Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 2019 • 2019 ACR/ARP Annual Meeting
Tenosynovitis at the Metatarsophalangeal Joints, a Novel Feature of RA: Results from an Anatomical and Large Magnetic Resonance Imaging Study of Tendon Sheaths of the Forefoot
Yousra Dakkak¹, Friso Jansen ¹, Marco DeRuiter ¹, Monique Reijnierse ¹ and Annette van der Helm-van Mil ², ¹Leiden University Medical Center, Leiden, Netherlands, ²LUMC, Leiden, Zuid-Holland, Netherlands
Background/Purpose: Recent magnetic resonance imaging (MRI)-studies revealed that tenosynovitis in the hands is associated with rheumatoid arthritis (RA). Although the forefoot is a preferential location…
Abstract Number: 1162 • 2019 ACR/ARP Annual Meeting
Changes in Novel Composite Scores of Disease Activity and Cumulative Damage Are Prognostic of Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Matthew Harkey¹, Julie Davis ², Bing Lu ³, Lori Lyn Price ⁴, Robert Ward ⁵, James MacKay ⁶, Charles Eaton ⁷, Grace Lo ⁸, Mary Barbe ⁹, Ming Zhang ⁵, Jincheng Pang ¹⁰, Alina Stout ¹¹, Lavalley Michael ¹², Timothy McAlindon ¹³ and Jeffrey Driban ¹³, ¹University of Massachusetts Medical School, Worcester, ²George Washington University, Washington DC, ³Brigham and Women's Hospital, Boston, MA, ⁴Tufts Medical Center, Tufts University, Boston, MA, ⁵Tufts Medical Center, Boston, ⁶University of Cambridge, Cambridge, United Kingdom, ⁷Brown University Center for Primary Care and Prevention, Pawtucket, ⁸Center of Excellence Michael E. DeBakey VAMC, Baylor College of Medicine, Houston, TX, ⁹Temple University, Philadelphia, ¹⁰Pfizer, Inc., Cambridge, MA, ¹¹Northeastern University, Boston, ¹²Boston University, Boston, ¹³Tufts Medical Center, Boston, MA
Background/Purpose: Composite imaging scores that reflect cartilage damage, bone marrow lesions (BMLs), and effusion-synovitis may enable us to conceptualize knee osteoarthritis (KOA) disease progression as…
Abstract Number: 2185 • 2019 ACR/ARP Annual Meeting
MRI-detected Abnormalities in Prediction Models of Incident Radiographic Knee Osteoarthritis over 10 Years of Follow-up
C. Kent Kwoh¹, Frank Roemer ², Erin Ashbeck ³, ChengCheng Hu ¹, Edward Bedrick ¹, Leena Sharma ⁴ and Ali Guermazi ⁵, ¹University of Arizona, Tucson, AZ, ²University of Erlangen-Nuremberg, Erlangen, Germany, ³The University of Arizona Arthritis Center, University of Arizona, Tuccson, AZ, Tucson, AL, ⁴Northwestern University, Chicago, IL, ⁵Boston Medical Center, Boston
Background/Purpose: MRI Osteoarthritis Knee Score (MOAKS) is a semi-quantitative scoring system used to assess MRI-detected structural abnormalities including over 100 raw scores representing multiple joint…
Abstract Number: 1163 • 2019 ACR/ARP Annual Meeting
Erosions Are the Most Often Reported Structural Lesion on MRI of the Sacroiliac Joints in axSpA Patients with IBP
Manouk de Hooge¹, Ann-Sophie De Craemer ¹, Thomas Renson ¹, Philippe Carron ¹, Liselotte Deroo ¹, Dirk Elewaut ¹ and Filip Van den Bosch ¹, ¹Ghent University Hospital, Ghent, Belgium
Background/Purpose: HLA-B27 and sacroiliitis on MRI form the basis of the Assessment of SpondyloArthritis international Society (ASAS) axial spondyloarthritis (axSpA) classification criteria. In addition, while…
Abstract Number: 2190 • 2019 ACR/ARP Annual Meeting
Multi-vendor Multi-site T1ρ and T2 Quantification of Knee Cartilage
