Abstracts tagged "Epidemiology"

Abstract Number: 1670 • ACR Convergence 2021
Increased Prevalence of Gastroesophageal Disease Among Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis
Patompong Ungprasert¹, Nipith Charoenngam², Ben Ponvilawan³, Pitchaporn Yingchoncharoen³ and Jerapas Thongpiya⁴, ¹Cleveland Clinic, Cleveland Heights, OH, ²Mount Auburn Hospital, Boston, MA, ³Mahidol University, Bangkok, Thailand, ⁴Mahdiol University, Bangkok, Thailand
Background/Purpose: Recent experimental studies have suggested that systemic inflammatory response could lead to impairment of lower esophageal function, resulting in gastroesophageal reflux disease (GERD). Epidemiologic…
Abstract Number: 0116 • ACR Convergence 2021
COVID-19 mRNA Vaccine Side Effects Among Individuals with Rheumatic Disease
Kaleb Michaud¹, Adam Cornish², Alison Freifeld¹, Patricia Katz³ and Kristin Wipfler², ¹University of Nebraska Medical Center, Omaha, NE, ²FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, ³University of California San Francisco, San Francisco, CA
Background/Purpose: Over 135 million Americans were fully vaccinated to COVID-19 by June 2021, yet there was a paucity of data on side effects for those…
Abstract Number: 0479 • ACR Convergence 2021
A Novel Semi-automated Classifier of Radiographic Hip Osteoarthritis on DXA Scans Is Strongly Predictive of Pain, Clinical Diagnosis and Joint Replacement: Findings from 40,000 Participants in UK Biobank
Benjamin Faber¹, Raja Ebsim², Fiona Saunders³, Monika Frysz¹, Claudia Lindner², Jennifer Gregory³, Richard Aspden³, Nicholas Harvey⁴, George Davey Smith¹, Timothy Cootes² and Jon Tobias¹, ¹University of Bristol, Bristol, United Kingdom, ²University of Manchester, Manchester, United Kingdom, ³University of Aberdeen, Aberdeen, United Kingdom, ⁴University of Southampton, Southampton, United Kingdom
Background/Purpose: Radiographic hip osteoarthritis (rHOA) is traditionally defined on hip or pelvic radiographs, using subjective methods such as Kellgren-Lawrence scoring. Associations between subjective rHOA measures…
Abstract Number: 0588 • ACR Convergence 2021
Effectiveness of TNFi versus Non-TNFi Biologics on Disease Activity in Obese Patients with Rheumatoid Arthritis: Data from the ACR’s RISE Registry
Milena Gianfrancesco¹, Jing Li¹, Clairissa Ja², Andrea Seet¹, Gabriela Schmajuk¹ and Jinoos Yazdany¹, ¹University of California San Francisco, San Francisco, CA, ²UC Davis, San Francisco
Background/Purpose: Our understanding of how medications such as biologic disease modifying anti-rheumatic drugs and targeted small molecules (b/tsDMARDs) influence disease activity in RA is based…
Abstract Number: 0976 • ACR Convergence 2021
Cumulative Social Disadvantage Predicts an Arthritis Diagnosis: A Cross-sectional Analysis of the National Survey of Children’s Health (NSCH)
William Soulsby, Erica Lawson and Matthew Pantell, University of California San Francisco, San Francisco, CA
Background/Purpose: The impact of social determinants of health in juvenile idiopathic arthritis (JIA) remains poorly understood. Racial disparities exist in JIA, including increased pain and…
Abstract Number: 1121 • ACR Convergence 2021
Association of Healthcare Costs and Utilization with Increasing Severity of Pain in Osteoarthritis Patients: An 18-Year Retrospective Study
Jove Graham¹, Tonia Novosat¹, Haiyan Sun¹, Brian Piper¹, Joseph Boscarino¹, Melissa Kern¹, Vanessa Duboski¹, Eric Wright¹, Craig Beck², Rebecca Robinson³, Edward Casey⁴, Jerry A. Hall³ and Patricia Schepman⁴, ¹Geisinger, Danville, PA, ²Pfizer, Inc., London, ³Eli Lilly and Company, Indianapolis, IN, ⁴Pfizer, Inc., New York, NY
