Abstracts Archive - Page 1408 of 2425 - ACR Meeting Abstracts

Abstract Number: 16 • 2017 Pediatric Rheumatology Symposium
Novel Serum Broad-Based Proteomic Discovery Analysis Identifies Proteins and Pathways Dysregulated in Juvenile Dermatomyositis (JDM) Myositis Autoantibody Groups
Hanna Kim¹, Angélique Biancotto², Foo Cheung³, Terrance P. O'Hanlon⁴, Ira N. Targoff⁵, Yan Huang⁶, Frederick Miller⁴, Raphaela Goldbach-Mansky⁶ and Lisa G. Rider⁴, ¹Pediatric Translational Research Branch, NIAMS/NIH, Bethesda, MD, ²Center for Human Immunology, Autoimmunity and Inflammation (CHI), NHLBI, NIH, Bethesda, MD, ³Center for Human Immunology Autoimmunity and Inflammation (CHI), NHLBI, NIH, Bethesda, MD, ⁴Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, ⁵VA Medical Center, University of Oklahoma Health Sciences Center, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Translational Autoinflammatory Disease Studies (TADS), NIAID, NIH, Bethesda, MD
Background/Purpose: Juvenile dermatomyositis (JDM) is a complex heterogeneous autoimmune disease. Myositis-specific autoantibodies (MSAs), present in up to 80% of JDM patients, help define distinct phenotypes…
Abstract Number: 139 • 2017 Pediatric Rheumatology Symposium
Dysregulation of miRNA in mononuclear cells of patients with enthesitis related arthritis
Amita Aggarwal¹ and Sushma Singh², ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Background/Purpose: Enthesitis related arthritis (ERA) is the most common category of JIA in Asia. Identifying dysregulated microRNA may help in understanding the pathogenesis of ERA.…
Abstract Number: 17 • 2017 Pediatric Rheumatology Symposium
Anti-endothelial cell antibodies in juvenile dermatomyositis
Rie Karasawa¹, Mayumi Tamaki¹, Toshiko Sato¹, Megumi Tanaka¹, Kazuo Yudoh² and James Jarvis³, ¹Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, ²Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan, ³Pediatrics, SUNY Buffalo School of Medicine, Buffalo, NY
Background/Purpose: Juvenile dermatomyositis (JDM) is the most common form of inflammatory myopathy in children. Although classified as a myopathy, involved tissues in JDM are characterized…
Abstract Number: 38 • 2017 Pediatric Rheumatology Symposium
Knowledge Translation in Juvenile Idiopathic Arthritis Research in Canada: A Focus on Pediatric Rheumatologists and Allied Health Professionals
Benjamin Rose-Davis¹, Janet Curran², Tania Cellucci³, Ciarán M. Duffy⁴, Lori Tucker^5,6, Michelle Batthish⁷, Adam Huber⁸, Bianca Lang^9,10, Deborah M. Levy¹¹, Dax Rumsey¹², Karen N Watanabe Duffy¹³ and Elizabeth Stringer¹⁴, ¹Division of Pediatric Rheumatology, IWK Health Centre, Halifax, NS, Canada, ²Department of Pediatrics, IWK Health Centre, Halifax, NS, Canada, ³Pediatrics/Rheumatology, McMaster Children's Hospital, Hamilton, ON, Canada, ⁴Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁵Rheumatology, BC Childrens Hospital, Vancouver, BC, Canada, ⁶Pediatric Rheum/Rm K4-120, BC Childrens Hospital, Vancouver, BC, Canada, ⁷Division of Pediatric Rheumatology, McMaster Children's Hospital, Hamilton, ON, Canada, ⁸IWK Health Centre, Halifax, NS, Canada, ⁹Pediatrics, IWK Health Centre, Halifax, NS, Canada, ¹⁰Rheumatology, IWK Health Centre, Halifax, NS, Canada, ¹¹Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹²Stollery Children's Hospital, Edmonton, AB, Canada, ¹³Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹⁴Department of Rheumatology, IWK Health Centre, Halifax, NS, Canada
Background/Purpose: Knowledge Translation (KT) is an iterative process that includes synthesis, dissemination, and application of knowledge to improve health. The aim of this study is…
Abstract Number: 118 • 2017 Pediatric Rheumatology Symposium
Oxygen Saturation Recordings in Pediatric Rheumatology Patients At Risk For Lung Disease
