Abstracts tagged "Osteoarthritis"

Abstract Number: 400 • 2018 ACR/ARHP Annual Meeting
Predictors of Response to a Single Intra-Articular Injection of Mannitol-Modified Cross-Linked Hyaluronic Acid (HANOX-M-XL) in Patients with First Metatarsophalangeal Joint Osteoarthritis (hallux rigidus)
Thierry Conrozier¹, Aline Charpentier², Marie Bossert³, Sylvie Mellac-Ducamp⁴ and Laurent Galois⁵, ¹Department of Rheumatology,, Nord Franche-Comté Hospital, Belfort, France, ²Rheumatology, Nord Franche-Comté Hospital, Belfort, France, ³Rheumatology, Nord Franche Comté Hospital, Belfort, France, ⁴Rheumatology, Nevers General Hospital, Nevers, France, ⁵Orthopaedic and trauma surgery, University Hospital of Nancy, Nancy, France
Background/Purpose: To investigate the potential predictors of response to a single intra-articular injection of mannitol-modified cross-linked hyaluronic acid (HANOX-M-XL) in patients with first metatarsophalangeal joint…
Abstract Number: 1052 • 2018 ACR/ARHP Annual Meeting
Detection of Precursors of RANK- Osteoclast-like Cells (Olcs) in Peripheral Blood and Olcs in Bone Tissue from Rheumatoid Arthritis Patients
Kazuhiro Yokota¹, Shinya Tanaka², Miyoko Sekikawa², Yoshimi Aizaki¹, Kojiro Sato¹, Hiromi Oda² and Toshihide Mimura¹, ¹Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, ²Department of Orthopaedic Surgery, Saitama Medical University, Saitama, Japan
Background/Purpose: Proinflammatory cytokines play an important role in bone destruction in rheumatoid arthritis (RA), as inferred by the efficacy of biologics. Previously, we reported that…
Abstract Number: 1395 • 2018 ACR/ARHP Annual Meeting
Could the Shortening of the Electronic Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) Questionnaire Improve Its Metric Properties?
Maud Wieczorek¹, Christine Rotonda¹, Jonathan Epstein^1,2, Francis Guillemin^1,2 and Anne-Christine Rat^1,3, ¹Université de Lorraine, EA4360, APEMAC, Nancy, France, ²Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ³Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: The aim of this study was to assess the validity of a short version of the electronic OAKHQOL questionnaire in a combined analysis with…
Abstract Number: 405 • 2018 ACR/ARHP Annual Meeting
Feasibility of Enabling Self-Management and Coping with Arthritic Pain Using Exercise (ESCAPE-Pain) Programme for Knee Osteoarthritis in Malaysia
Muhammad Kamil Che Hasan^1,2, Emma Stanmore² and Chris Todd², ¹Kulliyyah (Faculty) of Nursing, International Islamic University Malaysia (IIUM), Kuantan Pahang, Malaysia, ²Division of Nursing, Midwifery and Social Work, The University of Manchester, Manchester, United Kingdom
Background/Purpose: In Malaysia around one in ten older people are diagnosed with osteoarthritis (OA), with the knee being one of the most commonly affected areas.…
Abstract Number: 1137 • 2018 ACR/ARHP Annual Meeting
Prediction Models for Poor Function Outcomes over 10 Years in Persons at High Risk for Knee Osteoarthritis
Leena Sharma¹, Orit Almagor¹, Alison H. Chang¹, C. Kent Kwoh², Michael C. Nevitt³, Marc C. Hochberg⁴, Rebecca D. Jackson⁵, Charles B. Eaton⁶, Jane A. Cauley⁷, Julie Szymaszek⁸ and Joan S. Chmiel¹, ¹Northwestern University, Chicago, IL, ²University of Arizona, Tucson, AZ, ³UCSF, San Francisco, CA, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Ohio State University, Columbus, OH, ⁶Family Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI, ⁷University of Pittsburgh, PIttsburgh, PA, ⁸Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Among persons at high risk for knee osteoarthritis (OA), identifying those who will have function decline is important; instituting prevention strategies in all…
Abstract Number: 1443 • 2018 ACR/ARHP Annual Meeting
Ultrasonographic Criteria for the Diagnosis of Erosive Rheumatoid Arthritis Disease Using Osteoarthritic Patients As Controls Compared to Validated Radiographic Criteria
Camille Roux¹, Frédérique Gandjbakhch², Audrey Pierreisnard³, Marion Couderc⁴, Cédric Lukas⁵, Racha Masri¹, Jean-Philippe Sommier¹, Isabelle Clerc-Urmès⁶, Cedric Baumann⁷, Isabelle Chary-Valckenaere⁸ and Damien Loeuille⁹, ¹Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, ²UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ³APHP, Paris, France, ⁴Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France, ⁵Rheumatology, Lapeyronie Hospital and EA2415 Montpellier University, Montpellier, France, ⁶CHRU Nancy, Nancy, France, ⁷CHRU Nancy, Vandoeuvre les Nancy, France, ⁸Rheumatology, CHRU Nancy, Vandoeuvres les Nancy, France, ⁹Rheumatology, University Hospital of Nancy, NANCY, France
Background/Purpose: Rheumatoid arthritis (RA) is the most prevalent chronic inflammatory joint disease (1,2) responsible for structural damage. Radiography (RX) is considered as the gold standard…
Abstract Number: 406 • 2018 ACR/ARHP Annual Meeting
Limiting the Risk of Osteoarthritis after Anterior Cruciate Ligament Injury: Are We Missing the Opportunity to Intervene?
