Abstracts tagged "Knee"

Abstract Number: 1395 • 2018 ACR/ARHP Annual Meeting
Could the Shortening of the Electronic Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) Questionnaire Improve Its Metric Properties?
Maud Wieczorek¹, Christine Rotonda¹, Jonathan Epstein^1,2, Francis Guillemin^1,2 and Anne-Christine Rat^1,3, ¹Université de Lorraine, EA4360, APEMAC, Nancy, France, ²Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ³Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: The aim of this study was to assess the validity of a short version of the electronic OAKHQOL questionnaire in a combined analysis with…
Abstract Number: 420 • 2018 ACR/ARHP Annual Meeting
Accelerated Knee Osteoarthritis Is Characterized By Destabilizing Meniscal Tears and Pre-Radiographic Structural Disease Burden
Jeffrey B. Driban¹, Julie Davis², Bing Lu³, Lori Lyn Price^4,5, Robert J. Ward⁶, James MacKay⁷, Charles B. Eaton⁸, Grace H. Lo⁹, Mary Barbe¹⁰, Ming Zhang¹¹, Jincheng Pang¹², Alina Stout¹³, Matthew Harkey¹³ and Timothy E. McAlindon¹⁴, ¹Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, ²Rheumatology, Tufts Medical Center, BOSTON, MA, ³Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁶Radiology, Tufts Medical Center, Boston, MA, ⁷Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁸Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁹Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ¹⁰Temple University School of Medicine, Philadelphia, PA, ¹¹Tufts Medical Center, Boston, MA, ¹²Electrical Engineering, Tufts University, Medford, MA, ¹³Rheumatology, Tufts Medical Center, Boston, MA, ¹⁴Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A subset of adults who develop knee osteoarthritis (KOA) quickly progress from no radiographic disease to advanced-stage disease often in ≤12 months. Adults with…
Abstract Number: 956 • 2018 ACR/ARHP Annual Meeting
Bone Mineral Density Is a Causal Risk Factor for Knee and Hip Osteoarthritis: A Population-Based and Mendelian Randomization Study in the UK Biobank
Thomas Funck-Brentano¹, Maria Nethander², Sofia Moverare Skrtic¹, Pascal Richette³ and Claes Ohlsson¹, ¹Center for Bone and Arthritis Research, Department of Internal Medicine, Sahlgrensaka Academy, Gothenburg University, Gothenburg, Sweden, ²Bioinformatics Core Facility, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden, ³Lariboisière Hospital, Lariboisière, University of Paris 7, Paris, France
Background/Purpose: Osteoarthritis (OA) involves the whole joint, with alterations of cartilage, synovium and bone. Whether bone changes are a cause or consequence of the disease…
Abstract Number: 1947 • 2018 ACR/ARHP Annual Meeting
Do Changes in Pain Sensitization and Depressive Symptoms Mediate the Effect of Extreme Weight Loss on Knee Pain Improvement?
S. Reza Jafarzadeh¹, Tuhina Neogi¹, Joshua J. Stefanik², Margaret M. Clancy¹, Jing-Sheng Li³ and David T. Felson¹, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Department of Physical Therapy, University of Delaware, Newark, DE, ³College of Health and Rehabilitation Sciences: Sargent College, Boston University, Boston, MA
Background/Purpose: We previously showed that the one-year effects of weight loss on knee pain reduction were not mediated by changes in structural features of osteoarthritis…
Abstract Number: 423 • 2018 ACR/ARHP Annual Meeting
Accelerated Knee Osteoarthritis Is Characterized By Pre-Radiographic Degeneration of the Extensor Mechanism and Cruciate Ligaments: Data from the Osteoarthritis Initiative
Julie Davis¹, Matthew Harkey¹, Robert J. Ward², James MacKay³, Lori Lyn Price^4,5, Charles B. Eaton⁶, Grace H. Lo⁷, Mary Barbe⁸, Timothy E. McAlindon⁹ and Jeffrey B. Driban¹⁰, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Radiology, Tufts Medical Center, Boston, MA, ³Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁶Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁷Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ⁸Temple University School of Medicine, Philadelphia, PA, ⁹Division of Rheumatology, Tufts Medical Center, Boston, MA, ¹⁰Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Degeneration of knee ligaments and tendons, which may be signs of joint instability and abnormal joint loading, may antedate the onset of radiographic accelerated…
Abstract Number: 957 • 2018 ACR/ARHP Annual Meeting
