Abstracts tagged "Spondylarthritis"

Abstract Number: 633 • 2019 ACR/ARP Annual Meeting
Diagnostic Delay in Spondyloarthritis
Santiago Scarafia¹, Maria Paula Girard Bosch ², Mariana Benegas ³, Vanesa Cosentino ⁴, Josefina Marin ⁵, Vanesa Duarte ⁶, Juan Bande ⁷, Maria Julieta Gamba ⁸, Fernando Sommerfleck ⁹, Paula Gonzalez ⁸, Diego Vila ¹⁰, Marina Oliver ¹¹, Maria Mercedes Piovesan ¹², Rodrigo Aguila ¹³, Velozo Edson Javier ¹⁴, Eduardo Kerzberg ¹⁵, Maria Janina Tapia Moreira ¹⁶, Micaela Cosatti ¹⁷, Carla Airoldi ¹⁸, Mercedes Garcia ¹⁹ and Maria Victoria Martire ²⁰, ¹Hospital Municipal "San Cayetano", Buenos Aires, Buenos Aires, Argentina, ²Instituto Médico Platense, La Plata, ³Sanatorio Mendez, Buenos Aires, ⁴Federación de Asociaciones de Trabajadores de la Sanidad Argentina Buenos Aires, Buenos Aires, Argentina, ⁵Hospital Italiano de Buenos Aires, buenos aires, Ciudad Autonoma de Buenos Aires, Argentina, ⁶Clínica Monte Grande, Monte Grande, Buenos Aires, Argentina, ⁷Hospital General de Agudos Dr. E. Tornú, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ⁸Hospital Nacional Posadas, Buenos Aires, Buenos Aires, Argentina, ⁹Sanatorio Mendez, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁰Centro Médico Ginecológico Zárate, Zárate, Buenos Aires, Argentina, ¹¹Hospital Privado de Comunidad de Mar del Plata, Mar del Plata, Buenos Aires, Argentina, ¹²Sanatorio Finochietto, Buenos AIres, Ciudad Autonoma de Buenos Aires, Argentina, ¹³HIZGA "San Martin", La Plata, Buenos Aires, Argentina, ¹⁴Sanatorio Adventista del Plata, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁵Hospital Ramos Mejia, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ¹⁶Hospital Ramos Mejia, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁷CEMIC, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁸Hospital Provincial de Rosario, Rosario, Santa Fe, Argentina, ¹⁹Hospital San Martín, La Plata, Argentina, ²⁰Hospital San Martín. Instituto Médico Platense, La Plata
Background/Purpose: Spondyloarthritis (Spa) is an heterogeneous group of diseases. Diagnostic delay contributes to poor patient outcome. Prompt diagnosis of Spa is the first step towards…
Abstract Number: 2494 • 2019 ACR/ARP Annual Meeting
Comparison of Comorbidity in Spondyloarthritis: Influence on Inflammatory Activity in Patients with Psoriatic Arthritis
Luis Gomez-Lechon¹, Maria Elisa Acosta ¹, Guadalupe Manzano Canabal ¹, Olga Compan ¹, Cristina Hidalgo ², Olga Martinez ¹, Ana Turrión ¹, Javier del Pino ¹ and Carlos Montilla ¹, ¹Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ²Hospital Clínico Universitario de Salamanca, Salamanca, Castilla y Leon, Spain
Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous disease that is included in the group of spondyloarthritis. Although PsA has its own clinical characteristics, it has…
Abstract Number: 634 • 2019 ACR/ARP Annual Meeting
Targeted 1H NMR Based Metabolomics Analysis Revealed Significantly Higher Synovial Phe/Tyr Ratio in Reactive Arthritis and Undifferentiated Spondyloarthropathy
Hafis Muhammed¹, Dinesh Kumar ², Durgesh Dubey ², Sandeep Kumar ³, Smriti Chaurasia ³, Anupam Guleria ², Sanjukta Majumder ³, Rajeev Singh ³, Vikas Agarwal ¹ and Ramnath Misra ⁴, ¹SGPGI, Lucknow, Uttar Pradesh, India, ²Centre for Biomedical Research, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India, ³Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India, ⁴Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Lucknow, Uttar Pradesh, India