Jeehun Kim ¹, Kenji Mamoto ², Richard Lartey ¹, Kaipin Xu ¹, Matthew Tanaka ³, Emma Bahroos ³, Carl Winalski ², Thomas Link ³, Peter Hardy ⁴, Qi Peng ⁵, Angie Botto-van Bemden ⁶, Kecheng Liu ⁷, Robert Peters ⁸, Can Wu ⁹ and Xiaojuan Li¹⁰, ¹Program of Advanced Musculoskeletal Imaging, Cleveland Clinic Foundation, Cleveland, ²Cleveland Clinic Foundation, Cleveland, ³University of California, San Francisco, San Francisco, ⁴University of Kentucky, Lexington, ⁵Albert Einstein College of Medicine, New York City, ⁶Arthritis Foundation, Atlanta, ⁷Siemens Medical Solution Inc, Malvern, ⁸GE Healthcare, Milwaukee, ⁹Philips Healthcare, Andover, ¹⁰Program of Advanced Musculoskeletal Imaging, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Osteoarthritis (OA) is a degenerative joint disease characterized by deterioration of articular cartilage in the joints. MRI T1ρ and T2 relaxation times have been…
Abstract Number: 1164 • 2019 ACR/ARP Annual Meeting
Novel Computer Assisted Methodology for Quantitative Assessment of MRI Treatment Responses to Apremilast in Patients with Psoriatic Arthritis
Paul Bird ¹, Mikael Boesen ², Mark Hinton ³, Eser Sanverdi ³, Romiesa Hagoug ³, Chrisotpher Sabin ³, Priscila Nakasato ⁴, Benoit Guerette ⁴ and Olga Kubassova⁵, ¹Optimus Research, Kogarah, New South Wales, Australia, ²Dept. of Radiology, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, ³Image Analysis Ltd, London, United Kingdom, ⁴Celgene Corporation, Summit, ⁵Image Analysis Group, London, United Kingdom
Background/Purpose: Response to treatment in Psoriatic Arthritis (PsA) can be captured using the OMERACT PsA Magnetic Resonance Imaging Score (PsAMRIS). While reliable and valid, PsAMRIS…
Abstract Number: 2196 • 2019 ACR/ARP Annual Meeting
Machine Learning Defines the Relationship Between Structural Knee Osteoarthritis and Patient-Important Outcomes: An 8-year Study of 47,858 Knee MRIs from the Osteoarthritis Initiative (OAI)
Michael Bowes¹, Katherine Kacena ², Oras Alabas ³, Alan Brett ¹, Bright Dube ⁴, Neil Bodick ⁵ and Philip G Conaghan ⁶, ¹Imorphics, Manchester, England, United Kingdom, ²BioBridges, Wellesley Hills, ³Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ⁴University of Leeds, LEEDS, England, United Kingdom, ⁵Flexion Therapeutics, Burlington, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom
Background/Purpose: Osteoarthritis (OA) is a slowly progressing disease which may be asymptomatic for many years. Therapy development has been hampered by poor understanding of both…
Abstract Number: 1171 • 2019 ACR/ARP Annual Meeting
Evidence of Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Minimal Disease Activity – Interim Analysis
Victoria Furer¹, Ari Polachek ², Liran Mendel ¹, David Levartovsky ³, Jonathan Wollman ⁴, Valerie Aloush ⁵, Ilana Kaufman ⁶, Hagit Sarbagil-Maman ⁷, Sara Borok ⁶, Mark Berman ⁶, Adi Broyde ⁶, Yael Lahat ¹, Mirna Zureik ¹, Sharon Nevo ¹, Daphna Paran ⁶, Iris Eshed ⁸ and Ori Elkayam ⁶, ¹Sourasky Medical Center, Tel-Aviv, Israel, ²Tel-Aviv Sourasky medical center, Tel Aviv, Israel, ³Sourasky medical center, Tel Aviv, Israel, ⁴Sourasky Medical Center, Herzelia, Israel, ⁵Tel Aviv Sourasky medical center, Tel Aviv, ⁶Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁷Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, ⁸Sheba Medical Center, Tel Aviv, Israel
Background/Purpose: Subclinical inflammatory lesions detected by MRI are prevalent in hand joints of patients with cutaneous psoriasis (1). Yet, it is unknown whether these inflammatory…
Abstract Number: 2213 • 2019 ACR/ARP Annual Meeting
Evaluation of Factors Associated with Bone Structure in an SLE Cohort Measured by Clinical 3T MRI and DEXA
