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Abstract Number: 2119

Higher Mortality In Males Compared To Females Undergoing Total Knee Or Total Hip Arthroplasty: A Study Of National Time Trends, 2003-2010

Jasvinder A. Singh1,2 and Rekha Ramachandaran3, 1Rheumatology, Birmingham VA, Birmingham, AL, 2Department of Medicine, University of Alabama, Tuscaloosa, AL, 3University of Alabama at Birmingham, Birmingham, AL

Meeting: 2013 ACR/ARHP Annual Meeting

Keywords: Arthroplasty, epidemiologic methods and morbidity and mortality, Hip, Knee

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Session Information

Session Title: Orthopedics, Low Back Pain and Rehabilitation

Session Type: Abstract Submissions (ACR)

Background/Purpose: To assess the time-trends in gender differences in mortality after primary total knee and total hip arthroplasty (TKA and THA) by rural or urban residence.

Methods: We used the Nationwide Inpatient Sample (NIS) data from 1998 to 2010 to examine time-trends by gender in TKA and THA. Rates were calculated for the U.S. population.

Results: Mortality rates were higher in males compared to females through the study period.  In 2003, mortality rates in rural females, rural males, urban females and urban males after primary TKA were: 115, 279, 140 and 230 per 100,000, respectively.  Respective numbers for primary THA were: 326, 346, 360 and 168. In 2010, similar differences were seen by gender in both rural and urban dwelling females and males: (1) urban: 70, 92, 29 and 131; and (2) rural 145, 154, 94, 211, respectively.  In all cohorts, a significant reduction in mortality was noted.  The rate of reduction of mortality over time was most noticeable in rural-dwelling women among all groups.

Conclusion: The mortality rates following primary TKA and THA has decreased significantly over the last 7 years from 2003 to 2010.  Mortality is higher in males compared to females, a difference that has not changed over time.  More insights are need into understanding what factors contribute to lower mortality in females. 

 Table 1. Mortality per 100,000 by gender in rural/urban residents

Urban Residence

 

THA

TKA

 

 

Female

Male

Female

Male

 

2003

115.3

278.7

326.2

345.8

 

2004

104.7

199.0

251.6

238.3

 

2005

81.8

144.5

212.4

209.2

 

2006

76.1

153.6

171.6

213.5

 

2007

66.2

114.8

157.1

237.6

 

2008

82.3

123.2

173.1

173.0

 

2009

60.0

85.8

152.3

171.0

 

2010

69.5

92.1

144.8

154.2

 

 

 

 

 

 

 

Rural residence

 

THA

TKA

 

 

Female

Male

Female

Male

 

2003

139.7

230.1

360.1

167.6

 

2004

119.8

144.3

462.2

307.7

 

2005

151.5

138.7

189.9

357.5

 

2006

79.3

161.1

199.7

239.1

 

2007

63.9

107.1

268.8

244.4

 

2008

51.4

115.1

273.4

259.7

 

2009

51.7

136.6

183.3

169.2

 

2010

28.8

131.4

94.4

211.3

 


Disclosure:

J. A. Singh,

Takeda, Savient,

2,

Savient, Takeda, Ardea, Regeneron, Allergan,

5,

URL pharmaceuicals Novartis,

5;

R. Ramachandaran,
None.

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