Background/Purpose: Elevated phenylalanine-to-tyrosine ratio (Phe/Tyr) is a marker of oxidative stress. We hypothesized that the synovial Phe/Tyr in reactive arthritis is higher than Rheumatoid arthritis(RA)…
Abstract Number: 934 • 2019 ACR/ARP Annual Meeting
Predictors of Survival of Secukinumab Treatment in a Multicenter Cohort of 556 Spondylarthritis
Benoit Flachaire¹, Jean-Guillaume Letarouilly ², Céline Labadie ³, Nicolas Cohen ⁴, Vincent Pradel ⁵, Jérémie Sellam ⁶, Pascal Richette ⁷, Philippe Dieudé ⁸, Pascal Claudepierre ⁹, Bruno Fautrel ¹⁰, Eric Houvenagel ¹¹, Chi Duc Nguyen ¹², Marie-Hélène Guyot ¹³, Nicolas Segaud ¹⁴, Frédéric Maury ¹⁵, Laurent Marguerie ¹⁶, Xavier Deprez ¹⁷, Jean-Hugues Salmon ¹⁸, Guy Baudens ¹⁹, Elisabeth Gervais ²⁰, Corinne Miceli-Richard ²¹, Isabelle Chary-Valckenaere ²², Pierre Lafforgue ²³, Damien Loeuille ²⁴, Christophe Richez ²⁵, René-Marc Flipo ²⁶ and Thao Pham ²³, ¹Aix-Marseille University, CHU Marseille, department of Rheumatology, 13,000 Marseille, France, Marseille, Provence-Alpes-Cote d'Azur, France, ²University of Lille, CHU Lille, department of rheumatology, 59,000 Lille, France, Lille, Nord-Pas-de-Calais, France, ³Bordeaux University, CHU Bordeaux, department of Rheumatology, 33,000 Bordeaux, France, Bordeaux, Aquitaine, France, ⁴APHM -Assistance publique des hôpitaux de Marseille, Marseille, France, ⁵APHM -Assistance publique des hôpitaux de Marseille, Marseille, Finland, ⁶Service de Rhumatologie, AP-HP Hôpital Saint-Antoine, Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France, Paris, France, ⁷Department of Rheumatology, AP-HP Lariboisiere Hospital, Paris, France, ⁸Rheumatology, Bichat Hospital, APHP, Paris;, Paris, France, ⁹Rheumatology, CHU Henri Mondor Créteil, Paris, France, ¹⁰Pitié-Salpêtrière Hospital, Department of Rheumatology, AP-HP, Sorbonne University, UPMC university, Paris, Ile-de-France, France, ¹¹Rheumatology, Saint Philibert Hospital, Lille Cathololic Institute, Lomme, Lomme, France, ¹²Rheumatology, Hospital of Béthune, Béthune, Béthune, France, ¹³Rheumatology, Hospital of Roubaix, Roubaix, Roubaix, France, ¹⁴Internal Medicine, Hospital of Armentières, Armentières, Armentières, France, ¹⁵Rheumatology, Private Practice, Beuvry, Beuvry, France, ¹⁶Rheumatology, Calot Institute, Berck, Berck-sur-Mer, ¹⁷Rheumatology, Hospital of Valenciennes, Valenciennes, Valenciennes, France, ¹⁸Rheumatology, Reims University Hospital, Reims, Reims, France, ¹⁹Rheumatology, Private Practice, Valenciennes, Valenciennes, France, ²⁰CHU de Poitiers, Rheumatology, Poitiers, France, ²¹Paris Descartes University, Department of Rheumatology - Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, ²²Centre Hospitalier Universitaire de Nancy, VANDOEUVRE, France, ²³Aix-Marseille University, CHU Marseille, department of Rheumatology, 13,000 Marseille, France, Marseille, France, ²⁴Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France, ²⁵Pellegrin Hospital, University Hospital of Bordeaux, Bordeaux, France, ²⁶University of Lille, CHU Lille, department of rheumatology, 59,000 Lille, France, Lille, France
Background/Purpose: Secukinumab (SEC) is an interleukin-17 inhibitor used to treat patients with axial spondylarthritis (axSpA) and psoriatic arthritis (PsA). Drug survival is often used as…
Abstract Number: 1002 • 2019 ACR/ARP Annual Meeting
Beneficial Effect of Angiotensin Receptor Blocker in a Spondyloarthritis Animal Model
Seung-Cheol Shim¹, Jin-Sun Choi ², Ji-Young Kim ² and Chan-Geol Park ², ¹Division of Rheumatology, Department of Internal Medicine, School of Medicine, Chungnam National University, Chungnam National University Hospital, Daejeon, Republic of Korea, ²Chungnam National University Hospital, Daejeon, Republic of Korea
