2016 ACR/ARHP Annual Meeting Archives - Page 148 of 219

Abstract Number: 98

Daily Symptom Reports in a Smartphone-Based Study ‘Cloudy with a Chance of Pain’: Patterns of Attrition over the First Six Months
Abstract Number: 2747

Dapsa-28 May be Used Instead of Dapsa-66/68 in Psoriatic Arthritis
Abstract Number: 2206

Data on Treatment from Brazilian Fibromyalgia Patients Registry (EpiFibro)
Abstract Number: 1553

Declining Flare Rates in the First Five Years of RA Disease, but Not after
Abstract Number: 1201

Deconvolution of Immune Cell Proportions from Whole Blood RNA Using Next-Generation Sequencing
Abstract Number: 1531

Decrease in Bone Mineral Density during Three Months of Early RA Measured By DXR Predicts Radiographic Joint Damage after One Year
Abstract Number: 1636

Decrease of Tocilizumab in Rheumatoid Arthritis in Remission : A Multicenter Study
Abstract Number: 1089

Decreased B Cell Activation-Induced Apoptosis in Cells Overexpressing Interferon Regulatory Factor 5 (IRF5), a Gene Associated with Risk for Systemic Lupus Erythematosus and Other Autoimmune Diseases
Abstract Number: 2292

Decreased Endothelial and Smooth Muscle Responsiveness in the Vasculature of Gout Patients Compared with Healthy Controls: Relationship Between Flow- and Nitrate-Mediated Dilation, Serum Urate and CRP
Abstract Number: 2705

Decreased Expression of Autophagy Genes and Their Association with Spinal Damage in Patients with Ankylosing Spondylitis
Abstract Number: 3232

Decreased Expression of Micro-RNA 130a and Micro-RNA 708 in Type-1 Classical Dendritic Cells of Patients with Primary SS Indicates Their Dysregulation
Abstract Number: 1852

Decreased Expression of Sirtuin 7 By Lung Fibroblasts from Patients with Scleroderma Contributes to Elevated Collagen Production
Abstract Number: 658

Decreased Expression of Ten Micro-RNAs in Plasmacytoid Dendritic Cells of Patients with Primary SS Indicates Dysregulation on Multiple Levels
Abstract Number: 2304

Decreased Occurrence of Colon Cancer Among Gout Patients: Assessment By Physician Diagnosis and Colonoscopy
Abstract Number: 1820

Dectin-1 on Monocytic Cells Mediates Aberrant Innate and Adaptive Immune Responses in Patients with Systemic Lupus Erythematosus
Abstract Number: 463

Deficiency of Transmembrane Protein VISTA (V-domain Immunoglobulin Suppressor of T-cell Activation) Ameliorates Murine Collagen-II Antibody-Induced Arthritis
Abstract Number: 2132

Deficient Autophagy Induces Premature Senescence in Aging and Osteoarthritis
Abstract Number: 2556

Deficient Expression of the Novel Rheumatoid Arthritis (RA) Risk Gene, LBH, Induces S Phase Arrest in RA Fibroblast-like Synoviocytes (FLS)
Abstract Number: 1050

Defining Low Disease Activity in Systemic Lupus Erythematosus
Abstract Number: 832

Defining Skin Ulcers in Systemic Sclerosis: A Systematic Literature Review of Skin Ulcer Definitions and a Preliminary Consensus-Based New SSc Skin Ulcer Definition
Abstract Number: 1653

Delineating the Effects of Rheumatoid Arthritis Pharmacotherapies on Vascular Inflammation: Rationale and Design of a Clinical Trial
Abstract Number: 1821

Demethylated CD4+CD28+KIR+CD11ahi T Cells Are Characterized By a Pro-Inflammatory Transcriptome and Interact with Genetic Risk to Predict Disease Activity in Lupus
Abstract Number: 1755

Dendritic Cell-Specific Loss of Caspase 8 Incites Symptoms of Neuropsychiatric Systemic Lupus Erythematosus
Abstract Number: 1441

Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Knockout Attenuates Arthritis Progression and Systemic Inflammation in TNF-Tg Arthritis Mouse Models
Abstract Number: 337

Denosumab Treatment for 10 Years in Postmenopausal Women with Osteoporosis Was Associated with Substantially Lower Fracture Incidence Relative to Their Baseline FRAX-Predicted Probability
Abstract Number: 3043

