Abstracts tagged "Knee"

Abstract Number: 2507 • 2013 ACR/ARHP Annual Meeting
What Is The Risk Of Having a Total Hip Or Knee Replacement for Patients With Lupus?
Sandeep Mukherjee¹, David Culliford², Nigel K. Arden³ and Christopher J. Edwards¹, ¹NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom, ²Faculty of Medicine, University of Southampton, Southampton, United Kingdom, ³NDORMS; MRC Lifecourse Epidemiology Unit, Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom
Background/Purpose: Individuals with systemic lupus erythematosus (SLE) frequently have arthralgia, but joint damage leading to surgery is thought to be less common. In addition to…
Abstract Number: 1694 • 2013 ACR/ARHP Annual Meeting
A Randomised Trial Of A Brace For Patellofemoral Osteoarthritis Targeting Knee Pain and Bone Marrow Lesions
David T. Felson^1,2, Matthew J. Parkes¹, Andrew D. Gait³, Elizabeth J. Marjanovic³, Mark Lunt⁴, Charles E. Hutchinson⁵, Laura Forsythe⁶, Timothy F. Cootes³ and Michael Callaghan¹, ¹Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Imaging Sciences, School of Cancer & Enabling Sciences, University of Manchester, Manchester, United Kingdom, ⁴Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom, ⁵Warwick Medical School, University of Warwick, Coventry, United Kingdom, ⁶Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom
Background/Purpose: Patellofemoral (PF) braces have been shown to increase contract area in this joint, decreasing focal stress and may also correct patellar malalignment. Bone marrow…
Abstract Number: 237 • 2013 ACR/ARHP Annual Meeting
The Association Of Radiographic Disease With Lesions On MRI In Lateral Compartment Knee Osteoarthritis: The Osteoathritis Initiative
Barton L. Wise¹, Jingbo Niu², Felix Liu³, John A. Lynch⁴, Yuqing Zhang⁵, Ali Guermazi⁶, David T. Felson⁵, C. Kent Kwoh⁷ and Nancy E. Lane¹, ¹Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³University of California at San Francisco, San Francisco, CA, ⁴Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, ⁵Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁶Boston University, Boston, MA, ⁷School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Lateral compartment knee tibio-femoral radiographic osteoarthritis (ROA) is associated with pain and disability, and the epidemiology of this form of knee OA is…
Abstract Number: 2151 • 2013 ACR/ARHP Annual Meeting
Synergistic Effect of Combining BioniCare® in an Unloading Brace for Osteoarthritis of the Knee
Thomas Zizic¹, David S. Hungerford², Edmund J. MacLaughlin³, Craig Mines⁴, Shaili Deveshwar⁵, Theresa Lawrence Ford⁶, Cynthia Elliott⁶, John R. Principe⁷, Jack S. Tuber⁸ and Joy Schechtman⁹, ¹Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Ortho Surgery, Johns Hopkins University, Baltimore, MD, ³The Johns Hopkins University School of Medicine, Cambridge, MD, ⁴East Side OrthoCare, Snellville, GA, ⁵Sports Medicine and Orthopedic Center, Greensboro, NC, ⁶North Georgia Rheumatology, Lawrenceville, GA, ⁷WellBeingMD, Palos Heights, IL, ⁸The Johns Hopkins University, Baltimore, Maryland, Baltimore, MD, ⁹SunValley Arthritis Center, Peoria, AZ
Background/Purpose: The purpose of this study was to see if incorporating the BioniCare device into an unloading brace would produce more rapid improvement, greater compliance…
Abstract Number: 1134 • 2013 ACR/ARHP Annual Meeting
More Evidence For Breaking The ‘law Of valgus’: Imaging Evidence For Higher Prevalence and Volume Of Bone Marrow Lesions In The Medial Patellofemoral Joint
Charles Ratzlaff¹ and Jeffrey W. Duryea², ¹Harvard Medical School / Brigham and Women's Hospital, Boston, MA, ²Radiology, Brigham and Women's Hospital, Boston, MA
Background/Purpose : We recently developed an efficient semi-automated measure of tibial and femoral BML volume and validated it against the Whole-Organ Magnetic Resonance Imaging Score…
Abstract Number: 238 • 2013 ACR/ARHP Annual Meeting
