Abstracts tagged "Imaging"

Abstract Number: 865 • 2018 ACR/ARHP Annual Meeting
Structural and Microstructural Intraarticular Bone Changes at the Metacarpal Heads in Patients with Psoriatic Arthritis Compared to Controls: A HR-pQCT Study
Dongze Wu¹, James F Griffith², Steven H.M. Lam¹, Jiang Yue¹, Priscilla Wong¹, Lin Shi³, Edmund Li¹, Isaac T. Cheng¹, Tena K. Li¹, Tracy Y. Zhu⁴, Vivian W. Hung⁴, Ling Qin⁵ and Lai-Shan Tam⁶, ¹Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, Hong Kong, China, ²Department of Imaging and Interventional Radiology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, ³Research Centre for Medical Image Computing, Department of Imaging and Interventional Radiology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, ⁴Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, ⁵Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ⁶Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Metacarpal head directly exposed to intra-articular inflammatory milieu, therefore may lead to abnormal bone remodeling (bone loss and new bone formation). The aims of…
Abstract Number: 866 • 2018 ACR/ARHP Annual Meeting
Patterns of Monosodium Urate Deposition on Dual-Energy CT in Gout Patients on Urate-Lowering Therapy
Chio Yokose¹, Yuqing Zhang², Nicola Dalbeth³, Jie Wei¹, Savvas Nicolaou⁴, Scott Baumgartner⁵, Jia Hu⁶, Maple Fung⁵ and Hyon K. Choi¹, ¹Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ²Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ³University of Auckland, Auckland, New Zealand, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Formerly Ardea Biosciences, San Diego, CA, ⁶Heron Therapeutics, San Diego, CA
Background/Purpose: Gout is typically characterized as an acute monoarthritis involving the joints of the foot. However, polyarticular involvement develops, especially in advanced disease. Patterns of…
Abstract Number: 896 • 2018 ACR/ARHP Annual Meeting
Pharmacogenomics Study of Predicting Response of TNF Blocker and Medical Image Progression in Chinese Han Ankylosing Spondylitis Population
Jing Liu¹, Weilin Pu¹, Qi Zhu², He Fan¹, Wei Wan³, Hejian Zou⁴, Xiaodong Zhou⁵, John D. Reveille⁶, Dongyi He² and Jiucun Wang¹, ¹State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China, ²Institute of Arthritis Research, Shanghai Academy of Chinese Medical Sciences, Guanghua Integrative Medicine Hospital, Shanghai, China, ³Division of Rheumatology, Changhai Hospital, Shanghai, China, ⁴Division of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China, ⁵Internal Medicine-Rheumatology, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, ⁶McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX
Background/Purpose: TNF blockers, have been widely used in immune-mediated diseases and many genetic variations predicting treatment response have been described. We applied previously published genetic…
Abstract Number: 922 • 2018 ACR/ARHP Annual Meeting
Anakinra Treatment Prevents Myocardial Mechanical Dysfunction and Inhibits Histologic Evidence of Myocardial Inflammation in the Mouse Model of Kawasaki Disease
Mark Gorelik^1,2, Youngho Lee³, Masanori Abe⁴, Thomas Andrews⁵, Jean Patterson¹, Magali Noval Rivas⁴, Gregory Aune⁵ and Moshe Arditi⁴, ¹Immunology and Virology, Texas Biomedical Research Institute, San Antonio, TX, ²Pediatrics, Baylor College of Medicine, Houston, TX, ³Department of Cell Biology, Hospital for Sick Children, Toronto, ON, Canada, ⁴Pediatrics, Cedars Sinai, Beverly Hills, CA, ⁵Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX
Background/Purpose: Kawasaki disease (KD) is an acute, febrile illness of childhood with sequelae of coronary artery aneurysms and cardiac fibrosis, and is the most common…
Abstract Number: 12L • 2017 ACR/ARHP Annual Meeting
Evaluation of Intravenous Injection of Tc 99m Tilmanocept in Static Planar Gamma Emission Imaging and Fused SPECT/CT Imaging for Rheumatoid Arthritis