Dense Genotyping of Immune Related Loci in a Multi-Ethnic Behçet’s Disease Cohort Identifies Genetic Associations in a Long Noncoding RNA Near QSOX2, RASIP1/FUT2, and IL12A-AS1
Abstract Number: 2875

Depressed Serum IgM Levels in SLE Are Restricted to Defined Subgroups
Abstract Number: 2164

Depression and the Risk of Psoriatic Arthritis Among Patients with Psoriasis: A Population-Based Cohort Study
Abstract Number: 1535

Depression in Rheumatoid Arthritis
Abstract Number: 1967

Depression Is a Risk Factor for Low Treatment Adherence in African American People with Systemic Lupus Erythematosus
Abstract Number: 1771

Depression Is Associated with a Poorer with Health-Related Quality of Life in Patients with Systemic Lupus Erythematosus
Abstract Number: 2752

Depression Is Associated with Worse Outcomes in Axial Spondyloarthropathy Population
Abstract Number: 3238

Depression Symptoms throughout the Lifespan in a Low-Income, Minority Cohort of Lupus Patients: Who Is at Risk?
Abstract Number: 2163

Depressive Symptoms in Patients Consulting for the First Time at the Division of Rheumatology
Abstract Number: 2067

Dermal Fibroblasts from Patients with Lupus Nephritis Express an Anti-Fibrotic Transcriptome
Abstract Number: 2081

Dermal Temperature Is an Excelent Prognostic Indicator to Guide RA Therapy
Abstract Number: 2445

Dermatomyositis and Pregnancy: Assessment of Disease Activity and Pregnancy Outcomes Complicated By Maternal Dermatomyositis
Abstract Number: 1269

Description of Radiographic Hip Measurements By OA Status in a Large Community-Based Study of African American and White Men and Women
Abstract Number: 1207

Design of a Multiplex Serum Proteome Assay to Monitor Biologic Drug Response in Rheumatoid Arthritis Patients
Abstract Number: 550

Despite Early Improvement and Limited Self-Reported Disability, Patients with Rheumatoid Arthritis Still Have Impaired Grip Strength 5 Years after Diagnosis
Abstract Number: 58

Detecting Novel Candidate Risk Genes in Rheumatoid Arthritis with Gene-Based Association Testing
Abstract Number: 1902

Detecting the Pulmonary Vascular Involvement and the Changes in Gene Activation Profiles at Early Stage of Systemic Sclerosis in Patients with Raynaud Phenomenon
Abstract Number: 2690

Detection of Dorsal Root Ganglionitis with Magnetic Resonance Neurography in Sensory Ataxic Neuropathy Associated with SjöGren’s Syndrome
Abstract Number: 156

Detection of Finger Joint Osteophytes and Bone Erosions By Ultrasound; A Comparison to Computed Tomography and Histology
Abstract Number: 2680

Determinants of Fatigue in Patients with Primary SjöGren’s Syndrome and Impact of Fatigue on Patients’ Treatments: A Cohort Study
Abstract Number: 3233

Determinants of Pain, Fatigue, Physical Function and Social Participation in SLE Patients, Measured with Patient Reported Outcomes Measurement Information System (PROMIS®) Computerized Adaptive Tests
Abstract Number: 3186

Determinants of Patient-Physician Discordance in Global Assessment in Psoriatic Arthritis and Levels of Discordance According to Disease Activity: A Multicenter European Study
Abstract Number: 1480

Determination of the Lipid Profile in Active Disease Leads to Incorrect Cardiovascular Risk Prediction in Early Rheumatoid Arthritis Patients
Abstract Number: 1903

Determining Disease Course in Localized Scleroderma: A Prospective Cohort Study
Abstract Number: 1051

Determining the Minimal Clinically Important Difference for Improvement for Systemic Lupus Erythematosus Disease Activity Index-2000 Responder Index-50 (S2K RI-50)
Abstract Number: 2022

Developing a Gout Needs Assessment Incorporating Patient Perspective on Self-Management, Self-Efficacy and Disease Specific Knowledge, to Inform a Patient Education Initiative
Abstract Number: 2397

Developing a Role for 18f-Flurodeoxyglucose PET/MRI in Pediatric Takayasu Arteritis
Abstract Number: 422

Developing a Staff-Driven Electronic Smoking Cessation Referral Program in Rheumatology Clinics
Abstract Number: 686

Development and Evaluation of the Combined Ankylosing Spondylitis Spine Score (CASSS) for the Assessment of Spinal Radiographic Outcome
Abstract Number: 3060

