Abstracts tagged "physical function"

Abstract Number: 1969 • ACR Convergence 2023
Multimorbidity and PROMIS Health Outcomes in Patients with Idiopathic Inflammatory Myopathies: Analysis from the COVAD Study
Marco Fornaro¹, Vincenzo Venerito², Florenzo Iannone³, Naveen R⁴, Elena Nikiphorou⁵, Mrudula Joshi⁶, Ai Lyn Tan⁷, Sreoshy Saha⁸, Samuel Shinjo⁹, Vishwesh Agarwal¹⁰, Nelly Ziade¹¹, Tsvetelina Velikova¹², Esha Kadam¹³, Marcin Milchert¹⁴, Ioannis Parodis¹⁵, Abraham Edgar Gracia-Ramos¹⁶, Lorenzo Cavagna¹⁷, Masataka Kuwana¹⁸, Johannes Knitza¹⁹, Ashima Makol²⁰, Dey Dzifa²¹, CARLOS ENRIQUE TORO GUTIERREZ²², CARLO VINICIO CABALLERO²³, Oliver Distler²⁴, Jessica Day²⁵, Hector Chinoy²⁶, Vikas Agarwal⁴, Rohit Aggarwal²⁷, Latika Gupta²⁸ and COVAD Study Group²⁹, ¹University of Bari, Grottaglie, Italy, ²Rheumatology Department, Università degli Studi di Bari, Bari, Italy, ³Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", Bari, Italy, ⁴Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, ⁵King's College London, London, United Kingdom, ⁶Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, ⁷University of Leeds, Leeds, United Kingdom, ⁸Mymensingh Medical College, Faridpur, Bangladesh, ⁹Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, ¹⁰Mahatma Gandhi Missions Medical College, Lucknow, India, ¹¹Saint-Joseph University, Beirut, Lebanon, ¹²Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria, ¹³Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, ¹⁴Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, ¹⁵Karolinska Institutet, Stockholm, Sweden, ¹⁶Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico, ¹⁷Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, ¹⁸Nippon Medical School Graduate School of Medicine, Tokyo, Japan, ¹⁹Department of Internal Medicine 3 Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, ²⁰Mayo Clinic, Rochester, MN, Rochester, MN, ²¹Department of Medicine and Therapeutics, University of Ghana School of Medicine and Dentistry, College of Health Sciences, Korle-Bu, Accra, Ghana, ²²Centro de Estudios de Reumatología y Dermatología SAS, Cali, Colombia, ²³REUMACARIBE IPS, Barranquilla, Colombia, ²⁴Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, ²⁵Walter and Eliza Hall Institute, Melbourne, Australia, ²⁶The University of Manchester, Sale, United Kingdom, ²⁷University of Pittsburgh, Pittsburgh, PA, ²⁸Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, ²⁹-, -
Background/Purpose: Comorbidities have a profound impact on the quality of life (QoL), though global data on the burden of comorbidities and its impact on health…
Abstract Number: 0553 • ACR Convergence 2022
Stair Climbing Difficulty and Risk of Functional Limitation in Knee Osteoarthritis: A Simple Functional Vital Sign?