Background/Purpose: Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to be efficacious in the treatment of the signs and symptoms of spondyloarthritis (SpA). However, NSAIDs have…
Abstract Number: 687 • 2018 ACR/ARHP Annual Meeting
Clinical Characteristics of Spondyloarthritis Patients in Japan in Comparison to Other Regions of the World
Haruki Sawada¹, Kazuki Yoshida², Naomi Ichikawa³, Hisashi Inoue⁴, Yuko Kaneko⁵, Taku Kawasaki⁶, Kazuo Matsui⁷, Mitsuhiro Morita⁸, Kurisu Tada⁹, Naoho Takizawa¹⁰, Naoto Tamura⁹, Atsuo Taniguchi³, Yoshinori Taniguchi¹¹, Shigeyoshi Tsujii¹², Yoichiro Haji¹³, Masei Suda¹⁴, Haruyuki Yanaoka¹⁵, Ryo Rokutanda¹⁴, Masato Okada¹⁴, Clementina López Medina¹⁶, Anna Molto¹⁷, Maxime Dougados¹⁶, Désirée van der Heijde¹⁸, Shigeto Kobayashi¹⁹, Tetsuya Tomita²⁰ and Mitsumasa Kishimoto¹⁴, ¹Immuno-rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, ²Departments of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, ³Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ⁴Department of Orthopedic Surgery, Juntendo University School of Medicine, Tokyo, Japan, ⁵Department of Internal Medicine, Division of Rheumatology, Keio University School of Medicine, Tokyo, Japan, ⁶Department of Orthopedic Surgery, Shiga University of Medical Science, Shiga, Japan, ⁷Department of Rheumatology, Tonan Hospital, Hokkaido, Japan, ⁸Department of Orthopedic Surgery, Fujita Health University, Aichi, Japan, ⁹Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo, Japan, ¹⁰Department of Rheumatology, Chubu Rosai Hospital, Aichi, Japan, ¹¹Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi, Japan, ¹²Department of Orthopedics, Osaka Minami Medical Center, Osaka, Japan, ¹³Department of Rheumatology, Daido Hospital, Aichi, Japan, ¹⁴Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, ¹⁵St. Luke's International Hospital, Tokyo, Japan, ¹⁶Department of Rheumatology, Paris Descartes University, Cochin Hospital, Paris, France, ¹⁷Department of Rheumatology, Paris Descartes University, Cochin Hospital, Paris, Japan, ¹⁸Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ¹⁹Department of Internal Medicine, Juntendo University Koshigaya Hospital, Saitama, Japan, ²⁰Department of Orthopaedic Biomaterial Science, Osaka University Graduate School of Medicine, Osala, Japan
Background/Purpose: To delineateclinical characteristicsof patients with spondyloarthritis (SpA) in Japan in comparison to other areas of the world. Methods: Utilizingthe COMOSPA data, an international cross-sectional…
Abstract Number: 1613 • 2018 ACR/ARHP Annual Meeting
Dactylitis in Early Spondyloarthritis. Baseline Data from a Prospective French National Cohort
Daniel Wendling¹, Clément Prati², Alain Saraux³, Anna Molto⁴, Thao Pham⁵, Maxime Dougados⁶ and Xavier Guillot⁷, ¹Rheumatology, University Hospital - Bourgogne Franche Comté University, Besançon, France, ²Rheumatology, University Hospital - Bourgogne Franche Comté University, Besancon, France, ³Rheumatology, CHU Brest, Brest, France, ⁴Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ⁵Rheumatology Department, Aix-Marseille University, APHM, Marseille, France, ⁶Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁷PEPITE EA 4267, Bourgogne-Franche-Comté university, Besançon, France
Background/Purpose: Dactylitis is a particular feature shared across the several phenotypical forms of spondyloarthritis (SpA), part of the classification criteria. There are only few data…
Abstract Number: 1622 • 2018 ACR/ARHP Annual Meeting
