Abstracts tagged "Imaging"

Abstract Number: 0703 • ACR Convergence 2021
CD8 Positron Emission Tomography (PET/CT) Imaging with 89Zr-Df-IAB22M2C in Patients with Inclusion Body Myositis
Colin Quinn¹, Kelsey Moulton¹, Ron Korn², William Le³, Niti Goel⁴, Michael Farwell⁵ and Steven Greenberg⁶, ¹Department of Neurology, University of Pennsylvania, Philadelphia, PA, ²ImaginAb, Inglewood, CA, ³ImaginAb, Inc, Inglewood, CA, ⁴Abcuro, Inc., Newton,, MA, ⁵Department of Radiology, University of Pennsylvania, Philadelphia, PA, ⁶Brigham and Women's Hospital Department of Neurology, Boston, MA
Background/Purpose: Inclusion body myositis (IBM) is a slowly progressive autoimmune skeletal muscle disease for which no effective pharmacological therapy is available. A prominent feature of…
Abstract Number: 1474 • ACR Convergence 2021
Automatic Detection of Bone Marrow Lesions from Knee MRI Data from the OAI Study
Shen Liu¹, Xiaoxiao Sun¹, Frank Roemer², Erin Ashbeck³, Edward Bedrick¹, Zong-Ming Li¹, Ali Guermazi⁴ and Kent Kwoh¹, ¹University of Arizona, Tucson, AZ, ²Friedrich-Alexander University Erlangen-Nurnberg, Erlangen, Germany, ³University of Arizona Arthritis Center, Tucson, AZ, ⁴Boston University, Boston, MA
Background/Purpose: Subchondral bone marrow lesions (BMLs) are associated with symptoms and structural progression of knee OA. BMLs are characterized by diffuse hyperintensity on fat suppressed…
Abstract Number: 0168 • ACR Convergence 2021
A Crowdsourcing Approach to Develop Machine Learning Models to Quantify Radiographic Joint Damage in Rheumatoid Arthritis
Dongmei Sun¹, Robert Allaway², Jelai Wang¹, Verena Chung², Thomas Yu², Isaac Dimitrovsky³, Lars Ericson⁴, Yuanfang Guan⁵, Ariel Israel⁶, Hongyang Li⁵, Michael Mason⁷, Alex Olar⁸, Balint Pataki⁸, Stephanie Ledbetter¹, RA2 DREAM Challenge Community⁹, Gustavo Stolovitzky¹⁰, Justin Guinney², Percio Gulko¹¹, Mason Frazier¹, James Costello¹², Jake Chen¹ and S. Louis Bridges, Jr.¹³, ¹University of Alabama at Birmingham, Birmingham, AL, ²Sage Bionetworks, Seattle, WA, ³Self-employed, New York, NY, ⁴Catskills Research, Charlotte, NC, ⁵University of Michigan, Ann Arbor, MI, ⁶Hebrew University, Jerusalem, Israel, ⁷BMS, Seattle, WA, ⁸Eotvos Lorand University, Budapest, Hungary, ⁹RA2 DREAM Challenge Community, New York, NY, ¹⁰IBM, New York, NY, ¹¹Icahn School of Medicine at Mount Sinai, New York, NY, ¹²University of Colorado Anschutz Medical Campus, Denver, CO, ¹³Hospital for Special Surgery, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) is a common chronic autoimmune disease characterized by inflammation of the synovium, leading to joint space narrowing and osseous erosions. The…
Abstract Number: 0772 • ACR Convergence 2021
Pediatric Craniofacial Scleroderma: Assessing Handheld 3D Stereophotogrammetric Imaging Feasibility and Reliability
Daniel Glaser¹, Kaila Schollaert-Fitch², Christopher Liu¹, Jesse Goldstein¹ and Kathryn Torok², ¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Craniofacial scleroderma (Cf-LS), also known as Parry-Romberg Syndrome or scleroderma en coup de sabre, is a subtype of localized scleroderma (morphea). Diagnosis and monitoring…
Abstract Number: 1503 • ACR Convergence 2021
Putting the Pieces on the Board: Mapping SLE Nephritis Biopsies from the Accelerating Medicines Project Using High-Density Immunofluorescence Imaging
