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Abstracts tagged "Epidemiology"

  • Abstract Number: 0171 • ACR Convergence 2026

    Female hormonal exposures and the risk of incident giant cell arteritis and polymyalgia rheumatica: results from the French E3N prospective cohort study.

    François Barde1, Lucas Pacoureau2, Alexis Elbaz3, Raphaele Seror4 and Yann Nguyen5 Affiliations: 1Inserm, CESP, Paris, Ile-de-France, France, 2University hospital Paris Saclay, Le kremlin bicetre, Ile-de-France, France, 3Inserm, CESP, Villejuif, Ile-de-France, France, 4Service d'immuno-Rhumatologie, Hôpital Universitaire Bicêtre, Université Paris-Saclay, Assistance Publique-Hôpitaux de Par, Le Kremlin Bicêtre, France, le kremlin bicetre, Ile-de-France, France, 5Hopital Beaujon AP-HP.Nord, Montmorency, Ile-de-France, France

    Background/Purpose: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are related inflammatory diseases of adults over 50, with a marked female predominance. While few risk…
  • Abstract Number: 0560 • ACR Convergence 2026

    Clinical Characteristics of Patients with Pediatric-Onset Rheumatic Disease-Associated Interstitial Lung Disease at Diagnosis: Results from a Single-center Cohort

    Eileen Rife1, Emily Smitherman2, Melissa Mannion2, Grant Schulert3 and Livie Timmerman4 Affiliations: 1University of Alabama, Birmingham, Birmingham, 2University of Alabama at Birmingham, Birmingham, AL, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4University of Alabama, Birmingham/COA, Birmingham, AL

    Background/Purpose: Pediatric rheumatic disease-associated interstitial lung disease (PRD-ILD) encompasses a heterogeneous group of conditions with high morbidity yet remains profoundly understudied. We aimed to characterize…
  • Abstract Number: 0803 • ACR Convergence 2026

    Aging Arteries, Changing Care Settings: U.S. Giant Cell Arteritis Mortality, 1999-2020

    Ibrahim Chowdhury1 and Amita Bishnoi2 Affiliations: 1Mclaren Macomb, Sterling Heights, MI, 2Henry Ford Health System, Troy, MI

    Background/Purpose: Giant cell arteritis (GCA) is the most common systemic large-vessel vasculitis of older adults, associated with vision loss, vascular complications, and glucocorticoid-related morbidity. National…
  • Abstract Number: 0833 • ACR Convergence 2026

    Trends and Disparities in Mortality Due to Systemic Connective Tissue Disorders with Coexisting Sepsis in the United States: A 26-Year CDC WONDER Analysis

    Atif Hussain Sarwar1, Karan Chaman Lal2, Muzna Khan2, Yamna Ali Khan3, Rajesh Kumar4, Zobia Tabassum5, Muhammad Mahad2 and Adnan Memon2 Affiliations: 1Duke University North Carolina, Durham, NC, 2Liaquat University of Medical & Health Sciences, Jamshoro, Sindh, Pakistan, 3Dow University of Health Sciences, Karachi, Sindh, Pakistan, 4Liaquat University of Medical & Health Sciences, Gambat, Pakistan, 5Jinnah Sindh Medical University, Karachi, Sindh, Pakistan

    Background/Purpose: Systemic connective tissue disorders (SCTDs) predispose patients to a serious infection by means of immune dysregulation, organ involvement, and immunosuppressive therapy. Their coexistence with…
  • Abstract Number: 1578 • ACR Convergence 2026

    The Landscape of Incident Knee Diagnoses in Adults That May Mimic Symptomatic Osteoarthritis at An Early Structural Stage

    Martin Englund and Aleksandra Turkiewicz Affiliations: Lund University, Lund, Sweden

    Background/Purpose: To estimate the frequency and age-distribution of patients presenting with knee complaints being diagnosed with mimicker conditions to knee osteoarthritis (OA) as well as…
  • Abstract Number: 1755 • ACR Convergence 2026

    Infectious Mononucleosis associated with Increased Risk of Systemic Lupus Erythematosus and Rheumatoid Arthritis

