Abstracts tagged "radiography"

Abstract Number: 2210 • ACR Convergence 2024
Comparison of Dual RF and Anti-CCP Seropositive, Single Seropositive, and Seronegative RA on Radiographic Changes, Flares, and Mortality
Rebecca Brooks¹, Sara Achenbach², Vanessa Kronzer¹, Elena Myasoedova¹, Cynthia Crowson¹ and John Davis¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Rochester, Rochester, MN
Background/Purpose: Both RF and anti-CCP are associated with erosive disease, increased disease activity, and adverse outcomes in RA. However, there have been limited studies investigating how…
Abstract Number: 0235 • ACR Convergence 2024
Spine Structural Lesions in Ankylosing Spondylitis: Comparison Between Radiographic (RASSS) and Opportunistic Thoraco-abdomino-pelvic CT Assessment
Caroline Morizot¹, Inès Favre-Felix², Andréa Mennini³, Elodie Bauer³, Isabelle Chary-Valckenaere⁴ and Damien Loeuille⁵, ¹Nancy University hospital, Nancy, France, ²Nancy university, Vandœuvre-lès-Nancy, France, ³CHRU Nancy, Nancy, France, ⁴Nancy University Hospital, Vandœuvre-lès-Nancy, Lorraine, France, ⁵Phd, Nancy Vandoeuvre, Lorraine, France
Background/Purpose: The aim of this study is to evaluate the prevalence and severity of spinal structural lesions on radiograph versus opportunistic thoraco-abdomino-pelvic CT (TAP CT)…
Abstract Number: 2219 • ACR Convergence 2024
Association of Chondrocalcinosis with Disease Activity and Drug Response in Rheumatoid Arthritis: Baseline Characteristics of the Swiss Rheumatoid Arthritis Outcomes Cohort
Tobias Manigold¹, Nicolas Bodmer², Rosoux Elisabeth³, Deborah Markham⁴, Guillaume Fahrni³, Raphael Micheroli⁵, Lucas Bachmann², Jonas Brändli⁶, Fabio Becce⁷ and Thomas Hügle⁸, ¹Department of Rheumatology, Inselspital University Hospital Bern, Bern, Switzerland., Bern, Switzerland, ²Medignition, Zürich, Switzerland, ³3) Department of Radiology, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland, Lausanne, Switzerland, ⁴Department of Rheumatology, University Hospital Lausanne (CHUV), Switzerland, Lausanne, Switzerland, ⁵University Hospital Zurich, Zurich, Switzerland, ⁶6) Data Science Team, Swiss Clinical Quality Management Foundation, Zurich, Switzerland, Zürich, Switzerland, ⁷Lausanne University Hospital (CHUV), Lausanne, Switzerland, ⁸Lausanne University Hospital, Lausanne, Switzerland
Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) disease can mimic or interfere with the course of rheumatoid arthritis (RA). Previous studies suggest higher prevalence of Chondrocalcinosis…
Abstract Number: 0332 • ACR Convergence 2024
Predictors of Long-term Radiographic Changes in Patients with Idiopathic Inflammatory Myopathies Using Quantitative Imaging Analysis: Real World Experience from a Single Center Longitudinal Cohort
Sangmee Bae¹, Daniela Macrovic², Auguestine Chung², Jessica Channick², Andrea Oh¹, Jennifer Wang¹, Ani Shahbazian², Tiffany De Leon², Yuna Lee², Grace Kim², Donald Tashkin², Jonathan Goldin² and christina Charles-Schoeman³, ¹UCLA, Los Angeles, CA, ²UCLA, Los Angeles, ³UCLA Medical Center, Santa Monica, CA
Background/Purpose: Interstitial lung disease (ILD) is a major cause of mortality in idiopathic inflammatory myopathies (IIM), and high-resolution computed tomography (HRCT) is a key modality…
Abstract Number: 2229 • ACR Convergence 2024
