Abstracts tagged "adipose tissue"

Abstract Number: 1766 • 2018 ACR/ARHP Annual Meeting
Abdominal Adipose Tissue Predicts Incident Major Cardiovascular Events in Systemic Necrotizing Vasculitis Patients: Data from a Prospective Cohort Study on 120 Patients
Soledad Henriquez¹, Bertrand Dunogué², Alexis Régent¹, Pascal Cohen³, Alice Bérezné¹, Sami Kolta⁴, Claire Le Jeunne¹, Luc Mouthon⁵, Christian Roux⁴, Loïc Guillevin⁶, Karine Briot⁷ and Benjamin Terrier⁸, ¹Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ²Internal Medicine, Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ³Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, Hôpital Cochin, Université Paris Descartes, Sorbonne Paris Cité, Paris, France, ⁴Department of Rheumatology, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ⁵Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France, ⁶Medecine Interne, Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ⁷Department of Rheumatology, Cochin Hospital and Epidemiology and Biostatistics Unit,Sorbonne Paris Cité Reserach Center,Paris Descartes University,INSERM U1153, Paris, France, ⁸National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France
Background/Purpose: Cardiovascular (CV) events are highly prevalent in patients with systemic necrotizing vasculitides (SNV). The visceral/subcutaneous adipose tissue (VAT/SAT) ratio has been shown to be…
Abstract Number: 55 • 2018 ACR/ARHP Annual Meeting
Adipose Derived Stem Cell Suppressed Synovial Inflammation and Repaired Cartilage Destruction in Rheumatoid Arthritis Model Mice
Tadashi Okano¹, Kentaro Inui², Hideki Ueyama³, Kumi Orita³, Tatsuya Koike⁴ and Hiroaki Nakamura², ¹Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ³Osaka City University Graduate School of Medicine, Osaka, Japan, ⁴Center for Senile Degenerative Disorders, Osaka City University Graduate School of Medicine, Osaka, Japan
Background/Purpose: Adipose derived stem cell (ADSC) is one of the stem cells produced by adipose tissue which can be collected easily and in large quantities.…
Abstract Number: 85 • 2018 ACR/ARHP Annual Meeting
Antibodies to Citrullinated Protein Antigens (ACPAs) Induce Adipose Tissue Dysfunction Contributing to the Cardiovascular Disease Risk in Rheumatoid Arthritis. Modulation By Biological Dmards
Nuria Barbarroja¹, Ivan Arias de la Rosa², Miriam Ruiz-Ponce³, Maria Dolores de la Rosa-Garrido³, Patricia Ruiz-Limon⁴, Yolanda Jiménez-Gómez¹, Carlos Perez-Sanchez¹, Maria Carmen Abalos-Aguilera², Rocio Guzman-Ruiz⁵, Maria del Mar Malagon⁶, Francisco Jose Tinahones⁷, Eduardo Collantes-Estévez¹, Chary Lopez-Pedrera³ and Alejandro Escudero-Contreras², ¹Rheumatology service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ²Rheumatology Service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ³IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ⁴Research Group of Endocrine Diseases, Research Laboratory. Biomedical Research Institute of Malaga (IBIMA).Virgen de la Victoria Universitary Hospital, Malaga, Spain., Málaga, MA, Spain, ⁵Department of Cell Biology, Physiology, and Immunology,, IMIBIC/University of Córdoba/Reina Sofía University Hospital, Cordoba, Spain, ⁶Department of Cell Biology, Physiology, and Immunology,I, IMIBIC/University of Córdoba/Reina Sofía University Hospital, Cordoba, Spain, ⁷Department of Clinical Endocrinology and Nutrition, Institute of Biomedical Research of Málaga (IBIMA), Hospital of Málaga (Virgen de la Victoria), University of Málaga (UMA), Málaga, Spain; CIBER Fisiopatología Obesidad y Nutrición, Instituto de Salud Ca, Malaga, Spain
Background/Purpose: 1) To test the relationship among ACPAs and levels of adipocytokines and atherosclerosis in RA patients. 2) To analyze the effects of ACPAs on…
Abstract Number: 503 • 2018 ACR/ARHP Annual Meeting
Waist Circumference Based Abdominal Obesity Versus Body Mass Index in Rheumatoid Arthritis: Influence on the Risk of Diabetes and Cardiovascular Disease
Gulsen Ozen¹, Sofia Pedro² and Kaleb Michaud^1,2, ¹Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS
Background/Purpose: Adipose tissue deposited around the mesentery is highly associated with insulin resistance and cardiovascular disease (CVD). Compared to BMI, waist circumference (WC) has been…
Abstract Number: 1618 • 2018 ACR/ARHP Annual Meeting
Adipose Tissue Inflammation in Psoriatic Arthritis: Overexpression of a Wide Array of Inflammatory Mediators and Associations with Disease and Treatment Characteristics
Jae Hee Yun¹, Robert Winchester², Hui-Zhu Zhang², Christopher Depender¹ and Jon T. Giles¹, ¹Medicine/Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ²Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Obesity is associated with PsA risk, severity, and lack of response to DMARDs. However, no studies have explored adipose tissue inflammation at the molecular…
Abstract Number: 51 • 2017 ACR/ARHP Annual Meeting
