Score and Prediction of Radiographic Progression in a Randomized Study of Patients with Early RA Treated with Methotrexate Alone or with Adalimumab
Abstract Number: 2798

Multi-Center Validation of Platelet Bound C4d, a Biomarker for Systemic Lupus Erythematosus
Abstract Number: 803

Multi-Organ RNA-Sequencing of Systemic Sclerosis (SSc) Patients Shows Reproducible Gene Expression Profiles Across Organ Systems
Abstract Number: 793

Multi-Parametric Model Development for Assessing Lupus Nephritis and Disease Activity
Abstract Number: 801

Multi-Tissue Gene Expression Pathway Analysis of Emerging Therapeutics in a TGFβ Dependent Mouse Model of Systemic Sclerosis
Abstract Number: 1380

Multicenter Prospective Study on the Role of Urinary HER2 As a Lupus Nephritis Biomarker
Abstract Number: 2411

Multiple Genetic Susceptibility Loci in Juvenile Idiopathic Arthritis Are Bound By a Set of Transcription Factors
Abstract Number: 1986

Murine Model of Arthritis Flare Identifies Tissue Resident Memory T Cells in Recurrent Synovitis
Abstract Number: 2405

Musculoskeletal Manifestations As Presenting Symptoms of Inflammatory Bowel Disease in Children and Adolescents
Abstract Number: 1325

Musculoskeletal Manifestations in Ebola Survivors
Abstract Number: 1710

Musculoskeletal Symptoms Preceding the Diagnosis of Psoriatic Arthritis – a Qualitative Exploration of the Patient Journey
Abstract Number: 158

Musculoskeletal Ultrasound Is a Sensitive Imaging Tool for the Assessment of Dynamic Changes of Bone Erosions in Inflammatory Arthritis: A Comparative Analysis with High-Resolution Peripheral Quantitatve Computed Tomography
Abstract Number: 2271

Mutation in Osteoprotegerin Gene: Early-Onset Osteoarthritis and Chondrocalcinosis in a US Family of Italian/German Ancestry
Abstract Number: 2430

Mutations in the Tyrosine-Protein Kinase Lyn Cause an Early-Onset Neutrophilic Vasculitis Syndrome
Abstract Number: 1824

Mycophenolate Mofetil Use Associates with Unique Biologic Changes in B Cell and T Regulatory Cell Pathways in SLE Patients
Abstract Number: 824

Mycophenolate Versus Placebo for the Treatment of Systemic Sclerosis-Related Interstitial Lung Disease
Abstract Number: 1393

Mycophenolic Acid Pharmacokinetics in Childhood-Onset Systemic Lupus Erythematosus Patients of Hispanic Ethnicity in a Single Center
Abstract Number: 6L

Myeloablative Autologous Transplantation of CD34+ -Selected Hematopoietic Stem Cells (HSCT) Vs Monthly Intravenous Cyclophosphamide (CYC) for Severe Scleroderma with Internal Organ Involvement: Outcomes of a Randomized North American Clinical Trial
Abstract Number: 1471

Myocardial 18f-Fluorodeoxyglucose (18F-FDG) Uptake in RA Patients without Clinical Cardiovascular Disease Is Higher Than in Controls and Decreases with Treatment
Abstract Number: 2055

Myocardial Abnormalities Are Associated with Corrected QT Interval in Patients with Rheumatoid Arthritis without Cardiac Symptoms Assessed Using Cardiac Magnetic Resonance Imaging
Abstract Number: 1494

Myocardial Structure, Function, and Fibrosis in Patients with Rheumatoid Arthritis and Matched Control Subjects
Abstract Number: 1819

Myocarditis in Systemic Lupus Erythematosus