Abstracts tagged "physical function"

Abstract Number: 0518 • ACR Convergence 2024
Sustained Patient Meaningful Outcomes of Pain and Fatigue Relief and Improved Physical Functioning with Filgotinib in Rheumatoid Arthritis: A Post Hoc Analysis
Rieke Alten¹, Bruno Fautrel², Philip G Conaghan³, Dick de Vries⁴, Margaux Faes⁵, Mercedes Piovesan⁶, Katrien Van Beneden⁷, Chris Watson⁸, Angelique E.A.M. Weel-Koenders⁹, Eugen Feist¹⁰ and Kurt de Vlam¹¹, ¹Department of Internal Medicine and Rheumatology, Schlosspark Klinik, University Medicine Berlin, Berlin, Germany, ²INSERM, UMRS 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Sorbonne University – Assistance Publique-Hôpitaux de Paris, Département de Rhumatologie, Hôpital Pitié-Salpêtrière, Paris, Ile-de-France, France, ³Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ⁴Clinical Development, Galapagos BV, Leiden, Netherlands, ⁵Biostatistics, Galapagos NV, Mechelen, Belgium, ⁶Medical Affairs, Galapagos Biopharma Spain SLU, Madrid, Spain, ⁷Medical Affairs, Galapagos NV, Mechelen, Belgium, ⁸Medical Affairs, Galapagos Biotech Ltd, Cambridge, United Kingdom, ⁹Erasmus School of Health Policy and Management, Erasmus University Rotterdam, and Department of Rheumatology and Clinical Immunology, Maasstad Hospital, Rotterdam, Netherlands, ¹⁰Department of Rheumatology, Helios Clinic Vogelsang-Gommern, cooperation partner of the Otto von Guericke University Magdeburg, Gommern, Germany, ¹¹Department of Rheumatology, UZ Leuven, and Department of Development and Regeneration, Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium
Background/Purpose: Quality of life for patients with RA can be severely impacted by pain, fatigue and impaired physical functioning.1 Filgotinib (FIL) has demonstrated early onset…
Abstract Number: 0680 • ACR Convergence 2024
Clinical Correlates of Physical and Mental Health in Early Systemic Sclerosis: Data from the Collaborative National Quality and Efficacy (CONQUER) Registry
Ashima Makol¹, Isha Lamba², Dinesh Khanna³, John VanBuren⁴, Angela Child⁴, Jessica Alvey⁴, Shervin Assassi⁵, Elana Bernstein⁶, Flavia Castelino⁷, Lorinda Chung⁸, Luke Evnin⁹, Tracy Frech¹⁰, Faye Hant¹¹, Laura Hummers¹², Kimberly Lakin¹³, Dorota Lebiedz-Odrobina¹⁴, Yiming Luo¹⁵, Jerry Molitor¹⁶, Duncan Moore¹⁷, Carrie Richardson¹⁸, Nora Sandorfi¹⁹, Ami Shah²⁰, Ankoor Shah²¹, Brian Skaug⁵, Virginia Steen²², Elizabeth Volkmann²³ and Jessica Gordon²⁴, ¹Mayo Clinic, Rochester, MN, Rochester, MN, ²New York Presbyterian Hospital/Weill Cornell Medical Centre, New York, NY, ³University of Michigan, Ann Arbor, MI, ⁴University of Utah, Salt Lake City, UT, ⁵UTHealth Houston Division of Rheumatology, Houston, TX, ⁶Division of Rheumatology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, ⁷Massachusetts General Hospital, Boston, MA, ⁸Stanford University, Woodside, CA, ⁹Scleroderma Research Foundation, Brisbane, CA, ¹⁰Vanderbilt University Medical Center, Nashville, TN, ¹¹Medical University of South Carolina, Charleston, SC, ¹²Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Ellicott City, MD, ¹³Hospital for Special Surgery, New York, NY, ¹⁴University of Utah, Cottonwood Heights, UT, ¹⁵Columbia University, New York, NY, ¹⁶University of Minnesota, Minneapolis, MN, ¹⁷Northwestern Memorial Hospital, Chicago, IL, ¹⁸Northwestern University, Chicago, IL, ¹⁹University of Pennsylvania, Philadelphia, PA, ²⁰Division of Rheumatology, Johns Hopkins University, Ellicott City, MD, ²¹Duke University, Durham, NC, ²²Georgetown University School of Medicine, Washington, DC, ²³University of California, Department of Medicine, Los Angeles, CA, USA, Los Angeles, ²⁴Division of Rheumatology, Weill Cornell Medical College, New York, NY
