Abstracts tagged "renal disease and systemic lupus erythematosus (SLE)"

Abstract Number: 765 • 2018 ACR/ARHP Annual Meeting
Predictors of End-Stage Renal Disease in Lupus Nephritis
Mery Deeb¹, Konstantinos Tselios², Dafna D Gladman², Jiandong Su² and Murray Urowitz³, ¹Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toront, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: End-stage renal disease (ESRD) is the most important complication of lupus nephritis (LN) and greatly affects mortality. Its incidence has been estimated at 11%…
Abstract Number: 722 • 2018 ACR/ARHP Annual Meeting
Increased Blood Pressure Visit-to-Visit Variability in Patients with Systemic Lupus Erythematosus: Association with Inflammation, Comorbidities and Increased Mortality
Tyler Reese¹, Alyson Dickson¹, Jacquelyn E. Neal², Jocelyn S. Gandelman³, Omair A. Khan², April Barnado⁴, William Dupont², C. Michael Stein¹ and Cecilia P. Chung¹, ¹Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, ³Vanderbilt University School of Medicine, Nashville, TN, ⁴Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Patients with systemic lupus erythematosus (SLE) have increased mortality compared to the general population. As outcomes related to disease control have improved, this mortality…
Abstract Number: 735 • 2018 ACR/ARHP Annual Meeting
Serum Albumin at One Year Predicts Long-Term Renal Outcome
Vinicius Domingues¹, Daniel Goldman², Laurence S Magder³ and Michelle Petri², ¹Medicine, New York University School of Medicine, New York, NY, ²Medicine (Rheumatology), Johns Hopkins University School of Medicine, Baltimore, MD, ³Epidemiology and Public health, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Lupus nephritis remains a major cause of morbidity/mortality in SLE. Our cohort has shown that 20% of SLE patients with lupus nephritis onset…
Abstract Number: 739 • 2018 ACR/ARHP Annual Meeting
Urine and Plasma Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) Differentially Correlates with Renal and Non-Renal Systemic Lupus Erythematosus (SLE): A Prospective, Case-Control Study
Yair Molad^1,2, Mohammad Egbaria³, Ariela Dortort-Lazar^4,5, Elisheva Pokroy-Shapira^3,5, Shirly Oren⁴, Yonatan Edel^3,5 and Vitaly Kliminski^5,6, ¹Rheumatology Unit, Rabin Medical Center - Beilinson Campus, Petah-Tiqva, Israel, ²Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel, ³Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel, ⁴Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petach Tikva, Israel, ⁵Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁶Laboratory of Inflammation Research, Felsenstein Medical Research Center, Rabin Medical Center, Petach Tikva, Israel
Background/Purpose: Elevated levels of sTREM-1 have been previously found in patients with SLE. A prospective, case-control, longitudinal study aimed to assess the value of urinary…
Abstract Number: 763 • 2018 ACR/ARHP Annual Meeting
Comparison of Clinical Characteristics and Outcome between Isolated and Classic Lupus Nephritis
Kubra Bugdayli¹, Cynthia S. Crowson², Ladan Zand³, Mariam P. Alexander⁴, Lynn D. Cornell⁴ and Vaidehi R. Chowdhary⁵, ¹Department of Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, MN, ²Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ⁴Anatomic Pathology, Mayo Clinic College of Medicine and Science, Rochester, MN, ⁵Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN
Comparison of clinical characteristics and outcome between isolated and classic lupus nephritisBackground/Purpose: Lupus nephritis (LN) is a serious manifestation of systemic lupus erythematosus (SLE). Rarely,…
Abstract Number: 665 • 2017 ACR/ARHP Annual Meeting
Low Vitamin D Is Associated with End Stage Renal Disease in Systemic Lupus Erythematosus