Aptamer Based Proteomic Profiling Demonstrates Significant Differences in Methotrexate Responders versus Non-responders in Newly Diagnosed Rheumatoid Arthritis and Adds Potential Value to Clinical Examination
Kaien Gu¹, Leanne Lac¹, Nathalie Carrier², Liam O'Neil¹, Gilles Boire³, Pingzhou Hu⁴ and Carol Hitchon¹, ¹University of Manitoba, Winnipeg, MB, Canada, ²Universite de Sherbrooke, Sherbrooke, QC, Canada, ³Retired, Sherbrooke, QC, Canada, ⁴Western University, London, ON, Canada
Background/Purpose: Despite methotrexate (MTX) being the cornerstone of rheumatoid arthritis (RA) therapy, uncertainty exists around who will respond to MTX. We aimed to determine the…
Abstract Number: 0411 • ACR Convergence 2024
Axial Radiographic Structural Damage in Enthesitis-Related Arthritis in Children and Young Adult Patients
Annelyse de Araújo Pereira¹, Marcelo Pinheiro², Jade Dib Fernandez¹, Ana Sakamoto³, Adham do Amaral e Castro¹ and Maria Teresa Terreri⁴, ¹UNIFESP-EPM, São Paulo, SP, Brazil, ²UNIFESP/ EPM, São Paulo, SP, Brazil, ³Federal University of São Paulo (UNIFESP), São Paulo, SP, Brazil, ⁴UNIFESP, São Paulo, SP, Brazil
Background/Purpose: Enthesitis-related arthritis (ERA), a distinct subtype of juvenile idiopathic arthritis (JIA) related to HLA-B27 status and peripheral and axial involvement, presents with insidious onset…
Abstract Number: 2353 • ACR Convergence 2024
Effects of Guselkumab on cDAPSA Disease Activity State and Its Association with Long-Term Radiographic Progression in a Cohort of Patients with Moderately-Highly Active Psoriatic Arthritis: Post Hoc Analyses of Phase 3 Randomized Controlled Studies
Philip Mease¹, Alice Gottlieb², Iain McInnes³, Natalie J. Shiff⁴, Toby Thomas⁵, Emmanouil Rampakakis⁶, Francois Nantel⁷, Frederic Lavie⁸ and Proton Rahman⁹, ¹Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, ²Icahn School of Medicine at Mount Sinai, Department of Dermatology, Seattle, WA, ³University of Glasgow, College of Medical Veterinary and Life Sciences, Glasgow, United Kingdom, ⁴Janssen Scientific Affairs, LLC / University of Saskatchewan, Adjunct, Community Health and Epidemiology, Horsham, PA, ⁵Janssen Pharmaceuticals, Horsham, PA, ⁶McGill University, Department of Pediatrics / Scientific Affairs, JSS Medical Research Inc., Montreal, QC, Canada, ⁷Nantel MedSci Consult, Montreal, QC, Canada, ⁸Janssen Cilag Global Medical Affairs, Immunology Global Medical Affairs, Issy les Moulineaux, France, ⁹Memorial University of Newfoundland, Faculty of Medicine, Division of Rheumatology, St. John's, Canada
Background/Purpose: In the Phase 3 DISCOVER (D)-1 and -2 studies, guselkumab (GUS; IL-23p19-subunit inhibitor) 100 mg every 4 weeks (Q4W) or Q8W significantly improved joint…
Abstract Number: 0565 • ACR Convergence 2024
Low Vitamin D Serum Level Is a Risk Factor for Ankylosis in Axial Spondyloarthritis: Evidence from a Nested-Case-Control Study
Anthony Lichaa¹, Pauline KRUG¹ and Adrien Nzeusseu Toukap², ¹Cliniques universitaires St-Luc, Brussel, Belgium, ²Cliniques universitaires Saint-Luc,, St.-Lambrechts-Woluwe, Belgium
Background/Purpose: Axial spondyloarthritis (axSpA) is a progressive disease, characterized by chronic inflammation and progressive structural damage. However, the kinetic of progression to ankylosis and much…
Abstract Number: 0847 • ACR Convergence 2024
Sex and Race-Specific Distributions in Medial Fixed Joint Space Width in Healthy Knees from Three Longitudinal Cohorts