Background/Purpose: Early years of Systemic sclerosis (SSc) are typically the period of peak disease activity and associated with greater pain, fatigue, sleep disturbance, physical impairment,…
Abstract Number: 1228 • ACR Convergence 2024
Central Pain Mechanisms and Physical Function in Early Rheumatoid Arthritis
Burcu Aydemir¹, Lutfiyya Muhammad², Jing Song³, Dorothy Dunlop⁴, Kathleen Aren⁵, Mary Carns⁵, Wendy Marder⁶, Vivian Bykerk⁷, Kevin Deane⁸, Clifton Bingham⁹ and Yvonne Lee¹, ¹Northwestern University, Chicago, IL, ²Northwestern Feinberg School of Medicine, Chicago, IL, ³Northwestern University, Worthington, MN, ⁴Northwestern University, New Haven, CT, ⁵Northwestern University Division of Rheumatology, Chicago, IL, ⁶University of Michigan, Ann Arbor, MI, ⁷Hospital For Special Surgery, New York, NY, ⁸University of Colorado Denver Anschutz Medical Campus, Aurora, CO, ⁹Johns Hopkins University, Baltimore, MD
Background/Purpose: Despite effective control of inflammation, patients with rheumatoid arthritis (RA) may experience lingering pain and losses in physical function. Pain can occur because central…
Abstract Number: 1670 • ACR Convergence 2024
Predictors of 6-Minute Walk Test Performance in Adults with Arthritis
Kailyn Horn, Scott Jamieson, Katherine Devivo, Sara Wilcox, Yesil Kim, Chih-Hsiang Yang and Christine Pellegrini, University of South Carolina, Columbia, SC
Background/Purpose: The 6-Minute Walk Test (6MWT) is a measure commonly used by clinicians to assess functional capacity and rehabilitation progress. While predictors of 6MWT performance…
Abstract Number: 2571 • ACR Convergence 2024
Trajectories of Physical Function in Children with Juvenile Idiopathic Arthritis: Results from the CAPRI Registry
Clare Cunningham¹, Roberta A Berard², Matthew Berkowitz³, Brian Feldman⁴, Nicole Johnson⁵, Lillian Lim⁶, Thomas Loughin³, Meghan McPherson⁷, Paivi Miettunen⁵, Jean-Philippe Proulx-Gauthier⁸, Dax Rumsey⁶, Heinrike Schmeling⁵, Lori Tucker⁹, Kristin Houghton¹⁰ and Jaime Guzman¹¹, and CAPRI Registry Investigators, ¹University of British Columbia, Vancouver, BC, Canada, ²London Health Sciences Centre, London, ON, Canada, ³Simon Fraser University, Burnaby, BC, Canada, ⁴Division of Rheumatology, The Hospital for Sick Children; Departments of Pediatrics and Medicine, Faculty of Medicine; The Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ⁵University of Calgary, Calgary, AB, Canada, ⁶University of Alberta, Edmonton, AB, Canada, ⁷University of Manitoba, Winnipeg, MB, Canada, ⁸CHU de Quebec - Universite Laval, Quebec, QC, Canada, ⁹BC Children's Hospital, Vancouver, BC, Canada, ¹⁰University of British Columbia - Vancouver, Vancouver, BC, Canada, ¹¹University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada
Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood. Contrary to historical cohorts, it is hoped that with contemporary treatments…
Abstract Number: 0170 • ACR Convergence 2024
Association of General Physical Functioning, Valued Life Activity (VLA) Disability, and Use of Accommodations with Depressive Symptoms Among Individuals with Systemic Lupus Erythematosus (SLE)
Patti Katz¹, Laura Plantinga², Maria Dall'Era³, Kamil Barbour⁴, Kurt Greenlund⁴ and Jinoos Yazdany⁵, ¹UCSF, San Rafael, CA, ²University of California, San Francisco, San Francisco, CA, ³UCSF, Corte Madera, CA, ⁴CDC, Alpharetta, GA, ⁵University of California San Francisco, San Francisco, CA
Background/Purpose: Physical functioning (PF) is usually assessed generally in SLE rather than as difficulty performing specific activities, and measurements rarely incorporate accommodations (ACCs) that may…
Abstract Number: 0175 • ACR Convergence 2024
Do Knee Strength and Pain Relate to Developing Stair Climbing Difficulty for Knee Osteoarthritis?
