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Abstracts tagged "Magnetic resonance imaging (MRI)"

  • Abstract Number: 2213 • 2019 ACR/ARP Annual Meeting

    Evaluation of Factors Associated with Bone Structure in an SLE Cohort Measured by Clinical 3T MRI and DEXA

    Amit Saxena1, Peter Izmirly 2, Jill Buyon 2, Stephen Honig 2, Xiaoliu Zhang 3, Punam Saha 4, H. Michael Belmont 5 and Gregory Chang 2, 1New York University School of Medicine, New York, NY, 2NYU School of Medicine, New York, 3University of Iowa, Iowa City, 4University of Iowa Healthcare, Iowa City, 5New York University School of Medicine, Ney York

    Background/Purpose: Osteoporosis and bone fractures are a frequent cause of morbidity in systemic lupus erythematosus (SLE), and are felt to be related both to disease…
  • Abstract Number: 1173 • 2019 ACR/ARP Annual Meeting

    Magnetic Resonance Imaging in Patients in Clinical Remission: Tenosynovitis and Osteitis Are Independent Predictors of Radiographic and MRI Damage Progression

    Signe Møller-Bisgaard1, Kim Hørslev-Petersen 2, Bo Ejbjerg 3, Merete Lund Hetland 4, Lykke Midtbøll Ørnbjerg 1, Daniel Glinatsi 1, Jakob Møller 5, Mikael Boesen 6, Kristian Stengaard-Pedersen 7, Ole Rintek Madsen 8, Bente Jensen 9, Jan Alexander Villadsen 10, Ellen-Margrethe Hauge 7, Philip Bennett 11, Oliver Hendricks 12, Karsten Asmussen 9, Marcin Kowalski 13, Hanne Lindegaard 14, Henning Bliddal 15, Niels Steen Krogh 16, Torkell Ellingsen 17, Agnete Nielsen 18, Lone Balding 5, Anne Grethe Jurik 19, Henrik Thomsen 5 and Mikkel Østergaard 20, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, 2Department of Rheumatology, King Christian X’s Hospital for Rheumatic Diseases Graasten, Denmark, Graasten, Denmark, 3Department of Rheumatology, Zealand University Hospital, Køge, Denmark, Køge, Denmark, 4DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, 5Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark, 6Department of Radiology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, 7Department of Rheumatology, Department of Clinical Medicine, Aarhus University Hospital, Aarhus University, Aarhus, Denmark, Aarhus, Denmark, 8Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, 9Department of Rheumatology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, 10Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, 11Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte, Hellerup, Denmark, Copenhagen, Denmark, 12Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, Sønderborg, Denmark, 13Department of Rheumatology, Hjørring Hospital, Hjørring, Denmark, Hjørring, Denmark, 14Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, 15The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, 16Zitelab / DANBIO, Copenhagen, Denmark, 17Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark, 18Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, 19Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, 20Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark

    Background/Purpose: Progression of structural joint damage develops in 20-30 % of patients with rheumatoid arthritis (RA) in clinical remission1. Known predictors of structural damage progression…
  • Abstract Number: 2335 • 2019 ACR/ARP Annual Meeting

    Prediction of Myocardial Fibrosis in Rheumatoid Arthritis Assessed by Cardiac Magnetic Resonance Imaging Using Artificial Neural Networks Models

    Hitomi Kobayashi1, Isamu Yokoe 2, Yasuyuki Kobayashi 3, Eichi Takaya 4, Atsuma Nishiwaki 1, Kaita Sugiyama 1, Noboru Kitamura 1, Masaki Haraoka 3 and Masami Takei 1, 1Nihon University School of Medicine, Tokyo, Japan, 2Kyoundo Hospital, Tokyo, Japan, 3St.Marianna University School of Medicine, Kawasaki, Japan, 4Graduate School, Keio University, Tokyo, Japan

    Background/Purpose: Cardiac involvements cause of morbidity and mortality globally in rheumatoid arthritis (RA). Myocardial dysfunction may arise from a number of distinct processes, including myocardial…
  • Abstract Number: 1175 • 2019 ACR/ARP Annual Meeting

    Periarticular Inflammation and Bone Marrow Oedema Are Important in the Evaluation of Enthesitis on MRI in Patients with Peripheral and Axial SpA