Background/Purpose: Osteoarthritis (OA) is a disease with complex pathogenesis, and it is important to understand a patient's level of severity in order to plan and…
Abstract Number: 1712 • ACR Convergence 2021
Adverse Outcomes and Rehospitalization After Delivery Among Women with Systemic Lupus Erythematosus or Rheumatoid Arthritis and Their Infants
Julianna Sabo¹, Namrata Singh², Deborah Crane¹, David Doody³, Melissa Schiff⁴ and Beth Mueller⁵, ¹University of Washington, Seattle, WA, ²University of Washington, Bellevue, WA, ³Fred Hutchinson Cancer Research Center, Seattle, WA, ⁴University of Washington, University of New Mexico, Seattle, WA, ⁵Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA
Background/Purpose: Women with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) have greater risk of adverse obstetric and birth outcomes than women without these conditions.…
Abstract Number: 0132 • ACR Convergence 2021
Hospitalization Rates Among Patients with Systemic Lupus Erythematosus: A Population Based Study
Jesse Dabit¹, Mehmet Hocaoglu², Maria Valenzuela-Almada³, Shirley-Ann Osei-Onomah¹, Sebastian Vallejo-Ramos¹, Rachel Giblon¹, Kurt Greenlund⁴, Kamil Barbour⁴, Cynthia Crowson⁵ and Ali Duarte-Garcia¹, ¹Mayo Clinic, Rochester, MN, ²University of Maryland Medical Center, Midtown Campus, Baltimore, MD, ³Division of Rheumatology, Mayo Clinic, Rochester, MN, ⁴Centers for Disease Control, Atlanta, GA, ⁵Mayo Clinic, Eyota, MN
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune multiorgan disease associated with significant morbidity and mortality. Although the survival rate for SLE patients has…
Abstract Number: 0480 • ACR Convergence 2021
Signs of Regression to the Mean in Observational Data from a Nation-Wide Exercise and Education Intervention for Osteoarthritis
Martin Englund¹, Dorte Grønne², Ewa Roos², Søren Skou² and Aleksandra Turkiewicz¹, ¹Lund University, Lund, Sweden, ²University of Southern Denmark, Odense, Denmark
Background/Purpose: Patients who enroll in interventions are likely to do so when they experience a flare-up in symptoms. This may create issues in interpretation of…
Abstract Number: 0589 • ACR Convergence 2021
Circulating Adipokines and Risk of Rheumatoid Arthritis in Women
Zhe Fang¹, Jing Cui², Jeffrey Sparks¹, Susan Malspeis², Kazuki Yoshida¹, Karen Costenbader³, Elizabeth Karlson¹ and Bing Lu⁴, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham Women's Hospital, Boston, MA, ³Brigham and Women's Hospital, Belmont, MA, ⁴Brigham and Women's Hospital and Harvard Medical School, Newton, MA
Background/Purpose: Adipokines secreted by adipose tissues thought to be involved in RA pathogenesis by stimulating systematic inflammation. We examined the association between circulating adipokines (leptin,…
Abstract Number: 0989 • ACR Convergence 2021
Risk Factors for Hydroxychloroquine Retinopathy and Its Subtypes – Prospective Adjudication Analysis of 4,899 Incident Users
April Jorge¹, Ronald Melles², Carol Conell³, Na Lu⁴, Michael Marmor⁵, Lucy Young⁶, Natalie McCormick¹, Yuqing Zhang⁷ and Hyon K. Choi⁸, ¹Massachusetts General Hospital, Boston, MA, ²Redwood City Medical Center, Department of Ophthalmology, Kaiser Permanente Northern California, Redwood City, CA, ³Kaiser Permanente Northern California, Palo Alto, CA, ⁴Arthritis Research Canada, Vancouver, BC, Canada, ⁵Stanford University, Palo Alto, CA, ⁶Massachusetts Eye and Ear Institute, Harvard Medical School, Boston, MA, ⁷Division of Rheumatology, Allergy, and Immunology, Mass General Hospital, Harvard Medical School, Boston, MA, ⁸Massachusetts General Hospital, Lexington, MA
Background/Purpose: Hydroxychloroquine (HCQ) is a key treatment for patients with lupus and other rheumatic diseases; however, the known risk factors for HCQ retinopathy (its major…
