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Abstracts tagged "large vessel vasculitis"

  • Abstract Number: 013 • 2020 Pediatric Rheumatology Symposium

    A Preliminary Data-driven Anatomic Classification for Childhood Takayasu Arteritis (cTA)

    Ellen Go1, Simon Eng 2, David Cabral 3 and Rae Yeung 1, 1The Hospital for Sick Children, Toronto, Canada, 2Toronto, Canada, 3BC Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada

    Background/Purpose: The pattern of arterial involvement and disease severity varies in those affected with cTA. Distinct imaging patterns that have some congruence with clinical phenotype…
  • Abstract Number: 106 • 2020 Pediatric Rheumatology Symposium

    Childhood-onset Takayasu Arteritis: A Single Center Case Series of Atypical and Varied Presentations

    Uptej Khalsa1 and Imelda Balboni 1, 1Stanford University, Palo Alto, California

    Background/Purpose: Childhood-onset Takayasu arteritis is a rare inflammatory vessel disease that predominantly affects the aorta and its major branches. Clinical presentation at disease onset can…
  • Abstract Number: 767 • 2019 ACR/ARP Annual Meeting

    Outcome Measures in Large-Vessel Vasculitis: Relationships Between Patient, Physician, Imaging, and Laboratory-Based Domains

    Casey A. Rimland1, Kaitlin Quinn 2, Joel S. Rosenblum 3, Mollie Schwartz 4, K Bates Gribbons 5, Elaine Novakovich 6, Antoine Sreih 7, Peter Merkel 7, Mark A. Ahlman 8 and Peter C. Grayson 9, 1National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, 2Georgetown University Hospital/National Institutes of Health, Washington, DC, 3National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, 4University of Maryland, Baltimore, MD, 5National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 6National Institutes of Health, Bethesda, MD, 7University of Pennsylvania, Philadelphia, PA, 8Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, 9National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD

    Background/Purpose: Large-vessel vasculitis (LVV) is characterized by inflammation of the aorta and its major branches. The most common forms of LVV include giant cell arteritis…
  • Abstract Number: 798 • 2019 ACR/ARP Annual Meeting

    Development of Large Vessel Vasculitis Including Aortitis in a Patient with Deficiency of the IL-1 Receptor Antagonist (DIRA) Points to Converging Roles of IL-1 and TNF in Vascular Pathogenesis Recapitulating Findings from a Murine Model

    Gina Montealegre Sanchez1, Adriana de Jesus 1, Jenna Wade 2, Katherine Townsend 1, Arianne Soldatos 3, Alessandra Brofferio 4, Peter C. Grayson 5, Ginger Janow 6 and Raphaela Goldbach-Mansky 1, 1Translational Autoinflammatory Disease Section/NIAID/NIH, Bethesda, 2Translational Autoinflammatory Diseases Section/NIAID/NIH, Bethesda, 3NIH/NINDS, Bethesda, 4NIH/NHLBI, Bethesda, 5National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD, 6Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, NJ

    Background/Purpose: Deficiency of interleukin-1-receptor antagonist (DIRA) is a rare autoinflammatory disease caused by autosomal recessive loss of function mutations in IL1RN and characterized by early-onset generalized pustulosis,…
  • Abstract Number: 1210 • 2019 ACR/ARP Annual Meeting

    Utilization of a Multispecialty Team for the Diagnosis of Giant Cell Arteritis Reduces Patient Morbidity

    Arash Hassantoufighi 1, Rachel Lu-Do1, Mamta Sherchan 1, Christopher Collins 1, Joshpaul Dhillon 2 and Florina Constantinescu 1, 1MedStar Washington Hospital Center, Department of Rheumatology, Washington, DC, 2MedStar Washington Hospital Center, Department of Internal Medicine, Washington, DC

    Background/Purpose: Giant Cell Arteritis (GCA) is an autoimmune vasculitis, most common in older adults with a peak incidence in the seventh decade. The diagnosis is…
  • Abstract Number: 1964 • 2019 ACR/ARP Annual Meeting

    A Role for Microbiota in the Pathophysiology of Takayasu Arteritis (TAK) and Giant Cell Arteritis (GCA)

    Anne Desbois1, Dragos Ciocan 2, David Saadoun 1, Gabriel Perlemuter 3 and Patrice Cacoub 4, 1GHPS, Paris, France, 2Hôpital Antoine Beclere, Clamart, France, 3Hôpital Clamart, Paris, France, 4AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Paris, France

    Background/Purpose: The pathogenesis of Large Vessel Vasculitis (LVV) is not well understood. There is increasing evidence of a close link between intestinal dysbiosis and systemic…
  • Abstract Number: 2644 • 2019 ACR/ARP Annual Meeting