Jason Jakiela¹, Dana Voinier¹, Yvonne Golightly², Jennifer Horney¹, Thomas Bye¹, Jéssica Bianca Aily¹ and Daniel White¹, ¹University of Delaware, Newark, DE, ²University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation in older adults, and difficulty with climbing stairs is often the first-reported limitation. As…
Abstract Number: 0739 • ACR Convergence 2022
Effect of Tailored Self-Management Interventions on Health Outcomes in Individuals with Chronic Musculoskeletal Conditions
Ellen Wang¹, Isabel Rodrigues² and Linda Li³, ¹University of British Columbia, Arthritis Research Canada, Vancouver, BC, Canada, ²McMaster University, GERAS Centre for Aging Research, Hamilton, ON, Canada, ³University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Self-management, has been recognized as an essential component of successful chronic musculoskeletal (MSK) management; yet existing reviews of self-management interventions have found only modest…
Abstract Number: 0851 • ACR Convergence 2022
Responsiveness of Patient-Reported Physical Function Measures in Juvenile Arthritis
Alysha Taxter¹, Laura Schanberg², Marc Natter³ and for the CARRA Registry investigators⁴, ¹Nationwide Children's Hospital, Columbus, OH, ²Duke University Medical Center, Durham, NC, ³Boston Children's Hospital, Boston, MA, ⁴CARRA, Washington, DC
Background/Purpose: The ACR Pediatric Criteria (ACR Pedi) contains a core set of outcome variables, including a measure of functional ability, to evaluate improvement over time…
Abstract Number: 0899 • ACR Convergence 2022
Performance of the Foot Function Index Questionnaire in Patients with Rheumatoid Arthritis
Joan Manuel Dapeña, Lucia Alascio, Eliana Rebeca Serrano, Juan Manuel Bande, Maria Alejandra Medina, Diana Silvia Klajn, Jose Angel Caracciolo and Silvia Beatriz Papasidero, Hospital General de Agudos Dr. Enrique Tornu, Buenos Aires, Argentina
Background/Purpose: Multiple questionnaires and objective assessment tools have been developed to determine functional compromise in Rheumatoid Arthritis (RA). One of the most used tools to…
Abstract Number: 1198 • ACR Convergence 2022
Validation of Remote Physical Performance and Cognitive Functioning Measures Among Individuals with Systemic Lupus Erythematosus
Courtney Hoge¹, C. Barrett Bowling², Charmayne Dunlop-Thomas¹, Bradley Pearce¹, S. Sam Lim¹, Cristina Drenkard¹ and Laura Plantinga¹, ¹Emory University, Atlanta, GA, ²Duke University, Durham, NC
Background/Purpose: The disruption of the COVID-19 pandemic presented an opportunity for researchers to develop and administer remote versions of measures for ongoing studies. In an…
Abstract Number: 1307 • ACR Convergence 2022
Effect of Romosozumab in Postmenopausal Women with Knee Osteoarthritis: Results from the FRAME Clinical Trial
Nancy Lane¹, Donald Betah², Cynthia Deignan², Mary Oates², Zhenxun Wang², Jen Timoshenko³, Aliya Khan⁴ and Neil Binkley⁵, ¹University of California Davis, Hillsborough, CA, ²Amgen, Inc., Thousand Oaks, CA, ³UCB Pharma, Slough, United Kingdom, ⁴McMaster University, Oakville, ON, Canada, ⁵University of Wisconsin, Madison, WI
Background/Purpose: Osteoarthritis (OA) and osteoporosis (OP) often occur concomitantly in the elderly. The relationship between OA and OP is complex, with increased fracture risk reported…
Abstract Number: 1491 • ACR Convergence 2022
Clinically Relevant Differences in the Mobility of Patients with Axial Spondyloarthritis Related to Daytime of Performance