Rebecca Trachtman¹, Alexa Adams², Nancy Pan², Sarah Taber² and Karen Onel², ¹Pediatric Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, NY, NY, ²Pediatric Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY
Background/Purpose: Pediatric rheumatology patients are at high risk for the development of pulmonary disease. Lung disease in these patients can go unnoticed for long periods…
Abstract Number: 94 • 2017 Pediatric Rheumatology Symposium
Effects of Age and Gender on Reference Levels of Biomarkers Comprising the Pediatric Renal Activity Index for Lupus Nephritis (p-RAIL)
Michael Bennett¹, Qing Ma², Jun Ying³, Prasad Devarajan¹ and Hermine Brunner⁴, ¹Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Dept of Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Center for Biostatistical Services, University of Cincinnati College of Medicine, Cincinnati, OH, ⁴Rheumatology, PRCSG, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease that disproportionately effects women and children of minorities. Renal Involvement (lupus nephritis, or LN) with…
Abstract Number: 75 • 2017 Pediatric Rheumatology Symposium
Ferritin:ESR, A Predictor of MAS?
Miriah Gillispie¹, Marietta DeGuzman², Mark Gorelik³ and Tiphanie Vogel^4,5, ¹Pediatrics, Department of IAR, Baylor College of Medicine, Houston, TX, ²Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ³Baylor College of Medicine, San Antonio, TX, ⁴Department of Pediatrics, Division of Immunology, Allergy and Rheumatology and the Center for Human Immunology at Texas Children's Hospital., Baylor College of Medicine, Houston, TX, ⁵Center for Human Immunobiology, Texas Children's Hospital, Houston, TX
Background/Purpose: Systemic onset juvenile idiopathic arthritis (SoJIA) is a rare autoinflammatory disorder comprising only 10% of JIA. Macrophage activation syndrome (MAS), an excessive and uncontrolled…
Abstract Number: 158 • 2017 Pediatric Rheumatology Symposium
Quality of Referral Letters to Pediatric Rheumatology and Its Impact on Access to Care
Alexandra Rydz^1,2, Fangfang Fu³, Mark Drew¹, Dax Rumsey^1,2, Yan Yuan¹ and Mercedes Chan^1,2, ¹University of Alberta, Edmonton, AB, Canada, ²Stollery Children's Hospital, Edmonton, AB, Canada, ³Mathematical and Statistical Science, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Delays in access to care in pediatric rheumatology (PR) are well known and may lead to significant morbidity. While barriers in accessing PR care…
Abstract Number: 70 • 2017 Pediatric Rheumatology Symposium
Impact of Systemic Juvenile Idiopathic Arthritis/Still’s Disease on Adolescents as Evidenced Through Social Media Posting
Renee F Modica¹, Kathleen G Lomax², Pamela Batzel³, Armelle Cassanas³ and Melissa E Elder¹, ¹Department of Pediatrics, University of Florida, Gainesville, FL, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ, ³Treato, Princeton, NJ
Background/Purpose: Systemic juvenile idiopathic arthritis (SJIA)/Still’s disease is a rare form of chronic arthritis in pediatrics. The patient perspective of living with the disease is…
Abstract Number: 86 • 2017 Pediatric Rheumatology Symposium
The myositis-specific autoantibody and myositis-associated autoantibody phenotypes in Japanese juvenile idiopathic inflammatory myopathies
Takako Miyamae, Takayuki Kishi and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan
Background/Purpose: Demographics,clinical features,and outcomes among myositis-specific autoantibody (MSA) and myositis-associated autoantibodies (MAAs) subgroups were assessed in children with juvenile idiopathic inflammatory myopathies (JIIM). Methods: MSAs…
Abstract Number: 69 • 2017 Pediatric Rheumatology Symposium
