Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1L • 2017 ACR/ARHP Annual Meeting
Efficacy and Safety of Intra-Articular Sprifermin in Symptomatic Radiographic Knee Osteoarthritis: Results of the 2-Year Primary Analysis from a 5-Year Randomised, Placebo-Controlled, Phase II Study
Marc C. Hochberg¹, Ali Guermazi², Hans Guehring³, Aida Aydemir⁴, Stephen Wax⁵, Patricia Fleuranceau-Morel⁴, Asger Reinstrup Bihlet⁶, Inger Byrjalsen⁶, Jeppe Ragnar Andersen⁶ and Felix Eckstein⁷, ¹University of Maryland School of Medicine, Baltimore, MD, ²Boston Imaging Core Lab, LLC, and Boston University School of Medicine, Boston, MA, ³Merck KGaA, Darmstadt, Germany, ⁴EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, ⁵EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), BIllerica, MA, ⁶Nordic Bioscience, Herlev, Denmark, ⁷Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria

Background/Purpose: Sprifermin, a novel recombinant human fibroblast growth factor-18 is currently investigated as a potential disease-modifying osteoarthritis (OA) drug. Two-year primary data from a 5-year…
Abstract Number: 236 • 2017 ACR/ARHP Annual Meeting
Are Magnetic Resonance Imaging Features of the Hand Associated with Patient Reported Physical Function, Global Assessment of Disease Activity, Pain and Health Related Quality of Life in Rheumatoid Arthritis in Clinical Remission? – Longitudinal Results from an Observational Cohort
Daniel Glinatsi¹, Cecilie Heegaard Brahe², Merete Lund Hetland^1,3,4, Lykke Ørnbjerg¹, Simon Krabbe⁵, Joshua Baker⁶, Mikael Boesen⁷, Zoreh Rastiemadabadi⁸, Lone Morsel-Carlsen^8,9, Henrik Rogind^1,3, Hanne Slott Jensen¹⁰, Annette Hansen¹¹, Jesper Nørregaard¹², Søren Jacobsen^3,13, Lene Terslev¹, Tuan Huynh¹², Natalia Manilo¹⁴, Dorte Vendelbo Jensen^1,15, Jakob M. Møller¹⁶, Niels Steen Krogh¹⁵ and Mikkel Østergaard^1,3,17, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Glostrup, Denmark, ³University of Copenhagen, Copenhagen, Denmark, ⁴The DANBIO Registry, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ⁵Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, ⁶Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, ⁷Department of Radiology and the Parker institute, Copenhagen University Hospital Frederiksberg, Copenhagen, Denmark, ⁸Department of Radiology, Copenhagen University Hospital Frederiksberg, Copenhagen, Denmark, ⁹Department of Radiology, Rigshospitalet, Copenhagen, Denmark, ¹⁰Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Frederiksberg, Denmark, Copenhagen, Denmark, ¹¹Department of Rheumatology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark, ¹²Center for Rheumatology and Spine Diseases, Nordsjællands Hospital, Hillerød, Denmark, ¹³Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ¹⁴Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Frederiksberg, Copenhagen, Denmark, ¹⁵The DANBIO Registry, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ¹⁶Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, ¹⁷Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: To assess whether magnetic resonance imaging (MRI) inflammation and damage in the wrist and hand of rheumatoid arthritis (RA) patients are associated with patient-reported…
Abstract Number: 783 • 2017 ACR/ARHP Annual Meeting
European League Against Rheumatisms Recommendations for the Use of Imaging in Large Vessel Vasculitis in Clinical Practice