Aileen Davis¹, Rosalind Wong², Krista Steinhart², Janie Astephen Wilson³, Laura Cruz⁴, David Cudmore³, Tim Dwyer⁵, Linda Li⁶, Peter MacDonald⁷, Paul Marks⁴, Laura Nimmon⁸, Darrell Ogilvie-Harris⁴, Nathan Urquhart³ and Jas Chahal⁵, ¹Health Care and Outcomes Research, Krembil Research Institute, University Health Network, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, ²Krembil Research Institute, Health Care and Outcomes Research, Toronto, ON, Canada, ³Dalhousie University, Halifax, NS, Canada, ⁴University of Toronto, Toronto, ON, Canada, ⁵Orthopaedics, University of Toronto, Toronto, ON, Canada, ⁶Arthritis Research Canada, Richmond, BC, Canada, ⁷Pan Am Clinic, Winnipeg, ON, Canada, ⁸University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Fifty percent of people with anterior cruciate (ACL) injury develop knee osteoarthritis (OA) within 6-10 years, even with ligament reconstruction. Despite evidence that targeted…
Abstract Number: 1138 • 2018 ACR/ARHP Annual Meeting
Public Health Impact of Physical Inactivity in the Knee OA Population in the US
Elena Losina¹, Genevieve S. Silva², Karen C. Smith², Jamie E. Collins³, David J. Hunter⁴, Swastina Shrestha², Stephen P. Messier⁵, Edward H. Yelin⁶, Lisa Gale Suter⁷, A. David Paltiel⁸ and Jeffrey N. Katz⁹, ¹Orthopedics, Brigham and Women's Hospital, BU School of Public Health and Harvard Medical School, Boston, MA, ²Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ³Department of Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁵Department of Health and Exerc, Wake Forest University, Winston-Salem, NC, ⁶Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ⁷Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT, ⁸Yale University, New Haven, CT, ⁹Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: The benefits of physical activity (PA) in persons with OA are well-documented: PA reduces OA pain, improves mental health, and reduces the risk of…
Abstract Number: 1444 • 2018 ACR/ARHP Annual Meeting
Optimization of Ultrasonographic Examination for the Diagnosis of Erosive Rheumatoid Arthritis Versus Erosive Osteoarthritis with Radiography Considered As Gold Standard
Camille Roux¹, Frédérique Gandjbakhch², Audrey Pierreisnard³, Marion Couderc⁴, Cédric Lukas⁵, Racha Masri¹, Jean-Philippe Sommier¹, Isabelle Clerc-Urmès⁶, Cedric Baumann⁷, Isabelle Chary-Valckenaere⁸ and Damien Loeuille¹, ¹Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, ²UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ³APHP, Paris, France, ⁴Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France, ⁵Rheumatology, CHU Lapeyronie and EA2415, Montpellier University, University of Montpellier, France, ⁶CHRU Nancy, Nancy, France, ⁷CHRU Nancy, Vandoeuvre les Nancy, France, ⁸Rheumatology, CHRU Nancy, Vandoeuvres les Nancy, France
Background/Purpose: Rheumatoid arthritis (RA) is the most prevalent chronic inflammatory joint disease (1,2) responsible for structural damage. Radiography (RX) is considered as the gold standard…
Abstract Number: 411 • 2018 ACR/ARHP Annual Meeting
Kinesiophobia and Physical Function Among Adults with Knee Osteoarthritis: Before and after Strength Training Classes
Aileen Ledingham¹, Michael P. LaValley², Kristin Baker³ and Julie Keysor⁴, ¹Boston University, Boston, MA, ²Biostatistics, Boston University School of Public Health, Boston, MA, ³Franklin Pierce University, Rindge, NH, ⁴Physical Therapy, MGH Institute of Health Professions, Boston, MA
