Abstracts tagged "Imaging"

Abstract Number: 760 • 2018 ACR/ARHP Annual Meeting
Diagnosing SLE Arthritis with Dynamic Diffuse Optical Spectroscopy
George Danias¹, Youngwan Kim², Alessandro Marone³, Kayla Neville¹, Andrea Frantz¹, Teja Kapoor⁴, Laura Geraldino-Pardilla¹, Ioannis Kymissis², Andreas Hielscher^2,3,5 and Anca Askanase¹, ¹Rheumatology, Columbia University Medical Center, New York, NY, ²Electrical Engineering, Columbia University, New York, NY, ³Biomedical Engineering, Columbia University, New York, NY, ⁴Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ⁵Radiology, Columbia University Medical Center, New York, NY
Background/Purpose: SLE arthritis is difficult to evaluate because of the sometimes-evanescent nature of the symptoms and limitations of physical exams and imaging studies. Dynamic diffuse…
Abstract Number: 2235 • 2018 ACR/ARHP Annual Meeting
Monosodium Urate Deposition Distribution in the Knees, Hands, and Feet of Treated Gout Patients: A Dual-Energy CT Study
Chio Yokose¹, Nicola Dalbeth², Savvas Nicolaou³, Scott Baumgartner⁴, Jia Hu⁵, Maple Fung⁴, F. Joseph Simeone⁶ and Hyon K. Choi¹, ¹Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ²University of Auckland, Auckland, New Zealand, ³Radiology, University of British Columbia, Vancouver, BC, Canada, ⁴Formerly Ardea Biosciences, San Diego, CA, ⁵Heron Therapeutics, San Diego, CA, ⁶Department of Radiology, Massachusetts General Hospital, Boston, MA
Background/Purpose: Prior studies have demonstrated that monosodium urate (MSU) deposits on dual-energy CT (DECT) are commonly found in joints as well as tendons of the…
Abstract Number: 798 • 2018 ACR/ARHP Annual Meeting
Predominant Fasciitis and Mild Intramuscular Edema on Muscle Magnetic Resonance Imaging in Scleroderma-Associated Myopathy
Julie J. Paik¹, Shivani Ahlawat², Filippo DelGrande³, Laura K. Hummers⁴, Fredrick M. Wigley⁴, Ami A. Shah⁴, Andrew Mammen⁵ and Laura Fayad⁶, ¹Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Johns Hopkins University, Baltimore, MD, ⁴Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁵National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁶Radiology, Johns Hopkins University, Baltimore, MD
Background/Purpose: Skeletal myopathy in systemic sclerosis is poorly defined. The spectrum of muscle histopathology in systemic sclerosis has been previously studied and shown to be…
Abstract Number: 2924 • 2018 ACR/ARHP Annual Meeting
Spinal Radiographic Progression in Early Axial Spondyloarthritis: 5-Year Data from the DESIR Cohort
Sofia Ramiro¹, Désirée van der Heijde², Alexandre Sepriano³, Miranda van Lunteren⁴, Anna Molto⁵, Maria Antonietta D'Agostino⁶, Damien Loeuille⁷, Maxime Dougados⁸, M. Reijnierse⁹ and Pascal Claudepierre¹⁰, ¹Zuyderland Medical Center, Heerlen & Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Centre, Leiden, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ⁶Department of Rheumatology, Assistance publique-Hôpitaux de Paris Ambroise Paré Hospital, Boulogne-Billancourt , Université Versailles Saint Quentin en Yvelines, Paris, France, ⁷Rheumatology, University Hospital of Nancy, NANCY, France, ⁸Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁹Radiology, Leiden University Medical Center, Leiden, Netherlands, ¹⁰Hôpital Henri Mondor, Créteil, France
Background/Purpose: Spinal radiographic progression has been investigated in patients with r-axSpA, but not yet as thoroughly in early axSpA. We aimed to analyse the progression…
Abstract Number: 12L • 2017 ACR/ARHP Annual Meeting
Evaluation of Intravenous Injection of Tc 99m Tilmanocept in Static Planar Gamma Emission Imaging and Fused SPECT/CT Imaging for Rheumatoid Arthritis
Arash Kardan¹, Bonnie Abbruzzese², James Sanders², Allison Kissling², David Ralph², Joanna Shuping², Michael Blue², Carley Hartings², Rachael Hershey², Ahmad Ismail², Izabela Gierach², Hannah Bailey², Amelia Spaulding², Matthew Haynam², George Zubal³ and Frederick Cope², ¹Charles F. Kettering Memorial Hospital and Wright State University Boonshoft School of Medicine, Dayton, ND, ²Navidea Biopharmaceuticals, Inc., Dublin, OH, ³Z-Concepts, LLC, East Haven, CT