    Ultrasound to Monitor Treatment Response in Large Vessel Giant Cell Arteritis

    Anne Bull Haaversen1, Viktoria Holt 2, Shagaye Nabizadeh 2, Annicken Slagsvold 2 and Andreas P Diamantopoulos 3, 1Martina Hansens Hospital, Sandvika, Norway, 2Martina Hansens Hospital, Bærum, Norway, 3Martina Hansens Hospital, SANDVIKA, Oslo, Norway

    Background/Purpose: On ultrasound (US) examinations, large vessel vasculitis (LVV) has been reported to be present in up to 55% of Giant cell arteritis (GCA) patients.…
  • Abstract Number: 2646 • 2019 ACR/ARP Annual Meeting

    Survival of Large Vessel Giant Cell Arteritis in Northern Italy During a 26-year Period : No Correlation with Demographical, Clinical, Laboratory and Imaging Data

    Luigi Boiardi1, Mariagrazia Catanoso 2, Giovanna Restuccia 3, Francesco Muratore 3, Pierluigi Macchioni 4 and Carlo Salvarani 5, 1Division of Rheumatology, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, 2Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, ITALY, Reggio Emilia, Italy, 3Division of Rheumatology, Azienda Unita’ Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, 4Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, 5Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy

    Background/Purpose: To investigate the relationship between demographical, clinical, laboratory and imaging data and survival in patients with large vessel giant cell arteritis (LVGCA) in a…
  • Abstract Number: 2664 • 2019 ACR/ARP Annual Meeting

    Color Doppler Ultrasound for the Diagnosis of Giant Cell Arteritis in Montreal: A Canadian Single Center Experience

    Jean-Paul Makhzoum1, Meriem Belhocine 1, Michelle Goulet 1, Maxime Rheaume 1, Tara Starnino 2, Stephanie Ducharme-Benard 2, Guillaume Febrer 3, Yves Troyanov 4, Nathalie Routhier 5, Rosalie-Selene Meunier 5, Isabelle Chagnon 5, Michel Laurier 5, Maggy Helou 5, Nathalie Morency 6 and Anne-Marie Mansour 1, 1Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, 2Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, 3Vascular Surgery, Department of Surgery, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, 4Division of Rheumatology, Department of Medicine, Hôpital du Sacre-Coeur de Montreal, Montreal, QC, Canada, 5Internal Medicine, Department of Medicine, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, 6Division of Rheumatology, Department of Medicine, Montreal, Canada

    Background/Purpose: Giant Cell Arteritis (GCA) remains challenging to diagnose as false negative temporal artery biopsy (TAB) can occur. Color doppler ultrasonography (CDUS) of the temporal,…
  • Abstract Number: 2673 • 2019 ACR/ARP Annual Meeting

    Presentation and Management of Giant Cell Arteritis in a Real-World Setting (Artemis Study)

    Alfred Mahr1, Eric Hachulla 2, Hubert de BOYSSON 3, Nassim Guerroui 4, Emmanuel Héron 5, Stéphane Vinzio 6, Jonathan Broner 7, François-Xavier Lapebie 8, Martin Michaud 9, Laurent Sailler 8, Thierry Zenone 10, Mohamed Djerad 11, Mathieu Jouvray 12, Emilie Shipley 13, Nathalie Tieulie 14, Isabelle Idier 15, Marc Paccalin 16 and Valérie Devauchelle Pensec 17, 1Hospital Saint-Louis, University Paris Diderot, Paris, France, 2Dept. of Internal Medicine and Clinical Immunology, Hôpital Claude Huriez, University of Lille, Lille, France, Lille, France, 3University Hospital of Caen, Caen, France, 4European Hospital of Marseille, Marseille, France, 5Quinze-Vingt Hospital, Paris, France, 6GHM Grenoble, Grenoble, France, 7University Hospital of Nîmes, Nîmes, France, 8University Hospital of Toulouse, Toulouse, France, 9Joseph Ducuing Hospital, Toulouse, France, 10Hospital of Valence, Valence, France, 11Hospital of Nevers, Nevers, France, 12Hospital of Arras, Arras, France, 13Hospital of Dax, Dax, France, 14University Hospital of Nice, Nice, France, 15Chugai Pharma France, Paris La Défense, France, 16University Hospital of Poitiers, Poitiers, France, 17University Hospital of Brest, Brest, France

    Background/Purpose: We have few real-world data on the natural history and care of patients with giant cell arteritis (GCA). The objective of this observational study…
  • Abstract Number: 2690 • 2019 ACR/ARP Annual Meeting

    Fast Track Clinic (FTC) for Giant Cell Arteritis (GCA) – the United States Experience

