Abstracts tagged "large vessel vasculitis"

Abstract Number: 2920 • 2019 ACR/ARP Annual Meeting
Comparison of Arterial Patterns of Disease in Takayasu’s Arteritis and Giant Cell Arteritis
K Bates Gribbons¹, Cristina Ponte ², Anthea Craven ³, David Cuthbertson ⁴, Simon Carette ⁵, Gary S. Hoffman ⁶, Nader A. Khalidi ⁷, Curry L. Koening ⁸, Carol Langford ⁹, Kathleen Maksimowicz-McKinnon ¹⁰, Carol A. McAlear ¹¹, Paul Monach ¹², Larry Moreland ¹³, Christian Pagnoux ¹⁴, Kaitlin Quinn ¹⁵, Joanna Robson ¹⁶, Philip Seo ¹⁷, Antoine Sreih ¹⁸, Ravi Suppiah ¹⁹, Kenneth Warrington ²⁰, Steven Ytterberg ²¹, Raashid Luqmani ³, Richard Watts ²², Peter Merkel ¹⁸ and Peter C. Grayson ²³, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ³University of Oxford, Oxford, United Kingdom, ⁴University of South Florida, Tampa, FL, ⁵Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, Canada, ⁶Cleveland Clinic Foundation, Cleveland, OH, ⁷McMaster University, Hamilton, ON, Canada, ⁸University of Utah Hospital, Salt Lake City, UT, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Henry Ford Hospital, Wayne State University, Detroit, MI, ¹¹University of Pennsylvania - VCRC Project Manager, Philadelphia, PA, ¹²Brigham and Women's Hospital, Boston, MA, ¹³University of Pittsburgh, PITTSBURGH, PA, ¹⁴Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, ¹⁵Georgetown University Hospital/National Institutes of Health, Washington, DC, ¹⁶Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ¹⁷Johns Hopkins Medicine, Baltimore, MD, ¹⁸University of Pennsylvania, Philadelphia, PA, ¹⁹Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ²⁰Mayo Clinic Rochester, Rochester, MN, ²¹Mayo Clinic College of Medicine, Rochester, MN, ²²Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ²³National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Current classification criteria differentiate between Takayasu’s arteritis (TAK) and giant cell arteritis (GCA), the two most common forms of large-vessel vasculitis, based primarily on…
Abstract Number: 2922 • 2019 ACR/ARP Annual Meeting
Imaging Acquisition Technique Influences Interpretation of Positron Emission Tomography Vascular Activity in Large-Vessel Vasculitis
Kaitlin Quinn¹, Joel S. Rosenblum ², Casey A. Rimland ³, K Bates Gribbons ⁴, Mark A. Ahlman ⁵ and Peter C. Grayson ⁶, ¹Georgetown University Hospital/National Institutes of Health, Washington, DC, ²National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, ³National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, ⁴National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁵Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, ⁶National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) is one of several imaging modalities used in the assessment of patients with large-vessel vasculitis (LVV). Conventionally PET…
Abstract Number: 293 • 2019 ACR/ARP Annual Meeting
False Positives in the Ultrasound Diagnosis of Giant Cell Arteritis: Some Diseases Can Also Have Halo Sign
Elisa Fernández¹, Irene Monjo ², Gema Bonilla ³, Chamaida Plasencia ⁴, Maria-Eugenia Miranda-Carus ², Alejandro Balsa ⁴ and Eugenio de Miguel ⁵, ¹Rheumatology Department, La Paz University Hospital, Madrid, Madrid, Spain, ²FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, Spain, ³Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, Madrid, Spain, ⁴Immuno-Rheumatology Research Group, IdiPaz & Rheumatology Department. La Paz University Hospital, Madrid, Spain, ⁵Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain
Background/Purpose: Giant cell arteritis (GCA) is the most common systemic vasculitis in the elderly. The halo sign is an accepted valid test for the diagnosis…
Abstract Number: 372 • 2019 ACR/ARP Annual Meeting
Periaortitis and Coronary Arteritis in IgG4-Related Disease: Eastern Mediterranean Experience