Background/Purpose: Activated macrophages play a critical role in RA by perpetuating inflammation via TNFα release and participating in the destruction of bone and cartilage. Notably,…
Abstract Number: 582 • 2017 ACR/ARHP Annual Meeting
Low Dose Computed Tomography Detects More Progression of Bone Formation in Comparison to Conventional Radiography in Patients with Ankylosing Spondylitis
Anoek de Koning¹, Freek de Bruin², Rosaline van den Berg³, Sofia Ramiro⁴, Xenofon Baraliakos⁵, Jürgen Braun⁵, Floris van Gaalen³, M. Reijnierse⁶ and Désirée van der Heijde⁷, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²LUMC, Leiden, Netherlands, ³Rheumatology, LUMC, Leiden, Netherlands, ⁴Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ⁵Rheumazentrum Ruhrgebiet, Herne, Germany, ⁶Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁷Leiden University Medical Center, Leiden, Netherlands
Background/Purpose : A newly developed scoring method for low dose CT (ldCT) of the whole spine, CT Syndesmophyte Score (CTSS), has shown good inter-reader reliability…
Abstract Number: 1984 • 2017 ACR/ARHP Annual Meeting
The Cervical Spine in Fibromyalgia Patients: Loss of Lordotic Curve Is Characteristic of Fibromyalgia and Can Assist in the Diagnosis
Robert S. Katz¹, Alexandra Katz Small², Ben J Small³ and Anthony Farkasch⁴, ¹Rush University Medical Center, Chicago, IL, ²University of Illinois College of Medicine, Chicago, IL, ³Rheumatology, University of Illinois at Chicago Medical School, Chicago, IL, ⁴Rheumatology Associates S.C., Chicago, IL
Background/Purpose: Patients with fibromyalgia have widespread pain. We have found that a lateral view of a cervical spine radiograph frequently identifies a loss of the…
Abstract Number: 589 • 2017 ACR/ARHP Annual Meeting
Erosions at the Sacroiliac Joints and Fatty Lesions at the Spine Are the Most Discriminant Lesions for Recent Onset Axial Spondyloarthritis Recognition
Anna Molto¹, Laure Gossec², Violaine Foltz², Romain Beaufort³, Jean Denis Laredo⁴, Pascal Richette⁵, Philippe Dieude⁶, Philippe Goupille⁷, Antoine Feydy⁸ and Maxime Dougados⁹, ¹Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ²UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ³Private Practice,, Paris, France, ⁴Radiology Department, Lariboisière Hospital, Paris, France, ⁵Rheumatology Department, Université Paris Diderot, Paris, France, ⁶Université Paris-Diderot, Paris, France, ⁷Department of Rheumatology, CHRU de Tours; and Université François-Rabelais de Tours, Tours, France, ⁸Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁹Paris, Paris, France
Background/Purpose: only scarce data are available regarding the prevalence of MRI structural lesions of the sacroiliac joints (SIJ) or the spine suggestive of axial Spondyloarthritis…
Abstract Number: 1985 • 2017 ACR/ARHP Annual Meeting
Cervical Spine Radiographs in Fibromyalgia Patients Show Reduced Cobb Angle and Suggest the Presence of Increased Muscle Pressure As a Cause of the Illness
Robert S. Katz¹, Ben J Small², Alexandra Katz Small³ and Anthony Farkasch⁴, ¹Rush University Medical Center, Chicago, IL, ²Rheumatology, University of Illinois at Chicago Medical School, Chicago, IL, ³University of Illinois College of Medicine, Chicago, IL, ⁴Rheumatology Associates S.C., Chicago, IL
Background/Purpose: Fibromyalgia patients are reported to have a straight neck on lateral x-ray views of the cervical spine. We measured the Cobb angle in…
Abstract Number: 61 • 2017 ACR/ARHP Annual Meeting
Resolution of Systemic Joint Inflammatory Processes and Regeneration of Existing Bone Damage upon TNF Blockade As Monitored By In Vivo Multimodal PET-CT Imaging in Progressed Experimental Arthritis
Silvia Hayer¹, Markus Zeilinger^2,3, Volker Weiss^3,4, Markus Seibt⁵, Birgit Niederreiter¹, Tetyana Shvets⁶, Monika Dumanic⁶, Florian Pichler⁶, Marcus Hacker⁶, Josef S. Smolen⁷, Kurt Redlich⁸ and Markus Mitterhauser⁶, ¹Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Faulty of Engineering, University of Applied Sciences, Winer Neustadt, Austria, ³Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ⁴Faculty of Engineering, University of Applied Sciences, Wiener Neustadt, Austria, ⁵Department Internal Medicine III, Division Rheumatology, Medical University of Vienna, Vienna, Austria, ⁶Medical University of Vienna, Vienna, Austria, ⁷Medical University Vienna, Division of Rheumatology, Department of Internal Medicine III, Vienna, Austria, ⁸Division of Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: To use in vivo multimodal [18F]FDG (fluoro-D-glucose, tracer for inflammation) and [18F]Sodium Fluoride (bone tracer) positron emission tomography/computed tomography (PET-CT) imaging for the monitoring…