Christian Dejaco¹, Sofia Ramiro², Christina Duftner³, Florent L. Besson⁴, Thorsten Bley⁵, Daniel Blockmans⁶, Elisabeth Brouwer⁷, Marco A. Cimmino⁸, Eric Clark⁹, Bhaskar Dasgupta¹⁰, Andreas P Diamantopoulos¹¹, Haner Direskeneli¹², Annamaria Iagnocco¹³, Thorsten Klink⁵, Lorna Neill¹⁴, Cristina Ponte¹⁵, Carlo Salvarani¹⁶, Riemer Slart¹⁷, Madeline Whitlock¹⁸ and Wolfgang A. Schmidt¹⁹, ¹Rheumatology, Hospital of Bruneck, Bruneck, Italy, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³Department of Internal Medicine, Clinical Division of Internal Medicine II, Medical University Innsbruck, Innsbruck, Austria, ⁴Department of Nuclear Medicine, CHU Bicêtre, AP-HP, Université Paris-Sud, Paris, France, ⁵University of Würzburg, Würzburg, Germany, ⁶General Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium, ⁷Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁸Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy, ⁹PMRGCAuk, London, United Kingdom, ¹⁰Rheumatology, Southend University Hospital NHS Foundation Trust, Southend, UK, Westcliff-on-Sea, United Kingdom, ¹¹Rheumatology, Martina Hansens Hospital, Bærum, Oslo, Norway, ¹²Departement of İnternal Medicine, Division of Rheumatology, Marmara University, Istanbul, Turkey, ¹³Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy, ¹⁴PMRGCAuk, Dundee, United Kingdom, ¹⁵Instituto de Medicina Molecular (IMM), Rheumatology Research Unit, Lisbon, Portugal, ¹⁶Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy, ¹⁷University of Groningen, Enschede, Netherlands, ¹⁸Southend University Hospital, Southend, United Kingdom, ¹⁹Medical Center for Rheumatology and Clinical Immunology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany
Background/Purpose: Modern imaging modalities including ultrasound, magnetic resonance imaging (MRI), computed tomography (CT) and 18F-FDG positron emission tomography (PET/CT) have been increasingly used in primary…
Abstract Number: 1207 • 2017 ACR/ARHP Annual Meeting
Clinical Relevance of Structural Measures in Knee Osteoarthritis: Baseline Values and Change from Baseline Discriminate Patients Subsequently Receiving Knee Replacement
C. Kent Kwoh¹, Hans Guehring², Michael J Hannon³ and Aida Aydemir⁴, ¹University of Arizona Arthritis Center, Tuscan, AZ, ²Merck KGaA, Darmstadt, Germany, ³Medicine, University of Pittsburgh, Pittsburgh, PA, ⁴EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA
Background/Purpose: Structural measures of knee OA (KOA) progression include assessment of radiographic joint space width (JSW) and quantitative MRI (qMRI) measurement of cartilage thickness, both…
Abstract Number: 1875 • 2017 ACR/ARHP Annual Meeting
Assessment of Structural Damage of the Thumb Base in Patients with Hand Osteoarthritis: Comparing the Newly Developed Omeract Magnetic Resonance Imaging Scoring System with Standard Radiography
S. van Beest¹, F.P.B. Kroon¹, W. Damman¹, R. Liu¹, H.M. Kroon² and M. Kloppenburg³, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Thumb base osteoarthritis (OA) is characterized by structural damage, most commonly evaluated by radiography. However radiography is insensitive. Magnetic resonance (MR) imaging could be…
Abstract Number: 2300 • 2017 ACR/ARHP Annual Meeting
Predictive Value of Magnetic Resonance Imaging in Patients with Juvenile Idiopathic Arthritis in Clinical Remission
Clara Malattia¹, Marta Mazzoni Sr.², Stefania Viola Sr.², Angela Pistorio³, Francesca Magnaguagno⁴, Alessia Urro Jr.², Angelo Ravelli⁵ and Alberto Martini⁶, ¹Pediatria2 Reumatologia, Istituto Giannina Gaslini, Genoa, Italy, ²Pediatria 2 Reumatologia, Istituto Giannina Gaslini, Genova, Italy, ³Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy, ⁴UO Radiologia, Istituto Giannina Gaslini, Genoa, Italy, ⁵University of Genova, IRCCS Istituto Giannina Gaslini, Genova, Italy, ⁶Istituto Giannina Gaslini, Genoa, Italy
