Abstracts tagged "Enthesitis"

Abstract Number: 314 • 2018 ACR/ARHP Annual Meeting
Development and Preliminary Validation of an Omeract Magnetic Resonance Imaging (MRI) Scoring System for Ankle Enthesitis in Spondyloarthritis
Ashish J Mathew¹, Simon Krabbe², Iris Eshed³, Frédérique Gandjbakhch⁴, Robert G. Lambert⁵, Paul Bird⁶, Kay-Geert Hermann⁷, Susanne J Pedersen⁸, Maria Stoenoiu⁹, Violaine Foltz¹⁰, Walter P. Maksymowych¹¹, Daniel Glinatsi², Ida K Haugen¹², Jacob L. Jaremko¹³, Rene P Poggenborg¹⁴, Joel Paschke¹⁵, Jean Denis Laredo¹⁶, Philip G. Conaghan¹⁷ and Mikkel Østergaard¹⁸, ¹Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India, Vellore, India, ²Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ³Department of Radiology, Sheba Medical Center, Israel, Tel Hashomer, Israel, ⁴Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, Paris, France, Paris, France, ⁵University of Alberta, Edmonton, Canada, Edmonton, AB, Canada, ⁶University of New South Wales, Sydney, Australia, Sydney, Australia, ⁷Radiology, Charité Universitätmeidzin, Berlin, Germany, Berlin, Germany, ⁸Depart of Rheumatology VRR, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ⁹Université catholique de Louvain, Brussels, Belgium, Brussels, Belgium, ¹⁰UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, Paris, France, ¹¹Department of Medicine, CaRE Arthritis and University of Alberta, Edmonton, Canada, Edmonton, AB, Canada, ¹²P.O. Box 23 Vinderen, Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, ¹³Radiology, University of Alberta, Edmonton, Canada, Edmonton, AB, Canada, ¹⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ¹⁵CaRE Arthritis, Edmonton, Canada, Edmonton, AB, Canada, ¹⁶Hôpital Lariboisière, APHP and Université Paris-Diderot, Paris, France, Paris, France, ¹⁷University of Leeds, Leeds, UK, Leeds, United Kingdom, ¹⁸Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Background/Purpose: Enthesitis is a key feature in spondyloarthritis (SpA). MRI allows sensitive visualization of entheseal inflammation and damage, but no validated, internationally accepted MRI scoring…
Abstract Number: 678 • 2018 ACR/ARHP Annual Meeting
Ultrasonographic Evaluation of Achilles Tendon in Early Axial Spondyloarthropathy: Is There Any Difference between Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthropathy?
Shahla Vahidfar¹, Ismihan Sunar², Sebnem Ataman³, Gürkan Yılmaz⁴, Javid M. AZARABADI⁵ and Ayşe Bölükbaşı¹, ¹Physical Medicine and Rehabilitation, Ankara University Faculty of Medicine, Ankara, Turkey, ²Department of Physical Medicine and Rehabilitation, Division of Rheumatology,, Ankara University, Faculty of Medicine, Ankara, Turkey, ³Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Ankara University Faculty of Medicine, Ankara, Turkey, ⁴Physical Medicine and Rehabilitation, Rheumatology Division, Ankara University Faculty of Medicine, Ankara, Turkey, ⁵ORTHOPEDICS AND TRAUMATOLOGY, Başkent University Faculty of Medicine, Ankara, Turkey
Background/Purpose: Along with emergence of the term of ‘non-radiographic axial SpA’ (nr-AxSpA), studies comparing AS and nr-AxSpA in terms of genetic, epidemiologic, and clinical issues…
Abstract Number: 679 • 2018 ACR/ARHP Annual Meeting
Ultrasonographic Research of the Relationship between Nail Disorders and Peripheral Arthritis or Enthesitis in Patients with Psoriasis and Psoriatic Arthritis
Tadashi Okano¹, Kentaro Inui², Koji Mandai³, Yutaro Yamada⁴, Tatsuya Koike⁵ and Hiroaki Nakamura², ¹Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ³Orthopaedic surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ⁴Orthopedic surgery, Yodogawa Christian Hospital, Osaka, Japan, ⁵Center for Senile Degenerative Disorders, Osaka City University Graduate School of Medicine, Osaka, Japan
Background/Purpose: Although skin lesion is the most typical findings in patients with psoriasis (PsO), nail psoriasis is also one of the important clinical manifestation. Moreover,…
Abstract Number: 1028 • 2018 ACR/ARHP Annual Meeting
An Entheseal Innate Immune Cell Biological Basis for Differential Efficacy of PDE4 and IL-23 Pathway Blockade between Psoriatic Disease and Rheumatoid Arthritis