Development and Implementation of a Question-Based Tool Promoting Learning of Relevant Epidemiology and Biostatistics in Rheumatology: The Critical Literature Assessment Skills Support – Rheumatology (CLASS-Rheum) Pilot
Abstract Number: 794

Development and Initial Validation of a Novel Lupus Disease Activity Index to Account for Glucocorticoids: Sledai-2K Glucocorticoids Index (SGI)
Abstract Number: 3005

Development and Initial Validation of the “MH Score”, a New Diagnostic Tool That Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome
Abstract Number: 408

Development and Initial Validation of the Parent and Child Versions of the Juvenile Arthritis Disease Activity Score
Abstract Number: 3130

Development and Pilot Testing of an Online Educational Tool for Gout Patients — Mygoutcare®
Abstract Number: 680

Development and Preliminary Validation of the Computed Tomography Sacroiliac Structural Score for Assessment of Structural Lesions in Axial Spondyloarthritis
Abstract Number: 1370

Development and Validation of a Composite Disease Activity Score for Juvenile Dermatomyositis
Abstract Number: 1298

Development and Validation of Berlin and Sparcc MRI Sacroiliac Joint Scoring Methods for the Semi-Axial Scan Plan
Abstract Number: 1945

Development and Validation of Case-Finding Algorithms for the Identification of Patients with ANCA-Associated Vasculitis and Large-Vessel Vasculitis in Healthcare Administrative Databases
Abstract Number: 3141

Development of a Glucocorticoid Toxicity Index Using Multi-Criteria Decision Analysis
Abstract Number: 3076

Development of a Matrix-Binding Interlukin-1 Receptor Antagonist Fusion Protein for Extended Retention in the Joint Tissues
Abstract Number: 709

Development of a Novel Medication Adherence Prediction Model for Patients with Ankylosing Spondylitis Based on Results from a Global Clinical Study
Abstract Number: 1160

Development of a Shared Decision Making Tool for Osteoporosis Treatment
Abstract Number: 837

Development of a Skin-Specific Scleroderma Patient Reported Outcome Instrument
Abstract Number: 1156

Development of a Taxonomy of Patient Engagement in Health Research
Abstract Number: 2021

Development of an Item Bank on Disease and Treatment Associated Knowledge of Rheumatoid Arthritis to Improve Patient Engagement in Care
Abstract Number: 3117

Development of Autoimmune Diseases and Genetic Predisposition in Children with Neonatal Lupus and Their Unaffected Siblings
Abstract Number: 516

Development of RA Patient Preference Phenotypes
Abstract Number: 708

Development of Spondyloarthritis-Features in Patients with Chronic Back Pain over a One-Year Course: Data from the Spondyloarthritis Caught Early (SPACE)-Cohort
Abstract Number: 2089

Deviation of T and B Cell Subset and Its Association with Single Nucleotide Polymorphisms in Patients with Antiphospholipid Syndrome
Abstract Number: 3047

Diabetes and BMI Modify the Association Between Painful Hip OA and All-Cause Mortality
Abstract Number: 20

Diabetes and Other Comorbidities in Rheumatoid Arthritis Patients Starting a Biologic DMARD: A Multi-Database Cohort Study
Abstract Number: 2684

Diagnosis of Systemic Diseases in Patients Presenting with Sicca Syndrome Using a Minimally-Invasive Minor Salivary Gland Biopsy: Analysis of 901 Patients
Abstract Number: 694

Diagnostic Delay Leads to Worse Response to Treatment
Abstract Number: 1247

Diagnostic Modeling of Rheumatoid Arthritis in Oklahoma Tribal Members Using Soluble Mediators
Abstract Number: 1667

Diagnostic Value of Anti-CD74 Antibodies in Axial Spondyloarthritis: Results from a Population with Low HLA-B27 Prevalence Background
Abstract Number: 679

Diagnostic Value of MR Enterography As a Complementary Intervention to Colonoscopy in Axial Spondylarthritis Patients with Chronic Non-Bloody Diarrhea
Abstract Number: 3201

Diagnostic Value of Quantitative Sialoscintigraphy Compared to Labial Salivary Gland Biopsy in Patients with Suspected SjöGren’ Syndrome
Abstract Number: 1476

Diastolic Dysfunction in Patients with Rheumatoid Arthritis: Predictors of Longitudinal Progression over Five Years
Abstract Number: 2127