ASAS Consensus on Spanish Nomenclature for Spondyloarthritis
Victoria Navarro-Compán¹, Teresa Oton-Sanchez², Estibaliz Loza³, Raquel Almodóvar González⁴, Rafael Ariza⁵, Wilson Bautista-Molano⁶, Rubén Burgos-Vargas⁷, Eduardo Collantes Estevez⁸, Eugenio De Miguel⁹, Carlos M Gonzalez¹⁰, Jordi Gratacos-Masmitja¹¹, Sebastián Ibáñez¹², Xavier Juanola¹³, José A. Maldonado-Cocco¹⁴, Anna Molto¹⁵, Juan D. Mulero¹⁶, Cesar Pacheco-Tena¹⁷, Cesar Ramos-Remus¹⁸, Jesus Sanz¹⁹, Rafael Valle-Oñate²⁰, Pedro Zarco²¹ and Helena Marzo-Ortega²², ¹Immuno-Rheumatology research group, IdiPaz. La Paz University Hospital, Madrid, Spain, ²InMusc. Instituto de Salud Músculo-Esquelética, Madrid, Spain, ³INMUSC, Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain, ⁴Rheumatology, Hospital Universitario Fundación Alcorcón. Madrid. Spain, Madrid, Spain, ⁵Rheumatology, Hospital Universitario Virgen Macarena, Sevilla, Spain, ⁶Hospital Militar, Bogotá, Colombia, ⁷Department of Rheumatology, Hospital General de México "Dr. Eduardo Liceaga", Mexico City, Mexico, ⁸IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ⁹Rheumatology, University Hospital La Paz, IdiPaz, Madrid, Spain, ¹⁰Servicio de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ¹¹Rheumatology, Hospital Parc Taulí, Sabadell - Barcelona, Spain, ¹²Rheumatology Department, Clínica Alemana de Santiago, Santiago, Chile, ¹³Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ¹⁴Buenos Aires University, Consulting Professor of Rheumatology, Buenos Aires University. Argentina, Buenos Aires, Argentina, ¹⁵Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ¹⁶Hospital Puerta de Hierro, Majadahonda, Madrid, Spain, ¹⁷Universidad Autónoma de Chihuahua, Hospital Christus Muguerza del Parque, Chihuahua, Mexico, ¹⁸Universidad Autonoma de Guadalajara, Zapopan, Mexico, ¹⁹Rheumatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, ²⁰Unidad de Reumatologia, Hospital Militar, Bogota, Colombia, ²¹H Fundación Alcorcón, Alcorcón, Spain, ²²NIHR LBRC, LTHT and LIRMM, UoL, Leeds, United Kingdom
Background/Purpose: In the last three decades, major advances in the spondyloarthritis (SpA) field have been achieved leading to new terminology. Whilst this terminology is well…
Abstract Number: 2574 • 2018 ACR/ARHP Annual Meeting
Tapering TNF Inhibitors in Axial Spondyloarthritis: Systematicanalysisoftheliteratureandmeta-Analysis
Loukianos Couvaras¹, Thomas Barnetche², Arnaud Constantin³ and Thao Pham⁴, ¹Rheumatology, Aix-Marseille University, APHM, Marseille, France, ²Rheumatology Department, FHU ACRONIM, Bordeaux University Hospital, Bordeaux, France, ³Department of Rheumatology, Purpan Hospital, Toulouse III University, Toulouse, France, Toulouse, France, ⁴Rheumatology Department, Aix-Marseille University, APHM, Marseille, France
Background/Purpose: Tumor necrosis factor inhibitors (TNFi) are effective in treating patients with axial spondyloarthritis (axSpA), but they are associated with adverse effects and high costs.…
Abstract Number: 1516 • 2017 ACR/ARHP Annual Meeting
Effectiveness of Certolizumab Pegol in Patients with Uveitis Associated to Spondyloarthritis Refractory to Other Tumour Necrosis Factor Inhibitors
