Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 591 • 2019 ACR/ARP Annual Meeting
Longitudinal Assessment of MRI of the Sacroiliac Joints in the ASAS Classification Cohort: Evolution of Diagnostic Features and Predictive Utility for Axial Spondyloarthritis
Walter P. Maksymowych¹, Xenofon Baraliakos ², Manouk de Hooge ³, Iris Eshed ⁴, Susanne Juhl Pedersen ⁵, Ulrich Weber ⁶, Joachim Sieper ⁷, Stephanie Wichuk ⁸, Denis Poddubnyy ⁹, Martin Rudwaleit ¹⁰, Désirée van der Heijde ¹¹, Robert B.M. Landewé ¹², Joel Paschke ¹³, Robert Lambert ⁸ and Mikkel Østergaard ¹⁴, ¹University of Alberta/CARE ARTHRITIS, Edmonton, AB, Canada, ²Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ³Ghent University Hospital, Ghent, Belgium, ⁴Sheba Medical Center, Tel Aviv, Israel, ⁵Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, ⁶Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Sonderborg, Denmark, ⁷Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ⁸University of Alberta, Edmonton, Canada, ⁹Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ¹⁰Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ¹¹Leiden University Medical Center, Leiden, Netherlands, ¹²Amsterdam University Medical Center, Amsterdam, Netherlands, ¹³CARE Arthritis, Edmonton, Canada, ¹⁴Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Follow up of the ASAS Classification Cohort (CC) indicated a high positive predictive value for the ASAS classification criteria derived from baseline patient and…
Abstract Number: 1738 • 2019 ACR/ARP Annual Meeting
Tracking Whole-Brain Volumetric Trends in Childhood-onset Systemic Lupus Erythematosus Patients in the Clinical Setting by Magnetic Resonance Imaging
Hermine Brunner¹, Arjun Mathur ², William O'Brien ³ and Mark DiFrancesco ³, ¹Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ²Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: The course of childhood-onset Systemic Lupus Erythematosus (cSLE) commonly includes neurocognitive dysfunction, a manifestation with poor prognosis. It has been challenging to diagnose and…
Abstract Number: 851 • 2019 ACR/ARP Annual Meeting
Association Between Bone Marrow Edema and Structural Progression in the Same Quadrant in Axial Spondyloarthritis – 5-year Data from the DESIR Cohort
Santiago Rodrigues-Manica¹, Alexandre Sepriano ², Sofia Ramiro ³, Robert B.M. Landewé ⁴, Pascal Claudepierre ⁵, Anna Molto ⁶, Maxime Dougados ⁷, Miranda van Lunteren ² and Désirée van der Heijde ², ¹CEDOC, NOVA-Medical School | Hospital Egas Moniz, CHLO, Lisbon, Lisbon, Portugal, ²Leiden University Medical Center, Leiden, Netherlands, ³Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands, ⁴Amsterdam University Medical Center, Amsterdam, Netherlands, ⁵Rheumatology, CHU Henri Mondor Créteil, Paris, France, ⁶Paris Descartes University, Medicine Faculty; APHP, Rheumatology, Hôpital Cochin, Hôpitaux de Paris, Paris, Paris, France, ⁷Cochin Hospital, Paris, France
Background/Purpose: The overall presence of inflammation in the MRI-SIJ is associated with overall 5-year radiographic damage in patients with axSpA. But we do not know…
Abstract Number: 1823 • 2019 ACR/ARP Annual Meeting
Magnetic Resonance Enterography as a Screening Tool to Detect Sacroiliitis in Crohn’s Disease: Association with Clinical and Endoscopic Markers of Crohn’s Disease Activity
Fardina Malik¹, Irvine Levine ², Gabrielle Castillo ¹, Brian Jaros ², Erin Alaia ¹, Justin Ream ², Jordan E. Axelrad ¹, David P. Hudesman ¹ and Jose Scher ³, ¹New York University School of Medicine, New York, NY, ²New York University School of Medicine, New York, ³Division of Rheumatology, New York University School of Medicine and NYU Langone Orthopedic Hospital, New York, NY
Background/Purpose: Prevalence of sacroiliitis (SI) in Crohn’s disease (CD) varies widely (range 4% -39%), depending on criteria utilized to define the disease (e.g. inflammatory back…
Abstract Number: 856 • 2019 ACR/ARP Annual Meeting
MRI of the Sacroiliac Joints in Athletes: Do Semi-axial Slices Added to Standard Semi-coronal Scans Facilitate Recognition of Non-specific Bone Marrow Edema?
