2018 ACR/ARHP Annual Meeting Archives

Abstract Number: 124

M10, a Small Fragment of the Hepatocyte Growth Factor Receptor, Attenuates Fibrotic Changes in a Murine Model of Scleroderma Lung Disease and in Human Lung Fibroblasts
Abstract Number: 1876

Machine Learning Classification of Peripheral Blood Gene Expression Identifies a Subset of Patients with Systemic Sclerosis Most Likely to Show Clinical Improvement in Response to Hematopoietic Stem Cell Transplant
Abstract Number: 1007

Macrophage Mediators of Autoimmune Valvular Carditis and Fibrosis
Abstract Number: 1362

Magnetic Resonance Imaging Features Can Classify Adults Who Will Develop Accelerated Knee Osteoarthritis
Abstract Number: 2922

Magnetic Resonance Imaging of Sacroiliac Joints in Patients with Osteitis Condensans Ilii Reveals a Typical Pattern of Lesions Relevant for Differential Diagnosis with Axial Spondyloarthritis
Abstract Number: 311

Magnetic Resonance Imaging of the Cervical Spine in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis Presenting with Chronic Neck Pain – a Systematic Comparison of Clinical Assessments
Abstract Number: 2862

Magnitude of Response to TNF Inhibitors in Children with Spondyloarthritis and Sacroiliitis
Abstract Number: 2854

Majeed Syndrome Causing LPIN2 mutations May Prevent Bone “Healing” By Rendering M2 Macrophage Proinflammatory
Abstract Number: 2952

Major NSAID Toxicity: Derivation and Internal Validation of a Simple Clinical Risk Score
Abstract Number: 558

Major Reduction of Ultrasound Detected Synovitis during Subcutaneous Tocilizumab Treatment; Results from a Multicenter 24 Weeks Study of Patients with Rheumatoid Arthritis
Abstract Number: 2483

Major Secular Trends of Patient Characteristics and Inclusion Criteria in RA Clinical Trials
Abstract Number: 1524

Malignancies and Serious Infections in Randomized Controlled Trials of Janus Kinase Inhibitors in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
Abstract Number: 2991

Malignancies In Giant Cell Arteritis- A Population-Based Cohort Study
Abstract Number: 1515

Malignancy in Japanese Patients with Rheumatoid Arthritis Treated with Tofacitinib: Interim Analysis of All-Case Post-Marketing Surveillance
Abstract Number: 1595

Malignancy in Psoriatic Disease
Abstract Number: 162

Mammalian Target of Rapamycin (mTOR) Pathway Assessment in Antiphospholipid Antibody Positive Patients with Livedo Reticularis/racemosa
Abstract Number: 1913

Management of Ventricular Tachycardia and Cardiomyopathy in the Rheumatologist World: A Retrospective Review of Diagnostic Tools and Treatment Decisions for Cardiac Sarcoidosis
Abstract Number: PP03

Managing OsteoArthritis Pain with Daily Meditation
Abstract Number: 519

Marginal Structure Modeling of Association between Disease Activity and Hospitalized Infection Among Patients in a Rheumatoid Arthritis Registry
Abstract Number: 1895

Marked Immune Cell Subset Changes in Refractory Lupus Patients in a Phase I Trial of Allogenic Mesenchymal Stem Cells
Abstract Number: 1104

Mass Cytometry Analysis Detects Dysregulated T Cell Complement Responses in Diffuse Cutaneous Systemic Sclerosis
Abstract Number: 808

Mean Number of Nailfold Capillaries Is Associated with Disease Activity at 6 Months Follow-up in Systemic Sclerosis Patients
Abstract Number: 1536

Mean Platelet Volume Changes with Baricitinib Indicate Reduced New Platelet Production in Baricitinib-Treated Rheumatoid Arthritis Patients
Abstract Number: 2190

Means of Collaboration between Ophthalmologists, Rheumatologists and Internists in the Management of Non-Infectious Uveitis: A Nationwide Study
Abstract Number: 1469