Craig Smuda¹, Anna Eichinger², Robert Clancy², Jill Buyon³ and Boris Reizis⁴, ¹NYU Grossman School of Medic ine, New York, NY, ²NYU Grossman School of Medicine, New York, NY, ³NYU School of Medicine, New York, NY, ⁴New York University Grossman School of Medicine, New York, NY
Background/Purpose: The Accelerating Medicines Project (AMP) has enabled significant increases in understanding of SLE nephritis pathology, providing a profile of dozens of leukocyte subsets within…
Abstract Number: 0169 • ACR Convergence 2021
Ultrasonography of Auricular Cartilage Is a Useful Tool for Diagnosing and Monitoring Disease Activity in Relapsing Polychondritis
Yoshinori Taniguchi¹, Hirofumi Nishikawa², Takeshi Yoshida³, Satoshi Inotani⁴ and Yoshio Terada², ¹Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Nankoku, Japan, ²Kochi Medical School Hospital, Nankoku, Japan, ³Chikamori Hospital, Kochi, Japan, ⁴Kochi Medical School Hospital, Kochi-city, Japan
Background/Purpose: In patients with atypical clinical symptoms or imaging findings, because there are no specific and easily measurable markers for RP serologically, it is often…
Abstract Number: 0848 • ACR Convergence 2021
Automatic Hand Segmentation from Hand X-rays Using Minimized Training Samples and Machine Learning Models
Zilong Yang¹, Juan Shan², Carmine Guida², Jordan Blackadar¹, Tino Cheung¹, Jeffrey Driban³, Timothy McAlindon⁴ and Ming Zhang¹, ¹Wentworth Institute of Technology, Boston, MA, ²Pace University, New York, NY, ³Tufts Medical Center, Boston, MA, ⁴Tufts Medical Center, Arlington, MA
Background/Purpose: In many hand osteoarthritis (OA) studies (e.g., automatic Joint Space Width measuring), accurate hand segmentation is the first step towards making further analysis. However,…
Abstract Number: 1574 • ACR Convergence 2021
Comparison of Urate Quantification in Gout and Asymptomatic Hyperuricemia by Ultrasound and Dual Energy Computed Tomography
Rachael Flood¹, Aamir Saeed², Kate Harrington¹, Conor Shortt¹, Ronan Mullan¹ and David Kane¹, ¹Tallaght University Hospital, Dublin, Ireland, ²Worcestershire Acute Hospitals NHS Trust., Worcester, United Kingdom
Background/Purpose: The diagnostic gold standard for gout remains aspiration and identification of monosodium urate (MSU) crystals under polarised light microscopy. Joint aspiration is invasive and…
Abstract Number: 0172 • ACR Convergence 2021
Assessing Relevant Joints for Monitoring CPPD Diseases: A Systematic Literature Review of Imaging Techniques by the OMERACT Ultrasound – CPPD Subgroup
Antonella Adinolfi¹, Silvia Sirotti², Garifallia Sakellariou³, Edoardo Cipolletta⁴, Emilio Filippucci⁵, Francesco Porta⁶, Piercarlo Sarzi-Puttini⁷, Carlo Alberto Scire⁸, Helen Keen⁹, Peter Mandl¹⁰, Carlos Pineda¹¹, Lene Terslev¹², Maria Antonietta D'Agostino¹³, Nemanja Damjanov¹⁴, Annamaria Iagnocco¹⁵ and Georgios Filippou¹⁶, ¹Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milan, Italy, ²Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy, ³Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy, ⁴Rheumatology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy, ⁵Rheumatology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Jesi, Italy, ⁶INS, Institute of Neurosciences, Florence, Italy, ⁷L.Sacco University Hospital, Milano, Italy, ⁸SIR Epidemiology, Research