    Xenofon Baraliakos1, Philipp Sewerin 2, Eugenio de Miguel 3, Christine Kleinmond 4, Ankita Shekhawat 5, Annette Wiedon 6 and Frank Behrens 7, 1Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, 2Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, 3Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, 4ClinProject GmbH, Eurasburg, Germany, 5Novartis Healthcare Pvt. Ltd., Hyderabad, India, 6Novartis Pharma GmbH, Nürnberg, Germany, 7CIRI/Rheumatology and Fraunhofer TMP, Goethe-University, Frankfurt, Germany

    Background/Purpose: Enthesitis is a hallmark feature of Spondyloarthritis (SpA), and frequently localizes at the Achilles tendon1. Enthesitis is predominantly measured with clinical scores like Leeds…
  • Abstract Number: 2728 • 2019 ACR/ARP Annual Meeting

    Efficacy and Safety of Upadacitinib in a Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 2/3 Clinical Study of Patients with Active Ankylosing Spondylitis

    Désirée van der Heijde1, In-Ho Song 2, Aileen Pangan 3, Atul Deodhar 4, Filip Van den Bosch 5, Walter P. Maksymowych 6, Tae-Hwan Kim 7, Mitsumasa Kishimoto 8, Andrea Everding 9, Yunxia Sui 10, Xin Wang 10, Alvina D. Chu 10 and Joachim Sieper 11, 1Leiden University Medical Center, Leiden, Netherlands, 2AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, 3AbbVie Inc., North Chicago, 4Oregon Health & Science University, Portland, OR, 5Ghent University Hospital, Ghent, Belgium, 6University of Alberta/CARE ARTHRITIS, Edmonton, AB, Canada, 7Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 8Immuno-Rheumatology Center, St. Luke’s International Hospital, Tokyo, Japan, 9HRF Hamburger Rheuma Forschungszentrum, Hamburg, Germany, 10AbbVie Inc., Chicago, 11Charité Universitätsmedizin Berlin, Germany, Berlin, Germany

    Background/Purpose: Patients (pts) with ankylosing spondylitis (AS) who have an inadequate response/contraindication to NSAIDs have limited treatment options other than biologics. The Janus kinase (JAK)…
  • Abstract Number: 1179 • 2019 ACR/ARP Annual Meeting

    Resting-State Functional Connectivity of Pain Processing Brain Region Associated with Therapeutic Response to Biologics in Rheumatoid Arthritis and Spondyloarthritis

    Nobuya Abe1, Yuichiro Fujieda 1, Kuniyuki Asou 1, Kohei Karino 2, Michihito Kono 3, Hisashi Narita 4, Masaru Kato 1, Khin Tha 5, Kenji Oku 1, Olga Amengual 1, Shinsuke Yasuda 1 and Tatsuya Atsumi 6, 1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 2Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 3Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, 4Department of Psychiatry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 5Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, 6Hokkaido University, Sapporo, Japan

    Background/Purpose: Background/Purpose: Discriminating inflammatory pain from non-inflammatory pain is critical to determine therapeutic strategy in inflammatory arthritis (IA) such as rheumatoid arthritis (RA) and spondyloarthritis…
  • Abstract Number: 2799 • 2019 ACR/ARP Annual Meeting

    Does Early Anterior Cruciate Ligament Reconstruction Prevent Further Meniscal Damage? Secondary Analysis of a Randomized Controlled Trial

    Barbara Snoeker 1, Frank Roemer 2, Aleksandra Turkiewicz 1, Stefan Lohmander 3, Richard Frobell 1 and Martin Englund1, 1Lund University, Lund, Sweden, 2University of Erlangen-Nuremberg, Erlangen, Germany, 3Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden, Lund, Sweden

    Background/Purpose: It has been suggested that recurrent instability episodes in a non-reconstructed anterior cruciate ligament (ACL) injured knee increase the risk for an incident meniscal…
  • Abstract Number: 1187 • 2019 ACR/ARP Annual Meeting

    Delayed Gadolinium-enhanced MR Imaging of Cartilage – A Pilot Study to Measure the Effect of Adalimumab Plus MTX versus Placebo Plus MTX on Cartilage in Early RA Patients (CAR-ERA-Study)

    Philipp Sewerin1, Miriam Frenken 2, Ralph Brinks 3, Christoph Schleich 2, Daniel Benjamin Abrar 2, Stefan Vordenbaeumen 4, Ruben Sengewein 5, Jutta Richter 6, Matthias Schneider 7 and Benedikt Ostendorf 4, 1Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, 2Institute for Diagnostic and Interventional Radiology, UKD, Heinrich Heine University, Duesseldorf, Germany, 3Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 4Policlinic and Hiller Research Unit of Rheumatology, UKD, Heinrich Heine University, Duesseldorf, Germany, 5Policlinic and Hiller Research Unit of Rheumatology,, Duesseldorf, Germany, 6Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, Nordrhein-Westfalen, Germany, 7Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany

    Background/Purpose: The purpose of this longitudinal study is to compare the effect of Adalimumab plus Methotrexate (MTX) versus MTX monotherapy on glycosaminoglycan content (GAG) in…
  • Abstract Number: 280 • 2019 ACR/ARP Annual Meeting

    Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial

    Ulf Sundin1, Anna-Birgitte Aga 2, Øivind Skare 3, Lena Nordberg 3, Till Uhlig 4, Hilde Hammer 3, Désirée van der Heijde 5, Tore Kvien 4, Siri Lillegraven 6 and Espen Haavardsholm 4, 1Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway. University of Oslo, Oslo, Norway, Oslo, Oslo, Norway, 2Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Oslo, Norway, 3Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway, 4Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway, 5Leiden University Medical Center, Leiden, Netherlands, 6Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway

    Background/Purpose: It has been debated whether treatment outcomes in early RA would be improved by targeting imaging remission, assessed by ultrasound or MRI, in addition…
  • Abstract Number: 1299 • 2019 ACR/ARP Annual Meeting

    Clinical Significance of Magnetic Resonance Imaging Derived Femur Bone Shape in Young Adults

    Minh-Tu Vo 1, Michael Bowes 2, Alison Venn 3, Flavia Cicuttini 4, Lyn March 5, Terence Dwyer 6, Tao Meng 3, Marita Cross 5, Graeme Jones 7, Saliu Balogun 1, Changhai Ding 7 and Benny Antony7, 1University of Tasmania, Hobart, Tasmania, Australia, 2Imorphics, Manchester, England, United Kingdom, 3University of Tasmania, Hobart, Australia, 4Monash University, Melbourne, Australia, 5University of Sydney, Sydney, Australia, 6University of Oxford, Oxford, United Kingdom, 7Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

    Background/Purpose: The femur bone shape derived from magnetic resonance imaging (MRI) of the knee is associated with the incidence and progression of knee osteoarthritis (OA),…
  • Abstract Number: 297 • 2019 ACR/ARP Annual Meeting

    Ultrasound and Magnetic Resonance Imaging Evaluation of the Fingers’ Joints of Psoriatic Arthritis Patients – Interim Analysis

    Ari Polachek1, Victoria Furer 2, Mirna Zureik 2, Sharon Nevo 2, Liran Mendel 2, David Levartovsky 3, Jonathan Wollman 4, Valerie Aloush 5, Mark Berman 6, Ilana Kaufman 6, Yael Lahat 2, Hagit Sarbagil-Maman 7, Sara Borok 6, Adi Broyde 6, Lihi Eder 8, Daphna Paran 1, Iris Eshed 9 and Ori Elkayam 10, 1Tel-Aviv Sourasky medical center, Tel Aviv, Israel, 2Sourasky Medical Center, Tel-Aviv, Israel, 3Sourasky medical center, Tel Aviv, Israel, 4Sourasky Medical Center, Herzelia, Israel, 5Tel Aviv Sourasky medical center, Tel Aviv, 6Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 7Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, 8Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada, 9Sheba Medical Center, Tel-Aviv, Israel, 10Rheumatology Department, Tel Aviv Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Israel., Tel Aviv, Israel

    Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory disease affecting up to 30% of psoriasis patients. PsA can involve both the peripheral and axial skeleton and…
  • Abstract Number: 1321 • 2019 ACR/ARP Annual Meeting

    What Is the Relationship Between the 3 Knee Bones in Osteoarthritis? Baseline and Longitudinal Associations Using a Latent Growth Modelling Approach on 37,583 MR Images from the Osteoarthritis Initiative

    Bright Dube1, Michael Bowes 2, Elizabeth Hensor 1, Sarah Kingsbury 3 and Philip G Conaghan 4, 1University of Leeds, LEEDS, England, United Kingdom, 2Imorphics, Manchester, England, United Kingdom, 3University of Leeds, Leeds, United Kingdom, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom

    Background/Purpose: 3D femur bone shape measured by statistical shape modelling (SSM) provides a responsive biomarker of knee OA. However it is unclear how the 3…
  • Abstract Number: 301 • 2019 ACR/ARP Annual Meeting

    PANLAR Ultrasound Study Group Recommendations for the Use of Imaging in the Management of Patients with Gout