Dicam Promotes Proliferation and Hypertrophic Differentiation of Chondrocyte through Indian Hedgehog Signaling of Primary Cilia
Abstract Number: 1018

Dietary Intake of Fiber and Risk of Knee Osteoarthritis
Abstract Number: 2031

Dietary Patterns and Radiographic Progression of Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Abstract Number: 2030

Difference in Risk Factor Profile Between Medial and Lateral Compartment Involvement in Tibiofemoral Knee Osteoarthritis
Abstract Number: 2828

Difference of d-Dimer Between Two Time Points Predicts Prognosis of Admitted Patients with SLE Flare up
Abstract Number: 537

Differences and Associated Factors in General Disability and Hand Disability Between Patients with Rheumatoid Arthritis and Psoriatic Arthritis
Abstract Number: 1778

Differences Between Early and Late Cardiovascular Disease in a Population-Based Cohort of Systemic Lupus Erythematosus Patients
Abstract Number: 16

Differences Between Patient and Physician Global Assessment on Rheumatoid Arthritis Disease Activity Status in High and Lower Income Countries Contribute to Inequity
Abstract Number: 1048

Differences in Clinical Manifestations of SLE Across Four Racial/Ethnic Groups: The California Lupus Surveillance Project (CLSP)
Abstract Number: 557

Differences in Clinical Outcomes in Different Socio-Economic and Racial Groups with Rheumatoid Arthritis: Data from National Inpatient Sample
Abstract Number: 3118

Differences in Disease Phenotype, Management and Outcomes of Children with Juvenile Idiopathic Arthritis throughout the World – Analysis of 8,325 Patients Enrolled in the Epoca Study
Abstract Number: 2002

Differences in Features of Chronic Back Pain in First Degree Relatives of Patients with Ankylosing Spondylitis (AS) Compared to the U.S. Population
Abstract Number: 575

Differences in Histological Scores and Histoclinical Correlations in ACPA- Versus ACPA+ Rheumatoid Arthritis Patients
Abstract Number: 34

Differential Analgesic Pharmacological Effects on Brain Connectivity in Fibromyalgia (FM)
Abstract Number: 2284

Differential Effect of MSU-Crystal Induced Inflammation on Macrophage Polarization
Abstract Number: 1444

Differential Expression of Wnt Inhibitors before and after Joint Inflammation Onset in Rat Arthritis Could Partly Explain Paradoxical Effect of Sclerostin Inhibition
Abstract Number: 2423

Differential Interferon Score Expression in the Peripheral Blood in Mendelian Inflammatory Interferonopathies Versus Juvenile Dermatomyositis (JDM) Subtyped By Myositis Autoantibodies and Disease Activity
Abstract Number: 1978

Differential Pattern of Doppler Signals at Lower Extremity Entheses of Healthy Children
Abstract Number: 1219

Differential Peripheral Blood DNA Methylation Patterns Are Predictive of Radiographic OA Progression
Abstract Number: 1654

Differential Serum Protein Expression in Groups of Psoriatic Arthritis Patients Characterised By Specific HLA Genotypes and Clinical Features
Abstract Number: 1203

Differential Synovial Expression Patterns in Early Osteoarthritis Predict Pain and Progression of Joint Damage
Abstract Number: 2713

Differentially Expressed Microrna As Candidate Biomarker for Disease Activity in Ankylosing Spondylitis
Abstract Number: 2952

Differentiation Between Neurosarcoidosis and Primary CNS Vasculitis Based on Clinical and Cerebrospinal Fluid Parameters
Abstract Number: 1102

Differentiation of Spongiosa-Derived Mesenchymal Stromal Cells from Osteoporosis and Osteoarthritis Patients Are Influenced By Adipokines
Abstract Number: 601

Differing Contribution of Methotrexate Polyglutamation to Infliximab and Adalimumab Exposure As Compared to Etanercept
Abstract Number: 3078

Diffuse Idiopathic Skeletal Hyperostosis and Diabetes- Using Genetic Risk Scores to Explore the Association
Abstract Number: 266

Diffuse Idiopathic Skeletal Hyperostosis and Obesity- Is There a Causal Relationship?
Abstract Number: 267

Diffuse Idiopathic Skeletal Hyperostosis: Can We Identify Different Clinicoradiological Patterns?
Abstract Number: 974

