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Abstracts tagged "juvenile idiopathic arthritis (JIA)"

  • Abstract Number: 2396 • 2018 ACR/ARHP Annual Meeting

    Reduction in the Utilization of Prednisone and/or Methotrexate Following the Initiation of Etanercept in Pediatric Patients

    Majed M M Khraishi1, Brad Millson2, John Woolcott3, Lisa Marshall4 and Heather Jones4, 1Memorial University of Newfoundland, St John's, NF, Canada, 2IQVIA, Kanata, ON, Canada, 3Global Outcomes & Evidence, Pfizer, Collegeville, PA, 4Pfizer, Collegeville, PA

     Background/Purpose: In Canada, the pediatric indications of etanercept (ETN) are active ankylosing spondylitis (AS), plaque psoriasis (PsO) and moderate to severely active juvenile idiopathic arthritis…
  • Abstract Number: 2398 • 2018 ACR/ARHP Annual Meeting

    Children with Enthesitis Have Worse Quality of Life, Function, and Pain, Irrespective of Their Juvenile Arthritis Category

    Dax G. Rumsey1, Jaime Guzman2, Alan Rosenberg3, Adam Huber4, Rosie Scuccimarri5, Natalie J. Shiff6, Alessandra Bruns7, Brian M. Feldman8 and Dean Eurich9, 1Paediatrics, University of Alberta, Edmonton, AB, Canada, 2Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 3Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, 4Dalhousie University, Halifax, NS, Canada, 5Department of Pediatrics, McGill University Health Centre, Montreal, QC, Canada, 6University of Florida, Gainesville, FL, 7Hospitalier de l’Universite de Sherbrooke, Sherbrooke, QC, Canada, 8Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 9University of Alberta, Edmonton, AB, Canada

    Background/Purpose: To estimate the impact of enthesitis on patient reported outcomes (PROs) in children with juvenile idiopathic arthritis (JIA), irrespective of their JIA category. Methods:…
  • Abstract Number: 2400 • 2018 ACR/ARHP Annual Meeting

    Validating and Developing a Selected Questionnaire to Predict Early Diagnosis of Juvenile Idiopathic Arthritis in German Population

    Tristan Scheer1, Jens Klotsche2, Claudio A. Len3 and Ivan Foeldvari4, 1Asklepios Campus Hamburg, Semmelweis University Budapest, Hamburg, Germany, 2Program Area Epidemiology, German Rheumatism Research Center, Berlin, Germany, 3Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Universidade Federal de São Paulo), São Paulo,, Brazil, 4Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic inflammatory rheumatologic disease in children and adolescents with a prevalence of 1:1000 children in Germany.…
  • Abstract Number: 2403 • 2018 ACR/ARHP Annual Meeting

    The Therapeutic Alliance Is Associated with a Better Therapeutic Adherence in Children with Juvenile Idiopathic Arthritis: Results of a French Multicenter Study

    Valérie Devauchelle-Pensec1, Anne Lohse2, Francis Guillemin3, Elisabeth Solau-Gervais4, Linda Rossi-Semerano5, Agnès Duquesne6, Irène Lemelle7, Pascal Pillet8, Claire Ballot9, Laurence Goumy10, Tu Anh Tran11, Laeticia Sparsa12, Heloise Reumaux13, Anaïs Arbault14 and Camille Alleyrat15, 1Rheumatology, CHU Brest, Brest, France, 2Rheumatology Department, Hopital Nord Franche Comté, Belfort, France, 3Université de Lorraine, EA4360, APEMAC, Nancy, France, 4Service de Rhumatologie, CHRU de Poitiers, Poitiers, France, 5Paediatric Rheumatology, Hôpital Kremlin Bicêtre, PARIS, France, 64Department of Nephrology-Rheumatology-Dermatology Pediatric - Rheumatology, Hopital Femme-Mère-Enfant, Bron, France, 7Department of pediatric onco-hematology, CHU de Nancy - Hôpitaux de Brabois,, Vandœuvre-Lès-Nancy, France, 8Paediatrics, Hôpital Pellegrin, University Hospital of Bordeaux, Bordeaux, France, 9Department of Pediatric Rheumatology, Hôpital Jean-Minjoz, Besançon, France, 10Pediatric, CHU d'Angers, Angers, France, 11Paediatrics, University Hospital, Nîmes, Nîmes, France, 12Rheumatology, Hopital Emile Muller, Mulhouse, France, 13Pediatric Rheumatology, CHRU Lille, Lille, France, 14Rheumatology, CHU de Dijon, Dijon, France, 15134 Inserm CIC-1433 Clinical Epidemiology, CHRU de Nancy, Hôpitaux de Brabois, Nancy, France