Arash Kardan¹, Bonnie Abbruzzese², James Sanders², Allison Kissling², David Ralph², Joanna Shuping², Michael Blue², Carley Hartings², Rachael Hershey², Ahmad Ismail², Izabela Gierach², Hannah Bailey², Amelia Spaulding², Matthew Haynam², George Zubal³ and Frederick Cope², ¹Charles F. Kettering Memorial Hospital and Wright State University Boonshoft School of Medicine, Dayton, ND, ²Navidea Biopharmaceuticals, Inc., Dublin, OH, ³Z-Concepts, LLC, East Haven, CT

Background/Purpose: Activated macrophages play a critical role in RA by perpetuating inflammation via TNFα release and participating in the destruction of bone and cartilage. Notably,…
Abstract Number: 243 • 2017 ACR/ARHP Annual Meeting
Tracer Uptake from High Resolution Bone SPECT/CT Is Linked to Response in Rheumatoid Arthritis Patients
Yasser Abdelhafez^1,2, Felipe Godinez³, Kanika Sood⁴, Rosalie Hagge², Ramsey D Badawi², Robert D Boutin², Siba P. Raychaudhuri⁵ and Abhijit Chaudhari⁶, ¹Nuclear Medicine Unit, South Egypt Cancer Institute, Assiut University, Assiut, Egypt, ²Radiology, Faculty of Medicine, University of California Davis, Sacramento, CA, ³Biomedical Engineering Department, King’s College London, London, United Kingdom, ⁴Rheumatology Section, Sacramento Veterans Affairs Medical Center, Sacramento, CA, ⁵Rheumatology, VA Sacramento Medical CenterUC Davis School of Medicine, Mather, CA, ⁶Radiology, UC Davis School of Medicine, Sacramento, CA
Tracer Uptake from High Resolution Bone SPECT/CT is Linked to Response in Rheumatoid Arthritis Patients.Background/Purpose: To evaluate the association between response to TNF-_ blockers and…
Abstract Number: 779 • 2017 ACR/ARHP Annual Meeting
Assessment of Treatment Response By 18f-Fludeoxyglucose Positron Emission Tomography (FDG-PET) in Patients with Large Vessel Vasculitis (LVV)
Shubhasree Banerjee¹, Sara Alehashemi², Ali Cahid Civelek³, Elaine Novakovich⁴, Armin Bagheri⁵, Ashkan Malayeri³, Mark Ahlman³ and Peter C. Grayson⁶, ¹Fellowship and training branch, NIAMS/NIH, Bethesda, MD, ²Rheumatology, National Institutes of Health, Bethesda, MD, ³Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁴Systemic Autoimmunity Branch, NIAMS, National Institutes of Health, Bethesda, MD, ⁵Vasculitis Translational Research Program, NIAMS, NIH, Bethesda, MD, ⁶Research, National Institutes of Health, Bethesda, MD
Background/Purpose: Disease activity in large vessel vasculitis (LVV) is traditionally assessed by clinical and serological (ESR, CRP) parameters. Imaging assessment, including FDG-PET, may also be…
Abstract Number: 2020 • 2017 ACR/ARHP Annual Meeting
Definition and Standardization of Inflammatory Pathology in Hand Osteoarthritis Assessed By Ultrasound: Results from a Delphi Process and Reliability Testing in the Omeract Ultrasonographer Group in Hand Osteoarthritis
Alexander Mathiessen¹, Hilde B Hammer¹, Lene Terslev², George A. W. Bruyn³, Maria Antonietta D'Agostino⁴, Georgios Filippou⁵, Emilio Filippucci⁶, Ida Kristin Haugen⁷, Marion Kortekaas⁸, Luana Mancarella⁹, Peter Mandl¹⁰, Ingrid Moller¹¹, Mohamed Atia Mortada¹², Esperanza Naredo¹³, Andrea Delle Sedie¹⁴, Ruth Wittoek¹⁵, Annamaria Iagnocco¹⁶ and Karen Ellegaard¹⁷, ¹Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ³Rheumatology, MC Groep, Loenga, Netherlands, ⁴Department of Rheumatology, Assistance publique-Hôpitaux de Paris Ambroise Paré Hospital, Boulogne-Billancourt , Université Versailles Saint Quentin en Yvelines, Paris, France, ⁵University of Siena, Siena, Italy, ⁶Rheumatology Unit, Università Politecnica delle Marche, Jesi, Italy, ⁷Diakonhjemmet Hospital, Oslo, Norway, ⁸Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁹Rheumatology Unit, Rizzoli Orthopaedic Institute, Bologna, Italy, ¹⁰Department of Internal Medicine III; Division of Rheumatology, Medical University Vienna, Vienna, Austria, ¹¹Instituto Poal de Reumatologia, Barcelona, Spain, ¹²Dept. of Rheumatology, Zagazig University, Zagazig, Egypt, ¹³Rheumatology Department, Hospital Gregorio Marañón, Madrid, Spain, ¹⁴University of Pisa, Rheumatology Unit, Pisa, Italy, ¹⁵Rheumatology, Ghent University Hospital, Ghent, Belgium, ¹⁶Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy, ¹⁷Dept. of Rheumatology, The Parker Institute, Copenhagen, Denmark
