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Abstracts tagged "Behçet’s Syndrome"

  • Abstract Number: 1562 • ACR Convergence 2022

    Validation of Behçet’s Disease Overall Damage Index (BODI) for Retrospective Studies and a Proposal for Modification

    Yeliz Yagiz Ozogul1, Yesim Ozguler2, Didar Ucar3, Ugur Uygunoglu4, Zekayi Kutlubay5, Vedat Hamuryudan6 and gulen Hatemi7, 1Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Internal Medicine, Istanbul, Turkey, 2Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, New York, NY, 3Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Ophthalmology, Istanbul, Turkey, 4Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Neurology, Istanbul, Turkey, 5Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Dermatology, Istanbul, Turkey, 6Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 7Istanbul University-Cerrahpaşa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey

    Background/Purpose: Damage accrual in Behçet syndrome (BS) may progress over the years and an index that can be scored using retrospective data may be useful…
  • Abstract Number: 1881 • ACR Convergence 2021

    Surgical Outcomes After Operative Procedures in Patients with Behcet’s Disease

    Youjin Jung and Eun bong Lee, Seoul National University Hospital, Seoul, Republic of Korea

    Background/Purpose: Behcet's disease (BD) is characterized by hyper-inflammatory response to trauma, which is called the pathergy phenomenon. Therefore, there are concerns about post-operative complications when…
  • Abstract Number: 1883 • ACR Convergence 2021

    Neuro-Behcet’s Disease: 20 Years Single Center Experience of Cyclophosphamide for Induction of Remission

    Pablo Vinicius da Fonseca, Henrique Ayres Mayrink Giardini,, Célio Roberto Gonçalves and Leandro Lara do Prado, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Behçet's disease (BD) is a systemic vasculitis. Neurological involvement, also known as Neuro-Behçet's disease (NBD), leads to great morbimortality. Diagnosis is challenging, since clinical…
  • Abstract Number: 1885 • ACR Convergence 2021

    Biological Therapy in Refractory Neurobehçet’s Disease. Multicenter Study of 42 Patients

    Alba Herrero-Morant1, José Luis Martin-Varillas2, Vanesa Calvo-Río3, Santos Castañeda4, Olga Maíz5, Ana Blanco6, Julio Sánchez7, Norberto Ortego8, Enrique Raya9, Anahy Maria Brandy-Garcia10, Alejandro Olive-Marques11, Agueda Prior-Español12, Clara Moriano13, Elvira Díez14, Rafael Melero15, Jenaro Enrique Grana Gil16, Álvaro Seijas-López17, Ana Urruticoechea-Arana18, Ángel Ramos-Calvo19, Concepcion Delgado-Beltran20, Marta Loredo-Martinez20, Eva Salgado21, Francisca Sivera22, Ignacio Torre23, Javier Narvaez24, Jose Luis Andreu25, Olga Martinez26, Ricardo Gómez de la Torre27, Sabela Fernandez-Aguado28, Susana Romero-Yuste29, Gerard Espinosa30, Miguel Ángel gonzalez-Gay31 and Ricardo Blanco3, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 4Hospital Universitario de la Princesa, Madrid, Spain, 5Hospital Universitario de Donostia, San Sebastián, Spain, 6Hospital Universitario de Donostia, San Sebastián, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Medicine Department, Universidad de Granada, Granada, Spain, 9Hospital San Cecilio, Granada, Spain, 10Hospital Germans Trias i Pujol, Badalona, Spain, 11Rheumatology Service. Hospital Germans Trias i Pujol, Barcelona, Spain, 12Department of Rheumatology, Germans Trias i Pujol. University Hospital, Badalona, Spain, 13Hospital Universitario de León, León, Spain, 14Hospital de León, León, Spain, 15Complexo Hospitalario Universitario de Vigo, Vigo, Galicia, Spain, 16Hospital Universitario de A Coruña, A Corua, Spain, 17Hospital Universitario de A Coruña, A Coruña, Spain, 18H. Can Misses, Elvissa, Spain, 19Complejo Hospitalario de Soria, Soria, Spain, 20Hospital Clínico Lozano Blesa, Zaragoza, Spain, 21Complejo Hospitalario Universitario de Ourense, Ourense, Spain, 22Hospital Universitario de Elda, Alicante, Spain, 23Hospital Universitario de Basurto, Bilbao, Spain, 24Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 25Hospital Universitario Puerta de Hierro, Madrid, Spain, 26H. Salamanca, Zamora, Spain, 27H. Asturias, Oviedo, Spain, 28Hospital Universitario de Cabueñes, Gijón, Spain, 29Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain, 30Hospital Clinic, Barcelona, Spain, 31Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose: Neurobehçet’s disease (NBD) is a severe complication of Behcet's disease (BD). Despite well-established therapies, with glucocorticoids and conventional immunosuppressants (cIS) a significant proportion of…
  • Abstract Number: 1887 • ACR Convergence 2021