M. Victoria Hernández¹, Marina Mesquida¹, Victor Llorens², Maite Sainz de la Maza², Ricardo Blanco³, Vanesa Calvo⁴, Olga Maiz⁵, Ana Blanco⁶, Ana Urruticoechea-Arana⁷, Juan Ramon De Dios⁸, Pilar Ahijado-Guzman⁹, Enrique Judez¹⁰, Patricia Tejón¹¹, M Soledad Peña¹², Francisca Sivera¹³, Alfredo Adan¹ and Raimon Sanmarti¹⁴, ¹Hospital Clinic. Barcelona. Spain, Barcelona, Spain, ²Ophthalmology Department. Hospital Clínic of Barcelona, Barcelona, Spain, ³Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, ⁴Rheumatology Department. Hospital Universitario Marqués de Valdecilla., Santander, Spain, ⁵Hospital Donostia. Spain, San Sebastian, Spain, ⁶Ophthalmology Department. Hospital Donostia, San Sebastian, Spain, ⁷Rheumatology Department. Hospital Can Misses, IBIZA, Spain, ⁸Rheumatology Department. Hospital Universitario de Araba, Vitoria, Spain, ⁹Rheumatology Unit. Fuenlabrada’s Hospital, Madrid, Madrid, Spain, ¹⁰Rheumatology Department. Hospital de Albacete, Albacete, Spain, ¹¹Rheumatology Department. Hospital Universitario General de Castellón, Castellon, Spain, ¹²Ophtalmology Department. Hospital Universitario General de Castellón, Castellon, Spain, ¹³Sección de Reumatología, Hospital General Universitario de Elda., Elda, Spain, ¹⁴Arthritis Unit, Rheumatology Dpt, Hospital Clinic of Barcelona, Barcelona, Spain
Background/Purpose: Uveitis is a common extra-articular manifestation in patients with spondyloarthritis (SpA) requiring, in most severe cases, the use of biological therapy, especially tumour necrosis…
Abstract Number: 1535 • 2017 ACR/ARHP Annual Meeting
Study of Potential Clinical and Biologic Predictors of Maintaining Good Response at 1 Year Follow-up, in Patients with Ankylosing Spondylitis Under Dose Reduction of TNFi Treatment
Mireia Moreno¹, Caridad Pontes², Ferran Torres³, Agusti Sellas-Fernandez⁴, Miriam Almirall⁵, Juan Carlos Torre-Alonso⁶, Teresa Clavaguera⁷, Carlos Rodriguez-Lozano⁸, Luis Francisco Linares⁹, Ana Urruticoechea-Arana¹⁰, Eduardo Collantes-Estevez¹¹, Rosa Morla¹², Delia Reina¹³, Eduardo Cuende¹⁴, Pedro Zarco¹⁵, Cruz Fernandez-Espartero¹⁶, Rosario García-Vicuña¹⁷, Jesus Sanz¹⁸, Xavier Juanola¹⁹, Antoni Vallano²⁰, Francisco J Blanco²¹, Raimon Sanmarti²², Gonzalo Calvo²³, Cristina Avendaño²⁴, Eugenio De Miguel²⁵, Roser Vives²⁶, Raul Veroz Gonzalez²⁷, Carlos Alberto Montilla-Morales²⁸ and Jordi Gratacos-Masmitja²⁹, ¹Rheumatology, Parc Tauli Hospital Universitari, Sabadell, Spain, ²Clinic Pharmacology, Parc Tauli Hospital Universitari. I3PT. UAB, Sabadell, Spain, ³Hospital Clinic de Barcelona, Barcelona, Spain, ⁴Rheumatology, Hospital Universitario Valle Hebron, Barcelona, Spain, ⁵Rheumatology, Hospital del Mar, Barcelona, Spain, ⁶H Monte Naranco, Oviedo, Spain, ⁷Rheumatology. Palamós Hospital, Rheumatologist, Catalonia, Spain, ⁸Rheumatology, Hospital Universitario Dr. Negrin, Gran Canaria, Spain, ⁹Rheumatology, Hospital Virgen de la Arrixaca. Murcia. Spain, Murcia, Spain, ¹⁰Rheumatology Department. Hospital Can Misses, IBIZA, Spain, ¹¹Rheumatology, IMIBIC-Hospital Universitario Reina Sofia, Cordoba, Spain, ¹²Rambla Vella, 14, Hospital La Tecla, Tarragona, Spain, ¹³Rheumatology, Hospital de Sant Joan Despí Moisès Broggi, Barcelona, Spain, ¹⁴University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, ¹⁵H Fundación Alcorcón, Alcorcón, Spain, ¹⁶Rheumatology, Hospital de Mostoles, Madrid, Spain, ¹⁷Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, ¹⁸Rheumatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, ¹⁹Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ²⁰Clinic pharmacology, Hospital Universitari Bellvitge, Barcelona, Spain, ²¹Servicio de Reumatología. Area Genomica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ²²Arthritis Unit, Rheumatology Dpt, Hospital Clinic of Barcelona, Barcelona, Spain, ²³Clinic pharmacology, Hospital Clinic Barcelona, Barcelona, Spain, ²⁴Clinic pharmacology, Hospital Puerta de Hierro, Madrid, Spain, ²⁵Medicine, Universidad Autonoma Madrid, MADRID, Spain, ²⁶Clinic pharmacology, Parc Tauli Hospital Universitari. I3PT. UAB, Sabadell, Spain, ²⁷Hospital de Mérida, Mérida, Spain, ²⁸Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ²⁹Rheumatology, Parc Tauli Hospital Universitari, Sabadell, Barcelona, Spain