David Kiefer¹, Juergen Braun¹, Lucia Schneider¹, Niklas Kolle¹, Uta Kiltz¹, Ioana Andreica², Philipp Sewerin¹, Bjoern Buehring³, susanne herbold¹ and Xenofon Baraliakos⁴, ¹Rheumazentrum Ruhrgebiet, Herne, Germany, ²Rheumazentrum Ruhrgebiet, Ruhr-Universität-Bochum, Herne, Germany, ³Bergisches Rheuma-Zentrum, Velbert, Germany, ⁴Rheumazentrum Ruhrgebiet Herne, Herne, Germany
Background/Purpose: Patients with axial spondyloarthritis (axSpA) often experience impairments of spinal mobility and physical function due to inflammation and structural damage. Back pain and morning…
Abstract Number: 1507 • ACR Convergence 2022
Diagnostic Delay of More Than 6 Months Contributes to Poor Patient-Reported Outcome Measures in Psoriatic Arthritis
Neel Tapryal¹, George Gondo², M. Elaine Husni³, Alice Gottlieb⁴ and Joseph Merola⁵, ¹Cleveland Clinic, Rocky River, OH, ²National Psoriasis Foundation, Portland, OR, ³Cleveland Clinic, Cleveland, OH, ⁴Department of Dermatology, The Icahn School of Medicine at Mount Sinai, New York, NY, ⁵Harvard Medical School, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Psoriatic arthritis (PsA) is a type of inflammatory arthritis in which the time between symptom onset and a diagnosis of PsA is highly variable.…
Abstract Number: 1847 • ACR Convergence 2022
Differences in Key Patient-reported Outcome Domains Identified by the Patient Acceptable Symptom State in the Adult SAPHO and Chronic Nonbacterial Osteomyelitis Observational Study (The SAPHO-CNO Study)
Aleksander Lenert¹, Robyn Domsic², Karmela Kim Chan³, Melissa Oliver⁴, Jisna Paul⁵, Courtney Kremer⁶, Emma Leisinger¹, Svjetlana Dolovcak⁷, Sandy D. Hong⁸, Aruni Jayatilleke⁹, Petar Lenert⁷, T. Shawn Sato¹, Samir Shah¹⁰, Shima Yasin¹¹, Yongdong (Dan) Zhao¹², Daniel Solomon¹³, Jonathan Templin¹ and Polly Ferguson¹¹, ¹University of Iowa, Iowa City, IA, ²University of Pittsburgh, Pittsburgh, PA, ³Hospital for Special Surgery, New York, NY, ⁴Indiana University School of Medicine, Indianapolis, IN, ⁵Ohio State University Hospital, Dublin, OH, ⁶University of Iowa Stead Family Children's Hospital, Solna, IA, ⁷University of Iowa Hospitals and Clinics, Iowa City, IA, ⁸University of Iowa Stead Family Children's Hospital, Iowa City, IA, ⁹Temple University, PHILADELPHIA, PA, ¹⁰Tufts Medical Center, Boston, MA, ¹¹University of Iowa Carver College of Medicine, Iowa City, IA, ¹²University of Washington, Redmond, WA, ¹³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Incorporating patient perspectives of their disease state is needed for disease activity assessment in adults with SAPHO syndrome and chronic nonbacterial osteomyelitis (CNO). The…
Abstract Number: 1897 • ACR Convergence 2022
A Preliminary Estimate of Objectively Measured Sedentary Behavior in Knee Osteoarthritis
Thomas Bye, Dana Voinier, Jason Jakiela, Jéssica Bianca Aily and Daniel White, University of Delaware, Newark, DE
Background/Purpose: Adults with knee osteoarthritis (OA) are thought to have elevated levels of sedentary behavior (SB). The Sedentary Behavior Research Network defines SB as total…
Abstract Number: 1973 • ACR Convergence 2022
Association Between Activity Limitations, Sleep Disturbance, Pain Sensitivity, Pain Intensity, and Widespread Pain in Adults with Rheumatoid Arthritis
Burcu Aydemir¹, Jing Song², Lutfiyya Muhammad³, Daniela Grimaldi¹, Kathryn Reid¹, Phyllis Zee¹, Rowland Chang⁴ and Yvonne Lee¹, ¹Northwestern University, Chicago, IL, ²Northwestern University, Evanston, IL, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Northwestern University Division of Rheumatology, Chicago, IL
Background/Purpose: Despite treatment with strong immunosuppressive medications, more than half of patients with rheumatoid arthritis (RA) still report pain. Pain can spread from joint sites…