Measurement of Anti-Amyloid β Autoantibodies in Patients with Rheumatoid Arthritis
Abstract Number: 2836

Measurement of Interferon Alpha Expression Using Multiple Methodologies Identifies a Signature in a Subgroup of Connective Tissue Disease Patients with Haematological Abnormalities
Abstract Number: 2282

Measurement of the Pro-Coagulant Activity of Microparticles in Patients with Inflammatory Rheumatic Diseases: Prospective Study
Abstract Number: 1991

Measuring Balance in an Experimental Mouse Model of Osteoarthritis
Abstract Number: 858

Measuring Cognitive Load during Arthrocentesis Training: Our Initial Experience
Abstract Number: 635

Measuring Spinal Mobility over Time in Early Axial Spondyloarthritis: Can We Do It Reliably?
Abstract Number: 1173

Measuring the Advanced Clinician Practitioner in Arthritis Care (ACPAC) Program Trained Extended Role Practitioner (ERP) Workforce in Canada: A Profile of Practice Settings, Roles and Participation in Models of Arthritis Care in Canada
Abstract Number: 203

Meat Consumption and Risk of Rheumatoid Arthritis in Women: A Population-Based Cohort Study
Abstract Number: 2594

Median Time to Pain Improvement in Patients with Psoriatic Arthritis Treated with Tofacitinib
Abstract Number: 828

Medium and Small-Sized Vessel Involvement in Hypereosinophilic Syndrome
Abstract Number: 719

Men and Sexual Function: An Overlooked Issue in Systemic Lupus Erythematosus
Abstract Number: 1846

Menarchal Status at Diagnosis and Final Height in Females with Childhood-Onset Systemic Lupus Erythematosus
Abstract Number: 146

Mesenchymal Stromal Cell Transferred Mitochondria Elicit an Immune Function Reprogramming That Entails T Regulatory Cell Commitment and Clinical Improvement of Graft Vs Host Disease
Abstract Number: 455

Metabolic Syndrome and Trajectories of Pain Severity and Number of Painful Sites in Knee Osteoarthritis: Data from a 10.7-Year Prospective Study
Abstract Number: 704

Metabolomics Analysis of Insulin Resistance in Mild/Inactive Non-Diabetic Systemic Lupus Erythematosus Women
Abstract Number: 1590

Metabolomics Profile Predicts Carotid Atherosclerosis Progression in Psoriatic Disease
Abstract Number: 2661

Metformin Combined with Conventional Therapy Increases Absolute Number of Regulatory T Cells in Patients with Systemic Lupus Erythematosus
Abstract Number: 122

Metformin Inhibited the Development of Bleomycin-Induced Murine Scleroderma Via Restoring the Balance between Regulatory and Effector T Cells and Suppressing Spleen Germinal Center Formation
Abstract Number: 2264

Methotrexate in the Treatment of Granulomatous Mastitis: A Retrospective Review of 19 Cases
Abstract Number: 2391

Methotrexate Polyglutamates As an Evaluation Tool for Appropriate Dosage of Oral Methotrexate Administration in Pediatric Patients
Abstract Number: 1245

Methotrexate Quality Improvement Project at UF Health Jacksonville Rheumatology Clinics
Abstract Number: 1492

Methotrexate Response in Early Rheumatoid Arthritis Predicted Using a Somamer Proteomic Assay
Abstract Number: 2814

Methotrexate Use and the Risk for Cardiovascular Disease Among Rheumatoid Patients Initiating Biologic Disease-Modifying Anti-Rheumatic Drugs
Abstract Number: 516

Microalbuminuria in Rheumatoid Arthritis: Investigating the Association with Diffuse Functional and Morphological Alterations of the Retinal Microvasculature, the Dermal Capillary Network and the Coronary Microcirculation
Abstract Number: 34

Microbiome-Drived Aberration of Hematopoietic Stem Cell Development Facilitates Immune Deregulation on the Onset of Collagen-Induced Arthritis in Mice
Abstract Number: 2018

