Date: Monday, November 8, 2021
Session Type: Poster Session C
Session Time: 8:30AM-10:30AM
Background/Purpose: Ophthalmological involvement is one of the most feared manifestations of Behçet’s disease.The aim of this study was to define the main demographic and clinical features of ophthalmological involvement in a well-defined cohort of patients with Behçet’s disease.
Methods: Descriptive study of a cohort of 120 patients diagnosed with Behçet’s disease from January 1, 1980 to December 31, 2019. Finally, following the 2014 International Criteria for Behçet’s Disease (ICBD) (J Eur Acad Dermatol Venereol 2014; 28:338-47) 94 patients were chosen for this study.
Results: 50 patients (28 men/22 women; male to female ratio of 1:0.8) had ocular involvement. Mean age at diagnosis was 37.6±11.8 years. Mean ICBD score was 5.8±1.3 points. Neurological involvement was the most frequent manifestation in this group. Genital ulcers were more frequent in the non-ophthalmological involvement group. Systemic clinical domains are shown in Figure.
The most frequent ocular manifestations were uveitis (n=44, 88.0%), retinal vasculitis (n=5, 10%) and dry eye (n=5, 10%). Likewise, the most frequent type of uveitis was anterior (n=17, 38.6%), followed by posterior uveitis (n=14, 31.8%). 26 (59.1%) of all uveitis were unilateral. Panuveitis was more frequent among patients under 60 years. Similarly, anterior uveitis was predominant in patients older than 70 years. There were no remarkable differences between genders. Main clinical features are shown in Table.
Conclusion: Ophthalmological involvement in Behçet’s disease was more frequent in men. Uveitis and retinal vasculitis were the most frequent ocular manifestation. No remarkable differences in clinical features were observed between genders.
To cite this abstract in AMA style:Herrero-Morant A, Suárez-Amorín G, Demetrio-Pablo R, Sánchez-Bilbao L, Álvarez-Reguera C, Martinez-Lopez D, Fernandez R, Martin-Varillas J, Mata-Arnaiz C, gonzalez-Gay M, Blanco R. Epidemiology and Clinical Features of Ophthalmological Manifestations in Behçet’s Disease: Study of 50 Patients of a Series of 120 Patients in a Region in Northern Spain [abstract]. Arthritis Rheumatol. 2021; 73 (suppl 9). https://acrabstracts.org/abstract/epidemiology-and-clinical-features-of-ophthalmological-manifestations-in-behcets-disease-study-of-50-patients-of-a-series-of-120-patients-in-a-region-in-northern-spain/. Accessed January 27, 2023.
« Back to ACR Convergence 2021
ACR Meeting Abstracts - https://acrabstracts.org/abstract/epidemiology-and-clinical-features-of-ophthalmological-manifestations-in-behcets-disease-study-of-50-patients-of-a-series-of-120-patients-in-a-region-in-northern-spain/