ACR Meeting Abstracts

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Abstracts tagged "physical function"

  • Abstract Number: 1970 • ACR Convergence 2023

    Impaired Health-Related Quality of Life in Patients with Idiopathic Inflammatory Myopathies: A Cross-Sectional Analysis from the COVAD Dataset

    Akira Yoshida1, Yuan Li2, Vahed Maroufy2, Masataka Kuwana1, Naveen R3, Ashima Makol4, Parikshit Sen5, James Lilleker6, Vishwesh Agarwal7, Sinan Kardes8, Jessica Day9, Marcin Milchert10, Mrudula Joshi11, Tamer A Gheita12, Babur Salim13, Tsvetelina Velikova14, Abraham Edgar Gracia-Ramos15, Ioannis Parodis16, Elena Nikiphorou17, Ai Lyn Tan18, Arvind Nune19, Lorenzo Cavagna20, Miguel Angel Saavedra Salinas21, Samuel Shinjo22, Nelly Ziade23, Johannes Knitza24, Oliver Distler25, Hector Chinoy26, Vikas Agarwal3, Rohit Aggarwal27, Latika Gupta28 and COVAD Study Group29, 1Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 2University of Texas Health Science Center at Houston, Houston, TX, 3Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 4Mayo Clinic, Rochester, MN, Rochester, MN, 5Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 6Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK. Orcid ID: 0000-0002-9230-4137., Manchester, United Kingdom, 7Mahatma Gandhi Missions Medical College, Lucknow, India, 8Istanbul University, Istanbul, Turkey, 9Walter and Eliza Hall Institute, Melbourne, Australia, 10Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, 11Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 12Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt, 13Fauji foundation hospital Rawalpindi, Rawalpindi, Pakistan, 14Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 15Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico, 16Karolinska Institutet, Stockholm, Sweden, 17King's College London, London, United Kingdom, 18University of Leeds, Leeds, United Kingdom, 19Southport & Ormskirk NHS Foundation Trust, Liverpool, United Kingdom, 20Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 21IMSS, Mexico City, Mexico, 22Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, 23Saint-Joseph University, Beirut, Lebanon, 24Department of Internal Medicine 3 Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, 25Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 26The University of Manchester, Sale, United Kingdom, 27University of Pittsburgh, Pittsburgh, PA, 28Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 29-, -

    Background/Purpose: The significance of Health-related quality of life (HRQoL) in patients with autoimmune diseases is well acknowledged. Unfortunately, there is dearth of data on the…
  • Abstract Number: 0285 • ACR Convergence 2023

    Patient Reported Physical Function, Mental Health, and Treatment Patterns in Dermatomyositis

    Lisa Christopher-Stine1, Julie Paik1, Brendan M. Johnson2, Taryn Smith2, Jolie Feldman2 and Paul N. Mudd Jr.2, 1Johns Hopkins University, Baltimore, MD, 2Priovant Therapeutics, Durham, NC

    Background/Purpose: Dermatomyositis (DM) is a rare, debilitating, idiopathic inflammatory myopathy characterized by painful, itchy skin rash and proximal muscle weakness that can significantly impact daily…
  • Abstract Number: 1985 • ACR Convergence 2023

    Preliminary Results for the Total Knee Replacement Coaching Program for Patients Preparing to Undergo Total Knee Arthroplasty, a Pilot Randomized Trial

    Noelia Hernandez1, Yuliana Dominguez Paez2, Assem Jabri2, Mackenzie Brown2, Geyanne Lui3, Wai-Kwong Hui4, Michael Parks4, Alejandro Gonzalez Della Valle4, Fred Cushner4, Peter Sculco4, Thomas Sculco4, Mathias Bostrom4, Alejandro Leali4, Jason Blevins4, Jose Rodriguez4, Gwo-Chin Lee4, Lisa Mandl5, Susan Goodman4, Samprit Banerjee2, Monika Safford6 and Iris Navarro-Millán7, 1Weill Cornell Medicine, The Bronx, NY, 2Weill Cornell Medicine, New York, NY, 3New York Institute of Technology, New York, NY, 4Hospital for Special Surgery, New York, NY, 5Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 6WCM Department of Medicine, New York, NY, 7Weill Cornell Medicine, Hospital for Special Surgery, New York, NY