    Ingeborg Sacksen 1, Elizabeth Jernberg 1, Scott Pollock 2, Jean Liew 3, Sarah Chung 2, R Eugene Zierler 3 and Alison Bays2, 1University of Washington Division of Rheumatology, Seattle, 2University of Washington Division of Rheumatology, Seattle, WA, 3University of Washington, Seattle, WA

    Background/Purpose: Giant cell arteritis (GCA) is the most common form of vasculitis in adults and if untreated, may  result in visual impairment. Although the gold…
  • Abstract Number: 2692 • 2019 ACR/ARP Annual Meeting

    Coronary Artery Disease in a Population-Based Cohort of Biopsy-Proven Giant Cell Arteritis in Southern Sweden

    Pavlos Stamatis1, Moman Mohammad 1, Peter Merkel 2, Martin Englund 3, Carl Turesson 4, David Erlinge 1 and Aladdin Mohammad 1, 1Lund University, Lund, Skane Lan, Sweden, 2University of Pennsylvania, Philadelphia, PA, 3Lund University, Lund, Sweden, 4Lund University, Malmö, Sweden

    Background/Purpose: The aim of this study was to estimate the incidence rate and prevalence of coronary artery diseases (CAD) in patients with temporal artery positive…
  • Abstract Number: 2919 • 2019 ACR/ARP Annual Meeting

    Endothelial Protein C Receptor and Scavenger Receptor Class B Type 1 Negatively Regulate Vascular Inflammation and Are Major Autoantigens in Takayasu Arteritis

    Tomoyuki Mutoh1, Tsuyoshi Shirai 1, Tomonori Ishii 2, Yuko Shirota 3, Hideo Harigae 1 and Hiroshi Fujii 1, 1Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan, 2Tohoku University Hospital, Sendai, Japan, 3Department of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University, Sendai, Japan

    Background/Purpose: Takayasu arteritis (TAK) is a chronic vasculitis which predominantly affects large vessels. Although anti-endothelial cell antibodies (AECA) had been reported to be involved in…
  • Abstract Number: 2920 • 2019 ACR/ARP Annual Meeting

    Comparison of Arterial Patterns of Disease in Takayasu’s Arteritis and Giant Cell Arteritis

    K Bates Gribbons1, Cristina Ponte 2, Anthea Craven 3, David Cuthbertson 4, Simon Carette 5, Gary S. Hoffman 6, Nader A. Khalidi 7, Curry L. Koening 8, Carol Langford 9, Kathleen Maksimowicz-McKinnon 10, Carol A. McAlear 11, Paul Monach 12, Larry Moreland 13, Christian Pagnoux 14, Kaitlin Quinn 15, Joanna Robson 16, Philip Seo 17, Antoine Sreih 18, Ravi Suppiah 19, Kenneth Warrington 20, Steven Ytterberg 21, Raashid Luqmani 3, Richard Watts 22, Peter Merkel 18 and Peter C. Grayson 23, 1National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 2Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, 3University of Oxford, Oxford, United Kingdom, 4University of South Florida, Tampa, FL, 5Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, Canada, 6Cleveland Clinic Foundation, Cleveland, OH, 7McMaster University, Hamilton, ON, Canada, 8University of Utah Hospital, Salt Lake City, UT, 9Cleveland Clinic, Cleveland, OH, 10Henry Ford Hospital, Wayne State University, Detroit, MI, 11University of Pennsylvania - VCRC Project Manager, Philadelphia, PA, 12Brigham and Women's Hospital, Boston, MA, 13University of Pittsburgh, PITTSBURGH, PA, 14Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, 15Georgetown University Hospital/National Institutes of Health, Washington, DC, 16Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, 17Johns Hopkins Medicine, Baltimore, MD, 18University of Pennsylvania, Philadelphia, PA, 19Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, 20Mayo Clinic Rochester, Rochester, MN, 21Mayo Clinic College of Medicine, Rochester, MN, 22Norwich Medical School, University of East Anglia, Norwich, United Kingdom, 23National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD

    Background/Purpose: Current classification criteria differentiate between Takayasu’s arteritis (TAK) and giant cell arteritis (GCA), the two most common forms of large-vessel vasculitis, based primarily on…
  • Abstract Number: 2922 • 2019 ACR/ARP Annual Meeting

    Imaging Acquisition Technique Influences Interpretation of Positron Emission Tomography Vascular Activity in Large-Vessel Vasculitis

    Kaitlin Quinn1, Joel S. Rosenblum 2, Casey A. Rimland 3, K Bates Gribbons 4, Mark A. Ahlman 5 and Peter C. Grayson 6, 1Georgetown University Hospital/National Institutes of Health, Washington, DC, 2National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, 3National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, 4National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 5Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, 6National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD

    Background/Purpose: 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) is one of several imaging modalities used in the assessment of patients with large-vessel vasculitis (LVV).  Conventionally PET…
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