    Background/Purpose: The therapeutic compliance (TC) is a major issue for the management of Juvenile Idiopathic Arthritis (JIA). The chronic nature of this inflammatory rheumatism requires…
  • Abstract Number: 2404 • 2018 ACR/ARHP Annual Meeting

    Quality of Life Assessment in Juvenile Idiopathic Arthritis: A Single Center Assessment

    W. Blaine Lapin1, Taylor Phillips2, Danielle Guttman-Lapin3, Amanda Brown4, Eyal Muscal5 and Filiz O. Seeborg1, 1Department of Pediatrics, Division of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, 2Rice University, Houston, TX, 3Aldine Independent School District, Aldine, TX, 4Department of Pediatrics, Division of Allergy, Immunology and Rheumatology, Baylor College of Medicine, houston, TX, 5Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Houston, TX

    Background/Purpose: Patients with Juvenile Idiopathic Arthritis (JIA) face physical, social, and emotional issues that affect their quality of life. Health-related quality of life (HRQoL) is…
  • Abstract Number: 2405 • 2018 ACR/ARHP Annual Meeting

    Health-Related Quality of Life, Functioning, and Mental Health of Children with Chronic Non-Infectious Uveitis

    Joseph McDonald1, Curtis Travers2, Courtney McCracken2, Steven Yeh3, Kelly A. Rouster-Stevens4, Patricia Vega-Fernandez4, Elaine Ramsay4, Sampath Prahalad4, Carolyn Drews-Botsch5 and Sheila Angeles-Han6, 1Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Pediatrics, Emory University School of Medicine, Atlanta, GA, 3Ophthalmology, Emory University School of Medicine, Atlanta, GA, 4Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, 5Epidemiology, Emory University School of Public Health, Atlanta, GA, 6Rheumatology, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH

    Background/Purpose: Pediatric chronic non-infectious uveitis can lead to ocular complications and vision loss. The ophthalmic clinical exam is primarily used to assess uveitis outcomes but…
  • Abstract Number: 2407 • 2018 ACR/ARHP Annual Meeting

    New Onset of Uveitis in Non-Methotrexate Group, Methotrexate Group and Etanercept Group in Juvenile Idiopathic Arthritis

    Mikhail Kostik, Ekaterina Gaidar, Maria Likhacheva, Eugenia Isupova, Irina Chikova, Margarita Dubko, Vera Masalova, Tatiana Likhacheva, Ludmila Snegireva, Tatiana Kornishina, Olga Kalashnikova and Vyacheslav Chasnyk, Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russian Federation

    Background/Purpose: Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA), often entirely asymptomatic but could be sight-threatening. The most often prescribed biologics…
  • Abstract Number: 2409 • 2018 ACR/ARHP Annual Meeting

    Do Children with Juvenile Idiopathic Arthritis Play an Active Role in Their Treatment Adherence? First Results of the Rumaji Study

    Guillaume Montagu1, Ellie Mevel1, William FAHY2, Linda Rossi-Semerano3, Elisabeth Solau-Gervais4, Sonia Tropé5 and Jean-David Cohen6, 1Research, Unknowns, strategy and innovation consulting, PARIS, France, 2KOURIR, Paris, France, 3Paediatric Rheumatology, Hôpital Kremlin Bicêtre, PARIS, France, 4Service de Rhumatologie, CHRU de Poitiers, Poitiers, France, 5149 avenue du Maine, ANDAR, Paris, France, 6IMMUNO-RHEUMATOLOGY, CHU LAPEYRONIE, MONTPELLIER, France

    Background/Purpose: Adherence to DMARDs such as methotrexate and biologics is critical for patients with Juvenile Idiopathic Arthritis (JIA). Notwithstanding, few studies exists on that topic…
  • Abstract Number: 979 • 2018 ACR/ARHP Annual Meeting

    Stopping Medicines for Inactive Juvenile Idiopathic Arthritis: What Do Patients and Families Consider?