Gozde Kubra Yardımcı ¹, Alper Sarı ¹, Abdulsamet Erden ², Ertugrul Cagri Bolek ¹, Bayram Farisoğulları ¹, Levent Kilic ³, Berkan Armagan ⁴, Umut Kalyoncu ⁵, Tuncay Hazırolan ⁶, Ali İhsan Ertenli ¹ and Omer Karadag⁷, ¹Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, ²Ministry of Health Ankara City Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ³Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ⁴Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Ankara, Turkey, ⁵Hacettepe University Department of Rheumatology, Ankara, Turkey, ⁶Hacettepe University, Division of Radiology, Ankara, ⁷Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey
Background/Purpose: Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that may involve multiple organ systems. IgG4-RD can also lead to large vessel vasculitis and…
Abstract Number: 819 • 2018 ACR/ARHP Annual Meeting
Use of Takayasu Arteritis Damage Score (TADS) to Measure Damage in Takayasu Arteritis
Sivakumar Mambakkam Rajappa¹ and Krishnamurthy Venkataraman², ¹Rheumatology and Immunology, GLB Hospitals, Chennai, India, ²Rheumatology, Apollo Speciality Hospitals, Chennai, India
Background/Purpose: Takayasu Arteritis (TA) in India frequently present with complications, indicating the need for a specific damage index to capture the accumulation of disease-related scars…
Abstract Number: 2196 • 2018 ACR/ARHP Annual Meeting
Kinetics of Tissue-Specific Distribution of 18f-Fluorodeoxyglucose in Positron Emission Tomography in Large Vessel Vasculitis
Joel S. Rosenblum¹, Kaitlin Quinn², Mark A. Ahlman³ and Peter C. Grayson⁴, ¹NIAMS, National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, ²Systemic Autoimmunity Branch, NIAMS, Bethesda, MD, ³Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁴National Institute of Arthritis, Musculoskeletal and Skin Disease, National Institutes of Health, Bethesda, MD
Background/Purpose: 18F-fluorodeoxyglucose (FDG) PET may be used to quantify vascular inflammation in large-vessel vasculitis (LVV). Quantitative analysis of arterial FDG uptake has not been standardized. Delayed…
Abstract Number: 2746 • 2018 ACR/ARHP Annual Meeting
Tocilizumab Monotherapy for Large Vessel Vasculitis: Results of 104-Week Treatment of a Prospective, Single-Center, Open Study
Shuntaro Saito, Ayumi Okuyama, Yusuke Okada, Akiko Shibata, Ryota Sakai, Kentaro Chino, Takahiko Kurasawa, Tsuneo Kondo, Hirofumi Takei and Koichi Amano, Department of Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University, Saitama, Japan
Background/Purpose: To evaluate the efficacy and safety of tocilizumab (TCZ) monotherapy for Large Vessel Vasculitis (LVV), including Takayasu arteritis (TAK) and Giant cell arteritis (GCA).…
Abstract Number: 2759 • 2018 ACR/ARHP Annual Meeting
Effect of Specific Treatments on Clinical, Serologic, and Imaging Assessments of Disease Activity in Large-Vessel Vasculitis
Shubhasree Banerjee¹, Kaitlin Quinn², Katherine B. Gribbons³, Joel S. Rosenblum⁴, Ali Civelek⁵, Elaine Novakovich⁶, Armin Bagheri¹, Peter A. Merkel⁷, Mark A. Ahlman⁸ and Peter C. Grayson⁹, ¹Systemic Autoimmunity Branch, NIAMS, NIH, Bethesda, MD, ²Systemic Autoimmunity Branch, NIAMS, Bethesda, MD, ³Systemic Autoimmunity Branch, National Institute of Arthritis and Skin and Musculoskeletal Disease, Bethesda, MD, ⁴NIAMS, National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, ⁵National Institutes of Health, Clinical Center, Radiology and Imaging Sciences, Bethesda, MD, ⁶National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁷University of Pennsylvania, Philadelphia, PA, ⁸Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁹National Institute of Arthritis, Musculoskeletal and Skin Disease, National Institutes of Health, Bethesda, MD
