ACR Meeting Abstracts

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Abstracts tagged "pulmonary"

  • Abstract Number: L04 • ACR Convergence 2020

    Influenza Adverse Events in Patients with Rheumatoid Arthritis in the Tofacitinib Clinical Program

    Kevin L Winthrop1, Arne Yndestad2, Dan Henrohn3, Hyejin Jo4, Sara Marsal5, Maria Galindo6, Annette Diehl7, Andrea B Shapiro8 and Stanley B Cohen9, 1Oregon Health & Science University, Portland, OR, 2Pfizer Inc, Oslo, Norway, 3Pfizer Inc, Sollentuna, Sweden, 4Syneos Health, Raleigh, NC, 5Vall d’Hebron Hospital, Barcelona, Spain, 6Rheumatology Unit, Hospital Universitario 12 de Octubre, Madrid, Spain, 7Pfizer Inc, Collegeville, PA, 8Pfizer Inc, Peapack, NJ, 9Metroplex Clinical Research Center, Dallas, TX

    Background/Purpose: Patients (pts) with RA have increased susceptibility to seasonal influenza and its complications.1 The COVID-19 pandemic highlights the need to understand acute respiratory RNA…
  • Abstract Number: 1051 • ACR Convergence 2020

    Rituximab for Interstitial Pneumonia with Autoimmune Features at Two Academic Medical Centers

    Kristin D'Silva1, Iazsmin Bauer Ventura2, Marcy Bolster3, Flavia Castelino4, Amita Sharma1, Brent Little1, Ayodeji Adegunsoye2, Mary Strek2, Sydney Montesi1 and Hyon Choi5, 1Massachusetts General Hospital, Boston, MA, 2University of Chicago, Chicago, IL, 3Massachusetts General Hospital, Concord, MA, 4Massachusetts General Hospital/Harvard Medical School, Boston, MA, 5Massachusetts General Hospital, Department of Medicine, Division of Rheumatology, Lexington, MA

    Background/Purpose: Many patients with interstitial lung disease (ILD) have autoimmune features without a distinct rheumatic disease and are thus designated as having interstitial pneumonia with…
  • Abstract Number: 0015 • ACR Convergence 2020

    COVID -19 Lung Inflammation – What Have We Learnt so Far ?

    Sriya Gokaraju1, Maria Darda2, Vinod Vijayaraghavan Nalini Warrier3, Irina Duta3, Fiona Hayes3, Yasser Ahmed4 and Gouri Koduri3, 1Southend University Hospital NHS Trust, Essex, United Kingdom, 2Southend University Hospital NHS Trust, Essex, United Kingdom, 3Southend University Hospital NHS Trust, Essex, United Kingdom, 4Southend University Hospital, Essex, United Kingdom

    Background/Purpose: The SARS CoV-2 pandemic has inspired new interest in understanding the fundamental pathology of pneumonia and Acute Respiratory Distress Syndrome (ARDS). SARS CoV-2 in…
  • Abstract Number: 1052 • ACR Convergence 2020

    Connective Tissue Disease-Related Interstitial Lung Disease in American Indian/Alaska Native People in Alaska

    Joanna Marco1 and Elizabeth Ferucci2, 1University of Washington, Seattle, WA, 2Alaska Native Tribal Health Consortium, Anchorage, AK

    Background/Purpose: Many connective tissue diseases are known to cause interstitial lung disease (ILD). American Indian/Alaska Native (AI/AN) populations have higher prevalence and severity of a…
  • Abstract Number: 0279 • ACR Convergence 2020

    Pulmonary Involvement in a Single Center Cohort of Patients with Systemic Lupus Erythematosus

    Naci Senkal1, Esen Kiyan2, Elif Kocasoy-Orhan3, Ali Demir4, Mehmet Aydogan5, Yasemin Yalcinkaya6, Ahmet Gul6, Murat Inanc7, Mahdume Lale Öcal6 and Bahar Artım-Esen6, 1Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 2Department of Chest Disease, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 3Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 4Fulya Radiologic Imaging Center, İstanbul, Turkey, 5Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 6Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 7Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

    Background/Purpose: The prevalence of SLE pulmonary involvement varies depending on several factors, including diagnostic methods. In this study, we sought to determine the frequency of…
  • Abstract Number: 1200 • ACR Convergence 2020

    Serum Anti-PAD4 and Anti-PAD3/4XR Antibodies in Rheumatoid Arthritis Associated-Interstitial Lung Disease Are Associated with Better Lung Function