Biomechanical Therapy for Osteoarthritis of the Knee: A Randomized Controlled Trial
Stephan Reichenbach^1,2, Sarah Heldner¹, Armando Lenz³, David T. Felson⁴ and Peter Jüni⁵, ¹Institute for Social and Preventive Medicine, Bern, Bern, Switzerland, ²Department of Rheumatology, Immunology and Allergology, Bern, Bern, Switzerland, ³CTU Bern, University of Bern, Bern, Switzerland, ⁴Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Applied Health Research Centre (AHRC), Toronto, Toronto, ON, Canada
Background/Purpose: Biomechanics plays an important role in knee osteoarthritis (OA). A new biomechanical footwear system aims at altering knee loading patterns and retraining neuromuscular control…
Abstract Number: 1948 • 2018 ACR/ARHP Annual Meeting
Beliefs and Preferences for Reducing Sedentary Time in Those with Current or Past Knee Symptoms
Christine Pellegrini^1,2, Sara Powell², Chelsea Larsen² and Siobhan Phillips³, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Exercise Science, University of South Carolina, Columbia, SC, ³Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Physical activity is beneficial for those with current or previous knee symptoms, yet few meet federal physical activity guidelines. Reducing sedentary time, which has…
Abstract Number: 426 • 2018 ACR/ARHP Annual Meeting
The Association of Dietary Patterns with Knee Symptoms and MRI Detected Structures in Patients with Knee Osteoarthritis (OA)
Shuang Zheng¹, Feitong Wu¹, Flavia Cicuttini², Anita E Wluka², Dawn Aitken¹, Tania Winzeberg^1,3, Leigh Blizzard¹, Graeme Jones⁴ and Changhai Ding^1,5, ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, ³Faculty of Health, University of Tasmania, Hobart, Australia, ⁴Menzies Institute for Medical Research, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁵Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, China
The association of dietary patterns with knee symptoms and MRI detected structures in patients with knee osteoarthritis (OA)Abstract Background/Purpose: This study aimed to examine the…
Abstract Number: 1133 • 2018 ACR/ARHP Annual Meeting
Factors for Opioids Use in the Early Treatment Options for the Knee Osteoarthritis Patients
Soo-Kyung Cho¹, Seongmi Choi², Seul Gi Im², Hyoungyoung Kim¹, Sun-Young Jung³, Eun Jin Jang⁴ and Yoon-Kyoung Sung⁵, ¹Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), ²Statistics, Kyungpook National University, Daegu, Korea, Republic of (South), ³College of Pharmacy, Chung-Ang University, Seoul, Korea, Republic of (South), ⁴Information Statistics, Andong National University, Andong-si, Korea, Republic of (South), ⁵Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South)
Background/Purpose: Current guidelines for osteoarthritis (OA) treatment recommend a range of nonpharmacological and pharmacological interventions to alleviate pain, improve function and quality of life. Most…
Abstract Number: 1954 • 2018 ACR/ARHP Annual Meeting
Factors Associated with Overweight or Obesity in Athletes 5 Years after Anterior Cruciate Ligament Injury
Louise Thoma¹, Jessica Johnson², Daniel White³, May Arna Risberg^4,5 and Lynn Snyder-Mackler², ¹Physical Therapy, University of Delaware, Newark, DE, ²Physical Therapy; Biomechanics and Movement Science, University of Delaware, Newark, DE, ³Department of Physical Therapy, University of Delaware, Newark, DE, ⁴Norwegian Research Center for Active Rehabilitation, Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway, ⁵Division of Orthopedic Surgery, Oslo University Hospital, Oslo, Norway
Background/Purpose: Obesity and knee injury, including anterior cruciate ligament (ACL) rupture, are strong risk factors for the development of knee osteoarthritis. Identifying participant and post-injury…
Abstract Number: 427 • 2018 ACR/ARHP Annual Meeting
One Year Efficacy and Safety of One or Three Injections of Hylan G-F 20 for Knee Osteoarthritis: A Systematic Literature Review and Meta-Analysis
Orazio De Lucia¹, Georgios Filippou², Joerg Jerosch³, Sophie Yoon⁴, Jean-Francois Bitsch⁴, Tobias Sayre⁴ and Wilson Ngai⁵, ¹Division of Clinical Rheumatology, G. Pini Hospital, Milan, Italy, ²Section of Rheumatology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy, ³Department of Orthopedic Surgery, Johanna-Etienne Krankenhaus, Neuss, Germany, ⁴Doctor Evidence, Santa Monica, CA, ⁵Global Medical Affairs, General Medicines and Emerging Markets, Sanofi, Bridgewater, NJ