Charlie Bridgewood¹, Richard Cuthbert¹, Abdulla Watad², Tobias Russell¹, Timothy Palmer³, Robert Dunsmuir⁴, Almas Khan⁴, Abhay Rao⁴, Miriam Wittmann⁵ and Dennis McGonagle¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Department of Internal Medicine 'B', Sheba Medical Center, Ramat Gan, Ramat Gan, Israel, ³School of Pharmacy and Medical Sciences, University of Bradford, Bradford, United Kingdom, ⁴Department of Spinal Surgery, National Health Service, Leeds, United Kingdom, ⁵NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: Both IL-23 and phosphodiesterase (PDE) 4 inhibition are ineffective in RA but show efficacy in PsA-related synovitis despite similar cytokine and molecular profiles between…
Abstract Number: 1207 • 2018 ACR/ARHP Annual Meeting
Clinical Evaluation Correlates Poorly with Ultrasound and Magnetic Resonance Imaging of Joints and Entheses in Early Peripheral Spondyloarthritis
Thomas Renson¹, Ann-Sophie De Craemer¹, Philippe Carron¹, Simon Krabbe², Lennart Jans³, Manouk de Hooge⁴, Peggy Jacques¹, Mikkel Østergaard⁵, Dirk Elewaut¹ and Filip van Den Bosch⁶, ¹Department of Rheumatology, Ghent University Hospital, Ghent, 9000, Belgium, ²Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ³Department of Radiology, Ghent University Hospital, Ghent, Belgium, ⁴Ghent University Hospital, Ghent, Belgium, ⁵Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Copenhagen, Denmark, ⁶Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
Background/Purpose: Enthesitis is a hallmark of spondyloarthritis (SpA), which occurs in 30 to 50% of psoriatic arthritis patients [1]. Evaluation of tenderness at the site…
Abstract Number: 1591 • 2018 ACR/ARHP Annual Meeting
Is Enthesitis a Marker of Disease Severity in Early Psoriatic Arthritis?
Lihi Eder¹, Chandra Farrer² and Dana Jerome³, ¹Women's College Research Institute, University of Toronto, Women's College Hospital, Toronto, ON, Canada, ²Rheumatology, Women's College Hospital, Toronto, ON, Canada, ³University of Toronto, Women's College Hospital, Toronto, ON, Canada
Background/Purpose: Enthesitis is a key feature in psoriatic arthritis (PsA) affecting approximately a third of the patients. Ultrasound improves the detection of enthesitis compared to…
Abstract Number: 1602 • 2018 ACR/ARHP Annual Meeting
Disease Characteristics, Quality of Life, and Work Productivity By Enthesitis Sites: Real-World Data from the US Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry
Philip J. Mease¹, Mei Liu², Sabrina Rebello³, Winnie Hua², Robert R. McLean², Peter Hur⁴ and Alexis Ogdie⁵, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Corrona, LLC, Waltham, MA, ³Corrona, LLC, Southborough, MA, ⁴Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA, East Hanover, NJ, ⁵Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Prior studies showed psoriatic arthritis (PsA) patients with enthesitis had greater disease burden than patients without enthesitis, yet it is unknown whether the impact…
Abstract Number: 1614 • 2018 ACR/ARHP Annual Meeting
Prevalence of Sonographic Enthesitis in Patients with Psoriasis without Arthritis and Its Association Risk Factors of Psoriatic Arthritis
Anwar Albasri¹, Justine Y. Ye², Cheryl F. Rosen³, Vinod Chandran², Dafna D Gladman⁴ and Lihi Eder⁵, ¹Rheumatology, University of Toronto, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Department of Medicine, Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁵Women's College Research Institute, University of Toronto, Women's College Hospital, Toronto, ON, Canada
Background/Purpose: Enthesitis is one of the hallmarks of psoriatic arthritis (PsA) and may be the initial site of musculoskeletal inflammation. Enthesitis affects up to 50…
Abstract Number: 1632 • 2018 ACR/ARHP Annual Meeting
Ultrasonographic Evaluation of the Enthesis in Patients Affected By Entheropatic Spondiloarthritis. Focus on Distal Enthesis of the Patellar Tendon
Alberto Batticciotto¹, Giada Prato², Marco Antivalle³, Maria Chiara Ditto⁴, Michele Agosti⁵, Enrico Cumbo², Rossella Talotta², Fabiola Atzeni⁶ and Piercarlo Sarzi-Puttini⁵, ¹SS Reumatologia Ospedale di Circolo - fondazione Macchi ASST Settelaghi, Varese, Italy, ²Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milan, Italy, ³Rheumatology, Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milano, Italy, ⁴Department of Rheumatology, University Hospital Città Della Salute e della Scienza di Torino, Turin, Italy, ⁵Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milano, Italy, ⁶Department of Clinical and Experimental Medicine, Rheumatology Unit, University of Messina, Messina, Italy
Background/Purpose: Enteropathic arthritis (EA) belongs to the spondyloarthritis (SpA) spectrum of diseases and occurs in patients affected by inflammatory bowel diseases (IBD). Several works demonstrated…