Jason Jakiela¹, Yvonne Golightly², Sydney Liles³, Judy Foxworth⁴ and Daniel White⁵, ¹Winston-Salem State University, Winston-Salem, NC, ²University of Nebraska Medical Center, Omaha, NE, ³University of Delaware, Elkton, MD, ⁴Winston-Salem State University, Elon, NC, ⁵University of Delaware, Newark, DE
Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation in older adults, and stair climbing difficulty is often the first-reported limitation. Previous work…
Abstract Number: 0190 • ACR Convergence 2024
Socioeconomic Disparities in Functional Status by Neighborhood Deprivation in a National Sample of Patients with Systemic Lupus Erythematosus
Baljeet Rai¹, Jessica Fitzpatrick², Jing Li³, Gabriela Schmajuk⁴ and Jinoos Yazdany⁵, ¹University of California, San Francisco, Modesto, CA, ²University California, San Francisco, San Francisco, CA, ³University of California, San Francisco, San Francisco, CA, ⁴UCSF / SFVA, San Francisco, CA, ⁵University of California San Francisco, San Francisco, CA
Background/Purpose: Individuals with SLE can experience significant declines in functional status (FS). The ACR has recently identified physical function as a high-priority domain in SLE…
Abstract Number: 1277 • ACR Convergence 2023
Relationship Between Quality of Life and the Region of the Affected Joints in Japanese Patients with Rheumatoid Arthritis: A Cross-sectional Study
Kenichiro Tokunaga¹, Takahiro Nishino², Hideto Oshikawa¹, Toshihiro Matsui³ and Shigeto Tohma⁴, ¹Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, ²National Hospital Organization Sagamihara National Hospital, Kanagawa, Japan, ³NHO Sagamihara National Hospital, Kanagawa, Japan, ⁴NHO Tokyo National Hospital, Dallas, TX
Background/Purpose: This clinical study aimed to investigate the relationship between affected joints and the quality of life (QOL) in patients with rheumatoid arthritis (RA) in…
Abstract Number: 1278 • ACR Convergence 2023
Nature and Severity of Activity Limitations According to the Health Assessment Questionnaire Disability Index in Patients with Rheumatoid Arthritis and Functional Disability
Manja van Wissen¹, Maaike gademan¹, Cornelia van den Ende², Max Teuwen¹, Wilfred Peter¹, Dirkjan van Schaardenburg³, Alfons den Broeder², Thea Vliet Vlieland⁴ and Salima van Weely¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Sint Maartenskliniek, Nijmegen, Netherlands, ³Reade, Amsterdam, Netherlands, ⁴Leids University Medical Center, Leiden, Netherlands
Background/Purpose: Not withstanding modern treatment, some Rheumatoid Arthritis (RA) patients have severe disability due to persistently high disease activity, joint destruction/deformities and/or comorbidities. Insight into…
Abstract Number: 1279 • ACR Convergence 2023
What Is the Nature of Functional Problems in People with Rheumatoid Arthritis and Severe Disability; An Analysis Using the International Classification of Functioning, Disability and Health as a Reference
Max Teuwen¹, Salima van Weely¹, Thea Vliet Vlieland², Thom Douw³, Manja van Wissen¹, Alfons den Broeder⁴, Dirkjan van Schaardenburg⁵, Cornelia van den Ende⁴ and Maaike gademan¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Leids University Medical Center, Leiden, Netherlands, ³Leiden University of Applied Sciences, Leiden, Netherlands, ⁴Sint Maartenskliniek, Nijmegen, Netherlands, ⁵Reade, Amsterdam, Netherlands
Background/Purpose: There is a lack of knowledge about the limitations in activities and participation experienced by a subgroup of people with rheumatoid arthritis (RA) and…
Abstract Number: 1293 • ACR Convergence 2023
Single Camera Hand Motion Capturing as a Digital Biomarker for Disease Activity in Rheumatoid Arthritis Using Computer Vision: The Proof-of-Concept MeFisto Study
Vincenzo Venerito¹, Tobias Maningold², Deborah Markham³, Marc Blanchard⁴, Florenzo Iannone¹ and Thomas Hügle⁵, ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", Bari, Italy, ²Department of Rheumatology, University Hospital Bern (Inselspital), University Bern, Bern, Switzerland, ³on behalf of Department Rheumatology, University Hospital Lausanne, Lausanne, Switzerland, ⁴Dept. of Rheumatology, University Hospital Lausanne (CHUV) and University Lausanne, Lausanne, Switzerland, ⁵Dept. of Rheumatology, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland
Background/Purpose: Computer vision technology offerspromising possibilities for remotely assessing disease activity in rheumatoid arthritis (RA) patients, enabling telemedicine and improving access to care. The objective…
Abstract Number: 1444 • ACR Convergence 2023
Identifying Determinants of Favourable and Poor Physical Function in Systemic Lupus Erythematosus: Results from an International Collaborative Study
Sook Yan Lee¹, Amelia Holloway², Elena Nikiphorou³, Ioannis Parodis⁴, Naveen R⁵, Jessica Day⁶, Mrudula Joshi⁷, Sreoshy Saha⁸, Kshitij Jagtap⁹, Wanruchada Katchamart¹⁰, Phonpen Akarawatcharangura Goo¹¹, Binit Vaidya¹², Tsvetelina Velikova¹³, Parikshit Sen¹⁴, Samuel Shinjo¹⁵, Vishwesh Agarwal¹⁶, Ai Lyn Tan¹⁷, Nelly Ziade¹⁸, Marcin Milchert¹⁹, Abraham Edgar Gracia-Ramos²⁰, Carlo Caballero²¹, COVAD Study Group²², Hector Chinoy²³, Vikas Agarwal⁵, Rohit Aggarwal²⁴, Latika Gupta²⁵ and Chris Wincup², ¹King's College Hospital, London, United Kingdom, ²King's College Hospital, London, United Kingdom, ³King's College London, London, United Kingdom, ⁴Karolinska Institutet, Stockholm, Sweden, ⁵Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, ⁶Walter and Eliza Hall Institute, Melbourne, Australia, ⁷Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, ⁸Mymensingh Medical College, Faridpur, Bangladesh, ⁹Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, ¹⁰Mahidol University, Bangkok, Thailand, ¹¹Department of Medicine, Queen Savang Vadhana Memorial Hospital, Chonburi, Thailand, ¹²National Centre for Rheumatic Diseases, Kathmandu, Nepal, ¹³Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria, ¹⁴Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, ¹⁵Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, ¹⁶Mahatma Gandhi Missions Medical College, Lucknow, India, ¹⁷University of Leeds, Leeds, United Kingdom, ¹⁸Saint-Joseph University, Beirut, Lebanon, ¹⁹Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, ²⁰Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico, ²¹Universidad del Norte, Barranquilla, Colombia, ²²-, -, ²³The University of Manchester, Sale, United Kingdom, ²⁴University of Pittsburgh, Pittsburgh, PA, ²⁵Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom
Background/Purpose: Systemic lupus erythematosus (SLE) can result in impaired daily physical function through various mechanisms including active disease, chronic damage, and mental health symptoms that…
Abstract Number: 1653 • ACR Convergence 2023
Up or Down: Does Direction of Stair Climbing Difficulty Matter for Incident Functional Limitation and Knee Replacement in Knee Osteoarthritis?
Jason Jakiela¹, Thomas Bye¹, Sydney Liles² and Daniel White¹, ¹University of Delaware, Newark, DE, ²University of Delaware, Elkton, MD
Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation (FL) in older adults, with difficulty climbing stairs often the first-reported limitation. Overall increased…
Abstract Number: 0020 • ACR Convergence 2023
The Inflammatory Proteome in Sjögren’s Syndrome Identifies New Biomarkers and Relevant Clinical Subgroups
José Miguel Sequí-Sabater¹, Carlos Perez-Sanchez², Clarissa Meoni³, Tomás Cerdó-Ráez⁴, Maria del Carmen Abalos-Aguilera⁵, Desiree Ruiz Vilchez⁵, Francisco Cepas⁴, Nuria Barbarroja⁶, Alejandro Escudero⁷, Mª Angeles Aguirre⁸, Chary Lopez-Pedrera⁹ and Lorenzo Beretta¹⁰, ¹Agencia Valenciana de Salut/ Hospital Universitari de la Ribera/ Unitat de Reumatología, Gandía, Spain, ²IMIBIC, Córdoba, Spain, ³Ospedale Policlinico di Milano, Milan, Italy, ⁴Maimonides Institute for Biomedical Research (IMIBIC), Córdoba, Spain, ⁵Rheumatology Department, Reina Sofia University Hospital/Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Córdoba, Spain, ⁶University of Cordoba, Córdoba, Spain, ⁷SAS, Córdoba, Spain, ⁸Reina Sofía University Hospital/ Rheumatology Department, Córdoba, Spain, ⁹IMIBIC - Reina Sofia Hospital, Córdoba, Spain, ¹⁰Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di MIlano, Milan, Italy
Background/Purpose: Primary Sjögren's syndrome (pSS) is an autoimmune disease characterised by glandular involvement of the eye and salivary glands, leading to xerostomia and xerophthalmia. In…

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