Diffuse Scleroderma, Male Sex, and Myopathy Are Associated with Severe Gastrointestinal Dysmotility in Scleroderma
Abstract Number: 724

Diminished Spinal Radiographic Progression during Long-Term Treatment with TNF-α Inhibitors in Ankylosing Spondylitis Patients at Risk of Poor Radiographic Outcome
Abstract Number: 2069

Dipeptidyl-Peptidase-4 (DPP4) Positive Fibroblast Subpopulation Promotes Fibrosis and Are a Molecular Target for Treatment of Fibrosis
Abstract Number: 552

Disability in Early Rheumatoid Arthritis, Course and Predictors
Abstract Number: 2922

Disability, Fatigue, and Their Associates in Early Diffuse Cutaneous Systemic Sclerosis
Abstract Number: 1360

Discontinuation Causes of Biological Therapies: Over a Five-Year Period. Biobadasar
Abstract Number: 2728

Discontinuation of Biologic Therapy in Patients with Ankylosing Spondylitis—Data from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry
Abstract Number: 1028

Discontinuation of Denosumab and Associated Vertebral Fracture Incidence: Analysis from a Phase 3 Placebo-Controlled Study of Denosumab and Its Open-Label Extension
Abstract Number: 1646

Discontinuation of Methotrexate or Glucocorticoids in Patients with Rheumatoid Arthritis Treated with Tofacitinib: Clinical Efficacy Data from Long-Term Extension Studies
Abstract Number: 534

Discordance Between Physician-Stated Remission and 28-Joint Disease Activity Score (DAS28)-Defined Remission in Rheumatoid Arthritis Patients
Abstract Number: 409

Discordance Between Physician, Patient, and Parent Disease Assessment Scores in Juvenile Idiopathic Arthritis
Abstract Number: 2465

Discordance Between Tender and Swollen Joint Count and Patient’s and Evaluator’s Global Assessment May Reduce Likelihood of Remission in Rheumatoid Arthritis
Abstract Number: 897

Discordance Rates of Bilateral Temporal Artery Biopsies: A Retrospective Analysis
Abstract Number: 1083

Discovery and Subsequent Diagnostic Verification of Autoantibodies Against the Major Vault Protein (MVP) in Systemic Lupus Erythematosus
Abstract Number: 2120

Discovery of a Small Molecule Inhibitor of the Wnt Pathway (SM04690) As a Potential Treatment for Degenerative Disc Disease
Abstract Number: 1104

Discovery of a Small Molecule Inhibitor of the Wnt Pathway (SM04755) As a Potential Topical Treatment for Chronic Tendinopathy
Abstract Number: 2704

Discovery of a Small Molecule Inhibitor of the Wnt Pathway (SM04755) As a Potential Topical Treatment for Psoriasis
Abstract Number: 1856

Discovery of a Small Molecule Inhibitor of the Wnt Pathway (SM04755) As a Potential Topical Treatment for Scleroderma
Abstract Number: 1079

Discovery of Novel Autoantigens in Sjogren’s Syndrome with Potential for Subgrouping of Disease
Abstract Number: 418

Discrepancy in Reported and Actual Rates of Counseling on Teratogenicity and the Need for Contraception When Initiating Mycophenolate in Women of Childbearing Age
Abstract Number: 746

Discrepancy in Rituximab-Induced B-Cell Depletion in Peripheral Blood and the Kidney and Relationship with Clinical Response in Patients with Lupus Nephritis
Abstract Number: 2719

Discriminating Value of Calprotectin in Disease Activity and Progression of Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis
Abstract Number: 404

Disease Activity and Damage in Juvenile Idiopathic Arthritis: Comparison Between “Methotrexate” and “Biologic” Era
Abstract Number: 531

Disease Activity and Physical Fatigue As Related to Adherence and Health Literacy in Patients with Rheumatoid Arthritis
Abstract Number: 1407

Disease Activity Trackers to Support Treat to Target Strategies: A Needs Assessment Survey
Abstract Number: 600

Disease Activity Trends after Dose Escalation of Infliximab (Remicade) – Results from United States Consortium of Rheumatology Researchers of North America Registry
Abstract Number: 1944

Disease Activity, Glucocorticoid Exposure, and Rituximab Determine Body Composition Changes during Induction Treatment of ANCA-Associated Vasculitis
Abstract Number: 585

Disease Associated Anti-Citrullinated Protein Memory B Cells in Rheumatoid Arthritis Persist in DAS Remission
Abstract Number: 1731

