ACR Meeting Abstracts

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Abstracts tagged "physical function"

  • Abstract Number: 0990 • ACR Convergence 2023

    Association of Treatment and Disease Activity with Antibiotic Use and Hospitalized Infection Among People Living with Rheumatoid Arthritis: Baseline Data from a Longitudinal Study in the ArthritisPower Registry

    Kelly Gavigan1, Esteban Rivera2, Odette Kolenky3, Cassie Clinton4, Emily Holladay4, David Curtis5, Laura Stradford6, Jeffrey Curtis4, W. Benjamin Nowell6, Christian Curtis7 and Michael George8, 1Global Healthy Living Foundation, Upper Nyack, NY, 2Global Healthy Living Foundation, Long Island City, NY, 3Hospital of the University of Pennsylvania, Philadelphia, PA, 4University of Alabama at Birmingham, Birmingham, AL, 5Global Healthy Living Foundation, San Francisco, CA, 6Global Healthy Living Foundation, Nyack, NY, 7Illumination Health, Birmingham, AL, 8University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Infections are a major contributor to morbidity and mortality in patients (pts) with rheumatoid arthritis (RA). Little is known about the risk of non-serious…
  • Abstract Number: 1847 • ACR Convergence 2022

    Differences in Key Patient-reported Outcome Domains Identified by the Patient Acceptable Symptom State in the Adult SAPHO and Chronic Nonbacterial Osteomyelitis Observational Study (The SAPHO-CNO Study)

    Aleksander Lenert1, Robyn Domsic2, Karmela Kim Chan3, Melissa Oliver4, Jisna Paul5, Courtney Kremer6, Emma Leisinger1, Svjetlana Dolovcak7, Sandy D. Hong8, Aruni Jayatilleke9, Petar Lenert7, T. Shawn Sato1, Samir Shah10, Shima Yasin11, Yongdong (Dan) Zhao12, Daniel Solomon13, Jonathan Templin1 and Polly Ferguson11, 1University of Iowa, Iowa City, IA, 2University of Pittsburgh, Pittsburgh, PA, 3Hospital for Special Surgery, New York, NY, 4Indiana University School of Medicine, Indianapolis, IN, 5Ohio State University Hospital, Dublin, OH, 6University of Iowa Stead Family Children's Hospital, Solna, IA, 7University of Iowa Hospitals and Clinics, Iowa City, IA, 8University of Iowa Stead Family Children's Hospital, Iowa City, IA, 9Temple University, PHILADELPHIA, PA, 10Tufts Medical Center, Boston, MA, 11University of Iowa Carver College of Medicine, Iowa City, IA, 12University of Washington, Redmond, WA, 13Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Incorporating patient perspectives of their disease state is needed for disease activity assessment in adults with SAPHO syndrome and chronic nonbacterial osteomyelitis (CNO). The…
  • Abstract Number: 1897 • ACR Convergence 2022

    A Preliminary Estimate of Objectively Measured Sedentary Behavior in Knee Osteoarthritis

    Thomas Bye, Dana Voinier, Jason Jakiela, Jéssica Bianca Aily and Daniel White, University of Delaware, Newark, DE

    Background/Purpose: Adults with knee osteoarthritis (OA) are thought to have elevated levels of sedentary behavior (SB). The Sedentary Behavior Research Network defines SB as total…
  • Abstract Number: 1973 • ACR Convergence 2022

    Association Between Activity Limitations, Sleep Disturbance, Pain Sensitivity, Pain Intensity, and Widespread Pain in Adults with Rheumatoid Arthritis

    Burcu Aydemir1, Jing Song2, Lutfiyya Muhammad3, Daniela Grimaldi1, Kathryn Reid1, Phyllis Zee1, Rowland Chang4 and Yvonne Lee1, 1Northwestern University, Chicago, IL, 2Northwestern University, Evanston, IL, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Northwestern University Division of Rheumatology, Chicago, IL

    Background/Purpose: Despite treatment with strong immunosuppressive medications, more than half of patients with rheumatoid arthritis (RA) still report pain. Pain can spread from joint sites…
  • Abstract Number: 0127 • ACR Convergence 2022

