Abstracts tagged "Knee"

Abstract Number: 2191 • 2018 ACR/ARHP Annual Meeting
Safety of Ultrasound-Guided Injections Using Local Puncture Site Sterility
Suzan Jaradat¹, Maheswari Muruganandam², Noelle Rolle², Wilmer Sibbitt Jr.³, William Hayward⁴, N. Suzanne Emil³, Monthida Fangtham³, Roderick Fields³ and Arthur Bankhurst³, ¹Internal Medicine, University of New Mexico Health Sciences Center, ALBUQUERQUE, NM, ²University of New Mexico Health Sciences Center, ALBUQUERQUE, NM, ³Rheumatology, University of New Mexico Health Sciences Center, Albuquerque, NM, ⁴The Department of Exercise and Sport Sciences, New Mexico Highlands University, Las Vegas, NM
Background/Purpose: Ultrasound (US)-guided injections in musculoskeletal medicine typically utilize either local puncture site sterility or conventional surgical sterility. We report on the safety and complications…
Abstract Number: 430 • 2018 ACR/ARHP Annual Meeting
Prevalence of Intra-Articular Mineralization on Knee CT in Persons with or at Risk of Knee Osteoarthritis
Tuhina Neogi¹, John A. Lynch², Mohamed Jarraya³, Margaret M. Clancy¹, David T. Felson¹, Michael C. Nevitt⁴, Cora E. Lewis⁵, James Torner⁶ and Ali Guermazi⁷, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²University of California, San Francisco, San Francisco, CA, ³Musculoskeletal Radiology, Boston University School of Medicine, Boston, MA, ⁴Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶University of Iowa, Iowa City, IA, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: While intra-articular (i.a.) mineralization can be visualized on knee radiographs, the sensitivity of its identification is low with this modality, hampering efforts to understand…
Abstract Number: 1161 • 2018 ACR/ARHP Annual Meeting
Association of Knee Ligament and/or Meniscal Injury with Radiographic Knee Osteoarthritis in Military Officers
Yvonne M. Golightly¹, Maryalice Nocera², Anthony I. Beutler³, Jordan B. Renner⁴, Ali Guermazi⁵, John Cantrell², Darin A. Padua², Kenneth L. Cameron⁶, Steven J. Svoboda⁶, Joanne M. Jordan⁷, Richard Loeser⁷, Leigh F. Callahan⁷, Virginia B. Kraus⁸, L. Stefan Lohmander⁹ and Stephen W. Marshall¹, ¹Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Injury Prevention Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Family Medicine, Uniformed Services University, Bethesda, MD, ⁴UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵Boston University School of Medicine, Boston, MA, ⁶Orthopedic Research, Keller Army Community Hospital, Highland Falls, NY, ⁷Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁸Duke Molecular Physiology Institute, Duke University, Durham, NC, ⁹Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: Traumatic knee injuries, such as injuries to the anterior cruciate ligament and menisci, are associated with the early onset and progression of osteoarthritis (OA).…
Abstract Number: 2848 • 2018 ACR/ARHP Annual Meeting
Racial Disparities in Utilization of Knee Replacement: Data from the Osteoarthritis Initiative
Jie Wei^1,2, Chao Zeng^1,3, Uyen-Sa D.T. Nguyen⁴, Hyon K. Choi¹ and Yuqing Zhang⁵, ¹Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ²Department of Health Management Center, Xiangya Hospital, Changsha, China, ³Department of Orthopedics, Xiangya Hospital, Changsha, China, ⁴Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁵Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA
Background/Purpose: While risk of knee osteoarthritis (OA) is higher among black than white individuals, the rate of knee replacement—an effective treatment for end-stage OA among…
Abstract Number: 431 • 2018 ACR/ARHP Annual Meeting
Early Pre-Radiographic Structural Pathology Precedes the Onset of Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Matthew Harkey¹, Julie Davis², Bing Lu³, Lori Lyn Price^4,5, Robert J. Ward⁶, James MacKay⁷, Charles B. Eaton⁸, Grace H. Lo⁹, Mary Barbe¹⁰, Ming Zhang¹¹, Jincheng Pang¹², Alina Stout¹, Timothy E. McAlindon¹³ and Jeffrey B. Driban¹⁴, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Rheumatology, Tufts Medical Center, BOSTON, MA, ³Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁶Radiology, Tufts Medical Center, Boston, MA, ⁷Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁸Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁹Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ¹⁰Temple University School of Medicine, Philadelphia, PA, ¹¹Tufts Medical Center, Boston, MA, ¹²Electrical Engineering, Tufts University, Medford, MA, ¹³Division of Rheumatology, Tufts Medical Center, Boston, MA, ¹⁴Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Individuals that develop accelerated knee osteoarthritis (AKOA) have more frequent knee pain, decreased physical function, and are more likely to receive a knee replacement…