The Disease Burden of Systemic Juvenile Idiopathic Arthritis for Patients and Caregivers: An International Health Related Quality of Life Survey and Retrospective Chart Review
Susan Shenoi¹, Gerd Horneff², Michal Cidon³, Athimalaipet Ramanan⁴, Yukiko Kimura⁵, Pierre Quartier⁶, Ivan Foeldvari⁷, Andrew Zeft⁸, Kathleen G Lomax⁹, Jill Gregson¹⁰, Abma Tineke¹¹, Sarah Campbell¹², Jeffrey Weiss¹², Dony Patel¹² and Nico Wulffraat¹³, ¹Pediatric Rheumatology, Children's Hospital Seattle, Seattle, WA, ²Department of Pediatrics, Asklepios Clinics St. Augustin, Sankt Augustin, Germany, ³Stanford University, Palo Alto, CA, ⁴University Hospitals Bristol, Bristol, United Kingdom, ⁵Hackensack University Medical Center, Hackensack, NJ, ⁶Necker-Enfants Malades Hospital, Paris, France, ⁷Kinder- und Jugenrheumatologie, Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, ⁸Pediatrics Rheumatology, Cleveland Clinic, Cleveland, OH, ⁹Novartis Pharmaceuticals Corporation, East Hanover, NJ, ¹⁰Novartis Pharma AG, Basel, Switzerland, ¹¹VU University medical center, Amsterdam, Netherlands, ¹²Navigant Consulting, Inc., London, United Kingdom, ¹³Wilhelmina Kinderziekenhuis, Utrecht, Netherlands
Background/Purpose: Systemic juvenile idiopathic arthritis (SJIA) is a severe autoinflammatory disease characterized by systemic features including high fevers, rash and arthritis. SJIA can impose high…
Abstract Number: 108 • 2017 Pediatric Rheumatology Symposium
Characteristics and long-term outcome of children and adolescents with initial diagnosis of Behçet’s disease in a tertiary care center in Brazil
Milagro Raquel Tovar-Avila¹, Francisco Hugo Gomes², Lucenir Da Silva³, Virginia Ferriani⁴ and Luciana Carvalho², ¹Pediatric Reumatology Division, Ribeirão Preto Medical School - University of São Paulo, Rbeirão Preto, Brazil, ²Pediatric Rheumatology Division, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil, ³Rheumatology Division, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil, ⁴Pediatric Reumatology Division, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil
Background/Purpose: Behet's disease (BD) is a rare systemic inflammatory disease with nonspecific clinical presentation that can mimic infections, tumors and other diseases. Diagnostic delay of…
Abstract Number: 9 • 2017 Pediatric Rheumatology Symposium
Biologically-Based Approach for Classifying Chronic Childhood Arthritis
Elham Rezaei¹, Daniel Hogan², Brett Trost², Anthony Kusalik², Susanne Benseler³, Gilles Boire⁴, David A. Cabral⁵, Bonnie Cameron⁶, Sarah Campillo⁷, Gaëlle Chédeville⁸, Paul Dancey⁹, Ciarán M. Duffy¹⁰, Karen N Watanabe Duffy¹¹, Janet Ellsworth¹², Simon Eng¹³, Brian M. Feldman¹⁴, John Gordon², Jaime Guzman¹⁵, Kristin Houghton¹⁶, Adam Huber¹⁷, Quaid Morris¹³, Bianca Lang¹⁸, Deborah M. Levy¹⁹, Loren Matheson²⁰, Kiem Oen²¹, Ross Petty²², Suzanne Ramsey²³, Johannes Roth²⁴, Dax Rumsey²⁵, Claire Saint-Cyr²⁶, Rayfel Schneider²⁷, Rosie Scuccimarri²⁸, Earl Silverman¹⁹, Lynn R. Spiegel²⁹, Elizabeth Stringer¹⁸, Shirley M.L. Tse³⁰, Lori Tucker³¹, Rae S.M. Yeung³² and Alan Rosenberg¹, ¹Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ²University of Saskatchewan, Saskatoon, SK, Canada, ³Pediatric Rheumatology, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada, ⁴Rheumatology Division, CHUS - Sherbrooke University, Sherbrooke, QC, Canada, ⁵Pediatrics/Rm K4-121, BC Children's Hospital, Vancouver, BC, Canada, ⁶The Hospital for Sick Children, Toronto, ON, Canada, ⁷Montreal Children's Hospital, Montreal, QC, Canada, ⁸Rheumatology, McGill University, Montreal, QC, Canada, ⁹Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, ¹⁰Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹¹Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹²University of Alberta, Edmonton, AB, Canada, ¹³University of