ACR Meeting Abstracts

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Abstracts tagged "Lupus nephritis"

  • Abstract Number: 1648 • 2014 ACR/ARHP Annual Meeting

    Urinary T Cells and Macrophages Strongly Reflect the Disease Activity, Kidney Function, and the Histopathologic Classification in Patients with Lupus Nephritis

    Yoko Wada1, Minoru Sakatsume2, Masaaki Nakano3 and Ichiei Narita1, 1Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, 2Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, 3School of Health Sciences, Faculty of Medicine, Niigata University, Niigata, Japan

    Background/Purpose: Lupus nephritis (LN) is one of the common manifestations of systemic lupus erythematosus (SLE), and the occurrence of LN is considered to be a…
  • Abstract Number: 1635 • 2014 ACR/ARHP Annual Meeting

    Association Between Carrying at Least One Apolipoprotein1 Variant Allele and Hypertension in Lupus Patients with Normal Renal Function

    Ashira Blazer1, H. Michael Belmont2, Robert Clancy3, Peter M. Izmirly4 and Jill P. Buyon5, 1Division of Rheumatology, NYU School of Medicine, New York, NY, 2NYU School of Medicine, New York, NY, 3Rheumatology, NYU Medical Center, New York, NY, 4Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 5Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY

    Background/Purpose The apolipoprotein1 (APOL1) gene encodes a 3 domain protein found both in serum and intracellularly in endothelial cells among other cell types. Variant APOL1…
  • Abstract Number: 589 • 2013 ACR/ARHP Annual Meeting

    A Survey Of Physician and Patient Satisfaction With Control Of Systemic Lupus Erythematosus and Lupus Nephritis

    Neelufar Mozaffarian1, Steve Lobosco2 and Adam Roughley2, 1AbbVie, North Chicago, IL, 2Adelphi Real World Ltd., Macclesfield, United Kingdom

    Background/Purpose: Patient satisfaction with disease control is an important component of overall health and well-being. Current treatment options for systemic lupus erythematosus (SLE) ±lupus nephritis…
  • Abstract Number: 594 • 2013 ACR/ARHP Annual Meeting

    Renal Biopsy Findings In Lupus Patient With Insignificant Proteinuria : Relation To Disease Activity and Clinical Manifestations

    Abdel Azeim M. Al-Hefny1, Samah El-bakry2, Sameh A. Mobasher3, Ola H. Nada4 and Nouran Abaza5, 1Department of Internal Medicine and Rheumatology, Professor of Internal Medicine and Rheumatology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Cairo, Egypt, 2Department of Internal Medicine and Rheumatology, Assistant professor of Internal Medicine and Rheumatology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, 3Department of Internal Medicine and Rheumatology, Lecturer of Internal Medicine and Rheumatology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, 4Department of Pathology, Faculty of Medicine, Ain Shams University, Lecturer of Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, 5Physical medicine, Rheumatology and Rehabilitation, Lecturer of Physical medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Ain Shams University, Cairo, Egypt

    Background/Purpose: Lupus nephritis (LN) remains one of the most serious manifestations of systemic lupus erythematosus (SLE) and is associated with significant morbidity and mortality. Early…
  • Abstract Number: 600 • 2013 ACR/ARHP Annual Meeting

    Factors Associated With Long-Term Renal Function Deterioration In Lupus Nephritis Treated Initially With Combined Prednisolone and Mycophenolate Mofetil (MMF) Or Tacrolimus (Tac)

    Chi Chiu Mok1, Chi Hung To1, King Yee Ying2, Cheuk-Wan Yim3 and Woon Leung Ng4, 1Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, 2Department of Medicine, Princess Margaret Hospital, Hong Kong, Hong Kong, 3Dept of Medicine, United Christian Hospital, Hong Kong, Hong Kong, 4Medicine, United Christian Hospital, Hong Kong, Hong Kong

    Background/Purpose: To study the risk factors for renal function decline in patients with lupus nephritis treated initially with combined steroid and MMF or Tac.Methods: Data…
  • Abstract Number: 580 • 2013 ACR/ARHP Annual Meeting

    Lupus Nephritis Flares Precipitated By Switching From Mycophenolate Mofetil to Azathioprine in Pre-Pregnancy Planning

    Natasha Jordan and David D'Cruz, Louise Coote Lupus Unit, St Thomas' Hospital, London, United Kingdom

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease that affects women of childbearing age. Lupus nephritis is a major cause of morbidity and…
  • Abstract Number: L18 • 2013 ACR/ARHP Annual Meeting

    Long-Term Evaluation of Bone Mineral Density Change in Women Receiving Depot Leuprolide Acetate during Cyclophosphamide Therapy for Severe Lupus Nephritis

    Nathan Meier1 and Mary Anne Dooley2, 1Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Cohort studies demonstrate that 11-83% of female patients receiving cyclophosphamide (CYC) for treatment of severe manifestations of SLE develop premature ovarian failure (POF), dependent…
  • Abstract Number: 2719 • 2013 ACR/ARHP Annual Meeting

    Urinary Angiostatin As Alternative To Biopsy In  lupus Nephritis Patients Among Egyptian

    Shereen Algergawy1, Osama Alshaar2 and Rania Zakaria3, 1rheumatology and rehabilitation, associate prof at benha university faculty of medicine rheumatology and rehabilitation department Egypt, cairo, Egypt, 2clinical pathology, benha university faculty of medicine, benha, Egypt, 3pathology, benha university faculty of medicine, benha, Egypt

    Background/Purpose: Lupus nephritis (LN) is one of the most frequent manifestations of SLE and can be present in 60% of SLE patients.  Kidney biopsy remains…
  • Abstract Number: 2547 • 2013 ACR/ARHP Annual Meeting