Microenvironment Driven Re-Shaping of Pathogenic T Effector and Regulatory Subset in Active Juvenile Idiopathic Arthritic Patients
Abstract Number: 2839

Microrna Expression in the Vasculitic Skin Lesions of Adult Patients with IgA Vasculitis
Abstract Number: 1934

microRNA Targeting IL-33 Gene As Biomarker to Predict Subclinical Atherosclerosis in Patients with Early Rheumatoid Arthritis
Abstract Number: 1817

MicroRNA-128 Impairs Cartilage Integrity and Deteriorates Osteoarthritis Pathogenesis through Deregulating Chondrocyte Autophagy
Abstract Number: 2074

Micrornas Deregulation in Monocytes and T CD4 Lymphocytes from Patients with Axial Spondyloarthritis
Abstract Number: 2028

Microwave and Magnetic (M2) Myocardial Proteomics in the Mouse Model of Kawasaki Disease Demonstrates Normalization of the Proteome after Interleukin-1 Inhibition, Potential Novel Biomarkers, and Suggests New Insights into Mechanism of Disease
Abstract Number: 1449

Microwave Radiometry As a Novel Additional Method for Rheumatoid Arthritis Disease Activity Assessment: A Prospective Single-Center Study
Abstract Number: 261

Mindfulness Is Associated with Sleep Quality Among Patients with Fibromyalgia
Abstract Number: 2882

Minimal Progression of Disease Manifestation in Patients with Sjögren’s Syndrome Re-Evaluated Multiple Years after Initial Disease Classification
Abstract Number: 1468

Minor Salivary Gland Biopsy: Its Importance in Rheumatoid Arthritis and Secondary Sjögren’s Syndrom
Abstract Number: 2840

MiR-125-b Is a Promising Biomarker for Giant Cell Arteritis in Patients with Negative Temporal Artery Biopsy Examination
Abstract Number: 1025

MiR-146a a Key Player in Bone Metabolism
Abstract Number: 127

MiR-3606-3p Inhibits Systemic Sclerosis through Targeting TGF-β Receptor II
Abstract Number: 2272

Missed Opportunity? Evaluation for Systemic Autoimmune Diseases in Patients with Uveitis May Not be Optimal: 5-Year Analysis of Patients Being Seen in a Tertiary Medical Center
Abstract Number: 2931

Missing Outcomes in SLE Clinical Trials: Impact on Estimating Treatment Effects
Abstract Number: 1924

Mitigating Medication Risk Aversion in the Confident Treatment Decisions for Living with Rheumatoid Arthritis Trial
Abstract Number: 2250

Mitigation of Inflammation Induced By Monosodium Urate Crystals in Mice By Treatment with Svp-Rapamycin
Abstract Number: 2981

Mitochondrial Extrusion and Autoimmunity in Juvenile Dermatomyositis
Abstract Number: 776

MMP7 and CXCL12: Two Promising Biomarkers in Lupus Nephritis
Abstract Number: 1264

Modeling the Costs and Outcomes Associated with Treatment Sequences, with and without Tofacitinib, for Moderately to Severely Active Psoriatic Arthritis in the US
Abstract Number: 1538

Moderate Adverse Drug Reactions Due to Disease Modifying Drugs in a Cohort of Patients with Incident Rheumatoid Arthritis
Abstract Number: 742

Moderate to Severe Depression in Patients with Systemic Lupus Erythematosus
Abstract Number: 2134

Modifiable Risk Factors and the Development of Psoriatic Arthritis in People with Psoriasis
Abstract Number: 42

Modulation of Autoimmune Arthritis By Protein Tyrosine Phosphatase SHP-1
Abstract Number: 1903

Molecular Analysis of a Skin Equivalent Tissue Culture Model System of Systemic Sclerosis Using RNA Sequencing, Epigenetic Assays, Histology, and Immunoassays
Abstract Number: 151

Molecular Mechanisms of Pathogenic T Cell Resilience in Human Arthritis
Abstract Number: 2793

