ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstracts tagged "SLE"

  • Abstract Number: 647 • 2019 ACR/ARP Annual Meeting

    Is ANA-status at Disease Inception Associated with Long-term Damage Accrual and Direct and Indirect Health Care Costs in the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort?

    May Choi1, Megan Barber 2, Marvin Fritzler 1, John G Hanly 3, Murray Urowitz 4, Yvan St-Pierre 5, Juanita Romero-Diaz 6, Caroline Gordon 7, Sang-Cheol Bae 8, Sasha Bernatsky 9, Daniel J Wallace 10, David A Isenberg 11, Anisur Rahman 12, Ellen M Ginzler 13, Michelle Petri 14, Ian Bruce 15, Paul Fortin 16, Dafna Gladman 17, Jorge Sanchez-Guerrero 18, Rosalind Ramsey-Goldman 19, Munther A Khamashta 20, Cynthia Aranow 21, Meggan Mackay 22, Graciela Alarcón 23, Susan Manzi 24, Ola Nived 25, Andreas Jönsen 25, Asad Zoma 26, Ronald van Vollenhoven 27, Manuel Ramos-Casals 28, Guillermo Ruiz-Irastorza 29, S Sam Lim 30, Kenneth C Kalunian 31, Murat Inanc 32, Diane Kamen 33, Christine Peschken 34, Soren Jacobsen 35, Anca Askanase 36, Vernon Farewell 37 and Ann E Clarke 38, 1Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 2University of Calgary, Calgary, Canada, 3Dalhousie University, Halifax, NS, Canada, 4University Health Network, University of Toronto, Toronto, ON, Canada, 5McGill University Health Centre, Montreal, QC, Canada, 6Instituto Nacional de Ciencias Medicas y Nutricion Salvador, Zubiran Vasco de Quiroga, Mexico City, Mexico, 7University of Birmingham, Birmingham, United Kingdom, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 9Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 10Cedars-Sinai Medical Centre, Beverly Hills, CA, 11Centre for Rheumatology, London, United Kingdom, 12University College London, London, United Kingdom, 13State University of New York Downstate Medical Center, Brooklyn, NY, 14Johns Hopkins University School of Medicine, Baltimore, MD, 15University of Manchester, Manchester, United Kingdom, Manchester, England, United Kingdom, 16Division de Rhumatologie, Département de Médecine, CHU de Québec – Université Laval, Axe maladies infectieuses et inflammatoires, Centre de recherche du CHU de Québec – Université Laval, Canada, Quebec, QC, Canada, 17University of Toronto, Toronto, ON, Canada, 18Toronto Western Hospital, Toronto, ON, Canada, 19Northwestern University, Chicago, IL, 20King's College London School of Medicine, London, United Kingdom, 21Feinstein Institute for Medical Research, Manhasset, NY, 22Feinstein Institute for Medical Research, New York, 23University of Alabama at Birmingham, Birmingham, 24Allegheny Health Network, Pittsburg, PA, 25Lund University, Lund, Sweden, 26Hairmyres Hospital, East Kilbride, United Kingdom, 27Amsterdam Rheumatology and Immunology Center ARC, Amsterdam, the Netherlands, Amsterdam, Netherlands, 28Josep Font Autoimmune Diseases Laboratory, Barcelona, Spain, 29Autoimmune Diseases Unit, Hospital Universitario Cruces, Barakaldo, Spain, Barakaldo, Spain, 30Emory University, Atlanta, GA, 31UC San Diego School of Medicine, LaJolla, CA, 32Istanbul University, Istanbul, Turkey, 33Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA., Charleston, SC, 34University of Manitoba, Winnipeg, Canada, 35Copenhagen Lupus and Vasculitis Clinic, Copenhagen, Denmark, 36Columbia University Medical Center, New York, NY, 37University of Cambridge, Cambridge, United Kingdom, 38University of Calgary, Calgary, AB, Canada

    Background/Purpose: We reported that 7.7% (88/1137) of patients in an international inception cohort were ANA-negative at enrolment (Arthritis Care Res 2018 doi:1002/acr23712).  There are no…
  • Abstract Number: 857 • 2019 ACR/ARP Annual Meeting