Amit Saxena¹, Peter Izmirly ², Jill Buyon ², Stephen Honig ², Xiaoliu Zhang ³, Punam Saha ⁴, H. Michael Belmont ⁵ and Gregory Chang ², ¹New York University School of Medicine, New York, NY, ²NYU School of Medicine, New York, ³University of Iowa, Iowa City, ⁴University of Iowa Healthcare, Iowa City, ⁵New York University School of Medicine, Ney York
Background/Purpose: Osteoporosis and bone fractures are a frequent cause of morbidity in systemic lupus erythematosus (SLE), and are felt to be related both to disease…
Abstract Number: 1173 • 2019 ACR/ARP Annual Meeting
Magnetic Resonance Imaging in Patients in Clinical Remission: Tenosynovitis and Osteitis Are Independent Predictors of Radiographic and MRI Damage Progression
Signe Møller-Bisgaard¹, Kim Hørslev-Petersen ², Bo Ejbjerg ³, Merete Lund Hetland ⁴, Lykke Midtbøll Ørnbjerg ¹, Daniel Glinatsi ¹, Jakob Møller ⁵, Mikael Boesen ⁶, Kristian Stengaard-Pedersen ⁷, Ole Rintek Madsen ⁸, Bente Jensen ⁹, Jan Alexander Villadsen ¹⁰, Ellen-Margrethe Hauge ⁷, Philip Bennett ¹¹, Oliver Hendricks ¹², Karsten Asmussen ⁹, Marcin Kowalski ¹³, Hanne Lindegaard ¹⁴, Henning Bliddal ¹⁵, Niels Steen Krogh ¹⁶, Torkell Ellingsen ¹⁷, Agnete Nielsen ¹⁸, Lone Balding ⁵, Anne Grethe Jurik ¹⁹, Henrik Thomsen ⁵ and Mikkel Østergaard ²⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, ²Department of Rheumatology, King Christian X’s Hospital for Rheumatic Diseases Graasten, Denmark, Graasten, Denmark, ³Department of Rheumatology, Zealand University Hospital, Køge, Denmark, Køge, Denmark, ⁴DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ⁵Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark, ⁶Department of Radiology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, ⁷Department of Rheumatology, Department of Clinical Medicine, Aarhus University Hospital, Aarhus University, Aarhus, Denmark, Aarhus, Denmark, ⁸Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ⁹Department of Rheumatology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, ¹⁰Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, ¹¹Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte, Hellerup, Denmark, Copenhagen, Denmark, ¹²Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, Sønderborg, Denmark, ¹³Department of Rheumatology, Hjørring Hospital, Hjørring, Denmark, Hjørring, Denmark, ¹⁴Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, ¹⁵The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, ¹⁶Zitelab / DANBIO, Copenhagen, Denmark, ¹⁷Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark, ¹⁸Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, ¹⁹Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, ²⁰Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Progression of structural joint damage develops in 20-30 % of patients with rheumatoid arthritis (RA) in clinical remission1. Known predictors of structural damage progression…
Abstract Number: 2335 • 2019 ACR/ARP Annual Meeting
Prediction of Myocardial Fibrosis in Rheumatoid Arthritis Assessed by Cardiac Magnetic Resonance Imaging Using Artificial Neural Networks Models
Hitomi Kobayashi¹, Isamu Yokoe ², Yasuyuki Kobayashi ³, Eichi Takaya ⁴, Atsuma Nishiwaki ¹, Kaita Sugiyama ¹, Noboru Kitamura ¹, Masaki Haraoka ³ and Masami Takei ¹, ¹Nihon University School of Medicine, Tokyo, Japan, ²Kyoundo Hospital, Tokyo, Japan, ³St.Marianna University School of Medicine, Kawasaki, Japan, ⁴Graduate School, Keio University, Tokyo, Japan
Background/Purpose: Cardiac involvements cause of morbidity and mortality globally in rheumatoid arthritis (RA). Myocardial dysfunction may arise from a number of distinct processes, including myocardial…
Abstract Number: 1175 • 2019 ACR/ARP Annual Meeting
Periarticular Inflammation and Bone Marrow Oedema Are Important in the Evaluation of Enthesitis on MRI in Patients with Peripheral and Axial SpA
