ACR Meeting Abstracts

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Abstracts tagged "Imaging"

  • Abstract Number: 316 • 2018 ACR/ARHP Annual Meeting

    Eligibility Rates in Axial Spondyloarthritis Clinical Trials Based on Imaging Criteria

    Farhan A. Syed1, David Bennett1, Michael O'Connor1, Gabriele Pradella2 and Sarah Warner1, 1Scientific and Medical Services, PAREXEL International, Billerica, MA, 2Image Management, PAREXEL International, Billerica, MA

    Background/Purpose: Axial Spondyloarthritis (AxSpA) encompasses both non-radiographic (nr-AxSpA) as well as radiographic ankylosing spondylitis (AS) which displays structural changes at the sacro-iliac joint (SIJ).  Phase…
  • Abstract Number: 2198 • 2018 ACR/ARHP Annual Meeting

    Evaluation of 18F-Fluorodeoxyglucose PET-CT Score at Baseline on the Therapeutic Response to Prednisone in Polymyalgia Rheumatica: A Retrospective Study

    Nicolas Giraud1, Maxime Sondag2, Aline Charpentier2, Hatem Boulahdour3, Clément Prati4,5, Daniel Wendling6,7 and Frank Verhoeven8, 1Rheumatology, CHU de Besançon, Besançon, France, 2rheumatology, CHU de Besançon, Besancon, France, 3CHU de Besançon, Besançon, France, 4EA 4267 FDE, FHU INCREASE, Université de Bourgogne Franche Comté, Besancon, France, 5Rheumatology, University Hospital - Bourgogne Franche Comté University, Besancon, France, 6Rheumatology, University Hospital - Bourgogne Franche Comté University, Besançon, France, 7EA 4266, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France, F-25000 Besançon, France, 8EA 4267 PEPITE, Université de Bourgogne Franche Comté, Besançon, France

    Background/Purpose: To evaluate the impact of 18F-fluorodeoxyglucose PET-CT (FDG-PET/CT) score at baseline, on the therapeutic response to prednisone, in patients with polymyalgia rheumatica (PMR). Methods:…
  • Abstract Number: 471 • 2018 ACR/ARHP Annual Meeting

    Early Signs of Diastolic Impairment in Children with Incident Systemic Lupus Erythematosus

    Joyce C. Chang1,2, Brian R. White3, Matthew D. Elias3, Rui Xiao4, Andrea M. Knight5,6,7, Pamela F. Weiss8,9,10 and Laura M. Mercer-Rosa3,7, 1Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 3Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, 4Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 5Center for Pediatric Clinical Effectiveness & PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, 6Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 7Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 8Center for Clinical Epidemiology and Biostastistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 9Division of Rheumatology, Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, 10Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The timing and etiology of diastolic impairment in pediatric-onset systemic lupus erythematosus (pSLE) are poorly understood, and the role of screening echocardiography remains unclear.…
  • Abstract Number: 2211 • 2018 ACR/ARHP Annual Meeting

    Technetium Tc 99m Tilmanocept: A Targeted Immunodiagnostic Radiopharmaceutical for the Assessment of Synovial Macrophage Activity in Rheumatoid Arthritis

    Arash Kardan1, Allison Kissling2, Bonnie Abbruzzese2, Ahmad Ismail2, Rachael Hershey2, Carley Hartings2, David Ralph2, Izabela Gierach2, Michael Blue2, Hannah Bailey2, Christopher Gablemann2, Katherine Repp2 and Frederick Cope2, 1Charles F. Kettering Memorial Hospital and Wright State University Boonshoft School of Medicine, Dayton, OH, 2Navidea Biopharmaceuticals, Inc., Dublin, OH

    Background/Purpose: Activated macrophages are a critical component of the inflammatory etiology of RA. It is well established that these macrophages perpetuate joint inflammation and destruction…
  • Abstract Number: 12L • 2017 ACR/ARHP Annual Meeting

    Evaluation of Intravenous Injection of Tc 99m Tilmanocept in Static Planar Gamma Emission Imaging and Fused SPECT/CT Imaging for Rheumatoid Arthritis

    Arash Kardan1, Bonnie Abbruzzese2, James Sanders2, Allison Kissling2, David Ralph2, Joanna Shuping2, Michael Blue2, Carley Hartings2, Rachael Hershey2, Ahmad Ismail2, Izabela Gierach2, Hannah Bailey2, Amelia Spaulding2, Matthew Haynam2, George Zubal3 and Frederick Cope2, 1Charles F. Kettering Memorial Hospital and Wright State University Boonshoft School of Medicine, Dayton, ND, 2Navidea Biopharmaceuticals, Inc., Dublin, OH, 3Z-Concepts, LLC, East Haven, CT