    Mesenchymal Stem Cell Therapy Induces FLT3L and CD1c+ Dendritic Cells in Systemic Lupus Erythematosus Patients

    Xinran Yuan 1, Dandan Wang 1 and Lingyun Sun2, 1Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China (People's Republic), 2The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China (People's Republic)

    Background/Purpose: Allogeneic mesenchymal stem cells (MSCs) exhibit immunoregulatory function in human autoimmune diseases such as systemic lupus erythematosus (SLE), but the underlying mechanisms remain incompletely…
  • Abstract Number: 1200 • 2019 ACR/ARP Annual Meeting

    Influenza Vaccination Rates Among Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis on Immunosuppressive Therapy: Findings from a Large Public Hospital

    Judith Aniekwena1, Titilope Olanipekun 2 and Valery Effoe 2, 1Morehouse School of Medicine, Atlanta, GA, 2Morehouse School of Medicine, Atlanta

    Background/Purpose: Influenza infection constitutes a significant cause of morbidity and mortality in patients living with Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA). The risk…
  • Abstract Number: 1787 • 2019 ACR/ARP Annual Meeting

    The Glucocorticoid-Induced Protein GILZ Represent a Checkpoint in the IFN Program in SLE

    Eric Morand1, Champa Nataraja 1, Melissa Northcott 1, Wendy Dankers 1, Jacqueline Flynn 1, Wendy Zhu 1, Taylah Bennett 1, Mehnaz Pervin 1, Brendan Russ 1, James Harris 1 and Sarah Jones 1, 1Monash University, Melbourne, Victoria, Australia

    Background/Purpose: Given the primacy of Type I interferon (IFN) pathways in SLE pathogenesis, and the near-ubiquity of glucocorticoid (GC) use in SLE treatment, clarifying the…
  • Abstract Number: 2540 • 2019 ACR/ARP Annual Meeting

    Impact of IL34, IFN-α and IFN-λ1 on Disease Activity of SLE Patients in Egypt

    Yasmin Hussein1 and Yousra Sadeq 1, 1Mansoura University Hospital, Mansoura, Egypt

    Background/Purpose: SLE is a systemic inflammatory and autoimmune disease. IL-34 plays pivotal roles in the proliferation and differentiation of mononuclear phagocyte cells, osteoclastogenesis and inflammation.…
  • Abstract Number: 649 • 2019 ACR/ARP Annual Meeting

    Potentially Reversible Associations with Fatigue in SLE Patients – Results from a Single-centre Study

    Christina Duesing1, Gamal Chehab 2, Jutta Richter 3, Oliver Sander 4, Rebecca Fischer-Betz 5, Benedikt Ostendorf 1, Hasan Acar 1, Ralph Brinks 6 and Matthias Schneider 5, 1Policlinic of Rheumatology and Hiller Research Unit Rheumatology, Heinrich-Heine-University, Duesseldorf, Germany, Duesseldorf, Nordrhein-Westfalen, Germany, 2Policlinic of Rheumatology and Hiller Research Unit Rheumatology, Heinrich-Heine-University, Duesseldorf, Germany, 3Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, Nordrhein-Westfalen, Germany, 4Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, 5Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany, 6Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany

    Background/Purpose: Fatigue is the most common symptom in SLE patients with a strong impact on patients’ reported quality of life. The cause of fatigue is…
  • Abstract Number: 884 • 2019 ACR/ARP Annual Meeting

    Interferon-Alpha Disrupts Multiple B Cell Tolerance Mechanisms in 3H9 Mice

    Dario Ferri 1, Yuriy Baglaenko 2, Kieran Manion 3, Carolina Munoz-Grajales 4 and Joan Wither5, 1University Health Network, Toronto, ON, Canada, 2Brigham Woman's Hospital, Boston, 3Krembil Research Institute, Toronto, ON, Canada, 4University Health Network, Toronto, Canada, 5University Health Network, Krembil Research Institute, Toronto, ON, Canada

    Background/Purpose: Interferon-alpha (IFNα) is elevated in Systemic Lupus Erythematosus (SLE) and is thought to play a central role in its pathogenesis. Amongst IFNα’s many effects…
  • Abstract Number: 1560 • 2019 ACR/ARP Annual Meeting

