Abstracts tagged "Knee"

Abstract Number: 73 • 2013 ACR/ARHP Annual Meeting
Fibrillin-1 Expression and Function Is Needed For Normal Joint Function and Mutations Leads To Osteoarthritis
Wasabha Ramanayake¹, Helen Jones¹, Isabel Orriss², Tim Arnett², Andrew Pitsillides³, Christopher P. Denton⁴, David J. Abraham⁴ and Blandine Poulet⁵, ¹Centre for Rheumatology and Connective tissue diseases, UCL Medical School, London, United Kingdom, ²Department of Cell and developmental biology, University College London, London, United Kingdom, ³Department of Comparative Biomedical Sciences, Royal Veterniary College, London, United Kingdom, ⁴Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, London, United Kingdom, ⁵Centre for Rheumarology and connective tissue diseases, UCL Medical School, London, United Kingdom
Background/Purpose: Osteoarthritis (OA) is a common degenerative disease leading to pain and disability in >6million british people. The TGFb signalling pathway has been shown to…
Abstract Number: 2130 • 2013 ACR/ARHP Annual Meeting
Factors Associated With Two-Year Pain Experience Outcome In Knee Osteoarthritis
Jamie E. Rayahin¹, Joan S. Chmiel², Orit Almagor², Laura Belisle², Alison H. Chang³, Kirsten Moisio², Karen W. Hayes², Yunhui Zhang² and Leena Sharma², ¹University of Illinois, Chicago, Chicago, IL, ²Northwestern University, Chicago, IL, ³Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL
Background/Purpose: Few strategies to improve pain outcome in knee OA exist, in part because methods to evaluate this outcome are not established. ICOAP development…
Abstract Number: 993 • 2013 ACR/ARHP Annual Meeting
An Analysis Of Healthcare Resource Utilization Among Patients Undergoing Total Knee Arthroplasty In The United Kingdom
Mireia Raluy¹, Michael Schoenfeld², Dimitra Lambrelli¹, Meng Wang³, Ning Wu⁴, Shih-Yin Chen⁴ and Russel Burge², ¹Health Economics, United BioSource Corporation, London, United Kingdom, ²Global Health Outcomes, Eli Lilly and Company, Indianapolis, IN, ³Economic Analysis and Solutions, United BioSource Corporation, London, United Kingdom, ⁴Economic Analysis and Solutions, United BioSource Corporation, Lexington, MA
Background/Purpose: Elective total knee arthroplasty (eTkA) is among the most commonly performed surgical procedures. The typical reasons for eTkA are pain and decreased quality of…
Abstract Number: 2855 • 2013 ACR/ARHP Annual Meeting
Association Of Back Pain With Functional Limitations In Patients With Knee and Hip Osteoarthritis
Adam P. Goode¹, Hayden B. Bosworth², Cynthia Coffman², Amy Jeffreys³, Eugene Z. Oddone³, William S. Yancy Jr.⁴ and Kelli D. Allen³, ¹Community and Family Medicine, Duke University, Durham, NC, ²Health Services Research, Durham VA Medical Center and Duke University Medical Center, Durham, NC, ³Health Services Research, Duke and Durham VA Medical Center, Durham, NC, ⁴Health Services Research, Durham VA Medical Center, Durham, NC
Background/Purpose: Back pain, most commonly occurring in the lower back, is a prevalent condition and common reason for both decreased function and quality of life.…
Abstract Number: 2131 • 2013 ACR/ARHP Annual Meeting
Osteoarthritis Pain: Variability and Clinical Correlations
Thomas J. Schnitzer¹, Renita Yeasted², Leijan Huang³, Jennifer Duffecy⁴, Mark Begale⁴ and A. Vania Apkarian³, ¹PM&R and Int Med, Northwestern University, Chicago, IL, ²PM&R, Northwestern University, Chicago, IL, ³Physiology, Northwestern University, Chicago, IL, ⁴Preventive Medicine, Northwestern University, Chicago, IL
Background/Purpose: Although osteoarthritis (OA) is an intensely studied model of chronic pain, little is known about the temporal dynamics of OA pain intensity and how…