    Anti-Ribosomal P Antibody Has a Protective Role In The Development Of Chronic Kidney Disease In Patients With Lupus Nephritis

    Kyung-Eun Lee1, Dong-Jin Park1, Tae-Jong Kim2, Yong-Wook Park1 and Shin-Seok Lee2, 1Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, 2Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea

    Background/Purpose: Anti-ribosomal P antibody (anti-P) in patients with systemic lupus erythematosus (SLE) is associated with neuropsychiatric manifestation. Of interest, recent studies have suggested that anti-P…
  • Abstract Number: 1262 • 2013 ACR/ARHP Annual Meeting

    Comparison Of Remission Rates For Pediatric Membranous Plus Proliferative Lupus Nephritis Versus Isolated Proliferative Lupus Nephritis: An Analysis Of The Childhood Arthritis and Rheumatism Research Alliance Registry

    Alexis Boneparth1, Norman T. Ilowite1 and The CARRA Registry Investigators2, 1Pediatrics, The Children's Hospital at Montefiore, Bronx, NY, 2Duke Clinical Research Institute, Durham, NC

    Background/Purpose: Lupus nephritis (LN) affects many patients with pediatric systemic lupus erythematosus (pSLE) and is a significant cause of disease morbidity. Inability to achieve remission…
  • Abstract Number: 1263 • 2013 ACR/ARHP Annual Meeting

    Childhood-Onset Systemic Lupus Erythematosus In Ontario:  Long Term Outcomes In a Population-Based Cohort With Universal Health Care Coverage

    Deborah M. Levy1, Nadia Gunraj2, Janet E. Pope3, J. Carter Thorne4, Wesley Fidler5, Peter B. Dent6, Johannes Roth7, Roberta A. Berard8, Murray Berall9, Astrid Guttmann10 and Earl D. Silverman11, 1Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 2Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, 3Medicine/Rheumatology, St. Joseph's Health Care, University of Western Ontario, London, ON, Canada, 4Southlake Regional Health Centre, Newmarket, ON, Canada, 5Rheumatology, St. Joseph's Hospital, Thunder Bay, ON, Canada, 6McMaster University, Hamilton, ON, Canada, 7University of Ottawa, Ottawa, ON, Canada, 8Children's Hospital of Western Ontario, London, ON, Canada, 9Nephrology, Humber River Regional Hospital, Toronto, ON, Canada, 10Pediatrics, Institute for Clinical Evaluative Sciences, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 11Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Little is known about the long-term morbidity and mortality of childhood-onset SLE (cSLE) after transition to adult care; however, linking clinical data to administrative…
  • Abstract Number: 645 • 2013 ACR/ARHP Annual Meeting

    Transcript Profiling Of Blood and Kidney Biopsies From Chinese Patients With Lupus Nephritis Reveals Concordant Activation Of Type I IFN Signaling In The Blood and Kidney, Reduced B Cell Presence In The Blood, and Increased Macrophages In The Kidney

    Zheng Liu1, Chris, A. Morehouse1, Xinfang Huang2, Philip Brohawn1, Nan Shen2, Yihong Yao1 and Brandon W. Higgs1, 1Translational Sciences, MedImmune, LLC, Gaithersburg, MD, 2Dept of Rheumatology, Shanghai Ren Ji Hospital, Shanghai, China

    Background/Purpose:  Up-regulated expression of type I interferon-regulated genes has consistently been observed within the peripheral blood in a large proportion of patients with active systemic…
  • Abstract Number: 582 • 2013 ACR/ARHP Annual Meeting

    A Real-World Survey Of Clinical Practice Among Rheumatologists and Nephrologists In The United States Reveals Differences In Care Of Non-Nephritis Systemic Lupus Erythematosus and Lupus Nephritis As Compared With American College Of Rheumatology Treatment Guidelines

    Neelufar Mozaffarian1, Steve Lobosco2 and Adam Roughley2, 1AbbVie, North Chicago, IL, 2Adelphi Real World Ltd., Macclesfield, United Kingdom

    Background/Purpose: Current pharmacotherapy for systemic lupus erythematosus (SLE) and lupus nephritis (LN) includes combinations of nonsteroidal anti–inflammatory drugs (NSAIDs), antimalarials (AMs), glucocorticoids (GCs), and cytotoxic…
  • Abstract Number: 1415 • 2012 ACR/ARHP Annual Meeting

    Effect of Renal Disease On Survival of Patients with Systemic Lupus Erythematosus: A Prospective Cohort Study of 694 Patients

    Chi Chiu Mok1, Raymond Kwok2 and Paul Yip2, 1Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, 2Social Work and Social Administration, University of Hong Kong, Hong Kong, Hong Kong

    Background/Purpose: To study the effect of renal disease on survival and life expectancy of patients with systemic lupus erythematosus (SLE). Methods: Patients who fulfilled >=4…
  • Abstract Number: 1392 • 2012 ACR/ARHP Annual Meeting

    Clinical Correlation with Anti Double Stranded Deoxyribonucleic Acid Via Enzyme Linked Immunoassay Versus Multiplex Immunoassay

    Megan L. Krause1, Melissa R. Snyder2, Cynthia S. Crowson3, Abigail B. Green3 and Kevin G. Moder4, 1Internal Medicine, Mayo Clinic, Rochester, MN, 22Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 3Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 4Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: In systemic lupus erythematosus (SLE), antibodies to double-stranded DNA (dsDNA) are utilized for disease classification and assessment of activity. Enzyme immunoassays (EIAs) and multiplex…
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