Unit, Pavia, Italy, ⁹University of Western Australia, Daglish, Australia, ¹⁰Medical University of Vienna, Vienna, Austria, ¹¹Instituto Nacional de Rehabilitacion, Mexico City, Federal District, Mexico, ¹²Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen University, Glostrup, Denmark, ¹³Rheumatology, Fondazione Policlinico Universitario “Gemelli”, IRCCS, Rome, Italy, ¹⁴University of Belgrade School of Medicine, Institute of Rheumatology, Belgrade, Serbia, ¹⁵University of Turin, Roma, Italy, ¹⁶Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy
Background/Purpose: Imaging has been extensively used for the diagnosis of Calcium Pyrophosphate Deposition Disease (CPPD) but the exact prevalence of joint calcifications at imaging in…
Abstract Number: 0852 • ACR Convergence 2021
Bone Marrow Lesion Segmentation Using Synthetic Data and Deep Learning Models
Barak Michaely¹, Ming Zhang² and Juan Shan¹, ¹Pace University, New York, NY, ²Wentworth Institute of Technology, Boston, MA
Background/Purpose: Bone marrow lesions (BML) are indicators for knee osteoarthritis (OA) and can be detected from magnetic resonance imaging (MRI). Due to the small size,…
Abstract Number: 1796 • ACR Convergence 2021
Early Identification of Psoriatic Arthritis with Axial Involvement Among Patients with Psoriasis: A Prospective Multicenter Study
Fabian Proft¹, Susanne Lüders², Theresa Hunter³, Gustavo Luna⁴, Valeria Rios Rodriguez¹, Mikhail Protopopov¹, Katharina Meier⁵, Georgios Kokolakis⁵, Kamran Ghoreschi⁵ and Denis Poddubnyy⁶, ¹Charité University Medicine Berlin, Berlin, Germany, ²Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Berlin, Germany, ³Eli Lilly and Company, Indianapolis, IN, USA, Indianapolis, IN, ⁴ICON plc, Stockholm, Sweden, ⁵Department of Dermatology, Venereology and Allergology – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Berlin, Germany, ⁶Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany
Background/Purpose: In the absence of reliable serological and/or imaging biomarkers for early psoriatic arthritis (PsA) and an existing diagnostic delay there is a need for…
Abstract Number: 0514 • ACR Convergence 2020
Feasibility of 18F-fluorodeoxyglucose Positron Emission Tomography to Monitor the Effect of Tocilizumab on Vascular Inflammation in Giant Cell Arteritis: A Prospective Observational Cohort Study
Kaitlin Quinn¹, Himanshu Dashora², Mark Ahlman³, Elaine Novakovich² and Peter C. Grayson², ¹Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, ²Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD, ³National Institutes of Health, Clinical Center, Radiology and Imaging Sciences, Bethesda, MD
Background/Purpose: Two randomized controlled trials have demonstrated the clinical efficacy of tocilizumab for treatment of giant cell arteritis (GCA) (1,2). In these trials, response to…
Abstract Number: 1252 • ACR Convergence 2020
Ultrasound-guided Parotid Gland Biopsy in Cadavers Performed by Rheumatologists – an OMERACT Ultrasound Working Group Study