Molecular Mimicry and Autoimmunity: Anti-P. Gingivalis antibody Response in ACPA-Positive Rheumatoid Arthritis
Abstract Number: 22

Monoclonal Anti-Citrullinated Protein Antibodies Generated from RA-Derived B Cells Recognize Amino Acid Motifs Rather Than Specific Proteins
Abstract Number: 365

Monoclonal Gammopathy in Rheumatic Diseases
Abstract Number: 125

Monocyte Transcriptome Delineates SSc Patients with Functionally Distinct Patterns of Gene Dysregulation That Persist through Differentiation
Abstract Number: 2043

Monocytes and Macrophages of Patients with Rheumatoid Arthritis Respond to Pathologically Increased Ionized Calcium with Proinflammatory Cytokine Production
Abstract Number: 1009

Monocytes Membrane TNF Expression and Anti-TNF Treatment in Rheumatoid Arthritis
Abstract Number: 2235

Monosodium Urate Deposition Distribution in the Knees, Hands, and Feet of Treated Gout Patients: A Dual-Energy CT Study
Abstract Number: 2097

Monotherapy with Filgotinib, a JAK1-Selective Inhibitor, Reduces Disease Severity and Alters Immune Cell Subsets in the NZB/W F1 Murine Model of Lupus
Abstract Number: 1171

Mortality Among Those with OA: Time-Varying Effects of Socioeconomic Measures
Abstract Number: 212

Mortality and Causes of Death in Patients with Inflammatory Arthritis in Hong Kong over 20 Years
Abstract Number: 2136

Mortality Rates and Causes in Psoriatic Arthritis Patients
Abstract Number: 1331

Moving from Dermatomyositis Associated with Anti-Melanoma Differentiation-Associated Gene 5 Antibody to Anti-Melanoma Differentiation-Associated Gene 5 Syndrome
Abstract Number: 1445

MRI Bone Erosions in RA Patients Relatives with Clinically Suspicious Arthralgia
Abstract Number: 654

MRI Lesion Definitions in Axial Spondyloarthritis: A Consensus Reappraisal from the Assessments in Spondyloarthritis International Society
Abstract Number: 1819

MUC5B promoter Variant rs35705950 Is a Risk Factor for Rheumatoid Arthritis – Interstitial Lung Disease
Abstract Number: 1789

Mucocutaneous Activity Index As a Patient-Reported Outcome Measure in Behcet’s Disease: A Multi-Center Study from Turkey
Abstract Number: 2091

Mucosal-Associated Invariant T (MAIT) Cells As a Potential Therapeutic Target for Systemic Lupus Erythematosus
Abstract Number: 2784

Multi Modal Imaging Algorithm to Improve the Accuracy for the Diagnosis of Giant Cell Arteritis
Abstract Number: 609

Multi-Biologic Usage in Rheumatoid Arthritis Is Not Infrequent in the Routine Practice
Abstract Number: 921

Multi-Omics Analysis Identifies a Gene Signature Associated with the Clinical Response to Anti-TNF Therapy in Rheumatoid Arthritis
Abstract Number: 1102

Multi-Organ RNA-Sequencing of Patients with Systemic Sclerosis (SSc) Finds That Intrinsic Subsets Are Conserved across Organ Systems
Abstract Number: 2958

Multi-Site Study Evaluating Performance on Lupus Nephritis Quality Measures
Abstract Number: 2972

Multicentric Reticulohistiocytosis (1980-2017): A Rare Disease, Commonly Associated with Malignancy and Autoimmunity
Abstract Number: 2611

Multidrug Resistant AxSpA: No Advantage of Switching Class in Patients with Inadequate Response to Two Prior TNFi Agents
Abstract Number: 2320

Multimorbidity Is Associated with Hip Fractures in Both Women and Men and across Different Races
Abstract Number: 2033

Multiparameter Mass Cytometry By Time-of-Flight Spectrometry (CyTOF) Phenotyping in Pediatric Localized Scleroderma
Abstract Number: 1935