    Evidence-Based Behçet’s Disease Activity Scale (EBDA) – A New Instrument with Improved Acuity for Major Organ Disease Activity and Remission Depth Assessment

    Maria Caterina Lagdameo1, Hyungrok Do2 and Johannes Nowatzky1, 1Division of Rheumatology, New York University School of Medicine, New York, NY, 2Department of Population Health, NYU School of Medicine, New York

    Background/Purpose: Most current Behçet’s disease (BD) activity assessment tools are strongly based on patient-reported symptoms and findings allowing a wide range of observer-dependent interpretations and…
  • Abstract Number: 1046 • ACR Convergence 2021

    Risk of Ocular Comorbidities and Blindness Among Patients with Behçet’s Disease: A Nationwide Population-based Cohort Study in Korea

    SE RIM CHOI1, Anna Shin2, Joo Young Shin3, Hokyung Choung3, You-Jung Ha2, Yun Jong Lee4, Eun bong Lee1, Jin Kyun Park1 and Eun Ha Kang2, 1Seoul National University Hospital, Seoul, Republic of Korea, 2Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea, 3Department of Ophthalmology, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea, 4Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea

    Background/Purpose: To examine the risk of ocular comorbidities in a nation-wide cohort of patients with Behçet’s disease (BD) compared to general population in Korea.Methods: We…
  • Abstract Number: 1050 • ACR Convergence 2021

    Epidemiology and Clinical Features of Ophthalmological Manifestations in Behçet’s Disease: Study of 50 Patients of a Series of 120 Patients in a Region in Northern Spain

    Alba Herrero-Morant1, Guillermo Suárez-Amorín1, Rosalia Demetrio-Pablo1, Lara Sánchez-Bilbao1, Carmen Álvarez-Reguera1, David Martinez-Lopez1, Raul Fernandez1, José Luis Martin-Varillas2, Cristina Mata-Arnaiz3, Miguel Ángel gonzalez-Gay4 and Ricardo Blanco5, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Laredo, Santander, Spain, 4Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 5Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Ophthalmological involvement is one of the most feared manifestations of Behçet’s disease.The aim of this study was to define the main demographic and clinical…
  • Abstract Number: 1109 • ACR Convergence 2021

    Comparison of Diagnostic Criteria in Behçet’s Disease and Sensitivity in Diagnosing Severe Manifestations

    Carmen Álvarez-Reguera1, Alba Herrero-Morant1, Lara Sánchez-Bilbao1, David Martinez-Lopez1, José Luis Martin-Varillas2, Guillermo Suárez-Amorin1, Maria Cristina Mata-Arnaiz3, Miguel Ángel gonzalez-Gay4 and Ricardo Blanco5, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital de Laredo, Spain, Spain, 4Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 5Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Behçet disease (BD) is characterized by painful recurrent oral aphthosis genital ulcers and skin lesions. Nevertheless, the major causes of morbidity result from ocular,…
  • Abstract Number: 1727 • ACR Convergence 2021

    Behcet’s Disease: A Meta-analysis of Pregnancy Outcomes

    Leah Rooney1, Aine Gorman2, Matthew Turk3, Louise Moore4, Celine O'Brien5, Jared Bierbrier6, Anne Clohessy5, Eamonn Molloy7, Lorraine O Neill8, Fionnuala M. Mc Auliffe5 and Douglas Veale9, 1St Vincent's University Hospital, Dublin, Ireland, 2St Vincents Hospital, Dublin, Ireland, 3St. Vincents University Hospital, Dublin, Ireland, 4Our Lady's Hospice and Care Services, Harold's Cross, Dublin 6W, Kinnegad, Ireland, 5Perinatal Research Centre, Obstetrics and Gynaecology, School of Medicine, University College Dublin and National Maternity Hospital, Dublin, Dublin, Ireland, 6McMaster University, Hamilton, ON, Canada, 7St Vincent's Healthcare Group, Dublin, Ireland, 8St. Vincent's Hospital, Dublin, Ireland, 9University College Dublin, Dublin, Ireland

    Background/Purpose: Behcet’s disease is a systemic inflammatory disease which commonly presents with episodes of acute inflammation, oral and genital ulcers, uveitis and skin lesions. It…
  • Abstract Number: 1863 • ACR Convergence 2021

    Consistent Efficacy with Apremilast in Men and Women to Treat Oral Ulcers Associated with Behçet’s Syndrome: Results from Phase 3 Researching Oral Apremilast Safety and Efficacy in Behçet’s Disease (RELIEF) Study