Ulrich Weber¹, Anne Grethe Jurik ², Anna Zejden ², Ejnar Larsen ³, Steen Hylgaard Jørgensen ⁴, Kaspar Rufibach ⁵, Christian Schioldan ⁶ and Søren Schmidt-Olsen ⁷, ¹Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Sonderborg, Denmark, ²Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ³Department of Radiology, North Denmark Regional Hospital, Hjørring, Denmark, ⁴Center for Clinical Research, North Denmark Regional Hospital, Hjørring, Denmark, ⁵Division of Biostatistics, F. Hoffmann-La Roche, Basel, Switzerland, ⁶Department of Physiotherapy, Clinic Benefit, Frederikshavn, Denmark, ⁷Department of Rheumatology and Sports Medicine, North Denmark Regional Hospital, Hjørring, Denmark
Background/Purpose: Low grade bone marrow edema (BME) on magnetic resonance imaging (MRI) of the sacroiliac joints (SIJ) is challenging the discrimination between patients with early…
Abstract Number: 1854 • 2019 ACR/ARP Annual Meeting
The Utility of Fat Lesions in Close Relation to Other Structural MRI Lesions in the Sacroiliac Joints for Diagnosing Patients with Axial Spondyloarthritis
Sengül Seven¹, Mikkel Østergaard ², Lone Morsel-Carlsen ³, inge Juul Sørensen ¹, Birthe Bonde ⁴, Gorm Thamsborg ⁵, Jens Jørgen Lykkegaard ¹, Oliver Hendricks ⁶, Niklas Rye Jørgensen ⁷ and Susanne Juhl Pedersen ⁸, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, ²Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, ³Department of Radiology, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, ⁴The Birthe Bonde Clinic of Physioterapy, Copenhagen, Denmark, Glostrup, Denmark, ⁵Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, ⁶Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, Sønderborg, Denmark, ⁷Department of Clinical Biochemistry, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, ⁸Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark
Background/Purpose: Bone marrow edema on MRI of the sacroiliac joints (SIJ) plays an important role in the ASAS (Assessment of Spondyloarthritis International Society) classification criteria…
Abstract Number: 987 • 2019 ACR/ARP Annual Meeting
Anti-citrullinated Protein Antibodies Induce Subclinical Inflammation, Bone Loss and Pain in Mice
Akilan Krishnamurthy¹, Yogan Kisten ², Alexandra Circiumaru ³, Katalin Sandor ⁴, Koji Sakurabas ⁵, Gustaf Wigerblad ⁶, Peter Damberg ⁷, Heidi Wähämaa ³, Patrik Jarvolli ⁷, Vivianne Malmström ⁸, Lars Klareskog ⁹, Camilla I Svensson ¹⁰, Juan Jimenez Jimenez Andrade ¹¹, Bence Rethi ³ and Anca Catrina ⁹, ¹Rheumatology unit, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Solna, Stockholm, ²Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, Stockholms Lan, Sweden, ³Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, ⁴Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden, stockholm, Sweden, ⁵Rheumatology unit, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Solna, stockholm, Sweden, ⁶karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden, ⁷Karolinska Institutet, Karolinska Experimental Research and Imaging Centre (KERIC), stockholm, Sweden, stockholm, Sweden, ⁸Rheumatology Unit, Department of Medicine, Karolinska University Hospital and Institutet, Stockholm, Sweden., Stockholm, Sweden, ⁹Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden, ¹⁰Karolinska Institutet, Physiology and Pharmacology, stockholm, Sweden, Stockholm, Sweden, ¹¹Universidad Autónoma de Tamaulipas, Reynosa, Tamaulipas, Mexico, Tamaulipas, Mexico