Irisin Ameliorates Infrapatellar Adiposity in Knee Osteoarthritis Pathogenesis By Orchestrating Adipokine Signaling
Feng-Sheng Wang¹, Yi-Chih Sun¹ and Jih-Yang Ko², ¹Core Facility for Phenomics & Diagnostics, Department of Medical Research, Core Facility for Phenomics & Diagnostics, Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital, Taiwan, Kaohsiung, Taiwan, ²Department of Orthopedic Surgery, Department of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital, Taiwan, Kaohsiung, Taiwan
Background/Purpose: Aberrant infrapatellar fat metabolism is a prominent feature that exacerbates inflammation and fibrosis relative to joint deterioration during osteoarthritis (OA). Irisin, a secretory subunit…
Abstract Number: 54 • 2017 ACR/ARHP Annual Meeting
Maintaining Angiogenesis Prevents Glucocorticoid Induced Osteonecrosis
Alanna Dubrovsky¹, Wei Yao¹, Geetha Mohan¹, Mie Jin Lim¹, Yu-An Evan Lay¹, Donald Kimmel² and Nancy E. Lane^3,4,5,6,7,8, ¹UC Davis Center for Musculoskeletal Health, Sacramento, CA, ²Creighton University School of Medicine Osteoporosis Research Center, Omaha, NE, ³Center for Musculoskeletal Health, University of California, Davis School of Medicine, Sacramento, CA, ⁴Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ⁵UC Davis Medical Center, Sacramento, CA, ⁶Center for Musculoskeletal Health, Univ of California at Davis, Sacramento, CA, ⁷Medicine, U.C. Davis, Sacramento, CA, ⁸UCDMC, Sacramento, CA
Background/Purpose: Atraumatic osteonecrosis (ON) results from reduced bone vascularity. Glucocorticoids (GC) are a major risk factor for ON, as GCs reduce vascular endothelial growth factor,…
Abstract Number: 570 • 2017 ACR/ARHP Annual Meeting
Signalling Pathways Identified in Salivary Glands from Primary Sjögren’s Syndrome Patients Reveal Enhanced Adipose Tissue Development, As Demonstrated By Microarray Analysis, Real-Time PCR and Immunohistochemistry
Lara A Aqrawi¹, Janicke C Liaaen Jensen¹, Gunnvor Øijordsbakken², Ann-Kristin Ruus³, Ståle Nygård^4,5, Marit Holden⁶, Roland Jonsson^7,8, Hilde Kanli Galtung⁹ and Kathrine Skarstein^10,11, ¹Department of Oral Surgery and Oral Medicine, University of Oslo, Oslo, Norway, ²Department of Clinical Medicine, University of Bergen, Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway, ³Department of Oral Biology, University of Oslo, Oslo, Norway, ⁴Department of Informatics, University of Oslo, Oslo, Norway, ⁵Bioinformatics core facility, Institute for Cancer research, Oslo University Hospital, Oslo, Norway, ⁶Norwegian Computing Center, Oslo, Oslo, Norway, ⁷Broegelmann Research laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, ⁸Department of Rheumatology, Haukeland University Hospital, Bergen, Bergen, Norway, ⁹Department of Oral Biology, University of Oslo, Oslo, Pakistan, ¹⁰Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway, ¹¹Department of Pathology, Haukeland University Hospital, Bergen, Bergen, Norway
Background/Purpose: : A characteristic feature of Sjögren’s syndrome (SS) is the destruction of salivary and lacrimal glands mediated by mononuclear cell infiltration. Adipocytes can also…
Abstract Number: 1961 • 2017 ACR/ARHP Annual Meeting
Risk Factors for Low Muscle MASS in Community-Dwelling Older Women: A Population-Based Prospective Cohort Study in Brazil. the São Paulo Ageing & Health Study
Ketty Machado¹, Diogo S Domiciano², Luana G Machado³, Jaqueline B Lopes⁴, Camille P Figueiredo⁵, Valéria F. Caparbo³, Liliam Takayama³, Paulo Menezes⁶ and Rosa M R Pereira², ¹Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, ³Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil, ⁵Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil, ⁶Preventive medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Sarcopenia is a syndrome characterized by progressive loss of skeletal muscle mass, which results in decreased muscle strength and impairment of functional capacity. Moreover,…
Abstract Number: 2372 • 2017 ACR/ARHP Annual Meeting
Obesity and the Impact on Treat to Target Goals and Functional Ability in RA. Results from Two Multi-Centre UK Inception Cohorts
Elena Nikiphorou¹, Sam Norton², Patrick Kiely³ and Adam Young⁴, ¹Academic Rheumatology Department, King's College London, London, United Kingdom, ²Academic Rheumatology, King´s College London, London, United Kingdom, ³St George's Hospital, London, United Kingdom, ⁴University of Hertfordshire, Hertford, United Kingdom
Background/Purpose: The links between inflammation, obesity and joint dysfunction are well established. How these translate into clinical disease activity and functional disability in rheumatoid arthritis…
Abstract Number: 2961 • 2017 ACR/ARHP Annual Meeting
Body Composition and Myokine Levels in Juvenile Dermatomyositis and Associations with Physical Function