Kent Kwoh¹, Rongrong Tang², Erin Ashbeck³, Edward Bedrick⁴, Yvonne Golightly⁵, Amanda Nelson⁶, Tuhina Neogi⁷, Yong Ge⁸, Zong-Ming Li², Jean Liew⁷, Xiaoxiao Sun⁹, Justin Crawmer¹⁰ and Jeffery Duryea¹¹, ¹University of Arizona, Tucson, AZ, ²University of Arizona Arthritis Center, University of Arizona College of Medicine - Tucson, Tucson, AZ, ³University of Arizona Mel and Enid Zuckerman College of Public Health, Tucson, AZ, ⁴Department of Epidemiology andBiostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, ⁵University of Nebraska Medical Center, Omaha, NE, ⁶University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁷Boston University Chobanian & Avedisian School of Medicine, Boston, MA, ⁸Department of Information Sciences, Eller College of Manangement, University of Arizona, Tucson, AZ, ⁹Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, ¹⁰BWH, Boston, MA, ¹¹Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Quantitative radiographic joint space width (JSW) is often used as ameasure of structural outcomes in randomized controlled trials of knee OA (KOA). How JSW…
Abstract Number: 0868 • ACR Convergence 2024
Autoantibodies to Joint-related Proteins Predict Severe Joint Destruction in Difficult-to-treat Rheumatoid Arthritis Patients
Inger Gjertsson¹, Monica Leu Agelii², Outi Sareila³, Erik Lönnblom⁴, Lennart TH Jacobsson⁵, Lei Cheng⁴, Kristina Forslind⁶, Ingiäld Hafström⁷, Maria Andersson⁸ and Rikard Holmdahl⁹, ¹University of Gothenburg, Gothenburg, Sweden, ²Institutionen för medicin, avd för reumatologi och inflammationsforskning, Goteborg, Sweden, ³Karolinska Institutet, Stockholm, Sweden, ⁴Karolinska Institute, Stockholm, Sweden, ⁵Lund University, Malmö, Sweden, ⁶Lund University, Department of Clinical Sciences Lund, Section of Rheumatology, Lund, Sweden, ⁷Karolinska Institutet, Department of Medicine Huddinge, Division of Gastroenterology and Rheumatology, and Karolinska University Hospital, Stockholm, Sweden, ⁸FoU Spenshult, Halmstad, Sweden, ⁹Department of Rheumatology and Inflammation Research, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Stockholm, Stockholms Lan, Sweden
Background/Purpose: Although treatment of rheumatoid arthritis (RA) has improved there is still a significant number of patients who never reach low disease activity, known as…
Abstract Number: 1190 • ACR Convergence 2024
Cross-sectional Associations Among Sonographic and Radiographic Features and Symptoms Scores in a Population-Based Cohort
Katherine Yates¹, Carolina Alvarez², Sahar Sawani³, Liubov Arbeeva⁴, Todd Schwartz⁵, Serena Savage-Guin⁶, Jordan Renner⁷, Catherine Bakewell⁸, Minna Kohler⁹, Janice Lin¹⁰, Jonathan Samuels¹¹ and Amanda Nelson³, ¹University of North Carolina Medical Center, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Miami, FL, ³University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴University of North Carolina, Chapel Hill, Carrboro, NC, ⁵University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁶Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill,, Chapel Hill, NC, ⁷Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁸Intermountain Healthcare, Salt Lake City, UT, ⁹Massachusetts General Hospital, Boston, MA, ¹⁰Stanford University, Palo Alto, CA, ¹¹NYU Langone, Rye Brook, NY
Background/Purpose: Ultrasound (US) allows for visualization of features of knee osteoarthritis (KOA) including osteophytes, meniscal extrusion, synovitis, and cartilage damage. The current analysis aimed to…