    Imbalance Between Th17 and Regulatory T Cells in Patients with Systemic Lupus Erythematosus Combined EBV/CMV Viremia

    Rui Su1, Yue Liu 1, Xinyu Zheng 1, Xiao-feng Li 2 and Cai-hong Wang 3, 1Department of Rheumatology, the Second Hospital of Shanxi Medical University, Taiyuan , Shanxi, China, Tai Yuan, China (People's Republic), 2Department of Rheumatology, the Second Hospital of Shanxi Medical University, Taiyuan , Shanxi, China, TaiYuan, China (People's Republic), 3The Second Hospital of Shanxi Medical University, Tai Yuan, China (People's Republic)

    Background/Purpose: Infection is common and is one of the leading causes of morbidity and mortality in Systemic Lupus Erythematosus (SLE) patients . Excessive using glucocorticoid…
  • Abstract Number: 1829 • 2019 ACR/ARP Annual Meeting

    Ability of Inflammatory and Regulatory Soluble Mediators to Forecast Impending Clinical Disease Flare and Inform a Refined Lupus Flare Prediction Index in a Confirmatory Cohort of SLE Patients

    Melissa E. Munroe1, Sarah Kleckner 1, Wade DeJager 1, Susan R. Macwana 1, Joel Guthridge 2, Eldon Jupe 3, Mohan Purushothaman 3, Sanjiv Sharma 3, Nancy Redinger 1, Teresa Aberle 1, Stan Kamp 1, Cristina Arriens 2, Eliza F. Chakravarty 2, Joan T. Merrill 4 and Judith James 2, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Progentec Diagnostics, Inc., Oklahoma City, OK, 4Okalahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: SLE is marked by altered immune regulation linked to waxing and waning clinical disease activity. This study seeks to verify the alteration of inflammatory…
  • Abstract Number: 2547 • 2019 ACR/ARP Annual Meeting

    Safety Results of 50% Enrollment from a Multicenter, Randomized, Double‑blind, Placebo‑controlled Study to Assess the Efficacy and Safety of Repository Corticotropin Injection in Patients with Systemic Lupus Erythematosus Despite Moderate‑dose Corticosteroid Use

    Anca Askanase1, Dharani Munirathinam 2, Enxu Zhao 2, Julie Zhu 2, Erin Connolly-Strong 2 and Richard Furie 3, 1Columbia University Medical Center, New York, NY, 2Mallinckrodt Pharmaceuticals, ARD, LLC, Bedminster, NJ, 3Northwell Health, Great Neck, NY

    Background/Purpose: Repository corticotropin injection (RCI) is a naturally sourced complex mixture of adrenocorticotropic hormone (ACTH1-39) analogues and other pituitary peptides that stimulates endogenous corticosteroid (CS)…
  • Abstract Number: 658 • 2019 ACR/ARP Annual Meeting

    Disentangling Connective Tissue Diseases: Overlaps and Disparities in Clinical Diagnosis, Classification Criteria and Autoantibodies – Results from the Lupus Extended Autoimmune Phenotype Study

    Sarah Dyball1, John Reynolds 2, Hector Chinoy 2, Tracy Briggs 2, Sahena Haque 3, Eoghan McCarthy 4, Ellen Bruce 5, Ariane Herrick 6, Ian Bruce 7 and Ben Parker 8, 1University of Manchester, Manchestser, United Kingdom, 2University of Manchester, Manchester, United Kingdom, 3University Hospital South Manchester, Manchester, United Kingdom, 4Manchester University NHS FT, Manchester Academic Health Science Centre, Manchester, United Kingdom, Manchester, England, United Kingdom, 5Central Manchester University Hospitals, Manchester, United Kingdom, 6Salford Royal Foundation Trust, Manchester, United Kingdom, 7University of Manchester, Manchester, United Kingdom, Manchester, England, United Kingdom, 8University of Manchester, NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom; Manchester University NHS FT, Manchester Academic Health Science Centre, Manchester, United Kingdom, Manchester, United Kingdom

    Background/Purpose: Connective tissue diseases (CTDs) are a heterogeneous group of diseases with overlapping clinical features and shared immunopathology. In routine practice, a clinician diagnosis is…
  • Abstract Number: 897 • 2019 ACR/ARP Annual Meeting