Background/Purpose: Autoantibodies against citrullinated proteins (ACPAs) could be associated with bone loss, pain and tenosynovitis prior to disease onset in human rheumatoid arthritis (RA) and…
Abstract Number: 2019 • 2019 ACR/ARP Annual Meeting
Tenosynovitis at the Metatarsophalangeal Joints, a Novel Feature of RA: Results from an Anatomical and Large Magnetic Resonance Imaging Study of Tendon Sheaths of the Forefoot
Yousra Dakkak¹, Friso Jansen ¹, Marco DeRuiter ¹, Monique Reijnierse ¹ and Annette van der Helm-van Mil ², ¹Leiden University Medical Center, Leiden, Netherlands, ²LUMC, Leiden, Zuid-Holland, Netherlands
Background/Purpose: Recent magnetic resonance imaging (MRI)-studies revealed that tenosynovitis in the hands is associated with rheumatoid arthritis (RA). Although the forefoot is a preferential location…
Abstract Number: 1162 • 2019 ACR/ARP Annual Meeting
Changes in Novel Composite Scores of Disease Activity and Cumulative Damage Are Prognostic of Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Matthew Harkey¹, Julie Davis ², Bing Lu ³, Lori Lyn Price ⁴, Robert Ward ⁵, James MacKay ⁶, Charles Eaton ⁷, Grace Lo ⁸, Mary Barbe ⁹, Ming Zhang ⁵, Jincheng Pang ¹⁰, Alina Stout ¹¹, Lavalley Michael ¹², Timothy McAlindon ¹³ and Jeffrey Driban ¹³, ¹University of Massachusetts Medical School, Worcester, ²George Washington University, Washington DC, ³Brigham and Women's Hospital, Boston, MA, ⁴Tufts Medical Center, Tufts University, Boston, MA, ⁵Tufts Medical Center, Boston, ⁶University of Cambridge, Cambridge, United Kingdom, ⁷Brown University Center for Primary Care and Prevention, Pawtucket, ⁸Center of Excellence Michael E. DeBakey VAMC, Baylor College of Medicine, Houston, TX, ⁹Temple University, Philadelphia, ¹⁰Pfizer, Inc., Cambridge, MA, ¹¹Northeastern University, Boston, ¹²Boston University, Boston, ¹³Tufts Medical Center, Boston, MA
Background/Purpose: Composite imaging scores that reflect cartilage damage, bone marrow lesions (BMLs), and effusion-synovitis may enable us to conceptualize knee osteoarthritis (KOA) disease progression as…
Abstract Number: 2185 • 2019 ACR/ARP Annual Meeting
MRI-detected Abnormalities in Prediction Models of Incident Radiographic Knee Osteoarthritis over 10 Years of Follow-up
C. Kent Kwoh¹, Frank Roemer ², Erin Ashbeck ³, ChengCheng Hu ¹, Edward Bedrick ¹, Leena Sharma ⁴ and Ali Guermazi ⁵, ¹University of Arizona, Tucson, AZ, ²University of Erlangen-Nuremberg, Erlangen, Germany, ³The University of Arizona Arthritis Center, University of Arizona, Tuccson, AZ, Tucson, AL, ⁴Northwestern University, Chicago, IL, ⁵Boston Medical Center, Boston
Background/Purpose: MRI Osteoarthritis Knee Score (MOAKS) is a semi-quantitative scoring system used to assess MRI-detected structural abnormalities including over 100 raw scores representing multiple joint…
Abstract Number: 1163 • 2019 ACR/ARP Annual Meeting
Erosions Are the Most Often Reported Structural Lesion on MRI of the Sacroiliac Joints in axSpA Patients with IBP
Manouk de Hooge¹, Ann-Sophie De Craemer ¹, Thomas Renson ¹, Philippe Carron ¹, Liselotte Deroo ¹, Dirk Elewaut ¹ and Filip Van den Bosch ¹, ¹Ghent University Hospital, Ghent, Belgium
Background/Purpose: HLA-B27 and sacroiliitis on MRI form the basis of the Assessment of SpondyloArthritis international Society (ASAS) axial spondyloarthritis (axSpA) classification criteria. In addition, while…
Abstract Number: 2190 • 2019 ACR/ARP Annual Meeting
Multi-vendor Multi-site T1ρ and T2 Quantification of Knee Cartilage