Structural Predictors Of Ten Year Knee Cartilage Volume Loss
Dawn Aitken¹, Hussain Ijaz Khan¹, Changhai Ding², Leigh Blizzard³, Jean-Pierre Pelletier⁴, Johanne Martel-Pelletier⁴, Flavia Cicuttini⁵ and Graeme Jones², ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁴Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁵Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia
Background/Purpose: Cartilage volume loss is considered a key feature of knee osteoarthritis (OA) and increased loss over two years is associated with future knee replacement…
Abstract Number: 2155 • 2013 ACR/ARHP Annual Meeting
Beneficial Effect Of Long-Term Use Of a Low-Cost Minimalist Footwear On Joint Load, Clinical, and Functional Aspects Of Elderly Women With Knee Osteoarthritis
Francis Trombini-Souza¹, Alessandra Matias¹, Mariane Yokota¹, Marco Butugan¹, Ivye Pereira¹, Claudia Goldenstein-Schainberg², Ricardo Fuller³ and Isabel C.N. Sacco¹, ¹Physical Therapy, Speech and Occupational Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil, ²Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ³Division of Rheumatology - Hospital das Clinicas - Medical School, University of Sao Paulo, São Paulo, Brazil
Background/Purpose: Positive outcomes of minimalist shoes on reduction of overload in patients with knee osteoarthritis (OA) have been highlighted. We have recently shown beneficial effects…
Abstract Number: 1132 • 2013 ACR/ARHP Annual Meeting
Sensitivity To Change Of Radiographic Fixed-Location and Magnetic Resonance Imaging-Based Cartilage Thickness Measures In The Lateral Compartment Of Knees With Radiographic Osteoarthritis – Data From The Osteoarthritis Initiative
Wolfgang Wirth¹, Jeffrey W. Duryea², Michael C. Nevitt³, Robert J. Buck⁴, David Hunter⁵ and Felix Eckstein¹, ¹Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ²Radiology, Brigham and Women's Hospital, Boston, MA, ³Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁴StatAnswers Consulting, Minneapolis, MN, ⁵Royal North Shore Hospital, St. Leonards, Australia
Background/Purpose: Radiographic joint space width (JSW) is frequently employed to indirectly assess structural progression in the medial femorotibial compartment, but it is unclear whether assessment…
Abstract Number: 99 • 2013 ACR/ARHP Annual Meeting
Twenty-First Century Prevalence Of Frequent Knee Pain, Radiographic, Symptomatic and Clinical Knee Osteoarthritis According to American College Of Rheumatology Criteria In Southern Sweden
Aleksandra Turkiewicz¹, Maria Gerhardsson de Verdier², Gunnar Engström³, Stefan Lohmander¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Astra Zeneca R&D Molndal, Molndal, Sweden, Molndal, Sweden, ³Dept of Cardiovascular epidemiology, Clinical Sciences, Lund University, Lund, Sweden
Background/Purpose: To provide current estimates of the prevalence of knee pain, radiographic, symptomatic, and clinical knee osteoarthritis (OA) in middle-aged and elderly in Sweden. Methods:…
Abstract Number: 2156 • 2013 ACR/ARHP Annual Meeting
Weight Change Has A Disease Modifying Effect On Knee Structure and Symptoms In Obese Individuals Without Diagnosed Knee Osteoarthritis
Andrew Teichtahl¹, Anita Wluka², Stephanie Tanamas³, Yuanyuan Wang³, Boyd Strauss³, Joseph Proietto⁴, John Dixon⁵, Graeme Jones⁶, Andrew Forbes³ and Flavia Cicuttini⁷, ¹Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, ²Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, ³Monash University, Melbourne, Australia, ⁴University of Melbourne, Melbourne, Australia, ⁵Baker Institute, Melbourne, Australia, ⁶Menzies Research Institute, Tasmania, Australia, ⁷Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia
Background/Purpose: Although the strongest modifiable risk factor for the development of knee osteoarthritis (OA) is obesity, there are a paucity of data examining the effects…
Abstract Number: 1130 • 2013 ACR/ARHP Annual Meeting