Abstract Number: 591 • 2017 ACR/ARHP Annual Meeting
Inflammation on MRI of Spine and Sacroiliac Joints Is Highly Predictive of Structural Damage in Axial Spondyloarthritis: The 5 Years Data of the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Robert B.M. Landewé³, Maxime Dougados⁴ and Désirée van der Heijde¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands, ⁴Paris-Descartes University,, Paris, France
Background/Purpose: The effect of local inflammation on structural damage in patients (pts) with axial spondyloarthritis is not well known. We aimed to test the possible…
Abstract Number: 2006 • 2017 ACR/ARHP Annual Meeting
Altered Microcirculation As a Proxy for Inflammation in Hand Osteoarthritis Can Reliably be Assessed Using Fluorescence Optical Imaging
Ida K. Haugen¹, Sigrid Hestetun¹, Benedict Drude², Gerd R. Burmester³, Tore K Kvien⁴ and Sarah Ohrndorf², ¹Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, ³Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, ⁴Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Previous studies in systemic inflammatory joint diseases have suggested that Fluorescence Optical Imaging (FOI) is a reliable and sensitive tool for the detection of…
Abstract Number: 179 • 2017 ACR/ARHP Annual Meeting
Mass Spectrometry Imaging of Synovium: A Novel Approach to Classify the Rheumatoid and Psoriatic Arthritis Patients
Beatriz Rocha^1,2, Berta Cillero-Pastor³, Gert Eijkel³, Lennart R. Huizing³, Cristina Ruiz-Romero^1,4, Andrea Cuervo^5,6, Ron M A Heeren³, Juan D. Cañete^5,6 and Francisco J Blanco^1,6, ¹Rheumatology Division, ProteoRed/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña, A Coruña, Spain, A Coruña, Spain, ²The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University, The Netherlands, Masstricht, Netherlands, ³The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University, The Netherlands, Maastricht, Netherlands, ⁴CIBER-BBN Instituto de Salud Carlos III, INIBIC-CHUAC, A Coruña, Spain., A Coruña, Spain, ⁵Arthritis Unit, Rheumatology Department, Hospital Clinic, IDIBAPS, Barcelona, Spain, Barcelona, Spain, ⁶RIER-RED de Inflamación y Enfermedades Reumáticas, INIBIC-CHUAC, A Coruña, Spain, A Coruña, Spain
Background/Purpose: Psoriatic arthritis (PsA) and Rheumatoid arthritis (RA) are immune-mediated chronic inflammatory diseases. Synovial membrane is the initial site of inflammation in PsA and RA…
Abstract Number: 593 • 2017 ACR/ARHP Annual Meeting
Progression of Structural Damage on MRI in Patients with Axial Spondyloarthritis Is Limited: The 5 –Year Results in the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Robert B.M. Landewé³, Maxime Dougados⁴ and Désirée van der Heijde¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands, ⁴Paris-Descartes University,, Paris, France
Background/Purpose: Reliably detecting radiographic structural change in patients with axial spondyloarthritis (axSpA), especially in the sacroiliac joints (SIJ), is notoriously difficult. Magnetic resonance imaging (MRI)…
Abstract Number: 2011 • 2017 ACR/ARHP Annual Meeting
Assessment of Methods to Quantitatively Evaluate Global Synovitis Activity with FDG-PET/CT
William Y. Raynor¹, Venkata S. Jonnakuti¹, Kaiyuan Zheng¹, Poul Flemming Høilund-Carlsen², Abass Alavi³ and Joshua Baker⁴, ¹Radiology, University of Pennsylvania, Philadelphia, PA, ²Nuclear Medicine, Odense University Hospital, Odense, Denmark, ³Department of Radiology/Division of Nuclear Medicine, University of Pennsylvania, Philadelphia, PA, ⁴Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Fluorodeoxyglucose (FDG)-positron emission tomography (PET) allows more direct assessment of inflammation than other imaging modalities by portraying metabolic activity. No standards exist for objective…

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