Abstracts tagged "radiography"

Abstract Number: 111 • 2012 ACR/ARHP Annual Meeting
Ultrasound Measurement of Metacarpal Cartilage Thickness Correlates with Joint Space Narrowing in the Metacarphalangeal Joints of Patients with Rheumatoid Arthritis
Peter Mandl¹, Helga Radner², Gabriela Supp³, Peter V. Balint⁴, Daniel Aletaha³ and Josef S. Smolen⁵, ¹Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Internal Medicine III; Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Rheumatology, National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, ⁵Department of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria
Background/Purpose: To correlate cartilage thickness as measured by ultrasound (US) with joint space narrowing as measured by conventional radiography in the metacarpophalangeal (MCP) joints of…
Abstract Number: L8 • 2012 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Parallel-Group Study of the Safety and Efficacy of Tocilizumab Subcutaneous Versus Placebo in Combination with Traditional Dmards in Patients with Moderate to Severe Rheumatoid Arthritis (BREVACTA)
Alan J. Kivitz¹, Ewa Olech², Michael A. Borofsky³, Beatriz M. Zazueta⁴, Federico Navarro-Sarabia⁵, Lucy Rowell⁶, Clare Nasmyth-Miller⁶ and Janet E. Pope⁷, ¹Altoona Center for Clinical Research, Duncansville, PA, ²Internal Medicine, University of Nevada School of Medicine, Las Vegas, NV, ³Clinical Research Center of Reading, Reading, PA, ⁴Reumatologia, Centro de Investigacion en Enfermedades Reumaticas, Mexicali, Mexico, ⁵Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain, ⁶Roche, Welwyn Garden City, United Kingdom, ⁷Medicine/Rheumatology, St. Joseph Health Care London, University of Western Ontario, London, ON, Canada
Background/Purpose: The intravenous formulation of tocilizumab (TCZ) has demonstrated efficacy with a manageable safety profile in patients (pts) with rheumatoid arthritis (RA) in multiple clinical…
Abstract Number: 455 • 2012 ACR/ARHP Annual Meeting
Lack of Additive Benefits of Concomitant Methotrexate Use to Tocilizumab Monotherapy for Rheumatoid Arthritis in Daily Clinical Practice
Keisuke Izumi¹, Yuko Kaneko², Hidekata Yasuoka³, Noriyuki Seta⁴, Hideto Kameda⁵, Masataka Kuwana⁵ and Tsutomu Takeuchi⁶, ¹Division of Rheumatology, Keio University School of Medicine, Tokyo, Japan, ²Dept of Internal Medicine, Keio Univ School of Medicine, Shinjuku-ku, Japan, ³Division of Rheumatology, Department of Internal Medicine, Keio Univ School of Medicine, Tokyo, Japan, ⁴Department of Internal Medicine, Keio university, Tokyo, Japan, ⁵Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ⁶Keio University School of Medicine, Tokyo, Japan
Background/Purpose: To explore the benefit of concomitant use of methotrexate (MTX) for the effectiveness of TCZ in rheumatoid arthritis (RA) patients in daily clinical practice.…
Abstract Number: 1011 • 2012 ACR/ARHP Annual Meeting
Structural Damage Is Reduced by Early Achievement of Clinical Remission
Paul Emery¹, Vibeke Strand², Andrew S. Koenig³, Ronald Pedersen³ and Eustratios Bananis⁴, ¹Medicine, Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ²Biopharmaceutical Consultant, Portola Valley, CA, ³Specialty Care, Pfizer Inc, Collegeville, PA, ⁴Specialty Care, Pfizer Inc., Collegeville, PA
Background/Purpose: The importance of early, intensive treatment of rheumatoid arthritis (RA) to decrease disease activity and prevent structural damage is established.1 The objective of this…
Abstract Number: 1703 • 2012 ACR/ARHP Annual Meeting
Relationship Between Tobacco Smoking and Radiographic Spinal Progression in Axial Spondyloarthritis: The Role of Inflammatory Activity
Denis Poddubnyy¹, Hildrun Haibel², Joachim Listing³, Elisabeth Märker-Hermann⁴, Henning Zeidler⁵, Jürgen Braun⁶, Martin Rudwaleit⁷ and Joachim Sieper⁸, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, ³German Rheumatism Research Center, Berlin, Germany, ⁴Dr. Horst Schmidt Kliniken, Wiesbaden, Germany, ⁵Medizinische Hochschule, Hannover, Germany, ⁶PsAID taskforce, EULAR, Zurich, Switzerland, ⁷Endokrinologikum Berlin, Berlin, Germany, ⁸Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany
Background/Purpose: Cigarette smoking is associated with functional impairment [1, 2] and radiographic severity of ankylosing spondylitis (AS) [3, 4]. Moreover, smoking status at baseline was…
Abstract Number: 2144 • 2012 ACR/ARHP Annual Meeting
Early RA Patients Fulfilling the New 2010 ACR/EULAR Criteria, Display Better Clinical Responses to DMARD Therapy but Have Higher Radiographic Damage Progression Than Patients with Early RA Not Fulfilling the 2010 ACR/EULAR Criteria
Ruediger Mueller¹, Toni Kaegi¹, Axel Finckh² and Johannes von Kempis¹, ¹Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ²Rheumatology, Geneva University Hospitals, Geneva 14, Switzerland
Background/Purpose: New ACR/EULAR criteria for the classification of rheumatoid arthritis (RA) were recently proposed. The aim of this analysis was to examine the impact of…
Abstract Number: 2670 • 2012 ACR/ARHP Annual Meeting
Genome-Wide Association Study On the Severity of Joint Destruction in Autoantibody Positive Rheumatoid Arthritis Identifies a Role for Sperm Associated Antigen 16
Rachel Knevel¹, Kerstin Klein², Klaartje Somers³, Caroline Ospelt⁴, Jeanine J. Houwing-Duistermaat⁵, Jessica van Nies⁶, Diederik P.C. de Rooy⁶, Laura de Bock⁷, Joris Schonkeren⁸, Gerrie Stoeken-Rijsbergen⁶, Jenna Kiridly⁹, Luis Rodriguez-Rodriguez⁹, Quinta Helmer⁵, Piet Sinissen³, Tom W. J. Huizinga¹, René E.M. Toes¹, Steffen Gay¹⁰, Peter K. Gregersen¹¹, Veerle Somers⁷ and Annette H.M. van der Helm - van Mil⁸, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP),, Zurich, Switzerland, ³Hasselt University, Biomedical Research Institute, Diepenbeek, Belgium, ⁴Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP), Switzerland, Zurich, Switzerland, ⁵Department of Medical Statistics and Bioinformatics, Leiden, Netherlands, ⁶Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁷Hasselt University, Biomedical Research Institute, Belgium, ⁸Leiden University Medical Center, Leiden, Netherlands, ⁹Feinstein Institute for Medical Research and North Shore–Long Island Jewish Health System, Manhasset, New York, ¹⁰Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ¹¹Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: Recent genome-wide association studies (GWAs) have identified >30 SNPs predisposing to Rheumatoid Arthritis (RA). These variants are helpful in unraveling the pathogenesis of RA.…