    The Adult SAPHO and Chronic Nonbacterial Osteomyelitis Observational Study (The SAPHO-CNO Study) Supports Multidimensional Disease Symptomatology with High Levels of Pain and Fatigue, and Low Levels of Function

    Aleksander Lenert1, Robyn Domsic2, Karmela Kim Chan3, Melissa Oliver4, Jisna Paul5, Courtney Kremer6, Emma Leisinger1, Svjetlana Dolovcak7, Sandy D. Hong8, Aruni Jayatilleke9, Petar Lenert7, T. Shawn Sato1, Samir Shah10, Shima Yasin11, Yongdong (Dan) Zhao12, Daniel Solomon13, Jonathan Templin1 and Polly Ferguson11, 1University of Iowa, Iowa City, IA, 2University of Pittsburgh, Pittsburgh, PA, 3Hospital for Special Surgery, New York, NY, 4Indiana University School of Medicine, Indianapolis, IN, 5Ohio State University Hospital, Dublin, OH, 6University of Iowa Stead Family Children's Hospital, Solna, IA, 7University of Iowa Hospitals and Clinics, Iowa City, IA, 8University of Iowa Stead Family Children's Hospital, Iowa City, IA, 9Temple University, PHILADELPHIA, PA, 10Tufts Medical Center, Boston, MA, 11University of Iowa Carver College of Medicine, Iowa City, IA, 12University of Washington, Redmond, WA, 13Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Quality of life (QOL) and disease impact are important to adults with SAPHO syndrome and chronic nonbacterial osteomyelitis (CNO) but remain poorly described. Patient-reported…
  • Abstract Number: 2009 • ACR Convergence 2022

    Long-term Outcome of a Treat-to-target Strategy in Elderly-onset Rheumatoid Arthritis with Chronic Lung Diseases

    Manami Nomura1, Takahiko Sugihara2, Hiroyuki Baba1, Tatsuro Ishizaki3, Tadashi Hosoya1, Mari Kamiya1, Takumi Matsumoto2, Kanae Kubo4, Fumio Hirano5, Masayo Kojima6, Nobuyuki Miyasaka5, Shinsuke Yasuda5 and Masayoshi Harigai7, 1Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 2Department of Medicine and Rheumatology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan, 3Human Care Research Team, Tokyo Metropolitan Institute of Gerontology., Tokyo, Japan, 4Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan, 5Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, 6Department of Frailty Research, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Nagoya, Japan, 7Division of Rheumatology, Department of Internal Medicine, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan

    Background/Purpose: Elderly patients with rheumatoid arthritis (RA) tend to have a higher risk for drug-related adverse events (AEs) than younger patients, and the effectiveness and…
  • Abstract Number: 0207 • ACR Convergence 2022

    Novel Digital Technologies for the Assessment of Objective Measures and PROs in Patients with Rheumatoid Arthritis: A Pilot Study Using Smart Devices and a Bespoke Mobile App

    Valentin Hamy1, Christopher Llop2, Christopher W Yee2, Luis Garcia-Gancedo3, Aoife Maxwell4, Wen-Hung Chen5, Ryan Tomlinson3, Priyanka Bobbili2, Julien Bendelac2, Jessica Landry2, Maral DerSarkissian6, Mihran Yenikomshian2, Elinor A Mody7, Mei Sheng Duh2 and Rachel Williams3, 1GlaxoSmithKline, London, United Kingdom, 2Analysis Group Inc, Boston, MA, 3GlaxoSmithKline, Philadephia, 4GlaxoSmithKline, Stevenage, United Kingdom, 5GlaxoSmithKline, Value Evidence and Outcomes, Philadephia, 6Analysis Group Inc, Los Angeles, CA, 7Reliant Medical Group, Worcester, MA

    Background/Purpose: RA symptoms are typically only assessed intermittently in clinical practice and clinical trials. Digital technologies (wearables, smartphones) can facilitate continuous remote monitoring of patients'…
  • Abstract Number: 2118 • ACR Convergence 2022