Abstract Number: 859 • 2013 ACR/ARHP Annual Meeting
Knee Effusion: Sensitivity and Specificity Of Ultrasound For The Identification Of Calcium Pyrophosphate Crystals
Erika Catay¹, Santiago Ruta², Javier Rosa¹, David A. Navarta³, Marina Scolnik⁴, Ricardo Garcia-Monaco⁵ and Enrique R. Soriano⁶, ¹Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina
Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) is an important cause of arthritis mainly in elderly people. The final diagnosis is based on the identification of…
Abstract Number: 2756 • 2013 ACR/ARHP Annual Meeting
Serum Periostin Is Associated With Prevalent Knee Osteoarthritis and Predicts Disease Progression In Women: The Ofely Study
Jean-Charles Rousseau¹, Elisabeth Sornay-Rendu¹, Cindy Bertholon¹, Patrick Garnero² and Roland Chapurlat³, ¹INSERM UMR 1033, Lyon, France, ²INSERM, UMR 1033, Lyon and Cisbio Bioassays, Bagnols/Cèze, France, ³Service de Rhumatologie et Pathologie Osseuse, INSERM UMR 1033 and Université de Lyon, Hôpital Edouard Herriot, Lyon, France
Background/Purpose: Periostin (POSTN) is a secreted vitamin K-dependent (Gla-containing) protein produced by osteoblasts and chondrocytes. The aim of this study was to investigate the relationships…
Abstract Number: 2134 • 2013 ACR/ARHP Annual Meeting
Responsiveness and Predictive Ability Of The Knee Society Scale (KSS) Score
Jasvinder A. Singh^1,2, Cathy Schleck³, W. Scott Harmsen⁴ and David Lewallen⁵, ¹Rheumatology, Birmingham VA, Birmingham, AL, ²Department of Medicine, University of Alabama, Tuscaloosa, AL, ³Mayo Clinic College of Medicine, Rochester, MN, ⁴Mayo Clinic, Rochester, MN, ⁵Orthopedics, Mayo Clinic college of medicine, Rochester, MN
Background/Purpose: The KSS questionnaire has previously been shown to have face, content and construct validity and test-retest reliability. Our objective was to assess the Responsiveness and Predictive…
Abstract Number: 829 • 2013 ACR/ARHP Annual Meeting
Is The Severity Of Knee Osteoarthritis On MRI Associated With Outcome Of Exercise Therapy?
Jesper Knoop¹, Joost Dekker², Marike van der Leeden^3,4, Martin van der Esch⁴, J.P. Klein⁵, David J. Hunter⁶, Leo D. Roorda⁴, Martijn P.M. Steultjens⁷ and Willem F. Lems⁸, ¹Amsterdam Rehabilitation Research Center, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ²Rehabilitation Medicine, Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, ³Rehabilitation Medicine/EMGO, VU University Medical Center, Amsterdam, Netherlands, ⁴Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁵Radiology, VU University Medical Center, Amsterdam, Netherlands, ⁶Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁷Institute for Applied Health Research and School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland, ⁸Rheumatology, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: To evaluate associations between severity of knee osteoarthritis (OA) on MRI and treatment outcome in knee OA patients treated with exercise therapy. Methods: Ninety-five…
Abstract Number: 2752 • 2013 ACR/ARHP Annual Meeting
Good, Moderate and Poor Outcome Trajectories Of Pain Severity In Early Symptomatic Knee Osteoarthritis; 5 Year Follow-Up Of Check study
Janet Wesseling¹, Alex N. Bastick², Sita M.A. Bierma-Zeinstra³ and Johannes W.J. Bijlsma⁴, ¹Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ²General Practice, Erasmus MC - University Medical Center, Rotterdam, Netherlands, ³Orthopaedics and General Practice, Erasmus MC - University Medical Center, Rotterdam, Netherlands, ⁴Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: Knee pain is often the first sign of knee OA (osteoarthritis) and it is known that its course can be very different between patients over…