    Marwin Gutierrez 1, Carlos Pineda 1, Janitzia Vazquez-Mellado 2, Mario Moreno Alvarez 3, Javier Rosa 4, Anthony Reginato5, Mario Chavez 6, Magaly Alva Linares 7, Marcelo Audisio 8, José Alexandre Mendonca 9, Tomas Cazenave 10, Oscar Sedano 11, Lucio Ventura Ríos 12, Eugenio de Miguel 13, Gurjit Kaeley 14, Eduardo Scheines 10, Fritz Hofmann 15, Gabriel Aguilar 16, Christian Waimann 17, Florencia Marengo 17 and Santiago Ruta 18, 1Division of Musculoskeletal and Rheumatic Diseases, Instituto Nacional de Rehabilitación “Luis Guillermo Ibarra Ibarra”, Mexico, Mexico, Mexico, 2Rheumatology Department, Hospital General de Mexico, Mexico, Mexico, 3Rheumatology Department, Hospital General Luis Vernaza, Guayaquil, Ecuador., Guayaquil, Ecuador, 4Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina, Buenos Aires, Argentina, 5Division of Rheumatology, Providence VAMC, Associate Professor in Medicine, The Warren Alpert School of Medicine, Providence, 6Universidad Autónoma de Aguascalientes Aguascalientes, México., Aguascalientes, Mexico, 7Rheumatology Department, Hospital Edgardo Rebagliati Martins, Lima, Peru., Lima, Peru, 8Rheumatology Department, Hospital Nacional de Clínicas, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Argentina., Cordoba, Argentina, 9Rheumatology Department, Pontifical Catholic University of Campinas, Brazil, Campinas, Brazil, 10Rheumatology Section, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, 11Reumatology Section, Hospital Marino Molina Scippa, Lima, Perú, Lima, Peru, 12Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", México, Mexico, Mexico, 13Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, 14Division of Rheumatology, University of Florida College of Medicine, Jacksonville, FL., Florida, 15Diagnostik Group, Puerto Vallarta, México., Puerto Vallarta, Mexico, 16Centro Diagnóstico Rossi, Buenos Aires, Argentina, Buenos Aires, Argentina, 17Rheumatology Unit, Hospital Dr. Héctor Cura, Olavarría, Argentina., Olavarria, Argentina, 18Rheumatology Department, Hospital San Martín de La Plata and Rheumatology Unit, Hospital Italiano de La Plata, Argentina., La Plata, Argentina

    Background/Purpose: Gout is a metabolic disease caused by deposition of monosodium urate (MSU) monohydrate crystals in different tissues. Imaging may be useful to evaluate the…
  • Abstract Number: 1506 • 2019 ACR/ARP Annual Meeting

    Long‑Term Certolizumab Pegol Treatment of Axial Spondyloarthritis Is Associated with Rapid and Sustained Reduction of Active Inflammation and Minimal Structural Changes in the Spine: 4‑Year MRI Results

    Xenofon Baraliakos1, Sebastian Kruse 2, Simone Auteri 3, Natasha de Peyrecave 4, Tommi Nurminen 5, Thomas Kumke 5, Bengt Hoepken 6 and Jürgen Braun 2, 1Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, 2Rheumazentrum Ruhrgebiet/Ruhr University, Herne, Germany, 3UCB Pharma, Brussels, Belgium, 4UCB Pharma, Slough, United Kingdom, 5UCB Pharma, Monheim, Germany, 6UCB Pharma, Monheim am Rhein, Germany

    Background/Purpose: Inflammation of the spine is believed to trigger a repair mechanism that results in syndesmophyte formation in axial spondyloarthritis (axSpA) patients (pts).1 Bone marrow…
  • Abstract Number: 505 • 2019 ACR/ARP Annual Meeting

    Low-grade Total Rheumatoid Arthritis MRI Scoring System Can Predict Successful Half-dose Reduction of MTX in Patients with RA in Clinical Remission

    Takeshi Suzuki1, Marina Uchida 2, Shoshi Shinagawa 2, Machiko Mizushima 3, Takayasu Ando 3, Yutaka Gotou 3, Tomohiko Shibata 2 and Kimito Kawahata 4, 1Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, 2Division of Rheumatology, Department of Internal Medicine, St. Marianna University School of Medicine, Yokohama City Seibu Hospital, Yokohama, Kanagawa, Japan, 3Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan, 4Rheumatology and Allergology, St. Marianna University School of Medicine, Tokyo, Japan

    Background/Purpose: It has been recommended that tapering csDMARDs should be considered if a patient is in persistent remission. However, methods for tapering csDMARDs, including MTX,…
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