Birgit Nomeland Witczak¹, Kristin Godang², Jens Bollerslev^2,3, Thomas Schwartz^4,5, Berit Flatø^3,6, Ivar Sjaastad^3,4,7 and Helga Sanner^6,8, ¹Oslo University Hospital, Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ²Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ³Institute for Clinical Medicine, University of Oslo, Oslo, Norway, Oslo, Norway, ⁴Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁵Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁶Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ⁷Department of Cardiology, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁸Norwegian National Advisory Unit on Rheumatic Diseases in Children and Adolescents, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway
Background/Purpose: JDM presents with proximal muscle weakness and atrophy is frequent. Still, body composition (BC) in JDM has not been widely studied, but is known…
Abstract Number: 1363 • 2016 ACR/ARHP Annual Meeting
Serum Adipokines in Juvenile Dermatomyositis Are Associated with Disease Activities and Cardiac Function
Birgit Nomeland Witczak¹, Kristin Godang², Thomas Schwartz³, Nicoleta Cristina Olarescu⁴, Berit Flatø^5,6, Jens Bollerslev^5,7, Ivar Sjaastad^5,8,9 and Helga Sanner^5,6, ¹Oslo University Hospital, Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ²Department of Specialised Endocrinology, Oslo University Hospital, Section of Specialised Endocrinology, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ³Department of Infectious Diseases, Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁴Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Section of Specialised Endocrinology, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ⁵Institute for Clinical Medicine, University of Oslo, Oslo, Norway, Oslo, Norway, ⁶Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ⁷Section of Specialised Endocrinology, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ⁸Department of Cardiology, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁹Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, Oslo, Norway
Background/Purpose: We have earlier demonstrated redistribution of adipose tissue in JDM patients. There is an increase in visceral adipose tissue (VAT), a highly active metabolic…
Abstract Number: 1512 • 2016 ACR/ARHP Annual Meeting
Bone Structural Deficits in Rheumatoid Arthritis: Impact of Muscle Mass and Density
Joshua Baker¹, Jin Long², Babette S. Zemel³, Janet E. Dinnella⁴, Prerna Sharma⁵, Said Ibrahim⁶ and Mary B. Leonard⁷, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Stanford University, Palo Alto, CA, ³Pediatrics, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ⁴Arthritis/Immun Center, U Penn & VA Med Ctr, Philadelphia, PA, ⁵University of Pennsylvania, Philadelphia, PA, ⁶Medicine, University of Pennsylvania, Philadelphia, PA, ⁷Pediatrics, Division of Nephrology, Stanford School of Medicine, Stanford University, Palo Alto, CA
Background/Purpose: Rheumatoid arthritis (RA) is associated with muscle loss, obesity, and osteoporotic fractures. Body composition and muscle quality are important regulators of bone strength among…
Abstract Number: 1858 • 2016 ACR/ARHP Annual Meeting
Phenotypical and Functional Characteristics of in Vitro Expanded Adipose-Derived Mesenchymal Stem Cells from Patients with Systemic Sclerosis
Nicoletta Del Papa¹, Chiara Capelli², Eleonora Zaccara¹, Paola Cipriani³, Paola Di Benedetto⁴, Wanda Maglione¹, Romina Andracco¹, Francesca Pignataro¹, Roberto Giacomelli⁴, Martino Introna⁵ and Claudio Vitali⁶, ¹Dept. Rheumatology, G. Pini Hospital, Milano, Italy, ²Laboratorio di Terapia Cellulare e Genica "G. Lanzani",, Ospedali Riuniti di Bergamo, Bergamo, Italy, ³Department of Biotechnological and Applied Clinical Science, Rheumatology Unit, School of Medicine, University of L’Aquila, L'Aquila, Italy, ⁴Department of Biotechnological and Applied Clinical Science, Rheumatology Unit, School of Medicine, University of L’Aquila, L’Aquila, Italy, ⁵Laboratorio di Terapia Cellulare e Genica "G. Lanzani", Ospedali Riuniti di Bergamo, Bergamo, Italy, ⁶Rheumatology Section, Istituto San Giuseppe, Como, Italy
Background/Purpose: Adult stem cells, namely those of mesenchymal origin (MSCs), have received attention as an ideal source of regenerative cells because of their multi-potential ability…
Abstract Number: 1948 • 2016 ACR/ARHP Annual Meeting
Evaluation of Body Composition Parameters in Granulomatosis with Polyangiitis: Association of Fat Mass Parameters with Disease Activity and Inflammatory Markers
Mariana O Perez¹, Valeria F Caparbo², Mauricio Levy-Neto² and Rosa M R Pereira², ¹Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Granulomatosis with polyangiitis (GPA, Wegener´s) patients are more exposed to traditional cardiovascular risk factor, including obesity. In rheumatic diseases, inflammation has been associated with…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].