    Tim Wilson1, Joshua Solomon2, Jeffrey Swigris2, Erika Darrah3 and M Kristen Demoruelle1, 1University of Colorado, Denver, CO, 2National Jewish Health, Denver, CO, 3Division of Rheumatology, Johns Hopkins University, Baltimore, MD

    Background/Purpose: Rheumatoid arthritis (RA) associated-interstitial lung disease (ILD) affects approximately 10% of RA patients. It is a leading cause of morbidity and mortality, which is…
  • Abstract Number: 0383 • ACR Convergence 2020

    Sex Differences in Severity and Progression of Interstitial Lung Disease in Systemic Sclerosis: What We Have Learned from Clinical Trials

    Elizabeth Volkmann1, Ning Li2, Michael Roth2, Carol Feghali-Bostwick3, Richard Silver4, DeAnna Baker Frost5, Shervin Assassi6, Grace Kim2, Jonathan Goldin2 and Donald Tashkin2, 1University of California, Los Angeles, Los Angeles, CA, 2University of California, Los Angeles, Los Angeles, 3The Medical University of South Carolina, Charleston, SC, 4Medical University of South Carolina, Charleston, 5The Medical University of South Carolina, Charleston, 6University of Texas Houston McGovern Medical School, Division of Rheumatology and Clinical Immunogenetics, Houston, TX

    Background/Purpose: Although systemic sclerosis (SSc) disproportionately affects females compared with males [1], observational studies have demonstrated higher mortality rates in males with SSc [2]. This…
  • Abstract Number: 1244 • ACR Convergence 2020

    Clinical Characteristics and Outcomes in Patients with Primary Sjögren’s Syndrome-Associated Interstitial Lung Disease

    Joanna Marco1, Gregory Gardner1 and Nishant Gupta2, 1University of Washington, Seattle, WA, 2University of Cincinnati, Cincinnati

    Background/Purpose: Primary Sjögren’s syndrome (pSS) is a chronic autoimmune exocrinopathy that features interstitial lung disease (ILD) in up to 16% of patients. The clinical characteristics…
  • Abstract Number: 0387 • ACR Convergence 2020

    Altered Iron Homeostasis and Pulmonary Haemodynamics in Systemic Sclerosis Associated Pulmonary Arterial Hypertension

    Alper Sari1, Christopher Denton2, Svetlana Nihtyanova3, Benjamin Schreiber4 and Voon Ong3, 1Hacettepe University, Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara, Turkey, 2University College London, London, United Kingdom, 3Centre for Rheumatology, Royal Free Campus, UCL Division of Medicine, UK, London, United Kingdom, 4UCL, London, United Kingdom

    Background/Purpose: Iron deficiency (ID) is more frequent in systemic sclerosis (SSc) patients with pulmonary hypertension (PH) than those without and associated with worse prognosis. There…
  • Abstract Number: 1378 • ACR Convergence 2020

    Understanding Diagnostic Pathways in Systemic Sclerosis and Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)

    Shervin Assassi1, Nan Shao2, Ziwei Yin2, Elizabeth Volkmann3, Donald Zoz2 and Thomas Leonard2, 1University of Texas Houston McGovern Medical School, Division of Rheumatology and Clinical Immunogenetics, Houston, TX, 2Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, 3University of California, Los Angeles, Los Angeles, CA

    Background/Purpose: Interstitial lung disease (ILD) is a common manifestation of SSc. SSc-ILD is usually detected in a patient known to have SSc, but ILD may…
  • Abstract Number: 0392 • ACR Convergence 2020

    Prevalence and Survival of Systemic Sclerosis (SSc) and Associated Interstitial Lung Disease (ILD) in Ontario, Canada over 10 Years

    Janet Pope1, Kobina Quansah2, Martin Kolb3, Jason Flavin4, Hassan Shazia5 and Soo Jin Seung5, 1Department of Medicine, University of Western Ontario, St. Joseph's Health Centre, London, ON, Canada, 2Boehringer Ingelheim (Canada) Limited, Burlington, ON, Canada, 3McMaster University and Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamliton, ON, Canada, 4Boehringer Ingelheim, Corporate Headquarters, Burlington, ON, Canada, 5HOPE Research Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