    Achieving Increasingly Stringent Clinical Disease Control Criteria Is Associated with Greater Improvements in Patient-Centric Measures of Physical Function and Pain in Patients with Active PsA: 16-Week Results from Two Phase 3 Randomized, Placebo-Controlled Studies

    Jessica Walsh1, Laura Coates2, Philip J Mease3, Joseph Merola4, Peter Nash5, Alexis Ogdie6, William Tillett7, Paolo Gisondi8, Barbara Ink9, Deepak Assudani9, Rajan Bajracharya9, Jérémy Lambert10, Vanessa Taieb11, Damon Willems12 and Lars Erik13, 1University of Utah, Salt Lake City, UT, 2Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, England, United Kingdom, 3Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, 4Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 5School of Medicine, Griffith University, Sunshine Coast, Australia, 6Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 7Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 8Dermatology and Venereology, Department of Medicine, Università di Verona, Verona, Italy, Verona, 9UCB Pharma, Slough, United Kingdom, 10UCB Pharma, Colombes, France, Irigny, France, 11UCB Pharma, Colombes, France, 12UCB Pharma, Brussels, Belgium, 13Bispebjerg-Frederiksberg Hospital, Vedbæk, Denmark

    Background/Purpose: Examine the association between achieving increasingly stringent clinical disease control criteria and patient-centric measures of physical function and pain in patients with PsA, using…
  • Abstract Number: 0410 • ACR Convergence 2022

    Achieving Increasingly Stringent Clinical Response Criteria & Lower Levels of Disease Activity Is Associated with Greater Improvements in Physical Function & HRQoL in Patients with Active Axial Spondyloarthritis: 16-Week Results from Two Phase 3 Randomized, Placebo-Controlled Studies

    Marina Magrey1, Atul Deodhar2, Philip J Mease3, Victoria Navarro-Compán4, Sofia Ramiro5, Martin Rudwaleit6, Christine de la Loge7, Carmen Fleurinck8, Vanessa Taieb9, Michael Frank Mørup10, Marga Oortgiesen11 and Jonathan Kay12, 1Case Western Reserve University, University Hospitals, Richfield, OH, 2Oregon Health & Science University, Portland, OR, USA, Portland, OR, 3Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, 4Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 5Leiden University Medical Center, Leiden, Netherlands, 6University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, 7UCB Pharma, Brussels, Belgium, 8UCB Pharma, Brussels, Belgium, Oosterzele, Belgium, 9UCB Pharma, Colombes, France, 10UCB Pharma, Copenhagen, Denmark, 11UCB Pharma, Raleigh, NC, 12Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA

    Background/Purpose: Examine the association between achieving increasingly stringent clinical response criteria and lower levels of disease activity, and improvements in physical function and health-related quality…
  • Abstract Number: 2239 • ACR Convergence 2022

    Effect of Treatment with IVIG (octagam10%) on Skin Symptoms and Quality of Life in Subjects with Dermatomyositis. Results of a Large, Randomized, Placebo-controlled International Phase III Trial

    Rohit Aggarwal1, Christina Charles-Schoeman2, joachim Schessl3, Victoria Werth4, Zsuzsanna Bata-Csorgo5, Mazen Dimachkie6, Zoltan Griger7, Sergey Moiseev8, Chester Oddis9, Elena Schiopu10, Jiří Vencovský11, Irene Beckmann12, Elisabeth Clodi13, Todd Levine14 and and the ProDERM investigators15, 1Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 2Division of Rheumatology, University of California, Los Angeles, Santa Monica, CA, 3Friedrich-Baur-Institut/Medical University Munich, Mainkofen, Germany, 4Philadelphia VAMC, Philadelphia, PA, USA and Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, 5University of Szeged, Faculty of Medicine, Szeged, Hungary, 6University of Kansas Medical Center, Kansas City, KS, 7University of Debrecen, Debrecen, Hungary, 8First Moscow State Medical University, Moscow, Russia, 9University of Pittsburgh, Pittsburgh, PA, 10Michigan Medicine Rheumatology Clinic – Taubman Center, Ann Arbor, MI, 11Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 12Octapharma PharmazeutikaProduktionsGesmbH, Vienna, Austria, 13Octapharma Pharmazeutika ProduktionsgesmbH, Vienna, Austria, 14Phoenix Neurological Associates, Ltd., Phoenix, AZ, 15Institutions in Europe and North America, Vienna, Austria