Abstract Number: 1167 • 2018 ACR/ARHP Annual Meeting
The Role of Fear-Avoidance Model on Pain and Disability in Knee Osteoarthritis Patients
Leticia Leon^1,2, Marta Redondo², Sara Lopez de Felipe², Daniel Garriguez³, Lydia A Alcazar⁴ and Luis Rodriguez-Rodriguez⁵, ¹Rheumatology Department, Hospital Clínical San Carlos, and IdISSC, Madrid, Spain, ²Health Sciences, Universidad Camilo Jose Cela, Madrid, Spain, ³Orthopedics Unit, Hospital Clinico San Carlos, Madrid, Spain, ⁴Rheumatology Department and Heath Research Institute (IdISSC), Hospital Clinico San Carlos, Madrid, Spain, ⁵Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain
Background/Purpose: The model of Fear-Avoidance of pain (anxiety, catastrophization and hypervigilance) appears when the pain has maladaptive interpretations, being associated with greater pain and limitations…
Abstract Number: 2909 • 2018 ACR/ARHP Annual Meeting
Diagnostic and Prognostic Value of Ultrasound Compared with Plain Radiography in Knee Osteoarthritis
Annie Yang¹, Fernando Bomfim², Kristen Lee², Mukundan Attur³, Steven B. Abramson⁴ and Jonathan Samuels⁵, ¹Department of Medicine, NYU Langone Health, New York, NY, ²NYU Langone Health, New York, NY, ³Rheumatology, NYU Langone Health, New York, NY, ⁴Dept of Medicine, NYU Langone Health, New York, NY, ⁵Department of Medicine, Divison of Rheumatology, NYU Langone Health, New York, NY
Background/Purpose: Plain radiography of knee osteoarthritis (OA) has inherent diagnostic and prognostic limitations, especially in early disease. Ultrasound (US) examination sheds light on disease activity…
Abstract Number: 432 • 2018 ACR/ARHP Annual Meeting
Relation of Patellofemoral Joint Alignment, Morphology, and Radiographic Osteoarthritis to Frequent Anterior Knee Pain
Erin Macri¹, Tuhina Neogi², Irina Tolstykh³, Cora E. Lewis⁴, James Torner⁵, Michael C. Nevitt⁶ and Joshua J. Stefanik⁷, ¹Physical Therapy, University of Delaware, Newark, DE, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, ⁴University of Alabama Birmingham, Birmingham, AL, ⁵University of Iowa, Iowa City, IA, ⁶Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁷Department of Physical Therapy, University of Delaware, Newark, DE
Background/Purpose: Radiographic patellofemoral osteoarthritis (OA) is prevalent in approximately 25% of population-based samples and 39% of individuals with knee pain. Discordance between knee OA features…
Abstract Number: 1169 • 2018 ACR/ARHP Annual Meeting
Association between Depressive Symptom Subtypes and Disease Severity in Knee Osteoarthritis
Alan Rathbun¹, Megan Schuler², Elizabeth Stuart³, Michelle Shardell⁴, Michelle S. Yau⁵, Joseph Gallo⁶ and Marc C. Hochberg⁷, ¹Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, ²Rand Coportation, Boston, MA, ³Mental Health, Biostatistics, and Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, ⁵Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, ⁶Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁷University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Latent and modifiable factors, such as depressive symptoms, may affect the course of knee OA. Depression is clinically heterogeneous, and effects on pain and…
Abstract Number: 1L • 2017 ACR/ARHP Annual Meeting
Efficacy and Safety of Intra-Articular Sprifermin in Symptomatic Radiographic Knee Osteoarthritis: Results of the 2-Year Primary Analysis from a 5-Year Randomised, Placebo-Controlled, Phase II Study
