Abstracts tagged "radiography"

Abstract Number: 1262 • ACR Convergence 2022
Clinical and Ultrasound-based Composite Disease Activity Indices and Radiographic Progression in Rheumatoid Arthritis
Irina Gessl¹, Thomas Deimel¹, Paul Studenic¹, Giorgio Tamborrini², Pascal Zufferey³, Daniel Aletaha⁴, Burkhard Moeller⁵ and Peter Mandl¹, ¹Medical University of Vienna, Vienna, Austria, ²Ultrasound Center and Institute for Rheumatology, Zürich, Switzerland, ³HFR, Fribourg, Switzerland, ⁴Medical University Vienna, Wien, Austria, ⁵Inselspital - University Hospital Bern, Bern, Switzerland
Background/Purpose: Musculoskeletal ultrasound (US) has been reported to predict radiographic progression in rheumatoid arthritis (RA). The aim of the study was to test the predictive…
Abstract Number: 1322 • ACR Convergence 2022
Follow up of Incidentally Noted Vertebral Compression Fractures
Jason Yang¹, Alexia Hwang¹, Megan Brochu², Krista Sabina², Meridith Malysz², Bruce Weinstein³ and Jonathan Cheah¹, ¹UMass Chan Medical School, Worcester, MA, ²UMass Memorial Health, Worcester, MA, ³UMass Memorial Health, UMass Chan Medical School, Worcester, MA
Background/Purpose: Vertebral compression fractures (VCFs) in general represent a clinical diagnosis of osteoporosis, predisposing to an increased risk of additional fractures. However, a significant number…
Abstract Number: 1492 • ACR Convergence 2022
Treatment with Non-steroidal Anti-inflammatory Drugs Is Associated with Retardation of Radiographic Spinal Progression in Patients with Axial Spondyloarthritis: 10-year Results from the GErman SPondyloarthritis Inception Cohort
Murat Torgutalp¹, valeria Rios-Rodriguez², Ani Dilbaryan³, Fabian Proft⁴, Mikhail Protopopov⁵, Maryna Verba⁶, Judith Rademacher⁵, Hildrun Haibel¹, Joachim Sieper¹, Martin Rudwaleit⁷ and Denis Poddubnyy⁴, ¹Charité - Universitätsmedizin, Berlin, Berlin, Germany, ²Charité-Universitätsmedizin Berlin, Berlin, Germany, ³Department of Internal Medicine, Moscow City Clinical Hospital, Moscow, Russia, ⁴Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁵Charité Universitätsmedizin Berlin, Berlin, Germany, ⁶Charité-Universitätsmedizin Berlin, corporate member of Freie-Universitat Berlin and Humboldt-Universitat zu Berlin, Department of Gastroenterology, Infectious Diseases and Rheumatology (including Nutrition Medicine), Berlin, Germany, ⁷University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium
Background/Purpose: There are conflicting data regarding the effect of nonsteroidal anti-inflammatory drugs (NSAID) on radiographic spinal progression in axial spondyloarthritis (axSpA). The analysis of the…
Abstract Number: 1902 • ACR Convergence 2022
Structural Severity in Knee Osteoarthritis Impacts Treatment Response: A Post Hoc Pooled Analysis of Lorecivivint Clinical Trials
Yusuf Yazici¹, Christopher Swearingen², Heli Ghandehari³, ismail simsek⁴, Sarah Kennedy⁵, Jeyanesh Tambiah⁶ and Timothy McAlindon⁷, ¹New York University School of Medicine, La Jolla, CA, ²Samumed LLC, San Diego, CA, ³Biosplice Therapeutics, Inc., San Diego, CA, ⁴Alpine Immunesciences, San Diego, CA, ⁵Biosplice Therapeutics, Inc, San Diego, CA, ⁶Biosplice Ther Inc., San Diego, CA, ⁷Tufts Medical Center, Arlington, MA
Background/Purpose: Osteoarthritis (OA) is a leading cause of disability globally, and its disease burden is expected to increase as risk factors such as aging and…
Abstract Number: 1971 • ACR Convergence 2022
Cumulative Joint Inflammation Is Associated with Local Joint Damage Progression in Rheumatoid Arthritis Despite Long-Term Targeted Treatment
Sascha Heckert¹, Sytske Anne Bergstra², Yvonne Goekoop-Ruiterman³, Melek Guler-Yuksel⁴, Willem Lems⁵, Xanthe Matthijssen⁶, Maikel Van Oosterhout⁷, Tom Huizinga⁶ and CF Allaart⁶, ¹Leiden University Medical Centre, Leiden, Netherlands, ²LUMC, Leiden, Netherlands, ³HagaZiekenhuis, The Hague, Netherlands, ⁴Maasstad ziekenhuis, Rotterdam, Netherlands, ⁵Amsterdam University Medical Centers, Amsterdam, Netherlands, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Groene Hart Ziekenhuis, Gouda, Netherlands
Background/Purpose: In Rheumatoid Arthritis (RA), both systemic and local disease activity have been shown to be associated with joint damage progression. Earlier we showed that…
Abstract Number: 2011 • ACR Convergence 2022
More Meticulously Following Treat-to-target in RA Does Not Lead to Less Radiographic Progression: A Longitudinal Analysis in BIODAM