Disease Burden and Impact of Certolizumab Pegol Treatment on Workplace and Household Productivity Across Working Age Rheumatoid Arthritis, Psoriatic Arthritis and Axial Spondyloarthritis Patients
Abstract Number: 1522

Disease Burden in Rheumatoid Arthritis (RA) Patients Who Have Secondary Osteoarthritis (OA) Is Lower Than in OA but Higher Than in RA with No Secondary OA
Abstract Number: 1521

Disease Characteristics and Change of Arthritis Activity According to Treatment in Hepatitis B Surface Antigen Positive Rheumatoid Arthritis Patients
Abstract Number: 127

Disease Characteristics and Outcomes in African-American Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: a High Risk Group for Poor Outcomes
Abstract Number: 2976

Disease Flares and Persistent Low-Level of Disease: Long-Term Outcome in a Cohort of Patients with BehçEt’s Disease
Abstract Number: 1331

Disease Patterns and Long Term Outcome Amongst Patients with Relapsing Polychondritis – Single Centre Experience
Abstract Number: 1730

Disease Progression Among Non-Achievers of Minimal Disease Activity in Psa Patients Treated with Infliximab or Golimumab
Abstract Number: 298

Disease Progression in Osteoarthritis Is Driven By Multiple Disease Parameters Leading to Comparable Levels of Joint Destruction
Abstract Number: 248

Disease Severity and High Attack Frequency Under Colchicine Treatment Is Associated with Increased Carotid Intima Media Thickness in FMF
Abstract Number: 2112

Disease-Activity Associated Autoantibodies to Malondialdehyde-Modified Proteins Can be Isolated from Synovial B Cells in RA
Abstract Number: 1970

Disparities in Access to Specialist Care at the Time of Diagnosis of Systemic Lupus Erythematosus
Abstract Number: 899

Disparities in Disease Characteristics, Treatment Pattern and Comorbidities in 1,858 Patients with Polymyalgia Rheumatica, Giant Cell Arteritis or Both Diseases
Abstract Number: 1256

Disparities in Total Knee Replacement: Population Losses in Quality-Adjusted Life Years Due to Differential Offer, Acceptance, and Complication Rates in African Americans
Abstract Number: 1747

Dissecting the Role of Single Complement Deficiencies in a Novel Model for Apoptotic Cell-Induced Lupus
Abstract Number: 2558

Dissociation of the Inhibitory Apoptosis Stimulating Protein of p53 (iASPP) Binding with Transcription Factor p73 Induces Synovial Fibroblast Apoptosis in the Rheumatoid Joint
Abstract Number: 937

Distal Interphalangeal Joint Erosions Assessed By HR-pQCT in Patients with Psoriatic Onycholysis
Abstract Number: 1628

Distinct Baseline Serum Molecular Profile and Pharmacodynamic Effects of Sirukumab, an Anti–IL-6 Cytokine Monoclonal Antibody, in Asian-Pacific Patients with Active Rheumatoid Arthritis Despite DMARD or Anti-Tnfα Therapy Across Two Global Phase 3 Trials
Abstract Number: 1388

Distinct Clinical Correlates of Immune Thrombocytopenic Purpura at Diagnosis of Childhood-Onset and Adult SLE
Abstract Number: 2880

Distinct Metabolic Pathways Regulate Lipid Antigen Presentation By Monocytes and B Cells: Implications for SLE Patients with Pre-Clinical Atherosclerotic Plaque
Abstract Number: 2571

Distinct Oral and Fecal Community Profiles Enriched in Opportunistic Pathogens in RA Patients and First Degree Relatives Are Influenced By Environmental Risk Factors, Including Smoking, Dental History and Lung Infection
Abstract Number: 151

Distinct Phenotypes in Palindromic Rheumatism: Ultrasound and MRI during Palindromic Flares
Abstract Number: 3220

Distinct Single Cell Gene Expression Signatures of Monocyte Subsets Differentiate Between TNF-Alpha Inhibitor Treatment Response Groups in Rheumatoid Arthritis
Abstract Number: 834

Distinctive Clinical Phenotype of Anti-Centromere Antibody Positive Diffuse Systemic Sclerosis
Abstract Number: 2204

Distinctive Personality Profiles of Fibromyalgia and Chronic Fatigue Syndrome Patients
Abstract Number: 1321