Toronto, Toronto, ON, Canada, ¹⁴Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁵Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, ¹⁶Rheumatology/Pediatrics, British Columbia Childrens Hos, Vancouver, BC, Canada, ¹⁷IWK Health Centre, Halifax, NS, Canada, ¹⁸Dalhousie University, Halifax, NS, Canada, ¹⁹Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ²⁰University of Saskatchewan, Ottawa, ON, Canada, ²¹University of Manitoba, Winnipeg, MB, Canada, ²²Pediatric Rheumatology, Division of Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, ²³Pediatric Rheumatology, IWK Health Centre, Halifax, NS, Canada, ²⁴Pediatric Rheumatology, Children's Hospital Eastern On, Ottawa, ON, Canada, ²⁵Stollery Children's Hospital, Edmonton, AB, Canada, ²⁶Pediatrics, CHU Sainte-Justine, Montreal, QC, Canada, ²⁷Division of Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ²⁸Division of Pediatric Rheumatology, Montreal Children's Hospital/McGill University Health Centre, Montreal, QC, Canada, ²⁹Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ³⁰Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ³¹Pediatric Rheum/Rm K4-120, BC Childrens Hospital, Vancouver, BC, Canada, ³²Paediatrics, Immunology and Medical Science, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) comprises a heterogeneous group of conditions that share chronic arthritis as a common characteristic. International uniformity in classifying JIA, based…
Abstract Number: 66 • 2017 Pediatric Rheumatology Symposium
Feasibility Testing of An Internet-Based Psycho-Educational Game for Children with Juvenile Idiopathic Arthritis and Their Parents
Jennifer N. Stinson¹, Mark Connelly², Adam Huber³, Nadia Luca⁴, Lynn R. Spiegel⁵, Argerie Tsimicalis⁶, Stephanie Luca⁷, Naweed Tajuddin⁷, Roberta Berard⁸, Julie Barsalou⁹, Sarah Campillo^10,11, Brian Feldman¹², Shirley M.L. Tse¹³, Paul Dancey¹⁴, Ciarán M. Duffy¹⁵, Nicole Johnson¹⁶, Patrick McGrath³, Natalie J. Shiff¹⁷, Lori Tucker¹⁸ and J. Charles Victor¹⁹, ¹Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ²Children's Mercy Hospital, Kansas City, MO, ³IWK Health Centre, Halifax, NS, Canada, ⁴Pediatric Rheumatology, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada, ⁵Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ⁶McGill University, Montreal, QC, Canada, ⁷The Hospital for Sick Children, Toronto, ON, Canada, ⁸Pediatrics, Children's Hospital, London Health Sciences Centre, London, ON, Canada, ⁹CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada, ¹⁰Rheumatology, Montreal Children's Hospital, Montreal, QC, Canada, ¹¹Montreal Children's Hospital, Montreal, QC, Canada, ¹²Department of Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ¹³Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ¹⁴Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, ¹⁵Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹⁶Pediatrics, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada, ¹⁷University of Florida, Gainesville, FL, ¹⁸Pediatric Rheum/Rm K4-120, BC Childrens Hospital, Vancouver, BC, Canada, ¹⁹University of Toronto, Toronto, ON, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a common chronic illness in childhood. The responsibility of JIA management during the younger years is shared among family…
Abstract Number: 90 • 2017 Pediatric Rheumatology Symposium
Risk of Serious Infections in Juvenile Dermatomyositis patients treated with biological response modifiers including rituximab and abatacept
Sukesh Sukumaran¹ and Vini Vijayan², ¹ACH, UAMS, Little Rock, AR, ²Pediatrics, UAMS, Little Rock, AR
Background/Purpose: Juvenile dermatomyositis (JDM) is a rare systemic auto immune disease in children. The risk of infection is increased with immunomodulation. There are no studies…

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