    Background/Purpose: Up to 30% of patients with primary knee osteoarthritis (KOA) who have undergone Total Knee Replacement (TKR) continue to experience knee pain after surgery.High…
  • Abstract Number: 0306 • ACR Convergence 2023

    Fitbit Is a Valid and Reliable Physical Activity Monitor in Idiopathic Inflammatory Myopathy

    Akanksha Sharma1, shiri keret2, Raisa Lomanto Silva3, Tanya Chandra4, Joel Levin5, Siamak Moghadam-Kia3, Chester V. Oddis6 and Rohit Aggarwal6, 1UPMC Mercy Hospital, Pittsburgh, PA, 2Bnai Zion, Atlit, Israel, 3University of Pittsburgh Medical Center, Pittsburgh, PA, 4Georgetown University Hospital, Washington, DC, 5University of Pittsburgh, Katz Graduate School, Pittsburgh, PA, 6University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM, myositis) are a systemic autoimmune disease leading to debilitating muscle weakness and significant limitations in daily activities. Physical activity monitor…
  • Abstract Number: 2499 • ACR Convergence 2023

    Influence of Adiposity on Physical Function, Physical Activity, and Self-Reported Symptom Severity for Individuals with Arthritis Prior to Beginning a Physical Activity Promotion Intervention

    Scott Jamieson, Sara Wilcox and Christine Pellegrini, The University of South Carolina, Columbia, SC

    Background/Purpose: Engagement in moderate-vigorous physical activity (MVPA) is recommended for individuals with obesity to promote weight loss and mitigate severity of chronic diseases associated with…
  • Abstract Number: 0386 • ACR Convergence 2023

    Functional Disability and Disease Activity Are Affected by Social Determinants of Health in Patients with Rheumatoid Arthritis

    Mohammad Movahedi1, Kangping Cui2, George Tomilnson3, Angela Cesta3, xiuying Li3 and Claire Bombardier4, 1Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 2Sunnybrook Hospital, Toronto, ON, Canada, 3University Health Network, Toronto, ON, Canada, 4University of Toronto, Toronto, ON, Canada

    Background/Purpose: The relationship between social determinants of health (SDH) (e.g. income, education, and employment status) and disease outcomes in the RA population is not well…
  • Abstract Number: 2580 • ACR Convergence 2023

    High-intensity Resistance Training Improves Quality of Life, Muscle Endurance and Strength in Patients with Myositis

    Kasper Jensen1, Per Aagaard2, Charlotte Suetta3, Jakob Nielsen2, Rune Bech4, Henrik Schrøder1, Casper Simonsen1, Jan Christensen1 and Louise Pyndt Diederichsen5, 1University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark, 2University of Southern Denmark, Odense, Denmark, 3Bispebjerg Hospital, Copenhagen, Denmark, 4Zealand University Hospital, Koege, Dragør, Denmark, 5University Hospital of Copenhagen, Rigshospitalet, Dragør, Denmark

    Background/Purpose: Myositis is associated with muscle impairment, which impacts quality of life. The purpose of this study was to investigate the effects of high-intensity strength…
  • Abstract Number: 0526 • ACR Convergence 2023

    Bimekizumab Improved Physical Function and Health-Related Quality of Life in Patients with Axial Spondyloarthritis: 52-Week Results from Two Phase 3 Studies

    Maureen Dubreuil1, Karl Gaffney2, Jonathan Kay3, Victoria Navarro-Compán4, Christine de la Loge5, Alicia Ellis6, Carmen Fleurinck7, Ute Massow8, Vanessa Taieb9 and Atul Deodhar10, 1Department of Rheumatology, Boston University School of Medicine, Milton, MA, 2Norfolk and Norwich University Hospital NHS Trust, Norfolk, United Kingdom, 3Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA, 4Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 5UCB Pharma, Brussels, Belgium, 6UCB Pharma, Raleigh, NC, 7UCB Pharma, Oosterzele, Belgium, 8UCB Pharma, Monheim am Rhein, Germany, 9UCB Pharma, Colombes, France, 10Division of Arthritis and Rheumatic Disease, Oregon Health & Science University, Portland, OR