Distinguishing Features of Polymicrobial Septic Arthritis
Abstract Number: 1745

Disturbance of Renal Circadian Rhythm in Lupus Nephritis
Abstract Number: 2496

DMARD, Biologic and Small Molecule Drug Use Among ACPA Positive and ACPA Negative RA Patients in a Tertiary Referral Center
Abstract Number: 2108

DNA Hypomethylation in Promoter Region of Zbtb38 Gene Ultimately Leads to Downregulated Expression of Anti-Inflammatory IL1r2 in Experiential Model of Rheumatoid Arthritis
Abstract Number: 1093

DNA Methylation Defines Joint Specific Differences in Synovial Fibroblasts from OA and RA Patients
Abstract Number: 618

Do Canadian Rheumatologists Actually Treat to Target Once a Biologic Has Been Initiated? an Analysis from a Prospective, Observational Registry
Abstract Number: 3085

Do Depression and Anxiety Reduce the Chance of Remission in Rheumatoid Arthritis and Psoriatic Arthritis?
Abstract Number: 1317

Do Patients with MRSA-Positive Septic Arthritis Differ Clinically from Non-MRSA-Positive Counterparts?
Abstract Number: 2450

Do Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis Have Reduced Fertility and Parity? a Systematic Review
Abstract Number: 2218

Do Some Patients with Distal Upper Limb Pain Benefit More Than Others from Advice to Remain Active?
Abstract Number: 578

Do Specific Anti-Citrullinated Antibodies Predict Different Phenotype of Rheumatoid Arthritis?
Abstract Number: 2743

Do Specific Entheseal Points in Spa Patients Impact Patient Reported Outcomes? Implications for Clinical Practice
Abstract Number: 1674

Do TNF Inhibitors Change the Progression of Sacroiliitis?
Abstract Number: 2660

Do Ultrasonographic Lesions of Salivary Glands Evolve in SjöGren Patients during Follow-up ?
Abstract Number: 2736

Do Validated Tools of Disease Activity in Ankylosing Spondylitis Measure Fibromyalgia Pain?
Abstract Number: 3112

DOCK8 Associates with STAT5 and Promotes Regulatory T Cell Function
Abstract Number: 2447

Does a History of Abnormal Pap Smear or Preceeding HPV Infection Affect Humoral Immune Response to Quadrivalent Human Papilloma Virus (qHPV) Vaccine in Women with Systemic Lupus Erythematosus (SLE)
Abstract Number: 2348

Does Arthritis in Other Joints and Spine Influence the 1-Year Outcome of Total Hip Replacement? a Prospective European Multicenter Cohort Study Measuring the Influence of Musculoskeletal Morbidity
Abstract Number: 697

Does Axial Spondyloarthritis Phenotype Correlate with Imaging Morphotype?
Abstract Number: 704

Does Change in Disease Activity over One Year Result in Change in Health-Related Quality of Life in Early Axial Spondyloarthritis Patients?
Abstract Number: 2514

Does Combination of Conventional Synthetic Disease Modifying Antirheumatic Drug with Anti-TNF Influence the Long Term Retention Compared to Anti-TNF Monotherapy in Psoriatic Arthritis? an Analysis from Rhumadata® over 12 Years
Abstract Number: 2769

Does Gender Make a Difference in “Composite Psoriatic Disease Activity Index (CPDAI)” in Patients with Psoriatic Arthritis?
Abstract Number: 1517

Does Inflammatory Arthritis Really Improve during Pregnancy? a Systematic Review and Meta-Analysis
Abstract Number: 3002

Does Morbid Obesity Negatively Affect Patient Reported Outcomes Following Total Knee Arthroplasty?
Abstract Number: 2339

Does Physical Activity Change after Total Hip or Knee Arthroplasty: A Systematic Review and Meta-Analysis
Abstract Number: 1251

Does Preconsult Electronic Exchange Affect Postconsult Diagnosis?
Abstract Number: 108

Does Receiving Physical Therapy for Knee Osteoarthritis Impact Downstream Healthcare Utilization?
Abstract Number: 2716

Does Secretory Immunoglobulin a Influence Disease Activity in Patients with Reactive Arthritis and Undifferentiated Spondylarthritis?
Abstract Number: 1234

Does SLE Care in a Lupus Clinic Result in Higher Quality Scores Than in General Rheumatology Clinics?
Abstract Number: 562

Does Surgical Intervention to the Upper Extremity Make the Patients with Rheumatoid Arthritis Happy?
Abstract Number: 729