Marc C. Hochberg¹, Ali Guermazi², Hans Guehring³, Aida Aydemir⁴, Stephen Wax⁵, Patricia Fleuranceau-Morel⁴, Asger Reinstrup Bihlet⁶, Inger Byrjalsen⁶, Jeppe Ragnar Andersen⁶ and Felix Eckstein⁷, ¹University of Maryland School of Medicine, Baltimore, MD, ²Boston Imaging Core Lab, LLC, and Boston University School of Medicine, Boston, MA, ³Merck KGaA, Darmstadt, Germany, ⁴EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, ⁵EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), BIllerica, MA, ⁶Nordic Bioscience, Herlev, Denmark, ⁷Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria

Background/Purpose: Sprifermin, a novel recombinant human fibroblast growth factor-18 is currently investigated as a potential disease-modifying osteoarthritis (OA) drug. Two-year primary data from a 5-year…
Abstract Number: 13L • 2017 ACR/ARHP Annual Meeting
Significant, Sustained Improvement in Knee Function after Intra-Articular TPX-100: A Double-Blind, Randomized, Multi-Center, Placebo-Controlled Phase 2 Trial
Dawn McGuire¹, Nancy E Lane², Neil Segal³, Samy Metyas⁴, Hans Richard Barthel⁵, Meghan Miller¹, David Rosen¹ and Yoshi Kumagai¹, ¹OrthoTrophix, Inc, Oakland, CA, ²UC Davis Medical Center, Sacramento, CA, ³University of Kansas, Shawnee, KS, ⁴Medvin Clinical Research, Covina, CA, ⁵Barthel Clinic, Santa Barbara, CA

Background/Purpose: The current Phase 2 study was designed to evaluate safety, tolerability and preliminary efficacy of TPX-100 by IA administration in subjects with mild to…
Abstract Number: 1029 • 2017 ACR/ARHP Annual Meeting
What to Measure after Arthroplasty? Confirmation of a Core Domain Set
Anh Hoang¹, Susan M. Goodman², Mark P. Figgie³, Mathias Bostrom⁴, Douglas Padgett⁴, Lisa A. Mandl^5,6,7, Peter Sculco⁸, Alexander McLawhorn⁹ and Jasvinder A. Singh¹⁰, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Medicine, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ³Orthopaedic Surgery, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁴Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, ⁵Department of Medicine, Hospital for Special Surgery, New York, NY, ⁶Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁷Department of Rheumatology, Hospital for Special Surgery, New York, NY, ⁸Orthopaedic Surgery, Hospital for Special Surgey, New York, NY, ⁹Hospital for Special Surgey, New York, NY, ¹⁰Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The Outcomes Measures in Rheumatology Trials (OMERACT) TJR Working Group has proposed six core domains that would constitute a standardized measurement set that can…
Abstract Number: 2019 • 2017 ACR/ARHP Annual Meeting
Structural Abnormalities in the Knee Detected By MRI in Middle-Aged Subjects without Radiographic Knee Osteoarthritis
Jaanika Kumm¹, Aleksandra Turkiewicz², Fan Zhang² and Martin Englund², ¹Department of Radiology, University of Tartu, Tartu, Estonia, ²Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit, Lund University, Lund, Sweden
Background/Purpose: Early OA is a complex, poorly understood and still largely an unchartered “entity”. Thus, our purpose was evaluate the prevalence of findings suggestive of…
Abstract Number: 2835 • 2017 ACR/ARHP Annual Meeting
5-Year Evolution Patterns of Physical Activity and Sedentary Behavior of Patients with Symptomatic Hip and/or Knee Osteoarthritis, and Their Sociodemographic and Clinical Correlates
Sarah Bitar¹, Abdou Y Omourou^2,3, Aurélie Van-hoye¹, Francis Guillemin^4,5 and Anne-Christine Rat^4,5,6, ¹Université de Lorraine, EA 4360 APEMAC, Nancy, France, ²Université de lorraine, EA 4360 APEMAC, Nancy, France, ³Inserm, CIC-1433 Clinical epidemiology, Nancy, France, ⁴Université de Lorraine, EA4360, APEMAC, Nancy, France, ⁵Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ⁶Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: Regular Physical Activity (PA) at a moderate level of intensity for approximately 2.5 hours per week is recommended in the management of hip and/or…
Abstract Number: 1043 • 2017 ACR/ARHP Annual Meeting
Comparison of the Costs for Hyaluronic Acid and Total Knee Arthroplasty in the Treatment of OA for the Blue Cross/Blue Shield Patient Population
Kevin Ong¹, Faizan Niazi², Edmund Lau³, Peter Shaw² and Steven Kurtz¹, ¹Exponent, Inc., Philadelphia, PA, ²Ferring Pharmaceuticals, Inc., Parsippany, NJ, ³Exponent, Inc., Menlo Park, CA
Background/Purpose: Previous HA studies have focused on the Medicare population, but less is known of the treatment patterns and cost of HA relative to knee…

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