Michelle Petri¹, Wei Fu² and Daniel Goldman², ¹Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD, ²Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Vitamin D insufficiency/deficiency is common in SLE. Replacement therapy may help renal disease activity. We asked whether low vitamin D predicted later organ damage.…
Abstract Number: 2621 • 2017 ACR/ARHP Annual Meeting
Minimal Renal Affection in Patients with Systemic LUPUS Erythematosus: Characteristics and Evolution
TC Salman-Monte¹, Eva Rodriguez², José Luis Arevalos³, María José Soler³, Clara Barrios³, Jordi Carbonell⁴ and Julio Pascual³, ¹Rheumatology, Hospital del Mar/Parc de Salut Mar, Barcelona, Spain, ²Nephrology, Hospital del Mar/ Parc de Salut Mar, Barcelona, Spain, ³Nephrology, Hospital del Mar/Parc de Salut Mar, Barcelona, Spain, ⁴Rheumatology Unit, Hospital del Mar/Parc de Salut Mar, Barcelona, Spain
Background/Purpose: Lupus nephritis (LN) is the most common organ involvement in Systemic Lupus Erythematosus (SLE). Indications of renal biopsy (RB) are deterioration of renal function…
Abstract Number: 2622 • 2017 ACR/ARHP Annual Meeting
The Benefit of Vitamin D on SLE Disease Activity Is Largely Explained By Renal Activity
Michelle Petri¹, Daniel Goldman² and Laurence S Magder³, ¹Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD, ²Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Epidemiology and Public health, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Low vitamin D is commonly found in SLE. In previous studies, supplementation of vitamin D resulted in improvement in the Physician Global Assessment and…
Abstract Number: 1181 • 2016 ACR/ARHP Annual Meeting
Risk Factors for Incident Fractures in Patients with Systemic Lupus Erythematosus on Dialysis
Brian Le^1,2, Jennifer Waller³, Reshmitha Radhakrishnan⁴, Sun Jung Oh⁴, Monique Bethel^2,5, Christopher Rice⁴ and Laura Carbone^2,6, ¹Department of Internal Medicine, Augusta University, Augusta, GA, ²Specialty Care, Charlie Norwood VA Medical Center, Augusta, GA, ³Biostatistics, Augusta University, Augusta, GA, ⁴School of Medicine, Augusta University, Augusta, GA, ⁵1120 15th Street, BI 5070, Augusta University, Augusta, GA, ⁶Rheumatology, Augusta University, Augusta, GA
Background/Purpose: Osteoporosis and osteoporotic fractures are significant comorbidities in patients with systemic lupus erythematosus (SLE). Hip fractures are being increasingly recognized as a complication of…
Abstract Number: 2827 • 2016 ACR/ARHP Annual Meeting
Prognostic Significance of Repeat Biopsy in Lupus Nephritis: Histopathologic Worsening Is an Independent Risk Factor for End Stage Renal Disease and Death
Cristina Arriens¹, Sixia Chen², David Karp³, Ramesh Saxena⁴, Kamalanathan Sambandam⁴, Eliza Chakravarty¹, Judith A. James⁵ and Joan T. Merrill⁶, ¹Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ³Internal Medicine/Division of Rheumatic Diseases, University of Texas Southwestern Medical Center, Dallas, TX, ⁴Internal Medicine/Division of Nephrology, University of Texas Southwestern Medical Center, Dallas, TX, ⁵Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Approximately half of SLE patients develop lupus nephritis (LN), a major cause of morbidity and early mortality. It is known that prolonged renal inflammation…
Abstract Number: 2868 • 2016 ACR/ARHP Annual Meeting
NK Cell Characterization in Patients with Systemic Lupus Erythematosus: Increased Frequency of Ki67+ NK Cells Associated with Disease Activity and Type I Interferon Signature
Kelly Hudspeth¹, Shu Wang², Jingya Wang², Saifur Rahman², Michael Smith², Kerry Casey², Geoffrey Stephens³, Miguel Sanjuan², Autoimmunity Molecular Medicine group², Zerai G. Manna⁴, Sarfaraz Hasni⁴, Rachel Ettinger⁵ and Richard Siegel⁶, ¹Immunoregulation Section, Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Respiratory, Inflammation, and Autoimmunity Group, MedImmune LLC, Gaithersburg, MD, ³Respiratory, Inflammatory, and Autoimmune Diseases Research, Medimmune, LLC, Gaithersburg, MD, ⁴National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁵Respiratory, Inflammation and Autoimmunity (RIA), MedImmune, LLC, Gaithersburg, MD, ⁶Immunoregulation Section, Autoimmunity Branch and Office of the Clinical Director National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a complex autoimmune disorder whose pathology appears to involve many immune cell types. While it is clear that autoantibody…
Abstract Number: 1658 • 2014 ACR/ARHP Annual Meeting
Renal Thrombotic Microangiopathy in Systemic Lupus Erythematosus: Novel Risk Factors and Clinical Outcomes
Ana Barrera-Vargas¹, Rodrigo Rosado-Canto², Javier Merayo-Chalico³, Jorge Alcocer-Varela¹ and Diana Gómez-Martín¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Mexico, ³Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Background/Purpose: Thrombotic microangiopathy (TMA) is characterized by microvascular occlusion, systemic or intrarenal platelet aggregation and mechanical injury to erythrocytes. It is a pathological endpoint that…
Abstract Number: 618 • 2013 ACR/ARHP Annual Meeting
Active Renal Disease Is Associated With The Presence Of The Metabolic Syndrome (MetS) In Peruvian Patients With Systemic Lupus Erythematosus (SLE)
Manuel F. Ugarte-Gil^1,2, Rocio V. Gamboa-Cardenas³, Mariela Medina-Chinchon¹, Francisco Zevallos-Miranda¹, Karim E. Diaz-Deza³, J. Mariano Cucho-Venegas¹, Zoila Rodriguez-Bellido^1,4, Jose L. Alfaro-Lozano¹, Risto A. Perich-Campos^1,4, Erika Noriega³, Hugo Torrealva¹ and Cesar A. Pastor-Asurza^1,4, ¹Rheumatology, Hospital Guillermo Almenara, EsSalud, Lima, Peru, ²Universidad Cientifica del Sur, Lima, Peru, ³Rheumatology, Hospital Almenara, Lima, Peru, ⁴Universidad Nacional Mayor de San Marcos, Lima, Peru
Background/Purpose: The MetS prevalence is increased in SLE patients, in particular in those of Hispanic origin and it is associated with a higher risk for…
Abstract Number: 594 • 2013 ACR/ARHP Annual Meeting
Renal Biopsy Findings In Lupus Patient With Insignificant Proteinuria : Relation To Disease Activity and Clinical Manifestations
Abdel Azeim M. Al-Hefny¹, Samah El-bakry², Sameh A. Mobasher³, Ola H. Nada⁴ and Nouran Abaza⁵, ¹Department of Internal Medicine and Rheumatology, Professor of Internal Medicine and Rheumatology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Cairo, Egypt, ²Department of Internal Medicine and Rheumatology, Assistant professor of Internal Medicine and Rheumatology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, ³Department of Internal Medicine and Rheumatology, Lecturer of Internal Medicine and Rheumatology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, ⁴Department of Pathology, Faculty of Medicine, Ain Shams University, Lecturer of Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, ⁵Physical medicine, Rheumatology and Rehabilitation, Lecturer of Physical medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Background/Purpose: Lupus nephritis (LN) remains one of the most serious manifestations of systemic lupus erythematosus (SLE) and is associated with significant morbidity and mortality. Early…
Abstract Number: 2265 • 2012 ACR/ARHP Annual Meeting
Clinical Manifestations of Systemic Lupus Erythematosus Vary Based On Age of Disease Onset
Flora Simmons¹, Natasha M. Ruth², Gary S. Gilkeson³ and Diane L. Kamen⁴, ¹Rheumatology, Medical University of South Carolina, Charleston, SC, ²Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ³Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ⁴Department of Medicine, Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Charleston, SC
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease which disproportionately affects women of child-bearing age. However, onset during childhood and late adult onset can…

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