Background/Purpose: MRI studies on RA revealed that subclinical synovitis is common in patients in clinical remission and it is responsible for structural damage progression. MRI-detected…
Abstract Number: 2962 • 2017 ACR/ARHP Annual Meeting
MRI Results Following Discontinuation of Methotrexate in Patients with Rheumatoid Arthritis Treated with Subcutaneous Tocilizumab: Results from a Randomized Controlled Trial
Charles Peterfy¹, Joel Kremer², William F C Rigby³, Nora Singer⁴, Christine Birchwood⁵, Darcy Gill⁵, William Reiss⁵, Jinglan Pei⁵ and Margaret Michalska⁵, ¹Spire Sciences, Inc., Boca Raton, FL, ²Albany Medical College, Albany, NY, ³Geisel School of Medicine at Dartmouth, Lebanon, NH, ⁴Case Western Reserve University School of Medicine, Cleveland, OH, ⁵Genentech, Inc., South San Francisco, CA
Background/Purpose: Although previous studies have established the efficacy of tocilizumab (TCZ) initiated as monotherapy (MONO) for the treatment of rheumatoid arthritis (RA),1,2 changes in active…
Abstract Number: 18L • 2016 ACR/ARHP Annual Meeting
Primary CNS Vaculitis Vs Neurosarcoidosis: Can We Predict the Diagnosis with MRI?
Didem Saygin¹, Priya Sundaram-Simonelli², Leonard H. Calabrese³, Elisabeth Ray⁴, William Messner⁵, Stephen Jones², Jinny Tavee⁶ and Rula A Hajj-Ali⁷, ¹Cleveland Clinic, Cleveland, OH, ²Neuroradiology, Cleveland Clinic, Cleveland, OH, ³Rheumatic & Immunologic Disease, Cleveland Clinic, Cleveland, OH, ⁴Rheumatology, Cleveland Clinic, Cleveland, OH, ⁵Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, ⁶Neuromuscular diseases, Cleveland Clinic, Cleveland, OH, ⁷Rheumatic and Immunologic Dis, Cleveland Clinic, Cleveland, OH

Background/Purpose: Neurosarcoidosis and primary angiitis of central nervous system (PACNS) are inflammatory diseases affecting central nervous system, with overlapping clinical and pathological characteristics. Differentiating between…
Abstract Number: 1297 • 2016 ACR/ARHP Annual Meeting
Positive Sacroiliac Joint MRI in Asymptomatic Patients with Recurrent Acute Anterior Uveitis: A Proof of Concept
Thauana Oliveira¹, Walter Maksymowych², Robert G Lambert³, Cristina Muccioli¹ and Marcelo Pinheiro¹, ¹Federal University of São Paulo, São Paulo, Brazil, ²Medicine, University of Alberta,, Edmonton, AB, Canada, ³Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Recurrent acute anterior uveitis (rAAU) is associated with spondyloarthritis (SpA). However, it is not known if patients with rAAU, but no back symptoms could…
Abstract Number: 1306 • 2016 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging Measures of Disease Activity in Rheumatoid Arthritis Patients Treated with Multiple Regimens of DMARD Therapy
Paolo Pace¹, Arthur Lau², Jonathan D. Adachi³, Matthew A. Jessome⁴, George Ioannidis² and Minta Patel⁵, ¹Rheumatology, McMaster Unversity, Hamilton, ON, Canada, ²St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, ⁵Cambridge Memorial Hospital, Cambridge, ON, Canada
Background/Purpose: Magnetic resonance imaging ( MRI ) in rheumatoid arthritis ( RA ) has been shown to be more sensitive than clinical and radiological parameters…
Abstract Number: 1781 • 2016 ACR/ARHP Annual Meeting
Analysis of Influences of Various Factors on the Prognosis of Acute Confusional State of Diffuse Psychiatric/Neuropsychological Syndromes in Systemic Lupus Erythematosus
Gakuro Abe¹, Yoshiyuki Arinuma¹, Hirotoshi Kikuchi² and Shunsei Hirohata¹, ¹Kitasato University School of Medicine, Sagamihara, Japan, ²Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
Background/Purpose: Neuropsychiatric systemic lupus erythematosus (NPSLE), especially diffuse psychiatric/neuropsychological syndromes (diffuse NPSLE), is one of the most difficult complications of the disease. For the evaluation…