Background/Purpose: Hylan G-F 20 is indicated for the treatment of pain in knee osteoarthritis (OA) in patients who failed to respond adequately to conservative nonpharmacologic…
Abstract Number: 1134 • 2018 ACR/ARHP Annual Meeting
Some Is Better Than None: Minimum Physical Activity Threshold to Prevent Disability in Older Adults with Lower Extremity Joint Symptoms
Dorothy D. Dunlop¹, Jing Song¹, Jennifer M. Hootman², Julia (Jungwha) Lee³, Michael C. Nevitt⁴, Leena Sharma⁵, Pamela Semanik⁶, Charles B. Eaton⁷, C. Kent Kwoh⁸, Marc C. Hochberg⁹, Rebecca D. Jackson¹⁰ and Rowland W. Chang¹¹, ¹Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ³Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁵Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶College of Nursing, Rush University, Chicago, IL, ⁷Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁸Medicine, Division of Rheumatology, University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, ⁹University of Maryland School of Medicine, Baltimore, MD, ¹⁰Ohio State University, Columbus, OH, ¹¹Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: This study evaluated physical activity and sedentary times to identify an evidence-based threshold related to remaining free of disability over 4 years among adults…
Abstract Number: 1955 • 2018 ACR/ARHP Annual Meeting
Race Is Associated with Discharge Disposition after Total Knee Arthroplasty (TKA), Which Is Associated with 90-Day Readmission Rate
Jasvinder A. Singh¹, Michael Kallan² and Said Ibrahim³, ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Pennsylvania, Philadelphia, PA, ³Cornell University, New York, NY
Background/Purpose: To assess whether race/ethnicity is associated with differences in discharge disposition after elective primary total knee arthroplasty (TKA), and if discharge disposition is associated…
Abstract Number: 428 • 2018 ACR/ARHP Annual Meeting
Significant Pain Reduction with Oral Methotrexate in Knee Osteoarthritis; Results from a Randomised Controlled Phase III Trial of Treatment Effectiveness
Sarah R. Kingsbury¹, Puvan Tharmanathan², Ada Keding², Belen Corbacho², Fiona E Watt³, David L Scott⁴, Edward Roddy⁵, Fraser Birrell⁶, Nigel K Arden⁷, Catherine Arundel², Sarah Ronaldson², Lema Vernon⁸, Catherine Hewitt², Michael Doherty⁹, David Torgerson² and Philip G. Conaghan¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds, United Kingdom, Leeds, United Kingdom, ²York Trials Unit, University of York, York, United Kingdom, ³Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, ⁴Department of Rheumatology, King's College London, London, United Kingdom, ⁵Staffordshire and Stoke on Trent Partnership NHS Foundation Trust, Newcastle Under Lyme, United Kingdom, ⁶Northumbria Healthcare NHS Foundation Trust, North Shields, United Kingdom, ⁷Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, University of Oxford, Oxford, United Kingdom, ⁸Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁹The University of Nottingham, Nottingham, United Kingdom
Background/Purpose: Current treatments for osteoarthritis (OA) are severely limited. Synovitis is prevalent in OA and is associated with pain. The slow-acting anti-rheumatic drug methotrexate (MTX)…
Abstract Number: 1138 • 2018 ACR/ARHP Annual Meeting
Public Health Impact of Physical Inactivity in the Knee OA Population in the US
Elena Losina¹, Genevieve S. Silva², Karen C. Smith², Jamie E. Collins³, David J. Hunter⁴, Swastina Shrestha², Stephen P. Messier⁵, Edward H. Yelin⁶, Lisa Gale Suter⁷, A. David Paltiel⁸ and Jeffrey N. Katz⁹, ¹Orthopedics, Brigham and Women's Hospital, BU School of Public Health and Harvard Medical School, Boston, MA, ²Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ³Department of Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁵Department of Health and Exerc, Wake Forest University, Winston-Salem, NC, ⁶Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ⁷Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT, ⁸Yale University, New Haven, CT, ⁹Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: The benefits of physical activity (PA) in persons with OA are well-documented: PA reduces OA pain, improves mental health, and reduces the risk of…

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