Abstract Number: 0127 • ACR Convergence 2022
The Adult SAPHO and Chronic Nonbacterial Osteomyelitis Observational Study (The SAPHO-CNO Study) Supports Multidimensional Disease Symptomatology with High Levels of Pain and Fatigue, and Low Levels of Function
Aleksander Lenert¹, Robyn Domsic², Karmela Kim Chan³, Melissa Oliver⁴, Jisna Paul⁵, Courtney Kremer⁶, Emma Leisinger¹, Svjetlana Dolovcak⁷, Sandy D. Hong⁸, Aruni Jayatilleke⁹, Petar Lenert⁷, T. Shawn Sato¹, Samir Shah¹⁰, Shima Yasin¹¹, Yongdong (Dan) Zhao¹², Daniel Solomon¹³, Jonathan Templin¹ and Polly Ferguson¹¹, ¹University of Iowa, Iowa City, IA, ²University of Pittsburgh, Pittsburgh, PA, ³Hospital for Special Surgery, New York, NY, ⁴Indiana University School of Medicine, Indianapolis, IN, ⁵Ohio State University Hospital, Dublin, OH, ⁶University of Iowa Stead Family Children's Hospital, Solna, IA, ⁷University of Iowa Hospitals and Clinics, Iowa City, IA, ⁸University of Iowa Stead Family Children's Hospital, Iowa City, IA, ⁹Temple University, PHILADELPHIA, PA, ¹⁰Tufts Medical Center, Boston, MA, ¹¹University of Iowa Carver College of Medicine, Iowa City, IA, ¹²University of Washington, Redmond, WA, ¹³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Quality of life (QOL) and disease impact are important to adults with SAPHO syndrome and chronic nonbacterial osteomyelitis (CNO) but remain poorly described. Patient-reported…
Abstract Number: 2009 • ACR Convergence 2022
Long-term Outcome of a Treat-to-target Strategy in Elderly-onset Rheumatoid Arthritis with Chronic Lung Diseases
Manami Nomura¹, Takahiko Sugihara², Hiroyuki Baba¹, Tatsuro Ishizaki³, Tadashi Hosoya¹, Mari Kamiya¹, Takumi Matsumoto², Kanae Kubo⁴, Fumio Hirano⁵, Masayo Kojima⁶, Nobuyuki Miyasaka⁵, Shinsuke Yasuda⁵ and Masayoshi Harigai⁷, ¹Tokyo Medical and Dental University (TMDU), Tokyo, Japan, ²Department of Medicine and Rheumatology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan, ³Human Care Research Team, Tokyo Metropolitan Institute of Gerontology., Tokyo, Japan, ⁴Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan, ⁵Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, ⁶Department of Frailty Research, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Nagoya, Japan, ⁷Division of Rheumatology, Department of Internal Medicine, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan
Background/Purpose: Elderly patients with rheumatoid arthritis (RA) tend to have a higher risk for drug-related adverse events (AEs) than younger patients, and the effectiveness and…
Abstract Number: 0207 • ACR Convergence 2022
Novel Digital Technologies for the Assessment of Objective Measures and PROs in Patients with Rheumatoid Arthritis: A Pilot Study Using Smart Devices and a Bespoke Mobile App
Valentin Hamy¹, Christopher Llop², Christopher W Yee², Luis Garcia-Gancedo³, Aoife Maxwell⁴, Wen-Hung Chen⁵, Ryan Tomlinson³, Priyanka Bobbili², Julien Bendelac², Jessica Landry², Maral DerSarkissian⁶, Mihran Yenikomshian², Elinor A Mody⁷, Mei Sheng Duh² and Rachel Williams³, ¹GlaxoSmithKline, London, United Kingdom, ²Analysis Group Inc, Boston, MA, ³GlaxoSmithKline, Philadephia, ⁴GlaxoSmithKline, Stevenage, United Kingdom, ⁵GlaxoSmithKline, Value Evidence and Outcomes, Philadephia, ⁶Analysis Group Inc, Los Angeles, CA, ⁷Reliant Medical Group, Worcester, MA
Background/Purpose: RA symptoms are typically only assessed intermittently in clinical practice and clinical trials. Digital technologies (wearables, smartphones) can facilitate continuous remote monitoring of patients'…

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