Abstract Number: 2317 • 2016 ACR/ARHP Annual Meeting
Preliminary Validation of a Magnetic Resonance Imaging-Based Inflammatory Scoring System in Adult Myositis
Nicolo Pipitone¹, Antonella Notarnicola^2,3, Arnaldo Scardapane⁴, Lucia Spaggiari⁵, Gabriele Levrini⁶, Florenzo Iannone⁷, Carlo Salvarani⁸, Giovanni Lapadula⁹, Ingrid E. Lundberg², Pierpaolo Pattacini¹⁰ and Giulio Zuccoli¹¹, ¹Rheumatology, Arcispedale S. M. Nuova, Reggio Emilia, Italy, ²Department of Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ³Rheumatology, Bari University, Bari, Italy, ⁴Radiology, University of Bari, Bari, Italy, ⁵Radiology, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁶Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁷Bari University, Rheumatology, Bari, Italy, ⁸Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, ⁹Rheumatology Unit, University of Bari, Bari, Italy, ¹⁰Radiology, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy, ¹¹Children's Hospital of Pittsburgh, Pittsburgh, PA
Background/Purpose: in patients with active myositis, magnetic resonance imaging (MRI) often demonstrates muscle edema thought to represent active inflammation. An MRI-based muscle inflammatory scoring system…
Abstract Number: 2367 • 2016 ACR/ARHP Annual Meeting
Association Between MRI-Detected Osteophytes and Changes in Knee Pain and Structures in Older Adults: A Population Based Cohort Study
Zhaohua Zhu¹, Laura Laslett², Xingzhong Jin³, Weiyu Han¹, Benny Samuel Eathakkattu Antony⁴, Xia Wang⁵, Flavia M Cicuttini⁶, Graeme Jones^7,8 and Changhai Ding⁷, ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ³Menzies institute for Medical Research, University of Tasmania, Hobart, Australia, ⁴Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ⁵Menzies institute for medical research, University of Tasmania, Hobart, Australia, ⁶Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia, ⁷Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁸Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose: Osteophyte (OP) formation is one of the clinical features of osteoarthritis (OA), so early detection of OP formation can be of diagnostic value. OP…
Abstract Number: 3090 • 2016 ACR/ARHP Annual Meeting
Inflammation Detected with Modern Sensitive MRI Analysis Demonstrates That Therapeutic Response As Early As One Month Predicts 12-Month Radiographic Progression: Data from a Study Using Tofacitinib and Methotrexate in Early RA
Philip G. Conaghan¹, Michael A Bowes², Mikkel Østergaard³, Gwenael Guillard², Douglass Chapman⁴, Amy Stein⁵, John Andrews⁴, Zhiyong Xie⁶, Andrew Koenig⁷, Koshika Soma⁴ and Bethanie Wilkinson⁶, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Pfizer Inc, New York, NY, ⁵Biostatistics, Quintiles, Morrisville, NC, ⁶Pfizer Inc, Groton, CT, ⁷Pfizer Inc, Collegeville, PA
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. A novel automated quantification method for RA MRI-detected pathology using statistical shape…
Abstract Number: 3158 • 2016 ACR/ARHP Annual Meeting
What Predicts Absence of Spinal Damage in Patients with Spondyloarthritis after Prolonged Follow up?
Walter Maksymowych¹, Stephanie Wichuk¹, Praveena Chiowchanwisawakit², Robert G Lambert³ and Susanne J Pedersen⁴, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Medicine, Mahidol University, Bangkok, Thailand, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Rheumatology, Copenhagen University Hospitals, Copenhagen, Denmark
Background/Purpose: After 20 years of follow up the majority of patients with aspondyloarthritis (SpA) have developed new bone in the spine although disease may remain…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].