Background/Purpose: Disease activity in large vessel vasculitis (LVV) is traditionally assessed by clinical and serologic (ESR, CRP) parameters. Imaging assessment, including 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET),…
Abstract Number: 2778 • 2018 ACR/ARHP Annual Meeting
High Prevalence of Vascular Surgery and Autoimmune Comorbidity in Takayasu Arteritis
Tsuyoshi Shirai¹, Tomoyuki Muto², Yuko Shirota¹, Hiroshi Fujii¹, Tomonori Ishii³ and Hideo Harigae¹, ¹Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan, ²Tohoku University Graduate School of Medicine, Sendai, Japan, ³Clinical Research, Innovation and Education Center, Tohoku University Hospital, Sendai, Japan
Background/Purpose: Large vessel vasculitis (LVV) is the arteritis in aorta and its major branches, and classified into Takayasu arteritis (TAK) and giant cell arteritis (GCA).…
Abstract Number: 102 • 2017 ACR/ARHP Annual Meeting
Incorporating Temporal Artery Ultrasound in a UK District General Hospital with No Prior Colour Doppler Sonography Service: An Encouraging Preliminary Analysis
Othman Kirresh¹, Chintu Gademsetty² and Charles Li¹, ¹Rheumatology, NHS Royal Surrey County Hospital, Surrey, United Kingdom, ²Radiology, NHS Royal Surrey County Hospital, Surrey, United Kingdom
Background/Purpose: Temporal Arteritis (TA) is the most common large vessel vasculitis, affecting adults over the age of 50. It is associated with significant morbidity due…
Abstract Number: 785 • 2017 ACR/ARHP Annual Meeting
Longitudinal Angiographic Findings in Patients with Takayasu’s Arteritis
Antoine G. Sreih¹, Tanaz A. Kermani², David Cuthbertson³, Simon Carette⁴, Lindsy J. Forbess⁵, Nader A. Khalidi⁶, Curry L. Koening⁷, Carol A. McAlear⁸, Paul A. Monach⁹, Larry W. Moreland¹⁰, Christian Pagnoux¹¹, Philip Seo¹², Robert F. Spiera¹³, Kenneth J. Warrington¹⁴, Steven R. Ytterberg¹⁴, Carol A. Langford¹⁵ and Peter A. Merkel^16,17, ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Division of Rheumatology, University of California, Los Angeles, CA, ³Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, ⁴Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁵Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁶Rheumatology, McMaster University, Hamilton, ON, Canada, ⁷Rheumatology, University of Utah, Salt Lake City, UT, ⁸University of Pennsylvania, Philadelphia, PA, ⁹Boston University School of Medicine, Boston, MA, ¹⁰Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹¹Rheumatology-Vasculitis clinic, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹²Medicine, Johns Hopkins University, Baltimore, MD, ¹³Rheumatology, Hospital for Special Surgery, New York, NY, ¹⁴Rheumatology, Mayo Clinic, Rochester, MN, ¹⁵Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ¹⁶Biostatistics, Epidemiology, and Bioinformatics, University of Pennsylvania, Philadelphia, PA, ¹⁷Division of Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose : Longitudinal data on the type, progression, and predictors of arterial lesions in patients with Takayasu’s arteritis (TAK) is limited. This study aimed to…
Abstract Number: 788 • 2017 ACR/ARHP Annual Meeting
Mast Cell Mediated Inhibition of Systemic IL-6 in candida Albicans Water-Soluble Fraction (CAWS) Induced Model of Large Vessel Vasculitis
Mingcai Zhang¹, Mehrdad Maz², Don Smith³, Noriko Miura⁴, Naohito Ohno⁵, Kottarappat Dileepan⁶ and Jason Springer⁷, ¹Department of Orthopedics, University of Kansas Medical Center, Kansas City, KS, ²Allergy, Clinical Immunology, and Rheumatology, Division of Allergy, Clinical Immunology and Rheumatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, ³University of Kansas Medical Center, Kansas City, KS, ⁴School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan, ⁵Tokyo University of Pharmacy and Lift Sciences, Tokyo, Japan, ⁶Department of Medicine, University of Kansas Medical Center, Kansas, KS, ⁷Department of Internal Medicine, Division of Allergy, Clinical Immunology, & Rheumatology, Kansas University Medical Center, Kansas City, KS
