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Abstracts tagged "physical function"

  • Abstract Number: 0536 • ACR Convergence 2020

    Systematic Geriatric Assessment in Older Patients with Rheumatic Diseases – The RheuMAGIC Pilot Study

    Bjoern Buehring1, Anna Berrisch2, Ioana Andreica3, Styliani Tsiami4, David Kiefer3, Uta Kiltz2, Xenofon Baraliakos2 and Juergen Braun2, 1Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Velbert, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Current demographic data predict that the number of older adults with rheumatic diseases will considerably increase in the coming years. Geriatric patients differ from…
  • Abstract Number: 0551 • ACR Convergence 2020

    Physical Performance as a Mediator of the Association Between Depression and Pain in Knee Osteoarthritis

    Alan Rathbun1, Elizabeth Stuart2, Michelle Shardell1, Trang Nguyen2, Alice Ryan1, Joseph Gallo2, Michelle Yau3, Megan Schuler4 and Marc Hochberg1, 1University of Maryland School of Medicine, Baltimore, MD, 2Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 3Hinda and Arthur Marcus Institute for Aging Research, Boston, MA, 4RAND Corporation, Boston, MA

    Background/Purpose: Depression is common in knee osteoarthritis (OA), and leads to reduced physical function, which may mediate the effect of depression on pain. However, research…
  • Abstract Number: 0744 • ACR Convergence 2020

    Circulating Fibroblast Growth Factor-21 Levels in Rheumatoid Arthritis: Associations with Disease Characteristics, Body Composition, and Physical Functioning

    Patrick Gould1, Babette Zemel2, Elena Taratuta3 and Joshua Baker1, 1University of Pennsylvania, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, 3University of Pennsylvania, Philadelphia

    Background/Purpose: Rheumatoid arthritis (RA) can lead to changes in body composition, including muscle loss and excess adiposity, which are in turn associated with physical disability.…
  • Abstract Number: 0931 • ACR Convergence 2020

    Oropharyngeal Dysfunction in Patients with Systemic Sclerosis – Results of a Monocentric Clinical Study

    Philipp Klemm1, Mirjam Wirths2, Ole Hudowenz2, Ulrike Hoffmann3, Ulf Müller-Ladner2 and Uwe Lange2, 1Department of Rheumatology, Immunology, Osteology and Physical Medicine, Justus Liebig University Gießen, Campus Kerckhoff, Bad Nauheim, Germany, Bad Nauheim, Hessen, Germany, 2Department of Rheumatology, Immunology, Osteology and Physical Medicine, Justus Liebig University Gießen, Campus Kerckhoff, Bad Nauheim, Germany, Bad Nauheim, Germany, 3Practice for Speech Therapy Ulrike Hoffmann, Friedberg, Germany

    Background/Purpose: Nearly 98% of patients with systemic sclerosis (SSc) are suffering from gastrointestinal involvement (Schmeiser et al. 2012). While in everyday clinical practice screening for…
  • Abstract Number: 1084 • ACR Convergence 2020

    Consumer-based Activity Trackers in Evaluation of Physical Function in Myositis Patients

    Didem Saygin1, Bonny Rockette-Wagner2, Chester Oddis3, Diane Koontz1, Siamak Moghadam-Kia1 and Rohit Aggarwal2, 1University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3Department of Medicine, Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Idiopathic inflammatory myopathies are systemic inflammatory conditions characterized by muscle weakness and reduced muscle endurance that limit activities of daily living. Daily step count…
  • Abstract Number: 1375 • 2019 ACR/ARP Annual Meeting

    Patient-Reported Outcomes of Upadacitinib versus Adalimumab Use in Patients with Moderately to Severely Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate: 26-Week Analysis of a Phase 3 Study

    Roy Fleischmann1, Martin Bergman 2, Namita Tundia 3, In-Ho Song 4, Jessica Suboticki 4, Yan Song 5 and Vibeke Strand 6, 1Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 2Drexel University College of Medicine, Stockholm, Sweden, 3AbbVie Inc., North Chicago, IL, 4AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, 5Analysis Group, Inc., Boston, MA, 6Division of Immunology/Rheumatology, Stanford University, Stanford, CA