    Background/Purpose: Dermatomyositis (DM) is a rare chronic systemic autoimmune disease with characteristic skin rashes and progressive proximal muscle weakness. The efficacy of IVIg treatment in…
  • Abstract Number: 0412 • ACR Convergence 2022

    Bimekizumab Improves Physical Function and Health-Related Quality of Life in Patients with Axial Spondyloarthritis: Results from Two Phase 3 Studies

    Maureen Dubreuil1, Karl Gaffney2, Lianne Gensler3, Jonathan Kay4, Victoria Navarro-Compán5, Christine de la Loge6, Alicia Ellis7, Carmen Fleurinck8, Marga Oortgiesen9, Vanessa Taieb10 and Atul Deodhar11, 1Department of Rheumatology, Boston University School of Medicine, Boston, MA, 2Norfolk and Norwich University Hospital NHS Trust, Norfolk, United Kingdom, 3Department of Medicine, Division of Rheumatology, University of California San Francisco, San Francisco, CA, 4Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA, 5Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 6UCB Pharma, Brussels, Belgium, 7UCB Pharma, Raleigh, 8UCB Pharma, Brussels, Belgium, Oosterzele, Belgium, 9UCB Pharma, Raleigh, NC, 10UCB Pharma, Colombes, France, 11Oregon Health & Science University, Portland, OR, USA, Portland, OR

    Background/Purpose: Axial spondyloarthritis (axSpA) severely impacts patients' (pts) physical function and health-related quality of life (HRQoL).1 Bimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively…
  • Abstract Number: 0503 • ACR Convergence 2022

    The Effect of Social Isolation on 1-Year Outcomes After Surgical Repair of Low Trauma Hip Fracture

    Robyn Lipschultz1, Dina Sheira1, Marianna Frey2, Mangala Rajan3, Joseph Lane1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of Rochester School of Medicine and Dentistry, New York, NY, 3Weill Cornell Medicine, New York, NY

    Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over 65 years old. Social isolation—how integrated a…
  • Abstract Number: 0553 • ACR Convergence 2022

    Stair Climbing Difficulty and Risk of Functional Limitation in Knee Osteoarthritis: A Simple Functional Vital Sign?

    Jason Jakiela1, Dana Voinier1, Yvonne Golightly2, Jennifer Horney1, Thomas Bye1, Jéssica Bianca Aily1 and Daniel White1, 1University of Delaware, Newark, DE, 2University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation in older adults, and difficulty with climbing stairs is often the first-reported limitation. As…
  • Abstract Number: 0739 • ACR Convergence 2022

    Effect of Tailored Self-Management Interventions on Health Outcomes in Individuals with Chronic Musculoskeletal Conditions

    Ellen Wang1, Isabel Rodrigues2 and Linda Li3, 1University of British Columbia, Arthritis Research Canada, Vancouver, BC, Canada, 2McMaster University, GERAS Centre for Aging Research, Hamilton, ON, Canada, 3University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: Self-management, has been recognized as an essential component of successful chronic musculoskeletal (MSK) management; yet existing reviews of self-management interventions have found only modest…
  • Abstract Number: 0851 • ACR Convergence 2022

    Responsiveness of Patient-Reported Physical Function Measures in Juvenile Arthritis

    Alysha Taxter1, Laura Schanberg2, Marc Natter3 and for the CARRA Registry investigators4, 1Nationwide Children's Hospital, Columbus, OH, 2Duke University Medical Center, Durham, NC, 3Boston Children's Hospital, Boston, MA, 4CARRA, Washington, DC

    Background/Purpose: The ACR Pediatric Criteria (ACR Pedi) contains a core set of outcome variables, including a measure of functional ability, to evaluate improvement over time…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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