Background/Purpose: Approximately 14 million people in the United States have been clinically diagnosed with symptomatic knee OA. Rising from a chair, negotiating stairs and walking…
Abstract Number: 1163 • 2018 ACR/ARHP Annual Meeting
Patterns of Depressive Symptoms before and after Surgery for Hip, Knee and Lumbar Spine Osteoarthritis
J. Denise Power, Prtha Kudesia, Alina Nadeem, Anthony V. Perruccio, Y. Raja Rampersaud, Nizar Mahomed and Rajiv Gandhi, Arthritis Program, Krembil Research Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: Although pain and decreased function are the primary symptom targets of OA surgeries, OA is also associated with depression. The impact of surgery on…
Abstract Number: 1922 • 2018 ACR/ARHP Annual Meeting
Characterization of the Pharmacology and Pharmacokinetics of Cntx-4975, a High-Purity, Synthetic Trans-Capsaicin in Clinical Development for the Treatment of Moderate to Severe OA Knee Pain
James Campbell, Randall Stevens and Peter Hanson, Centrexion Therapeutics, Boston, MA
Background/Purpose: CNTX-4975, a highly purified, synthetic trans-capsaicin and long-acting, non-opioid analgesic in phase 3 trials for moderate to severe OA knee pain, has demonstrated safety…
Abstract Number: 424 • 2018 ACR/ARHP Annual Meeting
Occult Extractable Synovial Fluid in Inflammatory and Non-Inflammatory Arthritis of the Knee
Noelle Rolle¹, Irum Jan², Wilmer Sibbitt Jr.¹, Philip Band³, William Hayward⁴, Maheswari Muruganandam¹, N. Suzanne Emil¹, Monthida Fangtham¹, Roderick Fields¹ and Arthur Bankhurst¹, ¹Rheumatology, University of New Mexico Health Sciences Center, Albuquerque, NM, ²Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, ³NYU School of Medicine, New York, NY, ⁴The Department of Exercise and Sport Sciences, New Mexico Highlands University, Las Vegas, NM
Background/Purpose: We hypothesized that mechanical compression of the knee in rheumatoid arthritis (RA) and osteoarthritis (OA) would mobilize occult extractable fluid and improve arthrocentesis success.Methods:…
Abstract Number: 1165 • 2018 ACR/ARHP Annual Meeting
Restless Sleep Trajectories over 8 Years: Data from the Osteoarthritis Initiative
Jing Song¹, Julia (Jungwha) Lee¹, Yvonne C. Lee², Alison H. Chang¹, Pamela Semanik³, Linda S. Ehrlich-Jones¹, Rowland W. Chang¹ and Dorothy D. Dunlop¹, ¹Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³College of Nursing, Rush University, Chicago, IL
Background/Purpose: Sleep disturbance has been recognized as a major public health issue. Evidence has shown that individuals with osteoarthritis (OA) are more likely to have…
Abstract Number: 1947 • 2018 ACR/ARHP Annual Meeting
Do Changes in Pain Sensitization and Depressive Symptoms Mediate the Effect of Extreme Weight Loss on Knee Pain Improvement?
S. Reza Jafarzadeh¹, Tuhina Neogi¹, Joshua J. Stefanik², Margaret M. Clancy¹, Jing-Sheng Li³ and David T. Felson¹, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Department of Physical Therapy, University of Delaware, Newark, DE, ³College of Health and Rehabilitation Sciences: Sargent College, Boston University, Boston, MA
Background/Purpose: We previously showed that the one-year effects of weight loss on knee pain reduction were not mediated by changes in structural features of osteoarthritis…

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