Change In Knee Osteophyte Volume By Semi-Automated Method In Knee Osteoarthritis Over Four Years Using 3T DESS 3D MRI
Michael Hakky¹, Charles Ratzlaff², Ali Guermazi³, Mohamed Jarraya⁴ and Jeffrey W. Duryea⁵, ¹Radiology, Lahey Clinic, Burlington, MA, ²Harvard Medical School / Brigham and Women's Hospital, Boston, MA, ³Boston University, Boston, MA, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, ⁵Radiology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: The development and growth of osteophytes are considered a radiographic surrogate for osteoarthritis (OA) at the knee. Methods to determine osteophyte burden are largely…
Abstract Number: L19 • 2013 ACR/ARHP Annual Meeting
Kellgren-Lawrence Grade (KL) 0 Vs. KL 1 Knees Differ in Their MRI Predictors of Subsequent Radiographic Osteoarthritis
C.Kent Kwoh¹, Ali Guermazi², Tomoko Fujii³, Robert M. Boudreau³, Michael Hannon⁴, Jason Grago⁴, David Hunter⁵, Felix Eckstein⁶ and Frank Roemer⁷, ¹Department of Medicine, The University of Arizona Arthritis Center, Tucson, AZ, ²Radiology, Boston University School of Medicine, Boston, MA, ³Epidemiology, University of Pittsburgh, Pittsburgh, PA, ⁴Medicine, University of Pittsburgh, Pittsburgh, PA, ⁵University of Sydney, Sydney, Australia, ⁶Paracelsus Medical University, Salzburg, Austria, ⁷Klinikum Augsburg, Augsburg, Germany
Background/Purpose: Kellgren-Lawrence grade (KL) 1, defined by a questionable osteophyte and/or doubtful joint space narrowing, is thought to be an intermediate stage from non-OA (i.e.,…
Abstract Number: 73 • 2013 ACR/ARHP Annual Meeting
Fibrillin-1 Expression and Function Is Needed For Normal Joint Function and Mutations Leads To Osteoarthritis
Wasabha Ramanayake¹, Helen Jones¹, Isabel Orriss², Tim Arnett², Andrew Pitsillides³, Christopher P. Denton⁴, David J. Abraham⁴ and Blandine Poulet⁵, ¹Centre for Rheumatology and Connective tissue diseases, UCL Medical School, London, United Kingdom, ²Department of Cell and developmental biology, University College London, London, United Kingdom, ³Department of Comparative Biomedical Sciences, Royal Veterniary College, London, United Kingdom, ⁴Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, London, United Kingdom, ⁵Centre for Rheumarology and connective tissue diseases, UCL Medical School, London, United Kingdom
Background/Purpose: Osteoarthritis (OA) is a common degenerative disease leading to pain and disability in >6million british people. The TGFb signalling pathway has been shown to…
Abstract Number: 2130 • 2013 ACR/ARHP Annual Meeting
Factors Associated With Two-Year Pain Experience Outcome In Knee Osteoarthritis
Jamie E. Rayahin¹, Joan S. Chmiel², Orit Almagor², Laura Belisle², Alison H. Chang³, Kirsten Moisio², Karen W. Hayes², Yunhui Zhang² and Leena Sharma², ¹University of Illinois, Chicago, Chicago, IL, ²Northwestern University, Chicago, IL, ³Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL
Background/Purpose: Few strategies to improve pain outcome in knee OA exist, in part because methods to evaluate this outcome are not established. ICOAP development…
Abstract Number: 993 • 2013 ACR/ARHP Annual Meeting
An Analysis Of Healthcare Resource Utilization Among Patients Undergoing Total Knee Arthroplasty In The United Kingdom
Mireia Raluy¹, Michael Schoenfeld², Dimitra Lambrelli¹, Meng Wang³, Ning Wu⁴, Shih-Yin Chen⁴ and Russel Burge², ¹Health Economics, United BioSource Corporation, London, United Kingdom, ²Global Health Outcomes, Eli Lilly and Company, Indianapolis, IN, ³Economic Analysis and Solutions, United BioSource Corporation, London, United Kingdom, ⁴Economic Analysis and Solutions, United BioSource Corporation, Lexington, MA
Background/Purpose: Elective total knee arthroplasty (eTkA) is among the most commonly performed surgical procedures. The typical reasons for eTkA are pain and decreased quality of…

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