Background/Purpose: In forms of large vessel vasculitis (LVV) systemic IL-6 has been shown to follow disease activity. Furthermore, IL-6 inhibition is an effective treatment for…
Abstract Number: 795 • 2017 ACR/ARHP Annual Meeting
Characteristics and Treatment Outcomes of Giant Cell Arteritis with Large-Vessel Lesions in a Nationwide, Retrospective Cohort Study in Japan
Takahiko Sugihara¹, Hitoshi Hasegawa², Haruhito Uchida³, Hajime Yoshifuji⁴, Yoshikazu Nakaoka⁵, Yoshiko Watanabe⁶, Eisuke Amiya⁷, Masanori Konishi⁸, Yasuhiro Katsumata⁹, Yoshinori Komagata¹⁰, Taio Naniwa^11,12, Takahiro Okazaki¹³, Yoshiya Tanaka¹⁴, Tsutomu Takeuchi¹⁵, Masayoshi Harigai¹⁶, Yoshihiro Arimura¹⁷ and Mitsuaki Isobe^8,18, ¹Department of Medicine and Rheumatology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan, ²Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Ehime, Japan, ³Department of Chronic Kidney Disease and Cardiovascular Disease, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, ⁴Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ⁵Osaka University Graduate School of Medicine, Osaka, Japan, ⁶First Department of Physiology, Kawasaki Medical School, Kurashiki, Japan, ⁷Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan, ⁸Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan, ⁹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ¹⁰First Dept. of Internal Medicine, Kyorin University School of Medicine, Tokyo, Japan, ¹¹Division of Rheumatology, Dept of Internal Medicine,, Nagoya City University Hospital, Nagoya, Japan, ¹²Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, ¹³Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ¹⁴The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan, ¹⁵Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ¹⁶Division of Epidemiology and Pharmacoepidemiology of Rheumatic Diseases, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ¹⁷First Department of Internal Medicine, Kyorin University School of Medicine, Tokyo, Japan, ¹⁸Sakakibara Heart Institute, Tokyo, Japan
Background/Purpose: Giant cell arteritis (GCA) often affects aorta or its branches, but it is unclear whether the large-vessel (LV) lesions are associated with treatment outcomes.…
Abstract Number: 801 • 2017 ACR/ARHP Annual Meeting
PET-CT Findings and Clinical Outcomes in Takayasu Arteritis – Does 18F-Fluorodeoxyglucose Uptake in Arteries Predict Relapses?
Anna Larissa Faria Janes¹, Míriam Fang Castro¹, Bruna Savioli¹, Anne Elisabeth Diniz Arraes¹, Emilia Sato² and Alexandre W.S. Souza³, ¹Internal Medicine - Rheumatology Division, Universidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, Brazil, ²Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ³Rheumatology Div/Dept of Med, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil
Background/Purpose: PET-CT scan with 18F-Fluorodeoxyglucose (18F-FDG) has been frequently used as a tool to assess disease activity in Takayasu arteritis (TA) and increased 18F-FDG uptake…
Abstract Number: 824 • 2017 ACR/ARHP Annual Meeting
Long Term Efficacy and Safety of Intravenous and Subcutaneous Biologics in Large Vessels Vasculitis: 21 Patients Belonging to a Single Italian Center from 2011 to 2017
Paola Toniati¹ and Angela Tincani², ¹RHEUMATOLOGY, SPEDALI CIVILI, BRESCIA, Italy, ²University and Spedali Civili of Brescia, Brescia, Italy
Background/Purpose: Large vessels vasculitis (LVV) is the most common form of primary vasculitis comprising giant cell arteritis (GCA) and Takayasu arteritis (TAK) and aortitis. Methods:…

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