Abstract Number: 1134 • ACR Convergence 2021
Osteoarthritis Risk Is Increased in Patients with Atopic Disease
Matthew Baker¹, Khushboo Sheth², Rong Lu³, Di Lu³, Ericka von Kaeppler⁴, Archana Bhat⁴, David Felson⁵ and William Robinson⁴, ¹Stanford University, Menlo Park, CA, ²Stanford University/VA Palo Alto, Atherton, CA, ³Stanford University, Stanford, ⁴Stanford University, Palo Alto, CA, ⁵Boston University, Boston, MA
Background/Purpose: Osteoarthritis (OA) is a highly prevalent disease resulting in joint pain and impaired function. Allergic pathways, including mast cell activation, may play a key…
Abstract Number: 1730 • ACR Convergence 2021
Disease Activity and Outcome in Pregnancies of Patients with SpA – Data from the German Pregnancy Register RHEKISS
Anja Weiß¹, Christina Bungartz¹, Jutta Richter², Susanna Späthling-Mestekemper³, Xenofon Baraliakos⁴, Peer Aries⁵, Rebecca Fischer-Betz⁶ and Anja Strangfeld⁷, ¹DRFZ, Berlin, Germany, ²Rheumatology and Hiller Research Unit, Heinrich-Heine-University Duesseldorf, Medical Faculty, Duesseldorf, Germany, ³Rheumapraxis München, München, Germany, ⁴Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ⁵Rheumatologie in Hamburg, Hamburg, Germany, ⁶Uniklinik Dsseldorf, Dsseldorf, Germany, ⁷Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany
Background/Purpose: SpA is a severe chronic inflammatory disease, which affects quality of life and functional status. It frequently occurs in women of childbearing age. Active…
Abstract Number: 0257 • ACR Convergence 2021
Can We Assess Disability in Juvenile Idiopathic Arthritis with Two Simple Questions? Results from the CAPRI Registry
Meghan McPherson¹, Kristin Houghton², Nikola Surjanovic³, Thomas Loughin³, Roberta Berard⁴, Jean-Philippe Proulx-Gauthier⁵, Gaelle Chedeville⁶, Dax Rumsey⁷, Heinrike Schmeling⁸, Nadia Luca⁸, Nicole Johnson⁸, Tommy Gerschman², Paivi Miettunen⁸, Evelyn Rozenblyum⁹, Herman Tam¹⁰, Lilliam Lim⁷, Kimberly Morishita², Rosie Scuccimarri¹¹, Johannes Roth¹², Ciaran Duffy¹², Lori Tucker¹³, Brian Feldman¹⁴ and Jaime Guzman¹⁵, ¹University of Manitoba, Winnipeg, MB, Canada, ²University of British Columbia, Vancouver, BC, Canada, ³Simon Fraser University, Burnaby, BC, Canada, ⁴London Health Sciences Centre, London, ON, Canada, ⁵Laval University, Québec City, QC, Canada, ⁶The Montreal Children's Hospital, Montréal, QC, Canada, ⁷University of Alberta, Edmonton, AB, Canada, ⁸University of Calgary, Calgary, AB, Canada, ⁹Temerty School of Medicine and Unity Health, Toronto, ON, Canada, ¹⁰Stollery Children's Hospital, University of Alberta, Edmonton, AB, Canada, ¹¹MgGill University, Montréal, QC, Canada, ¹²University of Ottawa, Ottawa, ON, Canada, ¹³BC Children's Hospital, Vancouver, BC, Canada, ¹⁴The Hospital for Sick Children, Toronto, ON, Canada, ¹⁵University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada
Background/Purpose: To assess if a combination of two questions (Functional Arthritis Screening with Two Questions - FAST index) can detect and roughly estimate the degree…
Abstract Number: 0482 • ACR Convergence 2021
Metformin Use Reduces the Risk of Developing Osteoarthritis: A Propensity Score Matching Study
Khushboo Sheth¹, Di Lu², Rong Lu², William Robinson³ and Matthew Baker⁴, ¹Stanford University/VA Palo Alto, Atherton, CA, ²Stanford University, Stanford, ³Stanford University, Palo Alto, CA, ⁴Stanford University, Menlo Park, CA
Background/Purpose: Preclinical and observational data suggest a protective effect of metformin against developing osteoarthritis (OA).1,2 In this retrospective cohort study, we evaluated the time to…

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