Does the Presence of Multiple Spondyloarthritis-Features in Patients with Chronic Back Pain Always Lead to Diagnosis of Axial Spondyloarthritis?
Abstract Number: 1694

Does Treat to Target or Achieving Remission Improve Radiographic Outcome in Psa?
Abstract Number: 1036

Dominant B-Cell Receptor Clones in Peripheral Blood Predict Onset of Arthritis in Individuals at Risk for Rheumatoid Arthritis
Abstract Number: 2035

Dosage Contribution of a Non-Classical HLA Gene, HLA-Doa, to the Risk of Rheumatoid Arthritis
Abstract Number: 3013

Dose Reduction or Discontinuation of Biological Therapy in Patients with Rheumatoid Arthritis in Remission – 1-Year Results of a Guideline-Directed Longitudinal Cohort Study
Abstract Number: 1644

Dose Selection of Filgotinib, a Selective JAK1 Inhibitor, for Rheumatoid Arthritis Phase 3 Studies: Exposure-DAS28 and ACR Modeling Approach
Abstract Number: 2359

Dose-Related Risks of Cardiovascular, Gastrointestinal, and Renal Adverse Events Associated with Meloxicam Among Patients with Osteoarthritis: An Observational Study Using US Claims Data
Abstract Number: 2480

Dose-Related Short Term Clinical Response to Initial Treatment with Methotrexate in Mono- and Combination Therapy in Early Rheumatoid Arthritis Patients – a Meta-Regression Analysis
Abstract Number: 1597

Dose-Response Modeling Is a Useful Tool to Determine Doses for Phase 3: Experience from Olokizumab
Abstract Number: 1754

Double-Negative T (DNT) Cell over-Expressing PD-1 and Helios Is Responsible for Lupus Tissue Injury in Systemic Lupus Erythematosus (SLE): Direct Proof That Increased Interferon Alpha (IFNα) Expression Is Sufficient to Induce SLE in Ifnα-Transgenic Mice
Abstract Number: 808

Down-Regulation of microRNA-126 in Scleroderma Microvascular Endothelial Cells (MVECs) Is Associated with Impaired Responses to Vascular Endothelial Growth Factor (VEGF) and Defective Angiogenesis
Abstract Number: 1750

Down-Regulation of microRNA-200a-3p, Targeting C-Terminal Binding Protein-2 (CtBP2), Is Involved in Hypoproduction of IL-2 in SLE-Derived T Cells
Abstract Number: 784

Drivers of the SLE Responder Index (SRI) Endpoint in Clinical Trials of SLE
Abstract Number: 11

Drug Prescribing Trends in Adults with Rheumatoid Arthritis: A Population-Based Comparative Study from 2005-2014
Abstract Number: 2527

Drug Retention of Biologics in Rheumatoid Arthritis Patients: The Role of Baseline Characteristics and Impact of Time-Varying Factors
Abstract Number: 327

Drug Retention Rate of Oral Bisphosphonate in Patients with Rheumatoid Arthritis
Abstract Number: 2647

Drug Trough Serum Levels Rather Than Antidrug Antibodies Explain Disease Flares in Patients with Rheumatoid Arthritis and Psoriatic Arthritis Treated with TNF Inhibitors in Clinical Remission/Low Disease Activity: A One Year Prospective, Multicenter Study (INMUNOREMAR)
Abstract Number: 3225

Dual Cytokine Inhibition with ABT-122, a Tnf– and IL-17–Targeted Dual Variable Domain Immunoglobulin (DVD-Ig™): Results from a 24-Week Open-Label Extension Study in Patients with Rheumatoid Arthritis
Abstract Number: 481

Dual Effect of 3-Bromopyruvate on Both Th17 and Treg Cell Differentiation and Dendritic Cell Activation Ameliorates Autoimmune Arthritis in Mice
Abstract Number: 36

Dysautonomia and Osteoporosis in 2300 Ehlers-Danlos Hypermobile Patients, As Defined By the Brighton Criteria
Abstract Number: 73

Dysregulation of Hypomethylated Age-Related CpG Sites Characterize T-Cells and Monocytes from Treatment Naive Rheumatoid Arthritis Subjects
Abstract Number: 1841

Dysregulation of the Splicing Machinery Components in Leukocytes from Patients with Systemic Lupus Erythematosus: Influence on Autoimmune and Atherothrombotic Mechanisms