Abstract Number: 2140 • 2013 ACR/ARHP Annual Meeting
Effects Of Intra-Articular Hyaluronic Acid Injections On Gait Pattern In Patients With Knee Osteoarthritis
Bilal Uysal¹, Aysegul Ketenci², Sina Esmaeilzadeh² and Dilsad Sindel², ¹Physical Medicine And Rehabilitation, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ²Physical Medicine and Rehabilitation, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey
Background/Purpose: The aim of this study was to determine the effects of intra-articular hyaluronic acid (HA) injections on gait pattern of both injected and un-injected…
Abstract Number: 264 • 2013 ACR/ARHP Annual Meeting
The Proportion Of Knee Osteoarthritis Patients In Southern Sweden That Seek Medical Car
Aleksandra Turkiewicz¹, Maria Gerhardsson de Verdier², Gunnar Engström³, Stefan Lohmander¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Astra Zeneca R&D Molndal, Molndal, Sweden, Molndal, Sweden, ³Dept of Cardiovascular epidemiology, Clinical Sciences, Lund University, Lund, Sweden
Background/Purpose: To provide estimates of the proportion of subjects with knee osteoarthritis (OA) that seek healthcare for knee OA or joint pain within an 8-year…
Abstract Number: 2753 • 2013 ACR/ARHP Annual Meeting
Relationship Of Pre-Radiographic MRI Lesions With Prevalent Frequent Knee Symptoms and Incident Persistent Knee Symptoms In Persons At Higher Risk For Knee Osteoarthritis
Leena Sharma¹, Joan S. Chmiel¹, Orit Almagor¹, Dorothy D. Dunlop², Marc C. Hochberg³, Charles Eaton⁴, C. Kent Kwoh⁵, Rebecca D. Jackson⁶, Joan M. Bathon⁷, Ali Guermazi⁸, Frank Roemer⁹, Michel Crema⁸, W. Jerry Mysiw⁶ and Michael C. Nevitt¹⁰, ¹Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Medicine, University of Maryland School of Medicine, Baltimore, MD, ⁴Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, ⁵School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁶Ohio State University, Columbus, OH, ⁷Columbia University, New York, NY, ⁸Boston University, Boston, MA, ⁹Klinikum Augsburg, Augsburg, Germany, ¹⁰Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA
Background/Purpose: The clinical significance of pre-radiographic MRI lesions in persons at risk for knee OA is unclear. Understanding whether such lesions are inconsequential or early…
Abstract Number: 2146 • 2013 ACR/ARHP Annual Meeting
Effects Of Chondroitin Sulfate On Brain Response To Painful Stimulation In Knee Osteoarthritis Patients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Jordi Monfort¹, Jesús Pujol², O Contreras-Rodriguez², Jone Llorente-Onaindia², M López-Solà², Laura Blanco-Hinojo², J Deus², H Ortiz², Francisco Montañés³, M Campillo², Pere Benito², Laura Sánchez⁴, Marta Herrero⁵ and Josep Vergés⁶, ¹Reumatologia, Hospital del Mar, Barcelona, Spain, ²Hospital del Mar, Barcelona, Spain, ³Rhaumatology, Hospital del Mar, Barcelona, Spain, ⁴Bioiberica, Barcelona, Spain, ⁵Pharmascience Division, Bioiberica S.A., Barcelona, Spain, ⁶Pre-Clinical R&D Area, Pharmascience Division, BIOIBERICA S.A., Barcelona, Spain
Background/Purpose: Knee osteoarthritis (OA) is a degenerative joint disease causing symptoms in 12% of people over the age of 65 . A variety of treatments…
Abstract Number: 265 • 2013 ACR/ARHP Annual Meeting
All-Cause Mortality and Incident Cardiovascular Disease In Knee Osteoarthritis: The Framingham Study
Devyani Misra¹, David T. Felson², Ida K. Haugen³, Martin Englund⁴ and Tuhina Neogi¹, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: Studies examining the relation of osteoarthritis (OA) to mortality or cardiovascular disease (CVD) have reported conflicting results, raising the question of whether OA itself…

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