    Background/Purpose: Axial spondyloarthritis (axSpA) severely impairs physical function and health-related quality of life (HRQoL).1 Bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits IL-17F in…
  • Abstract Number: 2587 • ACR Convergence 2023

    Measuring Frailty in SLE: Agreement Among Methods

    Patti Katz1, Maria Dall'Era2, Kamil Barbour3, Kurt Greenlund3, Cristina Lanata4, Caroline Gordon5, Lindsey Criswell6 and Jinoos Yazdany7, 1University of California San Francisco, San Rafael, CA, 2University of California San Francisco, San Francisco, CA, 3Centers for Disease Control and Prevention, Atlanta, GA, 4National Human Genome Research Institute, Washington, DC, 5Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 6NIH/NHGRI, Bethesda, MD, 7University of California, General Department of Medicine, Division of Rheumatology, San Francisco, CA

    Background/Purpose: Frailty, conceptualized as an accumulation of deficits across multiple physiological systems, was first examined in SLE in 2017 using the Fried Frailty Phenotype criteria…
  • Abstract Number: 0620 • ACR Convergence 2023

    Physical and Mental Health in Early Systemic Sclerosis: Baseline Results for Patient-Reported Outcomes Measurement Information System-29 from the Collaborative National Quality and Efficacy Registry

    Isha Lamba1, Ashima Makol2, Dinesh Khanna3, John VanBuren4, Angela Child4, Jessica Alvey4, Shervin Assassi5, Elana Bernstein6, Flavia Castelino7, Lorinda Chung8, Luke Evnin9, Tracy Frech10, Faye Hant11, Laura Hummers12, Kimberly Lakin13, Dorota Lebiedz-Odrobina14, Yiming Luo15, Jerry Molitor16, Duncan Moore17, Carrie Richardson18, Nora Sandorfi19, Ami Shah20, Ankoor Shah21, Victoria Shanmugam22, Brian Skaug23, Virginia Steen24, Elizabeth Volkmann25 and Jessica Gordon13, 1New York Presbyterian Hospital/Weill Cornell Medical Centre, New York, NY, 2Mayo Clinic, Rochester, MN, Rochester, MN, 3University of Michigan, Ann Arbor, MI, 4University of Utah, Salt Lake City, UT, 5University of Texas McGovern Medical School at Houston, Houston, TX, 6Columbia University, New York, NY, 7Massachusetts General Hospital, Boston, MA, 8Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Woodside, CA, 9Scleroderma Research Foundation, Brisbane, CA, 10Vanderbilt University Medical Center, Nashville, TN, 11Medical University of South Carolina, Charleston, SC, 12Johns Hopkins University, Baltimore, MD, 13Hospital for Special Surgery, New York, NY, 14University of Utah, Cottonwood Heights, UT, 15Division of Rheumatology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, 16University of Minnesota, Minneapolis, MN, 17Northwestern Memorial Hospital, Chicago, IL, 18Northwestern University, Riverside, IL, 19University of Pennsylvania, Philadelphia, PA, 20Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Ellicott City, MD, 21Duke University, Durham, NC, 22Victoria Shanmugam, MD, Great Falls, VA, 23Division of Rheumatology, University of Texas McGovern Medical School, Houston, TX, 24Georgetown University School of Medicine, Washington, DC, 25University of California Los Angeles, Los Angeles, CA

    Background/Purpose: Patient-Reported Outcomes Measurement Information System-29 version 2.0 (PROMIS-29v2) is a patient-centered questionnaire used to assess health-related quality of life (HRQoL). PROMIS-29v2 has shown validity…
  • Abstract Number: 0629 • ACR Convergence 2023

    Negative Affect, Anxiety and Fatigue Moderate the Association Between Pain Intensity and Physical Function in People with Systemic Sclerosis