Sofia Ramiro¹, Robert Landewé², Désirée van der Heijde³, Alexandre Sepriano⁴, Oliver FitzGerald⁵, Mikkel Østergaard⁶, Joanne Homik⁷, Ori Elkayam⁸, Carter Thorne⁹, Maggie Larche¹⁰, Gianfranco Ferraccioli¹¹, Marina Backhaus¹², Gilles Boire¹³, Bernard Combe¹⁴, Thierry Schaeverbeke¹⁵, Alain Saraux¹⁶, Maxime Dougados¹⁷, Maurizio Rossini¹⁸, Marcello Govoni¹⁹, Luigi Sinigaglia²⁰, Alain Cantagrel²¹, CF Allaart¹, Cheryl Barnabe²², Clifton O. Bingham III²³, Dirkjan van Schaardenburg²⁴, HIlde Hammer²⁵, Rana Dadashova²⁶, Edna Hutchings²⁶, Joel Paschke²⁶ and Walter P Maksymowych²⁷, ¹Leiden University Medical Center, Leiden, Netherlands, ²Amsterdam University Medical Center, Meerssen, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, ⁴Leiden University Medical Centre, Portela Loures, Portugal, ⁵Conway Institute, University College Dublin, Dublin, Ireland, ⁶Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ⁷Division of Rheumatology, University of Alberta, Edmonton, AB, Canada, ⁸Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁹Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁰McMaster University, Hamilton, ON, Canada, ¹¹Catholic University of the Sacred Heart, Rome, Roma, Italy, ¹²Park-Klinik Weissensee Academic Hospital of the Charité, Berlin, Germany, ¹³Universite de Sherbrooke, Sherbrooke, QC, Canada, ¹⁴CHU Montpellier and Montpellier University, Monpellier, France, ¹⁵FHU ACRONIM, University Hospital of Bordeaux, University of Bordeaux, Bordeaux, France, ¹⁶CHU Brest, Brest, France, ¹⁷Department of Rheumatology, Hôpital Cochin, Paris, France, Paris, France, ¹⁸Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy, ¹⁹S. Anna Hospital and University of Ferrara, Ferrara, Italy, ²⁰Gaetano Pini Institute, Milano, Italy, ²¹CHU Toulouse, Paul Sabatier University, Toulouse, France, ²²University of Calgary, Calgary, AB, Canada, ²³Johns Hopkins University, Baltimore, MD, ²⁴Amsterdam UMC, Amsterdam, Netherlands, ²⁵Diakonhjemmet Hospital, Oslo, Oslo, Norway, ²⁶CARE Arthritis LTD, Edmonton, AB, Canada, ²⁷Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: A Treat-to-Target approach (T2T) is broadly considered to lead to better clinical outcomes and recommended in patients with RA. However, very few studies have…
Abstract Number: 0097 • ACR Convergence 2022
Sex and Race/ethnicity Differences in Knee Symptoms, Function, and Radiographic Features: Preliminary Descriptive Data from the Johnston County Health Study
Luis Palomino¹, Carolina Alvarez², Todd Schwartz³, Yvonne Golightly⁴ and Amanda Nelson², ¹University of North Carolina Chapel hill, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Chapel Hill, NC, ³University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁴University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Osteoarthritis (OA) is the most common form of joint disorder worldwide. Differences in pain, function, and radiographic features in ethnic groups, specifically Hispanics, are…
Abstract Number: 1008 • ACR Convergence 2022
Endothelial Dysfunction in Axial Spondyloarthritis and Its Association with Clinical Disease Characteristics
lourdes Ladehesa-Pineda¹, Clementina Lopez-Medina², Maria Angeles Puche Larrubia³, Raquel Granados⁴ and Eduardo Collantes⁵, ¹Reina Sofia University Hospital/Rheumatology Department/Maimonides Institute for Biomedical Research (IMIBIC), Cordoba, Spain, ²Reina Sofia University Hospital, Rheumatology Department, Jaén, Spain, ³Reina Sofia University Hospital/Rheumatology Department/Maimonides Institute for Biomedical Research (IMIBIC), Granada, Spain, ⁴Reina Sofia University Hospital/Rheumatology Department/Maimonides Institute for Biomedical Research (IMIBIC), Córdoba, Spain, ⁵IMIBIC/University of Cordoba/Reina Sofia Hospital, Cordoba, Spain
Background/Purpose: It has been described an increased presence of cardiovascular risk factors and subclinical atherosclerosis in patients with axial spondyloarthritis (axSpA). Several studies have shown…
Abstract Number: 0182 • ACR Convergence 2021
Tenderness and Radiographic Progression in Rheumatoid Arthritis and Psoriatic Arthritis
Irina Gessl¹, Mihaela Popescu², Gabriela Supp¹, Martina Durechova¹, Michael Zauner¹, Josef Smolen¹, Daniel Aletaha³ and Peter Mandl¹, ¹Medical University of Vienna, Vienna, Austria, ²Maisonneuve Rosemont Hospital, Longueuil, QC, Canada, ³Medical University Vienna, Vienna, Austria
Background/Purpose: In rheumatoid arthritis (RA) and psoriatic arthritis (PsA), swelling is regarded as a sign of synovitis and is associated with radiographic progression. However, recent…
Abstract Number: 0211 • ACR Convergence 2021