    Background/Purpose: In patients with active rheumatoid arthritis (RA), 12-week treatment with upadacitinib (UPA) while on background MTX therapy resulted in significant and clinically meaningful improvements…
  • Abstract Number: 1376 • 2019 ACR/ARP Annual Meeting

    Impact of 24- or 26-Week Upadacitinib Monotherapy on Patient-Reported Outcomes in Patients with Moderately to Severely Active Rheumatoid Arthritis and No Prior Use of or an Inadequate Response to Methotrexate: Results from Two Phase 3 Trials

    Vibeke Strand1, Namita Tundia 2, Alan Friedman 3, Heidi Camp 2, Jessica Suboticki 4, Debbie Goldschmidt 5, Catherine Fernan 5 and Martin Bergman 6, 1Division of Immunology/Rheumatology, Stanford University, Stanford, CA, 2AbbVie Inc., North Chicago, IL, 3AbbVie Inc., North Chicago, 4AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, 5Analysis Group, Inc., New York, NY, 6Drexel University College of Medicine, Stockholm, Sweden

    Background/Purpose: Treatment with upadacitinib (UPA) monotherapy, a selective Janus kinase-1 (JAK-1) inhibitor, resulted in significant and clinically meaningful improvements in patient-reported outcomes (PROs) at Week…
  • Abstract Number: 2089 • 2019 ACR/ARP Annual Meeting

    Restricting Activity to Evade Knee Symptoms Is Associated with Worse Physical Function and Radiographic Osteoarthritis

    Louise Thoma1, Jason Jakiela 2, Hiral Master 1, Dana Voinier 2, Meredith Christiansen 2 and Daniel White 1, 1University of Delaware, Newark, DE, 2University of Delaware, Newark

    Background/Purpose: Activity restriction (i.e. limiting or avoiding normal activity) is a common strategy to reduce, and sometimes eliminate, knee symptoms. Knee symptoms, such as pain,…
  • Abstract Number: 2160 • 2019 ACR/ARP Annual Meeting

    Myopenia Is an Independent Risk Factor for Rotator Cuff Tear and Shoulder Dysfunction in Elderly People : Data from NAMGARAM Cohort

    Yun-Hong Cheon1, Young Sun Suh 2, Mingyo Kim 1, Ki-Soo Park 3 and Sang-Il Lee 1, 1Divison of Rheumatology, Gyeongsang National University Hospital, Jin-Ju, Republic of Korea, 2Divison of Rheumatology, Gyeongsang National University Hospital, Changwon, Changwon, Republic of Korea, 3Preventive Medicine, Gyeongsang National University Hospital, Jin-Ju, Republic of Korea

    Background/Purpose: Myopenia refers to decline in muscle mass with age, causing significant impairment in the ability to carry out normal daily functions. Rotator cuff tear…
  • Abstract Number: 2174 • 2019 ACR/ARP Annual Meeting

    Test-Retest Reliability and Validity of a Mobile Health Application to Automate the 30 Seconds Chair Stand Test – Preliminary Data to Create a Contemporary Instrument for Randomized Clinical Trials

    Lucas Dantas1, Matthew Harkey 2, André Dantas 3, Lori Lyn Price 4, Jeffrey Driban 5 and Timothy McAlindon 1, 1Tufts Medical Center, Boston, MA, 2Tufts Medical Center, University of Massachusetts Medical School, Boston, MA, 3CI&T, Tokyo, Japan, 4Tufts Medical Center, Tufts University, Boston, MA, 5Tufts Medical Center, Boston

    Background/Purpose: Contemporary technologies offer potential solutions to improve and automate data collection of randomized clinical trials by transitioning assessments from the clinic to the real-world.…
  • Abstract Number: 2186 • 2019 ACR/ARP Annual Meeting

    What Is an Important Difference in Gait Speed in Adults with Knee Osteoarthritis?