Jeehun Kim ¹, Kenji Mamoto ², Richard Lartey ¹, Kaipin Xu ¹, Matthew Tanaka ³, Emma Bahroos ³, Carl Winalski ², Thomas Link ³, Peter Hardy ⁴, Qi Peng ⁵, Angie Botto-van Bemden ⁶, Kecheng Liu ⁷, Robert Peters ⁸, Can Wu ⁹ and Xiaojuan Li¹⁰, ¹Program of Advanced Musculoskeletal Imaging, Cleveland Clinic Foundation, Cleveland, ²Cleveland Clinic Foundation, Cleveland, ³University of California, San Francisco, San Francisco, ⁴University of Kentucky, Lexington, ⁵Albert Einstein College of Medicine, New York City, ⁶Arthritis Foundation, Atlanta, ⁷Siemens Medical Solution Inc, Malvern, ⁸GE Healthcare, Milwaukee, ⁹Philips Healthcare, Andover, ¹⁰Program of Advanced Musculoskeletal Imaging, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Osteoarthritis (OA) is a degenerative joint disease characterized by deterioration of articular cartilage in the joints. MRI T1ρ and T2 relaxation times have been…
Abstract Number: 1164 • 2019 ACR/ARP Annual Meeting
Novel Computer Assisted Methodology for Quantitative Assessment of MRI Treatment Responses to Apremilast in Patients with Psoriatic Arthritis
Paul Bird ¹, Mikael Boesen ², Mark Hinton ³, Eser Sanverdi ³, Romiesa Hagoug ³, Chrisotpher Sabin ³, Priscila Nakasato ⁴, Benoit Guerette ⁴ and Olga Kubassova⁵, ¹Optimus Research, Kogarah, New South Wales, Australia, ²Dept. of Radiology, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, ³Image Analysis Ltd, London, United Kingdom, ⁴Celgene Corporation, Summit, ⁵Image Analysis Group, London, United Kingdom
Background/Purpose: Response to treatment in Psoriatic Arthritis (PsA) can be captured using the OMERACT PsA Magnetic Resonance Imaging Score (PsAMRIS). While reliable and valid, PsAMRIS…
Abstract Number: 2196 • 2019 ACR/ARP Annual Meeting
Machine Learning Defines the Relationship Between Structural Knee Osteoarthritis and Patient-Important Outcomes: An 8-year Study of 47,858 Knee MRIs from the Osteoarthritis Initiative (OAI)
Michael Bowes¹, Katherine Kacena ², Oras Alabas ³, Alan Brett ¹, Bright Dube ⁴, Neil Bodick ⁵ and Philip G Conaghan ⁶, ¹Imorphics, Manchester, England, United Kingdom, ²BioBridges, Wellesley Hills, ³Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ⁴University of Leeds, LEEDS, England, United Kingdom, ⁵Flexion Therapeutics, Burlington, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom
Background/Purpose: Osteoarthritis (OA) is a slowly progressing disease which may be asymptomatic for many years. Therapy development has been hampered by poor understanding of both…
Abstract Number: 1171 • 2019 ACR/ARP Annual Meeting
Evidence of Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Minimal Disease Activity – Interim Analysis
Victoria Furer¹, Ari Polachek ², Liran Mendel ¹, David Levartovsky ³, Jonathan Wollman ⁴, Valerie Aloush ⁵, Ilana Kaufman ⁶, Hagit Sarbagil-Maman ⁷, Sara Borok ⁶, Mark Berman ⁶, Adi Broyde ⁶, Yael Lahat ¹, Mirna Zureik ¹, Sharon Nevo ¹, Daphna Paran ⁶, Iris Eshed ⁸ and Ori Elkayam ⁶, ¹Sourasky Medical Center, Tel-Aviv, Israel, ²Tel-Aviv Sourasky medical center, Tel Aviv, Israel, ³Sourasky medical center, Tel Aviv, Israel, ⁴Sourasky Medical Center, Herzelia, Israel, ⁵Tel Aviv Sourasky medical center, Tel Aviv, ⁶Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁷Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, ⁸Sheba Medical Center, Tel Aviv, Israel
Background/Purpose: Subclinical inflammatory lesions detected by MRI are prevalent in hand joints of patients with cutaneous psoriasis (1). Yet, it is unknown whether these inflammatory…

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