Abstract Number: 1657 • 2018 ACR/ARHP Annual Meeting
The Effect of Guselkumab on Enthesitis: Results from a Phase 2 Study in Patients with Active Psoriatic Arthritis
Philip Helliwell¹, Alice B Gottlieb², Atul A. Deodhar³, Wolf-Henning Boehncke⁴, Dennis McGonagle¹, Xie L. Xu⁵, Stephen Xu⁵, Yuhua Wang⁵, Elizabeth C Hsia^5,6, Chetan S Karyekar⁵ and Philip J. Mease⁷, ¹U of Leeds, Leeds, United Kingdom, ²NY Medical College, Metropolitan Hospital, NY, NY, ³Oregon Health & Science U, Portland, OR, ⁴U of Geneva, Geneva, Switzerland, ⁵Janssen Research & Development, LLC, Spring House, PA, ⁶U Penn School of Medicine, Phila, PA, ⁷Swedish Medical Center & U of Wash, Seattle, WA
Background/Purpose: In a Phase 2 study, Guselkumab (GUS) was shown to be safe & effective in pts w/active PsA w/meaningful improvements in enthesitis. To evaluate…
Abstract Number: 1551 • 2017 ACR/ARHP Annual Meeting
Avoidance of Physical Activity Leads to Reduced Inflammatory Enthesitis on Ultrasound
Kim Wervers¹, Irene Herrings¹, Jolanda J. Luime², Marlies Moed¹, Ilja Tchetverikov³, Andreas H. Gerards⁴, J.M.W. Hazes⁵ and Marijn Vis², ¹Erasmus Medical Centre, Rotterdam, Netherlands, ²Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands, ³Albert Schweitzer Hospital, Dordrecht, Netherlands, ⁴Sint Franciscus Vlietland Group, Schiedam, Netherlands, ⁵Department of Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands
Background/Purpose: Enthesitis is one of the manifestations of psoriatic arthritis (PsA), but no clear definition for the diagnosis exists. To further evaluate the added value…
Abstract Number: 1608 • 2017 ACR/ARHP Annual Meeting
Entheseal Involvement in Systemic Lupus Erythematosus: An Ultrasound Study
Andrea Di Matteo¹, Emilio Filippucci², Edoardo Cipolletta², Valentina Lato², Jana Hurnakova^3,4, Iulia Satulu⁵, Rossella De Angelis² and Walter Grassi², ¹Polytechnic University of Marche, Rheumatology Clinic, Jesi, Italy, ²Polytechnic University of Marche, Rheumatology Clinic, jesi, Italy, ³1st Faculty of Medicine, Institute of Rheumatology and Department of Rheumatology, Prague, Czech Republic, ⁴University Hospital Motol, Department of Pediatric and Adult Rheumatology, Prague, Czech Republic, ⁵Rheumatology Department, Internal Medicine Clinic, Kalmar County Hospital, kalmar, Sweden
Background/Purpose: A recent study revealed ultrasound (US) findings indicative of entheseal involvement in a small group of patients with systemic lupus erytemathosus (SLE), raising the…
Abstract Number: 1874 • 2017 ACR/ARHP Annual Meeting
Development of an Ultrasonographic Enthesitis Score for Psoriatic Arthritis Patients
Stephanie Tom^1,2, Yujie Zhong³, Richard J. Cook⁴, Sibel Z. Aydin^5,6, Gurjit S. Kaeley⁷ and Lihi Eder^8,9, ¹Women's College Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom, ⁴Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ⁵The Ottawa Hospital, Ottawa, ON, Canada, ⁶University of Ottawa, Ottawa, ON, Canada, ⁷University of Florida, Ponte Vedra Beach, FL, ⁸Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada, ⁹Medicine, University of Toronto, Toronto, ON, Canada
Background/Purpose: Enthesitis affects approximately a third of patients with psoriatic arthritis (PsA) and is often considered the earliest site of inflammation. The accuracy of clinical…
Abstract Number: 2311 • 2017 ACR/ARHP Annual Meeting
Prospective Validation of the Juvenile Spondyloarthritis Disease Activity Index and Its Comparison with Adult Spondyloarthritis Disease Activity Scores
Abhishek Zanwar, Sanat Phatak and Amita Aggarwal, Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Background/Purpose: Among JIA children with Enthesitis related arthritis (ERA) category have more pain, poorer health status and are less likely to achieve or maintain sustained…
Abstract Number: 2503 • 2017 ACR/ARHP Annual Meeting
Does Maastricht Ankylosing Spondylitis Enthesitis Scores Differ between Ankylosing Spondylitis, Psoriatic Arthritis and Rheumatoid Arthritis Patients?
Steffan Robstad Nilssen¹, Jintana B: Andersen¹, Hanne K. Vestaby¹, Glenn Haugeberg² and Brigitte Michelsen³, ¹Dept. of Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, ²Martina Hansens Hospital, Bærum, Norway, ³Dept. of Rheumatology, Hospital of Southern Norway Trust, kristiansand, Norway
Background/Purpose: The Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) is an enthesitis index developed and validated as an outcome measure in ankylosing spondylitis (AS), but is…

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