Unsupervised Machine-learning Algorithms for the Identification of Clinical Phenotypes in the Osteoarthritis Initiative Database
David Demanse¹, László B. Tankó², Patrick Lustenberger³, Philipp Nikolaus³, Ilja Rasin³, Damian F. Brennan³, Franziska Saxer², Ronenn Roubenoff⁴, Sumehra Premji¹, Philip Conaghan⁵ and Matthias Schieker⁴, ¹Novartis Pharma AG, Basel, Switzerland, ²Novartis Institutes for Biomedical Research, Basel, Switzerland, ³IBM Switzerland AG, Zürich, Switzerland, ⁴Novartis Institutes for Biomedical Research, Basel, Switzerland, Basel, Switzerland, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom
Background/Purpose: Osteoarthritis (OA) is a chronic disabling disease, for which there are only limited treatment options. One major challenge in the development of effective treatment…
Abstract Number: 0214 • ACR Convergence 2021
Baseline Cam or Pincer Morphology Is Associated with Loss of Quantitative Joint Space Width at the Hip: The Johnston County Osteoarthritis Project
Amanda Nelson¹, Carolina Alvarez¹, Yvonne Golightly¹, Jamie Stiller², Jordan Renner¹, Nigel Arden³, Charles Ratzlaff⁴ and Jeffrey Duryea⁵, ¹University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Alamance Regional Medical Center, Durham, NC, ³University of Oxford, Oxford, United Kingdom, ⁴University of British Columbia, Vancouver, BC, Canada, ⁵Brigham and Women's Hospital, Boston, MA
Background/Purpose: To determine the association between radiographic cam and pincer morphology and loss of hip quantitative joint space width (qJSW) in a community-based cohort.Methods: Data…
Abstract Number: 0215 • ACR Convergence 2021
Ultrasonographic Assessment of Knee Osteoarthritis and Its Agreement with Radiography
Khoa Nguyen¹ and Duc Tran², ¹Deparment of Rheumatology, Cho Ray Hospital, Ho Chi Minh City, Vietnam, ²Department of Rheumatology, Cho Ray Hospital, Ho Chi Minh, Vietnam
Background/Purpose: Ultrasonography (US) has been increasingly utilized for the assessment of various musculoskeletal conditions. However, the value of this tool in diagnosis of osteoarthritis (OA)…
Abstract Number: 0218 • ACR Convergence 2021
Synovitis Does Not Mediate the Relationship Between Body Mass Index and Progression of Radiographic Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Marina Bañuls¹, Alecio Lombardi¹, Eric Chang¹, Aladdin H Shadyab¹, Nancy Lane² and Monica Guma³, ¹University of California San Diego, San Diego, CA, ²University of California Davis, Hillsborough, CA, ³University of California San Diego, La Jolla, CA
Background/Purpose: Synovial inflammation is associated with knee osteoarthritis (KOA) progression. Body mass index (BMI) has also been associated with KOA progression. Yet, it is unclear…
Abstract Number: 0451 • ACR Convergence 2021
Tumor Necrosis Factor Inhibitors Show a Delayed Effect on Radiographic Sacroiliitis Progression in Patients with Early Axial Spondyloarthritis: 10-Year Results from the German Spondyloarthritis Inception Cohort
Murat Torgutalp¹, Valeria Rios Rodriguez¹, Maryna Verba², Mikhail Protopopov¹, Fabian Proft¹, Judith Rademacher¹, Hildrun Haibel³, Martin Rudwaleit⁴, Joachim Sieper³ and Denis Poddubnyy⁵, ¹Charité University Medicine Berlin, Berlin, Germany, ²Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Berlin, Germany, ³Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ⁴University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ⁵Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany
Background/Purpose: Observational cohort studies have shown that there is low, but still detectable progression level in radiographic sacroiliitis, which might also have an impact on…
Abstract Number: 0479 • ACR Convergence 2021
A Novel Semi-automated Classifier of Radiographic Hip Osteoarthritis on DXA Scans Is Strongly Predictive of Pain, Clinical Diagnosis and Joint Replacement: Findings from 40,000 Participants in UK Biobank
Benjamin Faber¹, Raja Ebsim², Fiona Saunders³, Monika Frysz¹, Claudia Lindner², Jennifer Gregory³, Richard Aspden³, Nicholas Harvey⁴, George Davey Smith¹, Timothy Cootes² and Jon Tobias¹, ¹University of Bristol, Bristol, United Kingdom, ²University of Manchester, Manchester, United Kingdom, ³University of Aberdeen, Aberdeen, United Kingdom, ⁴University of Southampton, Southampton, United Kingdom
Background/Purpose: Radiographic hip osteoarthritis (rHOA) is traditionally defined on hip or pelvic radiographs, using subjective methods such as Kellgren-Lawrence scoring. Associations between subjective rHOA measures…

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