Background/Purpose: Some clinical guidance recommends empirical TNFi dose reductions in AS patients despite lack of robust supportive evidence. Recently, we communicated that a strategy of…
Abstract Number: 2801 • 2017 ACR/ARHP Annual Meeting
Effects of Anti-IL17 Blockade with Secukinumab on Systemic and Local Immune Responses: A Mechanism-of-Action Study in Peripheral Spondyloarthritis
Leonieke van Mens¹, Marleen van de Sande², Silvia Menegatti³, Iris Blijdorp¹, Jet de Jong², Inka Fluri⁴, Talia Latuhihin¹, Arno van Kuijk⁵, Nataliya Yeremenko⁴ and Dominique Baeten¹, ¹AMC, Amsterdam Immunology and Rheumatology Center, Amsterdam, Netherlands, ²Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³Immunology, Immunoregulation Unit, Institut Pasteur, Paris, France, ⁴Amsterdam Immunology and Rheumatology Center, Amsterdam, Netherlands, ⁵Reade, Amsterdam Immunology and Rheumatology Center, Amsterdam, Netherlands
Background/Purpose: IL-17A blockade is an effective therapy for AS and PsA, the prototypical forms of spondyloarthritis(SpA). How IL-17A blockade affects the systemic and local immune…
Abstract Number: 2821 • 2017 ACR/ARHP Annual Meeting
A Multidisciplinary Telemedicine Program for Identification of Spondyloarthritis in Medically Underserviced Communities
Christopher Hawke¹, Laura Passalent¹, Nigil Haroon², Robert D Inman³ and Y. Raja Rampersaud⁴, ¹Allied Health, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ³Department of Immunology, University of Toronto, Toronto, ON, Canada, ⁴Arthritis Program, Krembil Research Institute, University Health Network, Torotno, ON, Canada
Background/Purpose: Early diagnosis is critical for optimal management of patients with inflammatory arthritis. Axial spondyloarthritis (AxSpA) has the longest delay in diagnosis among inflammatory joint…
Abstract Number: 3039 • 2016 ACR/ARHP Annual Meeting
Anti-IL-17A, but Not Anti-TNF, Can Halt Pathological New Bone Formation in Experimental Spondyloarthritis
Melissa van Tok¹, Leonie van Duivenvoorde¹, Ina Kramer², Peter Ingold², Veronique Knaup¹, Joel Taurog³, Frank Kolbinger⁴ and Dominique Baeten⁵, ¹Academic Medical Center, Amsterdam, Netherlands, ²Novartis Institutes for Biomedical Research, Basel, Switzerland, ³Dept Int Med-Rheum Dis Div, University of Texas Southwestern Medical Center, Dallas, TX, ⁴Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland, ⁵Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands
Background/Purpose: Secukinumab, a monocloncal antibody to IL-17A, suppresses signs and symptoms as well as inflammation in ankylosing spondylitis and psoriatic arthritis, and inhibits bone and…
Abstract Number: 711 • 2016 ACR/ARHP Annual Meeting
The Diagnostic Value of the Symptom of Inflammatory Back Pain in the Rheumatology Setting
Denis Poddubnyy¹, Inge Spiller¹, Joachim Listing², Jürgen Braun³, Joachim Sieper¹ and Martin Rudwaleit⁴, ¹Charité Medical University, Berlin, Germany, ²German Rheumatism Research Center, Berlin, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany
Background/Purpose: Inflammatory back pain (IBP) as a symptom has been shown to perform effectively for selecting patients in primary care / orthopaedic settings for referral…

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