Abstract Number: 1196 • ACR Convergence 2021
Morning Stiffness Already Associates with Systemic Inflammation and Subclinical Joint Inflammation in the Pre-RA Phase of Arthralgia
Background/Purpose: Morning stiffness (MS) is characteristic for Rheumatoid Arthritis (RA) and associates with markers of systemic and local inflammation in RA-patients. In patients with arthralgia,…Abstract Number: 0557 • ACR Convergence 2020
The Joint Association of Steps/day and Typical Sedentary Bout Length with Worsening Knee Cartilage Damage over Two Years: The MOST Study
Background/Purpose: Knee cartilage requires loading, e.g., walking, to remain healthy. When cartilage is deprived of loading, i.e., during bouts of sedentary time, it becomes vulnerable…Abstract Number: 1486 • ACR Convergence 2020
Long-term Efficacy and Safety of Intra-articular Sprifermin in Patients with Knee Osteoarthritis: Results from the 5-Year Forward Study
Background/Purpose: The 5-year Phase II FORWARD study assessed the efficacy and safety of the potential disease-modifying osteoarthritis drug (DMOAD) sprifermin (recombinant human fibroblast growth factor…Abstract Number: 2024 • ACR Convergence 2020
Effects of Filgotinib on Spinal Lesions in Patients with Ankylosing Spondylitis: Magnetic Resonance Imaging Data from the Placebo-Controlled, Double‑Blind, Randomized TORTUGA Trial
Background/Purpose: The oral, selective Janus kinase 1 inhibitor filgotinib (FIL) significantly improved Spondyloarthritis Research Consortium of Canada (SPARCC) MRI inflammation scores (bone marrow edema) in…Abstract Number: 0708 • ACR Convergence 2020
Differences in Treating Knee Osteoarthritis by Clinician Specialty
Background/Purpose: Current treatment of knee osteoarthritis (OA) is focused primarily around pain relief offering sustained mobility and prioritizing symptom relief over disease progression potentially impacts…Abstract Number: 1535 • ACR Convergence 2020
Frequency and Anatomic Distribution of Magnetic Resonance Imaging Lesions in the Sacro-iliac Joints of Healthy Subjects and Patients with Spondyloarthritis
Background/Purpose: Lesions detected by magnetic resonance imaging (MRI) of the sacroiliac joints are critical to the diagnosis of non-radiographic axial spondyloarthritis. However, some lesions, such…Abstract Number: 0964 • ACR Convergence 2020
Is Meniscal Status in the Anterior Cruciate Ligament Injured Knee Associated with Change in Bone Surface Area? An Exploratory Analysis of Data from the KANON Trial
Background/Purpose: Bone shape changes, which may be an important feature of osteoarthritis (OA) development, have been observed to occur early in the knee after anterior…Abstract Number: 1546 • ACR Convergence 2020
Ultrasound, Magnetic Resonance Imaging and Radiography of the Fingers’ Joints of Psoriatic Arthritis Patients
Background/Purpose: Ultrasound (US), magnetic resonance imaging (MRI) and conventional radiography are the leading imaging modalities for musculoskeletal (MSK) assessment in PsA. However, little is reported…Abstract Number: 1108 • ACR Convergence 2020
Cartilage Biomarkers s-Coll2-1 and s-Coll2-1NO2 Are Associated with Knee Osteoarthritis MRI Features and Predict Disease Worsening
Background/Purpose: To identify if biochemical markers s-Coll2-1, a peptide of type collagen and its nitrated from, s-Coll2-1NO2 are associated to knee osteoarthritis (OA), focusing on…Abstract Number: 1547 • ACR Convergence 2020
Role of Artificial Intelligence in Assessment of Peripheral Joint MRI in Inflammatory Arthritis: A Systematic Review and Meta-analysis
Background/Purpose: To summarize the feasibility, reliability, and validity of computer-aided quantification of joint destruction and synovitis on MRI using artificial intelligence (AI) based methods in…Abstract Number: 1113 • ACR Convergence 2020
Intrameniscal Signal Alterations Strongly Predict Destabilizing Meniscal Tears and Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Background/Purpose: It is unknown whether early changes in the menisci (e.g., intrameniscal signal alterations) have long-term consequences. We conducted a study to assess the prognostic…Abstract Number: 1557 • ACR Convergence 2020
Lymphatics as a Biomarker of Joint Physiology: Near-Infrared Imaging of Indocyanine Green Identifies Novel Routes of Lymphatic Drainage from Metacarpophalangeal Joints in Healthy Human Hands
Background/Purpose: In our previous work, we discovered that patients with active hand RA have reduced lymphatic drainage of indocyanine green (ICG) from the web spaces…Abstract Number: 1114 • ACR Convergence 2020
Longitudinally Assessed Structural Abnormalities on MRI and Relative Contributions to Risk of Incident Radiographic Knee Osteoarthritis over 10 Years of Follow-up
Background/Purpose: MRI has identified joint tissues affected during knee OA development, though the relative importance of structures in the pathogenic process is unknown. Our objective…Abstract Number: 1562 • ACR Convergence 2020
Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Clinical Remission Compared to Active Disease
Background/Purpose: Assessment of disease activity in psoriatic arthritis (PsA) is based on tender and swollen joint counts (TJC and SJC, respectively). Yet, the prevalence of…Abstract Number: 1115 • ACR Convergence 2020
The Relation of MRI-Based Cartilage Lesions to Knee Replacement and Knee Pain Severity in Osteoarthritis: The Multicenter Osteoarthritis Study
Background/Purpose: Recently, the FDA has indicated that data supporting imaging biomarkers of relevance to clinically important outcomes, such as knee replacement (KR) may be considered…
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