Xenofon Baraliakos¹, Philipp Sewerin ², Eugenio de Miguel ³, Christine Kleinmond ⁴, Ankita Shekhawat ⁵, Annette Wiedon ⁶ and Frank Behrens ⁷, ¹Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, ²Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, ³Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁴ClinProject GmbH, Eurasburg, Germany, ⁵Novartis Healthcare Pvt. Ltd., Hyderabad, India, ⁶Novartis Pharma GmbH, Nürnberg, Germany, ⁷CIRI/Rheumatology and Fraunhofer TMP, Goethe-University, Frankfurt, Germany
Background/Purpose: Enthesitis is a hallmark feature of Spondyloarthritis (SpA), and frequently localizes at the Achilles tendon1. Enthesitis is predominantly measured with clinical scores like Leeds…
Abstract Number: 2728 • 2019 ACR/ARP Annual Meeting
Efficacy and Safety of Upadacitinib in a Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 2/3 Clinical Study of Patients with Active Ankylosing Spondylitis
Désirée van der Heijde¹, In-Ho Song ², Aileen Pangan ³, Atul Deodhar ⁴, Filip Van den Bosch ⁵, Walter P. Maksymowych ⁶, Tae-Hwan Kim ⁷, Mitsumasa Kishimoto ⁸, Andrea Everding ⁹, Yunxia Sui ¹⁰, Xin Wang ¹⁰, Alvina D. Chu ¹⁰ and Joachim Sieper ¹¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, ³AbbVie Inc., North Chicago, ⁴Oregon Health & Science University, Portland, OR, ⁵Ghent University Hospital, Ghent, Belgium, ⁶University of Alberta/CARE ARTHRITIS, Edmonton, AB, Canada, ⁷Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ⁸Immuno-Rheumatology Center, St. Luke’s International Hospital, Tokyo, Japan, ⁹HRF Hamburger Rheuma Forschungszentrum, Hamburg, Germany, ¹⁰AbbVie Inc., Chicago, ¹¹Charité Universitätsmedizin Berlin, Germany, Berlin, Germany
Background/Purpose: Patients (pts) with ankylosing spondylitis (AS) who have an inadequate response/contraindication to NSAIDs have limited treatment options other than biologics. The Janus kinase (JAK)…
Abstract Number: 1179 • 2019 ACR/ARP Annual Meeting
Resting-State Functional Connectivity of Pain Processing Brain Region Associated with Therapeutic Response to Biologics in Rheumatoid Arthritis and Spondyloarthritis
Nobuya Abe¹, Yuichiro Fujieda ¹, Kuniyuki Asou ¹, Kohei Karino ², Michihito Kono ³, Hisashi Narita ⁴, Masaru Kato ¹, Khin Tha ⁵, Kenji Oku ¹, Olga Amengual ¹, Shinsuke Yasuda ¹ and Tatsuya Atsumi ⁶, ¹Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ³Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, ⁴Department of Psychiatry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁵Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, ⁶Hokkaido University, Sapporo, Japan
Background/Purpose: Background/Purpose: Discriminating inflammatory pain from non-inflammatory pain is critical to determine therapeutic strategy in inflammatory arthritis (IA) such as rheumatoid arthritis (RA) and spondyloarthritis…
Abstract Number: 2799 • 2019 ACR/ARP Annual Meeting
Does Early Anterior Cruciate Ligament Reconstruction Prevent Further Meniscal Damage? Secondary Analysis of a Randomized Controlled Trial
Barbara Snoeker ¹, Frank Roemer ², Aleksandra Turkiewicz ¹, Stefan Lohmander ³, Richard Frobell ¹ and Martin Englund¹, ¹Lund University, Lund, Sweden, ²University of Erlangen-Nuremberg, Erlangen, Germany, ³Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden, Lund, Sweden
Background/Purpose: It has been suggested that recurrent instability episodes in a non-reconstructed anterior cruciate ligament (ACL) injured knee increase the risk for an incident meniscal…

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