Abstract Number: 1198 • ACR Convergence 2024
Impact of Metabolic Syndrome on Knee Osteoarthritis Severity and Progression: A PROCOAC Cohort Study
Natividad Oreiro¹, Ana Raga², Vanesa Balboa-Barreiro³, Ignacio Rego-Perez⁴, Belen Acasuso⁵, Laura Galindo Domínguez⁶ and francisco J Blanco⁷, ¹CHUAC, La Coruna, Galicia, Spain, ²Grupo de Investigación en Reumatología (GIR). INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC). SERGAS, A Coruña, Spain, ³Unidad de Epidemiología Clínica y Bioeostadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC)., A Coruña, Spain, ⁴Instituto de Investigacion Biomedica de A Coruña-SERGAS, A Coruña, Spain, ⁵Unidad de Investigacion Clinica. Grupo de Investigación de Reumatología (GIR). Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas., Investigation, A Coruña, Spain, A Coruña, Spain, ⁶Instituto de Investigacion Biomedica de A Coruña (INIBIC), A Coruña, Spain, ⁷INIBIC-University of A Coruña, A Coruña, Spain
Background/Purpose: The contribution of metabolic factors to the development of osteoarthritis (OA) has not been fully elucidated. The aim of this study is to analyze…
Abstract Number: L20 • ACR Convergence 2023
Telitacicept, a Human Recombinant Fusion Protein Targeting and Neutralizing B Lymphocyte Stimulator (BlyS) and a Proliferation-Inducing Ligand (APRIL), in Rheumatoid Arthritis (RA) Patients with an Inadequate Response to Methotrexate (MTX): A Randomized, Double-Blind, Phase 3 Study
Li Wang¹, Dong Xu², Jianmin Fang³, Qing Zuraw⁴ and Fengchun Zhang¹, ¹Peking Union Medical College Hospital, Beijing, China, ²Peking Union Medical College Hospital, Dong Cheng District, China, ³RemeGen Co, Ltd., Yantai, China, ⁴RemeGen Biosciences, Inc., San Francisco, CA
Background/Purpose: Telitacicept is a recombinant fusion protein targeting and neutralizing BLyS and APRIL. This phase 3, randomized, double-blind study evaluated the efficacy and safety of…
Abstract Number: 0860 • ACR Convergence 2023
Vagus Nerve Stimulation Enhances Bone Morphology in a Rodent Model of Central Nervous System Inflammation
Chandramohan Natarajan¹, Julia Lucchino¹, David Chenoff² and Yaakov Levine¹, ¹SetPoint Medical, Valencia, CA, ²SetPoint Medical, Sausalito, CA
Background/Purpose: Electrical stimulation of the vagus nerve activates the inflammatory reflex to inhibit cytokines and decrease clinical signs and symptoms of chronic inflammatory disease such…
Abstract Number: 1198 • ACR Convergence 2023
Bicycling Is Not Associated with New Knee Pain or Disease Progression over 48 Months in Those with Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Colin McLaughlin¹, Grace Lo¹, Jeffrey Driban², Timothy McAlindon³, Andrea Kriska⁴, Bonnie Rockette-Wagner⁴, Marc Hochberg⁵, Michael Nevitt⁶, Kent Kwoh⁷ and Charles Eaton⁸, ¹Baylor College of Medicine, Houston, TX, ²Tufts Medical Center, Westborough, MA, ³Tufts Medical Center, Arlington, MA, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵University of Maryland School of Medicine, Baltimore, MD, ⁶University of California San Francisco, Orinda, CA, ⁷University of Arizona, Tucson, AZ, ⁸Brown University, Pawtucket, RI
Background/Purpose: Bicycling is viewed as a non-weight bearing exercise and is often recommended as a preferred exercise for those with knee osteoarthritis (OA).However, there is…

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