    Elisa Saeedzadeh1, Colleen Maxwell2, Charles N. Bernstein3, Carol Hitchon4, Karl Everett5, Ruth Ann Marrie6, Amirah Momen1, Christine Peschken7, Helen Tremlett8 and Dalia L. Rotstein1 Affiliations: 1University of Toronto, Toronto, Canada, 2University of Waterloo, Waterloo, Canada, 3University of Manitoba, Winnipeg, Canada, 4University of Manitoba, Manitoba, Canada, 5ICES, Toronto, Canada, 6Dalhousie University, Halifax, Canada, 7University of Manitoba, Winnipeg, MB, Canada, 8University of British Columbia, Vancouver, Canada

    Background/Purpose: Recent evidence suggests that Epstein-Barr virus (EBV) infection contributes to the development of systemic lupus erythematosus (SLE) through reprogramming of autoreactive B-cells. However, the…
  • Abstract Number: 2137 • ACR Convergence 2026

    Healthcare Resource Use and Economic Burden of ANCA-Associated Vasculitis in the United States

    Niranjan Kathe1, Prasanth Ravipati2, Phuong Pham3, Sam Oh4, Shubhasree Banerjee5, Alana Bozeman6 and Elizabeth Ibiloye7 Affiliations: 1Amgen Inc, San Diego, CA, 2University of Nebraska Medical Center, Omaha, NE, 3Amgen, Sudbury, MA, 4Amgen, South San Francisco, CA, 5Hospital at University of pennsylvania, Philadelphia, PA, 6Amgen Inc., Thousand Oaks, CA, 7Amgen Inc, Thousand Oaks, CA

    Background/Purpose: The ANCA-associated vasculitis (AAV) treatment landscape has evolved considerably in the past decade. We aimed to describe AAV healthcare resource use (HCRU) and economic…
  • Abstract Number: 2448 • ACR Convergence 2026

    Real-World Safety and Retention of Tofacitinib in Elderly versus Non-Elderly Patients With Rheumatoid Arthritis: A Retrospective Cohort Study in Taiwan

    Yao Fan Fang1, Yen Fu CHEN2 and Ping Han Tsai3 Affiliations: 1Chang Gung Memorial Hospital, Linkou., New Taipei City, New Taipei, Taiwan (Republic of China), 2Division of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan, New Taipei, New Taipei, Taiwan (Republic of China), 3Division of Rheumatology, Allergy and Immunology, New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan, New Taipei city, New Taipei, Taiwan (Republic of China)

    Background/Purpose: Tofacitinib, the first approved oral small-molecule Janus kinase inhibitor (JAKi), is widely used for treating rheumatoid arthritis (RA). This study aims to compare the…
  • Abstract Number: 2740 • ACR Convergence 2026

    Comparative Effectiveness of Anti-Diabetic Medications on the Risk of Post-Traumatic Osteoarthritis Outcomes

    Michael LaValley1, David Felson2, S. Reza Jafarzadeh3 and Nene Ukonu3 Affiliations: 1Boston University School of Public Health, Arlington, MA, 2Boston University, Boston, MA, 3Boston University Chobanian & Avedisian School of Medicine, Boston, MA

    Background/Purpose: Post-traumatic osteoarthritis (PTOA) develops following joint injury and accounts for 12 - 20% of all osteoarthritis (OA).  GLP1 agonists (GLP1a) and SGLT2 inhibitors (SGLT2i) are two diabetic medications…
  • Abstract Number: 2768 • ACR Convergence 2026

    Sociodemographic and Clinical Characteristics of Early- and Late-Onset Gout Among U.S. Adults: NHANES 2011-2018

    Sandipa Sharma1, Subash Sapkota2, Andreina Martinez Paulino1, Danny Ariaz Diaz1 and Valentin Marian3 Affiliations: 1Department of Internal Medicine, Rutgers Health/Jersey City Medical Center, Jersey City, NJ, 2Hackensack Meridian Health, Neptune, 3Division of Rheumatology, Rutgers Health/Jersey City Medical Center, BRIDGEWATER, NJ

    Background/Purpose: Although the risk of gout increases with age, around 700,000 patients in the U.S. develop early-onset gout, commonly defined as first gout attack at…
  • Abstract Number: 2927 • ACR Convergence 2026

    Diabetes Risk in Rheumatoid Arthritis Has Not Improved Over the Modern Treatment Era