    Jing Song 1, David Cella 2, Abigail Gilbert3, Rowland Chang 2 and Dorothy Dunlop 2, 1Northwestern University Feinberg School of Medicine, Worthington, OH, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3University of North Carolina, Chapel Hill, NC

    Background/Purpose: Little is known regarding what difference in functional performance measures are clinically significant in individuals with a chronic medical disease. This study examines the…
  • Abstract Number: 2259 • 2019 ACR/ARP Annual Meeting

    Physical Challenges in RA: A Qualitative Study of an Online Patient Support Group

    Jude des Bordes 1, Jessica Foreman 1, Maria Lopez-Olivo1, Susan K Peterson 1, Tiffany Westrich-Robertson 2, Catherine Hofstetter 3, Anne Lyddiatt 4, Amye Leong 5 and Maria E. Suárez-Almazor 6, 1The University of Texas, MD Anderson Cancer Center, Houston, TX, 2International Foundation for Autoimmune and Autoinflammatory Arthritis, Saint Louis, MO, 3Patient advocate, Toronto, ON, Canada, 4Musculoskeletal Group, Cochrane Collaboration, Toronto, ON, Canada, 57. Healthy Motivation and the Global Alliance for Musculoskeletal Health of the Bone and Joint Decade, Santa Barbara, CA, 6Department of Rheumatology/Clinical Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX , USA., Houston, TX

    Background/Purpose: Patients with rheumatoid arthritis (RA) face a number of challenges which adversely affect their quality of life. The objective was to qualitatively evaluate content…
  • Abstract Number: 2453 • 2019 ACR/ARP Annual Meeting

    Static and Longitudinal Construct Validity of PROMIS CAT and Profile29 for Assessing Pain Interference, Physical Function and Fatigue in Psoriatic Arthritis

    Ana-Maria Orbai1, Jamie Perin 2, Albert W Wu 3, Katherine C. Smith 4 and Clifton Bingham 5, 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins University School of Public Health, Department of International Health, Baltimore, 3Johns Hopkins University Bloomberg School of Public Health, Department of Health Policy and Management, Baltimore, MD, 4Johns Hopkins University Bloomberg School of Public Health, Department of Health, Behavior and Society, Baltimore, MD, 5Johns Hopkins University, Baltimore, MD

    Background/Purpose: Pain, physical function and fatigue are outcomes reported as having the greatest importance to people with psoriatic arthritis (PsA)1,2. We assessed these outcomes in…
  • Abstract Number: 561 • 2019 ACR/ARP Annual Meeting

    Analysing Impairments in Physical Performance as Assessed by the as Performance Index (ASPI) in Patients with Axial Spondyloarthritis (axSpA)

    Eerik Ahomaa 1, Uta Kiltz2, Björn Bühring 3, Xenofon Baraliakos 4, Salima van weely 5 and Jürgen Braun 6, 1Rheumazentrum Ruhrgebiet and Ruhr-University Bochum, Bochum, Germany, 2Rheumazentrum Ruhrgebiet/Ruhr University Bochum, Herne, Germany, Herne, Germany, 3Rheumazentrum Ruhrgebiet and Ruhr-University Bochum, Herne, Germany, 4Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, 5Orthopedics, Rehabilitation and Physical Therapy dpt., Leiden University Medical Center, Leiden, Netherlands, 6Rheumazentrum Ruhrgebiet/Ruhr University, Herne, Germany

    Background/Purpose: In patients with axial spondyloarthritis (axSpA) physical functioning is frequently impaired. The current gold standard to assess physical functioning is self-reported questionnaires (i.e. BASFI),…
  • Abstract Number: 612 • 2019 ACR/ARP Annual Meeting

    Objective Ankylosing Spondylitis Physical Performance Index (ASPI) Is Highly Reliable and Feasible in Chilean Patients

    Rianne van Bentum1, Sebastian Ibáñez Vodnizza 2, Francisca Valenzuela Aldridge 2, Maria Paz Poblete 3, Salima van weely 4, Marieke ter Wee 1, Omar Valenzuela 5 and Irene van der Horst-Bruinsma 1, 1Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, 2Rheumatology dpt., Clínica Alemana - UDD Medicine faculty, Santiago, Chile, 3Rheumatology dpt., Facultad de Medicina Clinica Alemana - UDD, Santiago, Region Metropolitana, Chile, 4Orthopedics, Rehabilitation and Physical Therapy dpt., Leiden University Medical Center, Leiden, Netherlands, 5Facultad de Medicina Clinica Alemana -UDD, Santiago, Region Metropolitana, Chile

    Background/Purpose: In axial spondyloarthritis (axSpA), preservation of physical functioning is an important treatment goal and is usually assessed with the patient-reported BASFI questionnaire. The Ankylosing…
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