    Background/Purpose: Activated macrophages play a critical role in RA by perpetuating inflammation via TNFα release and participating in the destruction of bone and cartilage. Notably,…
  • Abstract Number: 294 • 2017 ACR/ARHP Annual Meeting

    DNA Area and Netosis Analysis (DANA): A High-Throughput Method to Quantify Neutrophil Extracellular Traps in Fluorescent Microscope Images

    Ryan Rebernick1, Lauren Fahmy2, Christopher Glover2, Nicole Rademacher2, Hemanth Potluri2, Mandar Bawadekar1, Christie M. Bartels3 and Miriam A. Shelef1,4, 1Department of Medicine, Division of Rheumatology, University of Wisconsin - Madison, Madison, WI, 2University of Wisconsin - Madison, Madison, WI, 3Rheumatology/Medicine, University of Wisconsin - Madison, Madison, WI, 4William S. Middleton Memorial Veterans Hospital, Madison, WI

    Background/Purpose: Neutrophil extracellular traps (NETs), extracellular structures composed of decondensed chromatin, are released in a process called NETosis. NETs, which are part of normal host…
  • Abstract Number: 1512 • 2017 ACR/ARHP Annual Meeting

    Is Sacroiliac Imaging the All-Decisive Factor in the Diagnosis of Early Axial Spondyloarthritis? Data from the Spondyloarthritis Caught Early (SPACE) Cohort

    Zineb Ez-Zaitouni1, Robert B.M. Landewé2, Miranda van Lunteren1, Pauline Bakker1, Karen M Fagerli3, Roberta Ramonda4, Lennart TH Jacobsson5, Désirée van der Heijde6 and Floris van Gaalen7, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Rheumatology Unit, University of Padova, Padova, Italy, 5Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 6Leiden University Medical Center, Leiden, Netherlands, 7Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Imaging of the sacroiliac joints plays a pivotal role in the recognition of axSpA. However, interpretation of imaging is challenging and has led to…
  • Abstract Number: 308 • 2017 ACR/ARHP Annual Meeting

    Frequency, Morbidity and Healthcare Utilization of Diffuse Idiopathic Skeletal Hyperostosis (DISH) Patients at a University Hospital

    Maanas Tripathi1, Divya Rajmohan2, Cody Quirk3, Brooke Beckett3, Donseok Choi4, Neha Rich-Garg5 and Atul A. Deodhar4, 1University of Miami, FL, Miami, FL, 2Oregon Health & Sciences University, Portland, OR, 3Radiology, Oregon Health & Science University, Portland, OR, 4Oregon Health & Science University, Portland, OR, 5Northwest Rheumatology Assoc., Portland, OR

    Background/Purpose: DISH is a non-inflammatory condition affecting the spine, and characterized by ossification of paravertebral ligaments. DISH is traditionally considered asymptomatic, detected incidentally on spine…
  • Abstract Number: 1698 • 2017 ACR/ARHP Annual Meeting

    Quantitative Analyze of Peripheral Vascular Bed in Patients with Systemic Sclerosis By Using Photoacoustic Imaging Technology: A Pilot Study

    Yasuyoshi Kusanagi1, Rika Suzuki1, Dai Murakoshi2, Kazuhiro Hirota2, Kaku Irisawa2, Takatsugu Wada2, Shinpei Okawa3, Miya Ishihara3, Fumihiko Kimura1 and Kenji Itoh1, 1Department of Hematology and Rheumatology, Division of Internal medicine, National Defense Medical College, Saitama, Japan, 2Medical Systems R&D Center, R&D Management Headquarters, Fujifilm Corporation, Kanagawa, Japan, 3Department of Medical Engineering, National Defense Medical College, Saitama, Japan

    Objectives: The aim of this study is to evaluate the usefulness of photoacoustic imaging (PAI) for quantitative analysis of the peripheral vascular bed in patients…
  • Abstract Number: 345 • 2017 ACR/ARHP Annual Meeting

    The Patient Experience of Musculoskeletal Imaging Tests for Investigation of Inflammatory Arthritis: A Mixed Methods Study

    Sandra Bourke1,2, Nicola Dalbeth1, William J. Taylor3, Anthony Doyle1 and Merryn Gott1, 1University of Auckland, Auckland, New Zealand, 2Auckland district health board, Auckland, New Zealand, 3University of Otago, Wellington, New Zealand

    Background/Purpose: Musculoskeletal (MSK) imaging is widely used in rheumatology for diagnosis and management of arthritis. Although the technical and performance properties of MSK imaging tests…
  • Abstract Number: 1845 • 2017 ACR/ARHP Annual Meeting