    Daniel B. Horton1,2, Jomaira Salas3, Aleksandra Wec4, Timothy Beukelman5, Alexis Boneparth6, Jaime Guzman7, Ky Haverkamp8, Melanie Kohlheim9, Melissa L. Mannion5, Nandini Moorthy1, Elizabeth Stringer10, Lori Tucker7, Sarah Ringold11 and Marsha Rosenthal2, 1Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 2Rutgers Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, 3Department of Sociology, Rutgers, the State University of New Jersey, New Brunswick, NJ, 4Mathematica Policy Research, Princeton, NJ, 5Pediatrics, University of Alabama at Birmingham, Birmingham, AL, 6Pediatrics, Columbia University Medical Center, New York, NY, 7Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 8Family Medicine, University of Washington School of Medicine, Seattle, WA, 9Pediatric Rheumatology Care and Outcomes Improvement Network, Cincinnati, OH, 10IWK Health Centre, Dalhousie University, Halifax, NS, Canada, 11Pediatrics, Seattle Children's Hospital, Seattle, WA

    Background/Purpose: Prior research has focused on factors important to clinicians in decisions about withdrawing JIA therapy. Based on recent interviews with patients and caregivers about…
  • Abstract Number: 2420 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcome and Perinatal Complications of Neonate Born to Mothers with Juvenile Idiopathic Arthritis in Asia

    Chao-Yi Wu1, Shang-Chun Changchien2, Huang-Yu Yang3, Kuo-Wei Yeh4 and Jing-Long Huang1,2, 1Division of Allergy, Asthma and Rheumatology. Department of Pediatrics, Chang-Gung Memorial Hospital, Taoyuan city, Taiwan, 2Medicine, Chang-Gung University, Taoyuan city, Taiwan, 3Department of Nephrology,, Chang-Gung Memorial Hospital, Taoyuan city, Taiwan, 4Division of Allergy, Asthma and Rheumatology. Department of Pediatrics, Chang-Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the leading pediatric rheumatic disease affecting 30 out of a million women. Although spontaneous remission may occur in most…
  • Abstract Number: 1849 • 2018 ACR/ARHP Annual Meeting

    Remission Status after 18 Years of Follow-up in the Population-Based Nordic Juvenile Idiopathic Arthritis (JIA) Cohort

    Mia Glerup1, Veronika Rypdal2,3, Ellen Dalen Arnstad4,5, Maria Ekelund6,7, Suvi Peltoniemi8, Kristiina Aalto8, Marite Rygg9,10, Peter Toftedal11, Susan Nielsen11, Anders Fasth12, Lillemor Berntson13, Ellen Nordal14,15 and Troels Herlin16, 1Department of Pediatrics, Dept. of Pediatrics, Aarhus University Hospital, Denmark, Aarhus, Denmark, 2Dept. of Clin. Med, UIT The Arctic University of Norway, Tromsø, Norway, 3Dept. of Pediatrics, University Hospital of North Norway, Tromsø, Norway, 4Dept. Clin. and Mol. Med., NTNU, Norway, Trondheim, Norway, 5Dept. of Pediatrics, Levanger Hospital, Nord-Trøndelag, Norway, Trondheim, Norway, 6Department of Pediatrics, Dept. of Pediatrics, Ryhov County Hospital, Jonkoping, Sweden, Jonkoping, Sweden, 7Uppsala University, Uppsala, Sweden, Jonkobing, Sweden, 8Hospital for Children and Adolescents, University of Helsinki, Finland, Helsinki, Finland, 9Dep. Clin. and Mol. Med., Dept. Clin. and Mol. Med., NTNU, Norway, Trondheim, Norway, 10Department of Pediatrics, Dept. of Pediatrics, St. Olavs Hospital, Norway, Trondheim, Norway, 11Department of Pediatrics, Dept. of Pediatrics, Copenhagen University Hospital, Denmark, Copenhagen, Denmark, 12Sahlgrenska Academy, University of Gothenburg, Sweden, Gothenburg, Sweden, 13Uppsala University, Uppsala, Sweden, Uppsala, Sweden, 14Departments of Pediatrics, Dept. of Pediatrics, University Hospital of North Norway, Tromsø, Norway, 15Department of Clinical Medicine, Dept. of Clin. Med, UIT The Arctic University of Norway, Tromsø, Norway, 16Dept. of Pediatrics, Aarhus University Hospital, Aarhus N, Denmark

    Background/Purpose: Innovative changes towards targeted treatment have improved the outcome dramatically for juvenile idiopathic arthritis (JIA) but the question remains how well these patients perform…
  • Abstract Number: 2916 • 2018 ACR/ARHP Annual Meeting

    New JADAS10- and cJADAS10-Based Cutoffs for Juvenile Idiopathic Arthritis Disease Activity States: Validation in a Multinational Dataset of 4830 Patients