    Megan Mattison1, Punyasha Roul2, Joshua Baker3, Gary Kunkel4, Grant Cannon5, Ted Mikuls6, Bryant England6 and Tate Johnson6 Affiliations: 1University of Nebraska, Omaha, NE, 2UNMC, Omaha, NE, 3University of Pennsylvania, Philadelphia, PA, 4University of Utah and George E Wahlen VAMC, Salt Lake City, UT, 5University of Utah and Salt Lake City VA, Salt Lake City, UT, 6University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Higher disease activity and cytokine expression are associated with diabetes mellitus (DM) risk in RA (Baker, et al. Ann Rheum Dis 2021), though reports…
  • Abstract Number: 0197 • ACR Convergence 2026

    Development and Validation of a Claims-Based Algorithm for Relapse Detection in Granulomatosis With Polyangiitis and Microscopic Polyangiitis

    Guy Katz1, Naomi Patel1, Andrew King2, Belen Arevalo1, Bohang Jiang3, Madison Negron4, Nora Shepherd5, Ana Fernandes6, Niranjan Kathe7, Alana Bozeman8, Elizabeth Ibiloye9, Sam Oh10, Zachary Wallace11 and Sebastian Unizony12 Affiliations: 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Boston, 3MGH, Boston, MA, 4Harvard Extension School, Medford, MA, 5George Washington University, Boston, MA, 6Medical School Candidate, Boston, MA, 7Amgen Inc, San Diego, CA, 8Amgen Inc., Thousand Oaks, CA, 9Amgen Inc, Thousand Oaks, CA, 10Amgen, South San Francisco, CA, 11Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, 12Massachusetts General Hospital / Harvard Medical School, Winchester, MA

    Background/Purpose: Approximately 50% of patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) relapse within 5 years of diagnosis.1 Relapse contributes to organ damage…
  • Abstract Number: 0582 • ACR Convergence 2026

    Patient & Caregiver Global Score is a Predictor of Risk of JIA Flare: A Retrospective Cohort Study in the CARRA Registry

    Daniel Horton1, Laura Berbert2, Anna Sutton3, Jessica Kent4, Julianne Varga5, Edie Weller6, Timothy Beukelman7, Sarah Ringold8 and Melissa Mannion9 Affiliations: 1Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 2Boston Children's Hospital, Belmont, MA, 3University of Washington, Woodinville, WA, 4Medical College of Wisconsin, Milwaukee, WI, 5Rutgers University, New Brunswick, 6Biostatistics and Research Design Center, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, MA, 7CARRA, Washington, DC, 8Johnson & Johnson, San Diego, 9University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Planned tapering or stopping (i.e., deprescribing) of DMARDs in patients with JIA comes with risks of flare. However, few clinical factors reliably predict flares…
  • Abstract Number: 0806 • ACR Convergence 2026

    Cause-Specific Mortality in Incident Systemic Lupus Erythematosus: A Population-Based Cohort Study

    José A. Gómez-Puerta1, Cristian Tebe2, Beatriz Frade-Sosa3, Juan Camilo Sarmiento-Monroy1, Patricia Corzo3, Cristina Carbonell-Abella4, Daniel Martinez-Laguna5 and J Antonio Aviña-Zubieta6 Affiliations: 1Rheumatology Department, Hospital Clinic de Barcelona, Barcelona, Spain, 2IGTP, Badalona, Spain, 3Rheumatology Department, Hospital Clínic de Barcelona, Barcelona, Spain, 4Medicina Familiar y Comunitaria, Centro de Salud Vía Roma,, Barcelona, Spain, 5CAP Sant Martí, IDIAP, ICS. Barcelona, Barcelona, Spain, 6Division of Rheumatology, Faculty of Medicine, University of British Columbia,, Vancouver, BC, Canada

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease associated with increased morbidity and premature mortality. Although overall survival has improved, important gaps remain…
  • Abstract Number: 0862 • ACR Convergence 2026

    Evidence on the Clinical Validity of the 2023 ACR/EULAR Antiphospholipid Syndrome Criteria in a Longitudinal Lupus Cohort

    Pankti Mehta1, Fadi Kharouf2, Qixuan Li1, Dafna Gladman3, Laura Patricia Whittall Garcia2 and Zahi Touma4 Affiliations: 1University of Toronto, Toronto, ON, Canada, 2University Health Network, Toronto, ON, Canada, 3University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4University of Toronto Lupus Clinic, Division of Rheumatology, Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

    Background/Purpose: The 2006 Sydney classification criteria for Antiphospholipid syndrome (APS) have been widely used but our understanding of APS manifestations has evolved since then. The…
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