    Background/Purpose: Systemic sclerosis (SSc) is an autoimmune disease characterized by skin thickening, vascular lesions and fibrotic changes in various organs, mainly the lungs, heart, intestinal…
  • Abstract Number: 1381 • ACR Convergence 2020

    Real-World Mono-, Double and Triple Combination Treatment Patterns with Macitentan in Patients with Pulmonary Arterial Hypertension Associated with Connective Tissue Disease (PAH-CTD): Evidence from the Combined OPUS/OrPHeUS Dataset

    Matthew Lammi1, Kelly Chin2, Nick H. Kim3, Vallerie McLaughlin4, Roham Zamanian5, Megan Flynn6, Sandrine Leroy7, Rose Ong7, Graham Wetherill7 and Richard Channick8, 1Lousiana State University Health Sciences Center, New Orleans, LA, 2UT Southwestern Medical Center, Dallas, TX, 3University of California San Diego, La Jolla, CA, 4University of Michigan, Ann Arbor, MI, 5Stanford University School of Medicine, Stanford, CA, 6Actelion Pharmaceuticals US, Inc., South San Francisco, CA, 7Actelion Pharmaceuticals Ltd, Allschwil, Switzerland, 8University of California Los Angeles, Los Angeles

    Background/Purpose: Patients with PAH-CTD have a worse prognosis than patients with most other PAH etiologies. The OPsumit® USers (OPUS) Registry and OPsumit® Historical USers (OrPHeUS)…
  • Abstract Number: 0398 • ACR Convergence 2020

    Chest CT Ordering Practices at Expert Scleroderma Centers in the United States

    Elana Bernstein1, John VanBuren2, Shervin Assassi3, Flavia Castelino4, Lorinda Chung5, Chase Correia6, Luke Evnin7, Tracy Frech8, Emily Startup2, Jessica Gordon9, Faye Hant10, Laura Hummers11, Nora Sandorfi12, Ami Shah13, Victoria Shanmugam14, Virginia Steen15 and Dinesh Khanna16, 1Columbia University, New York, NY, 2University of Utah, Salt Lake City, UT, 3University of Texas Houston McGovern Medical School, Division of Rheumatology and Clinical Immunogenetics, Houston, TX, 4Massachusetts General Hospital/Harvard Medical School, Boston, MA, 5Stanford University School of Medicine and Palo Alto VA Health Care System, Palo Alto, CA, 6Northwestern University, Chicago, IL, 7Scleroderma Research Foundation, Brisbane, CA, 8University of Utah and Salt Lake Veterans Affair Medical Center, Salt Lake City, UT, 9Hospital for Special Surgery, New York, NY, 10Medical University of South Carolina, Charleston, SC, 11Johns Hopkins Univerisity, Ellicott City, MD, 12University of Pennsylvania, Philadelphia, PA, 13Johns Hopkins University School of Medicine, Ellicott City, MD, 14The George Washington University, Washington, DC, 15Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC, 16University of Michigan, Ann Arbor, MI

    Background/Purpose: Interstitial lung disease (ILD) is the leading cause of death in patients with systemic sclerosis (SSc). Although pulmonary function tests (PFTs) are commonly used…
  • Abstract Number: 1430 • ACR Convergence 2020

    The Role of Lung Biopsy in Pediatric ANCA-associated Vasculitis

    Edouard Sayad1, Tiphanie Vogel1, David Moreno McNeill1, Nahir Cortes-Santiago1, David Spielberg1, Kalyani Patel1 and Manuel Silva Carmona1, 1Baylor College of Medicine/Texas Children's Hospital, Houston, TX

    Background/Purpose: Anca-associated vasculitis (AAV) is characterized by vascular inflammation in multiple organs. The diagnosis can be made clinically using a number of different criteria. The…
  • Abstract Number: 0461 • ACR Convergence 2020

    High-Throughput Single-Cell Analysis Reveals Unique Lung Cellular Subsets in a Murine Model of Rheumatoid Arthritis-Inflammatory Lung Disease

    Rohit Gaurav1, Ted Mikuls1, Geoffrey Thiele1, Amy Nelson1, Meng Niu1, Chittibabu Guda1, James Eudy1, Austin Barry1, Debra Romberger1, Michael Duryee1, Bryant England1 and Jill Poole1, 1University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Rheumatoid arthritis (RA)-associated inflammatory lung disease is an extra-articular manifestation of RA associated with increased morbidity and mortality, whose precise molecular mechanisms remain undetermined.…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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