    Alessandro Consolaro1,2, Chiara Trincianti1, Pieter van Dijkhuizen3, Giedre Januskeviciute4, Gabriella Giancane5, Alessandra Alongi1, Joost Swart3, Nicola Ruperto6,7 and Angelo Ravelli2,8, 1University of Genova, Genova, Italy, 2Clinica Pediatrica - Reumatologia, Istituto Giannina Gaslini, Genova, Italy, 3UMC Utrecht, Wilhelmina Children’s Hospital, Utrecht, Netherlands, 4Istituto Giannina Gaslini, Genova, Italy, 5Clinica Pediatrica - Reumatologia, Istituto Giannina Gaslini, Genoa, Italy, 6Universita di Genova Pediatria II, Genova, Italy, 7Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, 8University of Genova, Genoa, Italy

    Background/Purpose: The Juvenile Arthritis Disease Activity Score (JADAS) and its clinical version excluding the acute phase reactant (cJADAS) were developed for measuring disease activity in…
  • Abstract Number: 2017 • 2018 ACR/ARHP Annual Meeting

    Oral Microbiota in New-Onset Juvenile Idiopathic Arthritis

    Albert Chow1,2,3, Sriharsha Grevich1,2,3, Peggy Lee4, Jeffrey McLean4, Sarah Ringold1,3,5, Roger Bumgarner6 and Anne Stevens1,2,3, 1Pediatrics, University of Washington, Seattle, WA, 2Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 3Pediatric Rheumatology, Seattle Children's Hospital, Seattle, WA, 4Dentistry, University of Washington, Seattle, WA, 5Center for Clinical and Translational Research, Seattle Children's Research Institute, Seattle, WA, 6Microbiology, University of Washington, Seattle, WA

    Background/Purpose: Oral microbial dysbiosis of specific organisms such as Porphyromonas, Aggregatibacter, Tannerella, and Treponema in dental plaque has been implicated in the pathogenesis of adult…
  • Abstract Number: 2918 • 2018 ACR/ARHP Annual Meeting

    Physical Activity in Canadian Children with Juvenile Idiopathic Arthritis: The LEAP Study (Linking Exercise, Activity, and Pathophysiology in Canadian Children with Arthritis)

    Lori Tucker1, Jaime Guzman1, Kristin Houghton2, Dax G. Rumsey3, Elizabeth Stringer4, Shirley M.L. Tse5, Rosie Scuccimarri6, Claire LeBlanc7, Roberta Berard8, Bianca Lang9, Karen N Watanabe Duffy10 and Ciarán M. Duffy11, 1BC Children's Hospital, Vancouver, BC, Canada, 2Rheumatology/Pediatrics, British Columbia Children's Hospital, Vancouver, BC, Canada, 3Stollery Children's Hospital, Edmonton, AB, Canada, 4Department of Rheumatology, IWK Health Centre, Halifax, NS, Canada, 5The Hospital for Sick Children, Toronto, ON, Canada, 6Department of Pediatrics, McGill University Health Centre, Montreal, QC, Canada, 7Pediatrics, Montreal Children's Hospital, Montreal, QC, Canada, 8Pediatrics, Children's Hospital, London Health Sciences Centre, London, ON, Canada, 9Pediatrics, IWK Health Centre, Halifax, NS, Canada, 10Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, 11Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada

    Background/Purpose: Physical activity (PA) is an important component of health, and is essential for optimal growth and development. Children with juvenile idiopathic arthritis (JIA) are…
  • Abstract Number: 2018 • 2018 ACR/ARHP Annual Meeting

    Microenvironment Driven Re-Shaping of Pathogenic T Effector and Regulatory Subset in Active Juvenile Idiopathic Arthritic Patients

    Jing Yao Leong1, Pavanish Kumar1, Phyllis Chen2, Joo Guan Yeo2,3, Camillus Chua2, Sharifah Nur Hazirah2, Suzan Saidin1, Thaschawee Arkachaisri2,3, Alessandro Consolaro4, Marco Gattorno5, Alberto Martini6 and Salvatore Albani2, 1Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre, Singapore, Singapore, 2Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre, Singapore Health Services Pte Ltd, Singapore, Singapore, 3KK Women's and Children's Hospital, Singapore, Singapore, 4Second Paediatric Division, University of Genoa and G Gaslini Institute, Genova, Italy, Genova, Italy, 5Second Paediatric Division, University of Genoa and G Gaslini Institute, Genova, Italy, Genoa, Italy, 6Pediatric Rheumatology International Trial Organization (PRINTO) Coordinating Centre, Genoa, Italy

    Background/Purpose: We have previously identified two CD4 pathogenic circulatory subsets in both T effector (CPLs) and T regulatory (iaTreg) compartments that are both HLA-DR+, antigen…
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