    Comparison of Magnetic Resonance Angiography (MRA) and 18f-Fluorodeoxyglucose Positron Emission Tomography (PET) in Large Vessel Vasculitis

    Kaitlin A. Quinn1,2, Ashkan Malayeri3, Mark Ahlman3, Armin Bagheri4, Robert Evers5, Ali Cahid Civelek3, Elaine Novakovich6 and Peter C. Grayson7, 1Rheumatology, MedStar Georgetown University Hospital, Washington, DC, 2NIAMS/NIH, Bethesda, MD, 3Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, 4Vasculitis Translational Research Program, NIAMS, NIH, Bethesda, MD, 5NIH, Bethesda, MD, 6Systemic Autoimmunity Branch, NIAMS, National Institutes of Health, Bethesda, MD, 7National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD

    Background/Purpose: Magnetic resonance imaging (MRI) and 18F-fluorodeoxyglucose positron emission tomography (PET) may provide unique or redundant information in large vessel vasculitis (LVV). The study objective…
  • Abstract Number: 567 • 2017 ACR/ARHP Annual Meeting

    Minor Salivary Gland Histopathology, Major Salivary Gland Ultrasonography, and Secretory Function in Smoking Patients with Primary Sjögren’s Syndrome

    Daniel S. Hammenfors1, Haris Causevic2, Johan G. Brun3, Roland Jonsson1 and Malin V. Jonsson4, 1Department of Rheumatology, Haukeland University Hospital, University of Bergen, Bergen, Norway, 2Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, 3Department of Rheumatology, Haukeland University Hospital, Bergen, Bergen, Norway, 4Department of Clinical Dentistry, Section for Oral and Maxillofacial Radiology, University of Bergen, Bergen, Norway

    Background/Purpose: Several studies have reported a protective effect of smoking with regard to risk for primary Sjögren’s syndrome (pSS) and minor salivary gland inflammation. To…
  • Abstract Number: 1878 • 2017 ACR/ARHP Annual Meeting

    The Utility of the Omeract Ultrasound Tenosynovitis Scoring System in Multicenter Clinical Trials

    Mads Ammitzbøll-Danielsen1, Mikkel Østergaard1, Esperanza Naredo2, Annamaria Iagnocco3, Ingrid Moller4, Maria Antonietta D'Agostino5, Frédérique Gandjbakhch6 and Lene Terslev7, 1Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 2Rheumatology, Joint and Bone Research Unit, IIS-FJD, Hospital Universitario Fundación Jiménez Díaz., Madrid, Spain, 3Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy, 4Rheumatology, Instituto Poal, Barcelona, Spain, 5Department of Rheumatology, Assistance publique-Hôpitaux de Paris Ambroise Paré Hospital, Boulogne-Billancourt , Université Versailles Saint Quentin en Yvelines, Paris, France, 6Department of Rheumatology, APHP, Pitié Salpétrière Hospital, Universite Paris 6, Paris, France, 7Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark

    Background/Purpose :Tenosynovitis is very common in patients with RA and is associated with lower physical function.  Several studies have confirmed the limitations of clinical examination…
  • Abstract Number: 582 • 2017 ACR/ARHP Annual Meeting

    Low Dose Computed Tomography Detects More Progression of Bone Formation in Comparison to Conventional Radiography in Patients with Ankylosing Spondylitis

    Anoek de Koning1, Freek de Bruin2, Rosaline van den Berg3, Sofia Ramiro4, Xenofon Baraliakos5, Jürgen Braun5, Floris van Gaalen3, M. Reijnierse6 and Désirée van der Heijde7, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2LUMC, Leiden, Netherlands, 3Rheumatology, LUMC, Leiden, Netherlands, 4Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 5Rheumazentrum Ruhrgebiet, Herne, Germany, 6Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 7Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose : A newly developed scoring method for low dose CT (ldCT) of the whole spine, CT Syndesmophyte Score (CTSS), has shown good inter-reader reliability…
  • Abstract Number: 1984 • 2017 ACR/ARHP Annual Meeting

    The Cervical Spine in Fibromyalgia Patients:  Loss of Lordotic Curve Is Characteristic of Fibromyalgia and Can Assist in the Diagnosis

    Robert S. Katz1, Alexandra Katz Small2, Ben J Small3 and Anthony Farkasch4, 1Rush University Medical Center, Chicago, IL, 2University of Illinois College of Medicine, Chicago, IL, 3Rheumatology, University of Illinois at Chicago Medical School, Chicago, IL, 4Rheumatology Associates S.C., Chicago, IL

    Background/Purpose:  Patients with fibromyalgia have widespread pain. We have found that a lateral view of a cervical spine radiograph frequently identifies a loss of the…
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