Background/Purpose: The introduction of MRI and ultrasound (US) atlases has improved reliability in rheumatoid arthritis. With an increased interest in the role of inflammation in…
Abstract Number: 244 • 2017 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Imaging on PET-CT Using a Novel Folate Receptor Ligand for Macrophage Targeting
Nicki Verweij¹, Stefan Bruijnen¹, Yoony Gent², Marc Huisman³, Gerrit Jansen², Carla Molthoff⁴, Qingshou Chen⁵, Philip Low⁵, Albert Windhorst³, Adriaan Lammertsma³, Otto Hoekstra³, Alexandre Voskuyl² and Conny van der Laken², ¹Dept. of Rheumatology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ²Department of Rheumatology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ³Department of Radiology & Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ⁴Department of Radiology & Nuclear Medicine, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ⁵Department of Chemistry, Purdue University, West Lafayette, IN, USA, West Lafayette, IN
Background/Purpose: PET imaging with macrophage tracers has been shown promising for detection of (sub)clinical synovitis, making it useful for both early diagnostics and therapy monitoring…
Abstract Number: 785 • 2017 ACR/ARHP Annual Meeting
Longitudinal Angiographic Findings in Patients with Takayasu’s Arteritis
Antoine G. Sreih¹, Tanaz A. Kermani², David Cuthbertson³, Simon Carette⁴, Lindsy J. Forbess⁵, Nader A. Khalidi⁶, Curry L. Koening⁷, Carol A. McAlear⁸, Paul A. Monach⁹, Larry W. Moreland¹⁰, Christian Pagnoux¹¹, Philip Seo¹², Robert F. Spiera¹³, Kenneth J. Warrington¹⁴, Steven R. Ytterberg¹⁴, Carol A. Langford¹⁵ and Peter A. Merkel^16,17, ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Division of Rheumatology, University of California, Los Angeles, CA, ³Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, ⁴Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁵Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁶Rheumatology, McMaster University, Hamilton, ON, Canada, ⁷Rheumatology, University of Utah, Salt Lake City, UT, ⁸University of Pennsylvania, Philadelphia, PA, ⁹Boston University School of Medicine, Boston, MA, ¹⁰Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹¹Rheumatology-Vasculitis clinic, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹²Medicine, Johns Hopkins University, Baltimore, MD, ¹³Rheumatology, Hospital for Special Surgery, New York, NY, ¹⁴Rheumatology, Mayo Clinic, Rochester, MN, ¹⁵Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ¹⁶Biostatistics, Epidemiology, and Bioinformatics, University of Pennsylvania, Philadelphia, PA, ¹⁷Division of Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose : Longitudinal data on the type, progression, and predictors of arterial lesions in patients with Takayasu’s arteritis (TAK) is limited. This study aimed to…
Abstract Number: 2057 • 2017 ACR/ARHP Annual Meeting
Identification of Urate Deposits in Patients with Asymptomatic Hyperuricemia Using a Dual-Energy CT Scan
Penny Wang¹, Stacy Smith², Rajesh Garg³, Fengxin Lu¹, Alyssa Wohlfahrt¹, Anarosa Campos¹, Kathleen Vanni⁴, Zhi Yu⁵, Daniel H. Solomon¹ and Seoyoung C. Kim¹, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Radiology, Division of Musculoskeletal Imaging and Intervention, Brigham and Women's Hospital, Boston, MA, ³Division of Endocrinology, Diabetes & Hypertension, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Serum uric acid (sUA) is a useful indicator of the risk of developing gout. However, most patients with elevated sUA levels do not have…
Abstract Number: 246 • 2017 ACR/ARHP Annual Meeting
Development and Validation of a Flourescence Optical Imaging Rheumatoid Arthritis Scoring System for Synovitis in the Wrist and Hand
Mads Ammitzbøll-Danielsen¹, Mikkel Østergaard^1,2, Lene Terslev³, Sarah Ohrndorf⁴ and Daniel Glinatsi¹, ¹Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ²Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, ⁴Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany
Background/Purpose : To assess the intra- and inter-reader agreement and responsiveness of a novel scoring system for FOI-assessed synovitis. Methods: FOI of were obtained of…
Abstract Number: 809 • 2017 ACR/ARHP Annual Meeting
Prevalence and Distribution of Vascular FDG Uptake on Positron Emission Tomography (PET)-CT in Patients Suspected of Having Giant Cell Arteritis – Interim Results from the Giant Cell Arteritis and PET Scan (GAPS) Study
Anthony Sammel¹, Edward Hsiao², Katherine Nguyen³, Geoffrey Schembri², Leslie Schrieber³, Peter Youssef⁴, Beatrice Janssen³ and Rodger Laurent³, ¹Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia, ²Royal North Shore Hospital, St Leonards, Australia, ³Royal North Shore Hospital, St Leonards, Sydney, Australia, ⁴Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
Background/Purpose: Positron emission tomography (PET)-CT scan can assess large vessel vasculitis in giant cell arteritis (GCA). It has a reported sensitivity of 80% for biopsy…
Abstract Number: 2205 • 2017 ACR/ARHP Annual Meeting
Trajectories of Knee Bone Shape Change Are Associated with Sex and Osteoarthritis
Barton L Wise¹, Jingbo Niu², Yuqing Zhang³, Felix Liu⁴, Joyce Pang⁵, John A. Lynch⁶ and Nancy E. Lane⁷, ¹Orthopaedics, Internal Medicine, University of California, Davis School of Medicine, Sacramento, CA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³School Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁵University of Nevada, Reno, Reno, NV, ⁶Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁷Center for Musculoskeletal Health, University of California, Davis School of Medicine, Sacramento, CA
Background/Purpose: Knee osteoarthritis (OA) is more common in women than men; however, the biological mechanisms for sex difference in knee OA are not well understood.…
Abstract Number: 256 • 2017 ACR/ARHP Annual Meeting
Tracking Digital Ulcers in Systemic Sclerosis: Feasibility Study Assessing Lesion Area from Patient-Recorded Smartphone Photographs
Graham Dinsdale¹, Tonia Moore², Joanne Manning², Andrea Murray¹, Ross Atkinson³, Karen Ousey⁴, Mark Dickinson⁵, Christopher Taylor⁶ and Ariane L. Herrick^1,7, ¹Division of Musculoskeletal & Dermatological Sciences, University of Manchester, Salford Royal Hospital NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK, Manchester, United Kingdom, ²Salford Royal Hospital NHS Foundation Trust, Salford, UK, Salford, United Kingdom, ³School of Health Sciences, Division of Nursing, Midwifery & Social Work, University of Manchester, Manchester, UK, Manchester, United Kingdom, ⁴Division of Podiatry and Clinical Sciences, University of Huddersfield, Huddersfield, UK, Huddersfield, United Kingdom, ⁵Photon Science Institute, School of Physics and Astronomy, University of Manchester, Manchester, UK, Manchester, United Kingdom, ⁶Centre for Imaging Sciences, Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK, Manchester, United Kingdom, ⁷NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK, Manchester, United Kingdom
Background/Purpose: Approximately 50% of patients with systemic sclerosis (SSc) will develop painful digital (finger) ulcers (DUs) at some point during their disease course. These lesions…

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