    Mortality Rates After Coronary Revascularization Procedures Among Systemic Lupus Erythematosus Compared to Diabetes Mellitus and General Population Medicaid Patients

    Medha Barbhaiya1, Sarah Chen 2, Candace Feldman 3, Hongshu Guan 3, Brendan Everett 4 and Karen Costenbader 4, 1Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 2Brigham and Women's Hospital and Harvard Medical School, Boston, 3Brigham and Women's Hospital, Boston, 4Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Despite similar myocardial infarction risks in SLE and diabetes mellitus (DM) patients, individuals with SLE enrolled in Medicaid had substantially higher rates of coronary…
  • Abstract Number: 1571 • 2019 ACR/ARP Annual Meeting

    Validity Evidence Supports the Use of Automated Neuropsychological Assessment Metrics (ANAM) as a Screening Tool for Cognitive Impairment in Patients with Systemic Lupus Erythematosus

    Oshrat Tayer-Shifman1, Robin Green 2, Dorcas Beaton 3, Lesley Ruttan 2, Joan Wither 4, Maria Tartaglia 5, Mahta Kakvan 1, Sabrina Lombardi 2, Nicole Anderson 1, Jiandong Su 1, Dennisse Bonilla 1, Moe Zandy 1, May Choi 6, Marvin Fritzler 6 and Zahi Touma 7, 1University Health Network, University of Toronto, Toronto, ON, Canada, 2University Health Network, Toronto, ON, Canada, 3St. Michael's Hospital, Toronto, ON, Canada, 4University Health Network, Krembil Research Institute, Toronto, ON, Canada, 5University Health Network, University of Toronto, Toronto, ON, Canada, 6Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 7University Health Network, University of Toronto, Toronto, Canada

    Background/Purpose: Cognitive impairment (CI) is highly prevalent in Systemic Lupus Erythematosus (SLE). Screening for CI in SLE may be delayed, if relying on the American…
  • Abstract Number: 1844 • 2019 ACR/ARP Annual Meeting

    The Contribution of Disease Activity, Depression, and Anxiety to Health-Related and Non-Health-Related Quality of Life in US and Filipino Patients with SLE

    Alexandra Watts1, Desiree Azizoddin 2, Shadi Gholizadeh 3, Sarah Mills 4, Geraldine Zamora 5, Daniel Wallace 6, Meenakshi Jolly 7, Michael Weisman 8 and Perry Nicassio 9, 1University of California, Los Angeles, Los Angeles, CA, 2Dana-Farber Cancer Institute, Boston, MA, 3McGill University, Montreal, Canada, 4Lineberger Comprehensive Cancer Center, Chapel Hill, NC, 5Manila Doctors Hospital, Manila, Philippines, 6Cedars-Sinai Medical Center/University California at Los Angeles, Los Angeles, CA, 7Rush University Medical Center, Chicago, IL, 8David Geffen School of Medicine at UCLA, Los Angeles, CA, 9David Geffen School of Medicine, Los Angeles, CA

    Background/Purpose: It is well known that patients with SLE are often afflicted with deficits in quality of life and problems with physical impairment and psychosocial…
  • Abstract Number: 2549 • 2019 ACR/ARP Annual Meeting

    Population Pharmacokinetics of Atacicept in Systemic Lupus Erythematosus (SLE) – an Analysis of Three Clinical Trials

    Maria Pitsui 1, Orestis Papasouliotis2, Colm Farrell 1, Pascal Girard 2, Oezkan Yalkinoglu 3 and Cristina Vazquez-Mateo 4, 1ICON Plc, Dublin, Ireland, 2Merck Institute for Pharmacometrics, Lausanne, Switzerland, 3Merck KGaA, Darmstadt, Germany, 4EMD Serono Research and Development Institute, Inc., Billerica, MA

    Background/Purpose: Atacicept targets the B-cell stimulating factors BLyS and APRIL and has been shown to reduce SLE disease activity. The aim of the analysis was…
  • 1
  • 2
  • 3
  • …
  • 38
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

ACR Pediatric Rheumatology Symposium 2020

© COPYRIGHT 2023 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences