ACR Meeting Abstracts

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Abstracts tagged "radiography"

  • Abstract Number: 111 • 2012 ACR/ARHP Annual Meeting

    Ultrasound Measurement of Metacarpal Cartilage Thickness Correlates with Joint Space Narrowing in the Metacarphalangeal Joints of Patients with Rheumatoid Arthritis

    Peter Mandl1, Helga Radner2, Gabriela Supp3, Peter V. Balint4, Daniel Aletaha3 and Josef S. Smolen5, 1Rheumatology, Medical University of Vienna, Vienna, Austria, 2Department of Internal Medicine III; Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 4Rheumatology, National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 5Department of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria

    Background/Purpose: To correlate cartilage thickness as measured by ultrasound (US) with joint space narrowing as measured by conventional radiography in the metacarpophalangeal (MCP) joints of…
  • Abstract Number: L8 • 2012 ACR/ARHP Annual Meeting

    A Randomized, Double-Blind, Parallel-Group Study of the Safety and Efficacy of Tocilizumab Subcutaneous Versus Placebo in Combination with Traditional Dmards in Patients with Moderate to Severe Rheumatoid Arthritis (BREVACTA)

    Alan J. Kivitz1, Ewa Olech2, Michael A. Borofsky3, Beatriz M. Zazueta4, Federico Navarro-Sarabia5, Lucy Rowell6, Clare Nasmyth-Miller6 and Janet E. Pope7, 1Altoona Center for Clinical Research, Duncansville, PA, 2Internal Medicine, University of Nevada School of Medicine, Las Vegas, NV, 3Clinical Research Center of Reading, Reading, PA, 4Reumatologia, Centro de Investigacion en Enfermedades Reumaticas, Mexicali, Mexico, 5Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain, 6Roche, Welwyn Garden City, United Kingdom, 7Medicine/Rheumatology, St. Joseph Health Care London, University of Western Ontario, London, ON, Canada

    Background/Purpose: The intravenous formulation of tocilizumab (TCZ) has demonstrated efficacy with a manageable safety profile in patients (pts) with rheumatoid arthritis (RA) in multiple clinical…
  • Abstract Number: 455 • 2012 ACR/ARHP Annual Meeting

    Lack of Additive Benefits of Concomitant Methotrexate Use to Tocilizumab Monotherapy for Rheumatoid Arthritis  in Daily Clinical Practice

    Keisuke Izumi1, Yuko Kaneko2, Hidekata Yasuoka3, Noriyuki Seta4, Hideto Kameda5, Masataka Kuwana5 and Tsutomu Takeuchi6, 1Division of Rheumatology, Keio University School of Medicine, Tokyo, Japan, 2Dept of Internal Medicine, Keio Univ School of Medicine, Shinjuku-ku, Japan, 3Division of Rheumatology, Department of Internal Medicine, Keio Univ School of Medicine, Tokyo, Japan, 4Department of Internal Medicine, Keio university, Tokyo, Japan, 5Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 6Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: To explore the benefit of concomitant use of methotrexate (MTX) for the effectiveness of TCZ in rheumatoid arthritis (RA) patients in daily clinical practice.…
  • Abstract Number: 1011 • 2012 ACR/ARHP Annual Meeting

    Structural Damage Is Reduced by Early Achievement of Clinical Remission

    Paul Emery1, Vibeke Strand2, Andrew S. Koenig3, Ronald Pedersen3 and Eustratios Bananis4, 1Medicine, Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 2Biopharmaceutical Consultant, Portola Valley, CA, 3Specialty Care, Pfizer Inc, Collegeville, PA, 4Specialty Care, Pfizer Inc., Collegeville, PA

    Background/Purpose: The importance of early, intensive treatment of rheumatoid arthritis (RA) to decrease disease activity and prevent structural damage is established.1 The objective of this…
  • Abstract Number: 1703 • 2012 ACR/ARHP Annual Meeting

    Relationship Between Tobacco Smoking and Radiographic Spinal Progression in Axial Spondyloarthritis: The Role of Inflammatory Activity

    Denis Poddubnyy1, Hildrun Haibel2, Joachim Listing3, Elisabeth Märker-Hermann4, Henning Zeidler5, Jürgen Braun6, Martin Rudwaleit7 and Joachim Sieper8, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, 3German Rheumatism Research Center, Berlin, Germany, 4Dr. Horst Schmidt Kliniken, Wiesbaden, Germany, 5Medizinische Hochschule, Hannover, Germany, 6PsAID taskforce, EULAR, Zurich, Switzerland, 7Endokrinologikum Berlin, Berlin, Germany, 8Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany

    Background/Purpose: Cigarette smoking is associated with functional impairment [1, 2] and radiographic severity of ankylosing spondylitis (AS) [3, 4].  Moreover, smoking status at baseline was…
  • Abstract Number: 2144 • 2012 ACR/ARHP Annual Meeting

    Early RA Patients Fulfilling the New 2010 ACR/EULAR Criteria, Display Better Clinical Responses to DMARD Therapy but Have Higher Radiographic Damage Progression Than Patients with Early RA Not Fulfilling the 2010 ACR/EULAR Criteria

    Ruediger Mueller1, Toni Kaegi1, Axel Finckh2 and Johannes von Kempis1, 1Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, 2Rheumatology, Geneva University Hospitals, Geneva 14, Switzerland

    Background/Purpose: New ACR/EULAR criteria for the classification of rheumatoid arthritis (RA) were recently proposed. The aim of this analysis was to examine the impact of…
  • Abstract Number: 2670 • 2012 ACR/ARHP Annual Meeting

    Genome-Wide Association Study On the Severity of Joint Destruction in Autoantibody Positive Rheumatoid Arthritis Identifies a Role for Sperm Associated Antigen 16

    Rachel Knevel1, Kerstin Klein2, Klaartje Somers3, Caroline Ospelt4, Jeanine J. Houwing-Duistermaat5, Jessica van Nies6, Diederik P.C. de Rooy6, Laura de Bock7, Joris Schonkeren8, Gerrie Stoeken-Rijsbergen6, Jenna Kiridly9, Luis Rodriguez-Rodriguez9, Quinta Helmer5, Piet Sinissen3, Tom W. J. Huizinga1, René E.M. Toes1, Steffen Gay10, Peter K. Gregersen11, Veerle Somers7 and Annette H.M. van der Helm - van Mil8, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP),, Zurich, Switzerland, 3Hasselt University, Biomedical Research Institute, Diepenbeek, Belgium, 4Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP), Switzerland, Zurich, Switzerland, 5Department of Medical Statistics and Bioinformatics, Leiden, Netherlands, 6Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 7Hasselt University, Biomedical Research Institute, Belgium, 8Leiden University Medical Center, Leiden, Netherlands, 9Feinstein Institute for Medical Research and North Shore–Long Island Jewish Health System, Manhasset, New York, 10Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, 11Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY

    Background/Purpose: Recent genome-wide association studies (GWAs) have identified >30 SNPs predisposing to Rheumatoid Arthritis (RA). These variants are helpful in unraveling the pathogenesis of RA.…
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