Nevsun Inanc¹, Sandrine Jousse-Joulin², Kerem Abacar³, Leyla Cinel⁴, Maria D’Agostino⁵, Esperanza Naredo⁶, Alojzija Hocevar⁷, Stephanie Finzel⁸, Lene Terslev⁹, Annamaria Iagnocco¹⁰, Petra Hanova¹¹, Wolfgang Schmidt¹², Gonca Mumcu¹³, Ümit S. Şehirli¹⁴ and George A. Bruyn¹⁵, ¹Marmara University, School of Medicine, Division of Rheumatology, istanbul, Turkey, ²Rheumatology Department, Cavale Blanche Hospital and Brest Occidentale University, Brest, France, ³Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey, ⁴Marmara University, School of Medicine, Division of Pathology, Istanbul, Turkey, ⁵Université Versailles Saint Quentin, Ambroise Paré Hospital, Paris, France, ⁶Department of Rheumatology, Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz, IIS Fundación Jiménez Díaz and Universidad Autónoma de Madrid, Madrid, Spain, ⁷University Medical Center, Rheumatology, Ljubljana, LJUBLJANA, Slovenia, ⁸Universitätsklinikum Freiburg, Klinik für Rheumatologie und Klinische Immunologie, Freiburg, Germany, ⁹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup., Copenhagen, Denmark, ¹⁰Università degli Studi di Torino, Academic Rheumatology Centre, Turin, Italy, ¹¹Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, ¹²Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch, Berlin, Germany, ¹³Marmara University School of Health Sciences, Health Management, Istanbul, Istanbul, Turkey, ¹⁴Marmara University, School of Medicine, Anatomy, Istanbul, Turkey, ¹⁵Rheumatology, Reumakliniek Lelystad, Lelystad, Netherlands
Background/Purpose: With the diagnostic capability of the parotid gland biopsy similar to minor salivary gland biopsy in Sjögren’s syndrome, the parotid gland biopsy may also…
Abstract Number: 1551 • ACR Convergence 2020
Rapid Effect of Tofacitinib in Reducing US Joint and Tendon Inflammatory Lesions of RA Patients: Data from a 24 Weeks Longitudinal Study
Giuseppe Germanò¹, Pierluigi Macchioni², Giovanni Ciancio³, Filippo Crescentini¹, Andrea Caruso², Beatrice Maranini⁴, Sara Bonazza⁴, Gilda Sandri⁵, Maria Teresa Mascia⁵, Govoni Marcello⁴ and Carlo Salvarani⁶, ¹Azienda USL-IRCCS di Reggio Emilia e Università di Modena e Reggio Emilia, REGGIO NELL'EMILIA, Emilia-Romagna, Italy, ²Azienda USL-IRCCS di Reggio Emilia e Università di Modena e Reggio Emilia, REGGIO NELL'EMILIA, Italy, ³Unità Operativa Complessa di Reumatologia Azienda Ospedaliero-Universitaria S. Anna -Ferrara, Ferrara, Emilia-Romagna, Italy, ⁴Unità Operativa Complessa di Reumatologia Azienda Ospedaliero-Universitaria S. Anna -Ferrara, Ferrara, Italy, ⁵Struttura Complessa di Reumatologia- Università di Modena e Reggio Emilia- Policlinico di Modena, Modena, Italy, ⁶Azienda USL-IRCCS di Reggio Emilia e Università di Modena e Reggio Emilia, Reggio Emilia, Italy
Background/Purpose: To explore the effects of tofacitinib (Tofa) on US lesions in a consecutive series of patients with active RA MTX and/or bioDMARDs -IR. Methods: In…
Abstract Number: 2021 • ACR Convergence 2020
The Reliability of Scoring Sonographic Entheseal Abnormalities – the Diagnostic Ultrasound Enthesitis Tool (DUET) Study
Lihi Eder¹, Sibel Aydin² and Gurjit Kaeley³, ¹Women’s College Research Institute, University of Toronto, Toronto, ON, Canada, ²University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA; The Ottawa Hospital Research Institute, Ottawa, ON, CANADA, Ottawa, ON, Canada, ³University of Florida College of Medicine - Jacksonville, Jacksonville, FL
Background/Purpose: DUET is a study supported by the Group for Assessment for Psoriasis and Psoriatic Arthritis (GRAPPA) that aims to develop a novel sonographic scoring…

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