Multiple Dose Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP5094, an Anti-Alpha9 Integrin Monoclonal Antibody, in Patients with Rheumatoid Arthritis on Methotrexate
Abstract Number: 2832

Multiple Subpopulations of Peripheral Lymphocytes Were Absolutely Decreased in SLE Patients with Infection and Restored By Low-Dose IL-2
Abstract Number: 2917

Multiplex Serum Biomarker Analysis before and during Therapy with Canakinumab in Patients with Systemic Juvenile Idiopathic Arthritis
Abstract Number: 1737

Multiplexed Autoantibody Profiles in a Systemic Sclerosis Clinical Trial Comparing Autologous Hematopoietic Stem Cell Transplantation and Cyclophosphamide
Abstract Number: 2006

Murine Ear Wound Cartilage Superhealer Trait Is Associated with Gut Microbiota Changes and Is Transferable to Non-Healer Mice By Gut Microbiome Transplant
Abstract Number: 381

Muscle Endurance Deficits in Myositis Patients Despite Normal Manual Muscle Testing Scores
Abstract Number: 398

Muscle Function and Health-Related Quality of Life in Patients with Polymyositis and Dermatomyositis
Abstract Number: 399

Musculoskeletal Comorbidities after Total Knee Replacement for Osteoarthritis
Abstract Number: 357

Musculoskeletal Immune-Related Adverse Events with Use of Checkpoint Inhibitors in Malignancy: Experience in Sydney, Australia
Abstract Number: 1652

Musculoskeletal Involvement in Inflammatory Bowel Disease’S Patients: A Mono Centric Experience
Abstract Number: 2260

Musculoskeletal Sarcoidosis: A 15-Year Experience from a Tertiary Care Center in the US
Abstract Number: 1205

Musculoskeletal Ultrasound and Conventional Radiography Evaluation of the Hip in Patients with Calcium Pyrophosphate Deposition Disease
Abstract Number: 1983

Mutations Associated with Clonal Hematopoiesis of Indeterminate Potential Are Found in Peripheral Blood and Synovial Fluid Macrophages from Patients with Rheumatoid and Psoriatic Arthritis
Abstract Number: 1820

Myeloablative Autologous Hematopoietic Stem Cell Transplantation for Severe Scleroderma: Long-Term Outcomes 6-11 Years after Entry on a Randomized Study Comparing Transplantation and Cyclophosphamide
Abstract Number: 1337

Myocardial Fatty Acid Metabolism and Perfusion Mismatch in Scintigraphy Predicts Worse Prognosis in Clinically Amyopathic Dermatomyositis
Abstract Number: 1612

Myocardial Infarctions Among Ankylosing Spondylitis Patients in a Large US Insurance Database
Abstract Number: 2934

Myocardial Microscopic Fibrosis Assessed By T1 Mapping Sequences on Cardiac Magnetic Resonance Imaging Predicts Cardiac Events in Systemic Sclerosis: Data from a Prospective Cohort Study on 40 Patients
Abstract Number: 131

Myofibroblast Cells Expression of CD248 May Contribute to Exacerbate Microvascular Damage during Systemic Sclerosis
Abstract Number: 2286

Myositis and Fasciitis By Magnetic Resonance Imaging in Recent-Onset Polymyalgia Rheumatica and Effect of Tocilizumab Therapy
Abstract Number: 383

Myositis Patients with Anti-U1-RNP and Anti-Ro52 Autoantibodies Are at Risk of Pericarditis, Glomerulonephritis, and Pulmonary Hypertension
Abstract Number: 1339

Myositis Specific Anti-Histidyl tRNA Synthetase (HisRS) Autoantibodies Display High Reactivity Against Hisrs Conformational Epitopes and Associate with Lung and Joint Involvement
Abstract Number: 1342

Myositis Specific Antibodies Measured Using a Novel Particle Based Multi-Analyte Assay Resemble Myositis Subsets By Principle Component Analysis
Abstract Number: 397

Myositis-Specific Autoantibodies and Their Clinical Associations