    Daniel Whibley1, Yen Chen1, Anna Kratz1, Dinesh Khanna1 and Susan Murphy2, 1University of Michigan, Ann Arbor, MI, 2University of Michigan, Plymouth, MI

    Background/Purpose: Pain is a common symptom of systemic sclerosis (SSc), affecting over 80% of those living with the condition, with over a third experiencing pain…
  • Abstract Number: 0990 • ACR Convergence 2023

    Association of Treatment and Disease Activity with Antibiotic Use and Hospitalized Infection Among People Living with Rheumatoid Arthritis: Baseline Data from a Longitudinal Study in the ArthritisPower Registry

    Kelly Gavigan1, Esteban Rivera2, Odette Kolenky3, Cassie Clinton4, Emily Holladay4, David Curtis5, Laura Stradford6, Jeffrey Curtis4, W. Benjamin Nowell6, Christian Curtis7 and Michael George8, 1Global Healthy Living Foundation, Upper Nyack, NY, 2Global Healthy Living Foundation, Long Island City, NY, 3Hospital of the University of Pennsylvania, Philadelphia, PA, 4University of Alabama at Birmingham, Birmingham, AL, 5Global Healthy Living Foundation, San Francisco, CA, 6Global Healthy Living Foundation, Nyack, NY, 7Illumination Health, Birmingham, AL, 8University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Infections are a major contributor to morbidity and mortality in patients (pts) with rheumatoid arthritis (RA). Little is known about the risk of non-serious…
  • Abstract Number: 1277 • ACR Convergence 2023

    Relationship Between Quality of Life and the Region of the Affected Joints in Japanese Patients with Rheumatoid Arthritis: A Cross-sectional Study

    Kenichiro Tokunaga1, Takahiro Nishino2, Hideto Oshikawa1, Toshihiro Matsui3 and Shigeto Tohma4, 1Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 2National Hospital Organization Sagamihara National Hospital, Kanagawa, Japan, 3NHO Sagamihara National Hospital, Kanagawa, Japan, 4NHO Tokyo National Hospital, Dallas, TX

    Background/Purpose: This clinical study aimed to investigate the relationship between affected joints and the quality of life (QOL) in patients with rheumatoid arthritis (RA) in…
  • Abstract Number: 1278 • ACR Convergence 2023

    Nature and Severity of Activity Limitations According to the Health Assessment Questionnaire Disability Index in Patients with Rheumatoid Arthritis and Functional Disability

    Manja van Wissen1, Maaike gademan1, Cornelia van den Ende2, Max Teuwen1, Wilfred Peter1, Dirkjan van Schaardenburg3, Alfons den Broeder2, Thea Vliet Vlieland4 and Salima van Weely1, 1Leiden University Medical Center, Leiden, Netherlands, 2Sint Maartenskliniek, Nijmegen, Netherlands, 3Reade, Amsterdam, Netherlands, 4Leids University Medical Center, Leiden, Netherlands

    Background/Purpose: Not withstanding modern treatment, some Rheumatoid Arthritis (RA) patients have severe disability due to persistently high disease activity, joint destruction/deformities and/or comorbidities. Insight into…
  • Abstract Number: 1279 • ACR Convergence 2023

    What Is the Nature of Functional Problems in People with Rheumatoid Arthritis and Severe Disability; An Analysis Using the International Classification of Functioning, Disability and Health as a Reference

    Max Teuwen1, Salima van Weely1, Thea Vliet Vlieland2, Thom Douw3, Manja van Wissen1, Alfons den Broeder4, Dirkjan van Schaardenburg5, Cornelia van den Ende4 and Maaike gademan1, 1Leiden University Medical Center, Leiden, Netherlands, 2Leids University Medical Center, Leiden, Netherlands, 3Leiden University of Applied Sciences, Leiden, Netherlands, 4Sint Maartenskliniek, Nijmegen, Netherlands, 5Reade, Amsterdam, Netherlands

    Background/Purpose: There is a lack of knowledge about the limitations in activities and participation experienced by a subgroup of people with rheumatoid arthritis (RA) and…
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