    Gülen Hatemi1, Alfred Mahr2, Mitsuhiro Takeno3, Doyoung Kim4, Melike Melikoğlu5, Sue Cheng6, Sven Richter6, Shauna Jardon7, Maria Paris6, Mindy Chen6 and Yusuf Yazici8, 1Istanbul University‒Cerrahpaşa, Cerrahpaşa Medical School and Behçet’s Disease Research Center, İstanbul, Turkey, 2Kantonsspital St. Gallen, St.Gallen, Switzerland, 3Musashi Kosugi Hospital, Kawasaki, Japan, 4Yonsei University College of Medicine and Severance Hospital, Seoul, Republic of Korea, 5Istanbul University‒Cerrahpaşa, İstanbul, Turkey, 6Amgen Inc., Thousand Oaks, CA, 7Amgen Inc., Gilbert, AZ, 8New York University School of Medicine, New York, NY

    Background/Purpose: Painful, recurring oral ulcers (OU) associated with Behçet’s syndrome negatively affect quality of life (QoL). Differences across sexes were reported in the frequency of…
  • Abstract Number: 1870 • ACR Convergence 2021

    Comparative Study on Anti-TNF vs Tocilizumab for Treatment of Refractory Uveitic Cystoid Macular Edema Due to Behcet’s Disease: Multicenter Study of 49 Patients

    Belén Atienza-Mateo1, Iván Ferraz-Amaro2, Emma Beltrán Catalán3, Alfredo Adán4, Marisa Hernandez Garfella5, Lucía Martínez-Costa6, Miguel Cordero Coma7, Manuel Diaz-Llopis8, José M. Herreras9, Ana Blanco10, Ignacio Torre11, David Díaz-Valle12, Antonio Atanes-Sandoval13, Felix Hernandez14, Santos Insua15, Julio Sánchez16, raquel almodovar17, Oscar Ruiz-Moreno18, Myriam Gandia Martinez19, Joan M. Nolla20, José Luis Martin-Varillas21, Vanesa Calvo-Río22, Diana Prieto-Peña23, Miguel Ángel gonzalez-Gay24 and Ricardo Blanco22, 1Group "Research in genetic epidemiology and atherosclerosis of systemic diseases and in bone metabolic diseases of the locomotor system", IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 3Hospital del Mar, Barcelona, Spain, 4Hospital Clinic, Barcelona, Spain, 5Hospital General Universitario de Valencia, Valencia, Spain, 6Hospital Peset, Valencia, Valencia, Spain, 7Hospital de León, Leon, Spain, 8Hospital Universitario La Fe, Valencia, Spain, 9Hospital Universitario IOBA, Valladolid, Spain, 10Hospital Universitario de Donostia, San Sebastián, 11Hospital Universitario de Basurto, Bilbao, Spain, 12Hospital Clínico San Carlos, Madrid, Madrid, Spain, 13Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain, 14Hospital Doctor Negrín, Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain, 15Hospital Universitario Santiago de Compostela, A Coruña, Spain, 16Hospital Universitario 12 de Octubre, Madrid, Spain, 17Hospital Universitario Fundación de Alcorcón, Madrid, Spain, 18Hospital Universitario Miguel Servet, Zaragoza, Zaragoza, Spain, 19Hospital Puerta del Mar, Cádiz, Spain, 20Hospital Universitario de Bellvitge, Barcelona, Barcelona, Spain, 21Hospital Sierrallana, Torrelavega, Spain, 22Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 23Hospital Universitario Marqués de Valdecilla, santander, Spain, 24Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose: Posterior segment involvement is the most serious affection of uveitis in Behçet’s disease (BD), with cystoid macular edema (CME) being the leading cause of…
  • Abstract Number: 1873 • ACR Convergence 2021

    The Importance of Lower Extremity Vein Wall Thickness in Patients with Behcet’s Syndrome

    Hasan Emre Kocabay1, M. Enes Yayla2, Evren Ustuner1, Emine Uslu yurteri3, Emine Aydemir Guloksuz4, Serdar Sezer2, Kinikli Gulay4, Murat Turgay4 and Askin Ates4, 1Ankara University, Ankara, Turkey, 2Ankara Training and Research Hospital, Ankara, Turkey, 3Hatay Training and Research Hospital, Hatay, Turkey, 4Ankara University Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey

    Background/Purpose: Behçet’s syndrome (BS) is a multisystemic chronic vasculitic disease that has mucocutaneous and joint involvement in addition to vascular, neurological and gastrointestinal involvement (1).…
  • Abstract Number: 1876 • ACR Convergence 2021

    A Prospective Observational Cohort Study and Systematic Review of 40 Patients with Mouth and Genital Ulcers with Inflamed Cartilage (MAGIC) Syndrome

    Yiming Luo1, Ertugrul Bolek1, Kaitlin Quinn2, Kristina Wells3, Emily Rose4, Emily Rominger1, Levent Kilic5, Omer Karadag6, Cindy Clark1, Alicia Livinski1, Peter Grayson7 and Marcela Ferrada1, 1National Institutes of Health, Bethesda, MD, 2National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, 3National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 4Case Western, Cleveland Heights, OH, 5Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 6Hacettepe University, Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara, Turkey, 7National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD

    Background/Purpose: Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome is a rare and poorly understood entity with clinical features of both relapsing polychondritis (RP)…
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