Abstracts tagged "Knee"

Abstract Number: 2755 • 2013 ACR/ARHP Annual Meeting
The Clinical Significance and Natural History Of Knee Bone Marrow Lesions Over 8 Years
Yi Chao Foong¹, Hussain Ijaz Khan¹, Dawn Aitken¹, Changhai Ding², Flavia Cicuttini³ and Graeme Jones², ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia
Background/Purpose: There is increasing evidence to suggest that bone marrow lesions (BMLs) play a key role in the pathogenesis of OA. Whilst many studies have…
Abstract Number: 2111 • 2013 ACR/ARHP Annual Meeting
The Impact Of Centralized Pain On Long-Term Analgesic Response To Lower Extremity Joint Arthroplasty: A Prospective, Observational Cohort Study
Chad M. Brummett¹, Andrew Urquhart², Brian Hallstrom², Alex Tsodikov³, David A. Williams⁴ and Daniel J. Clauw⁵, ¹Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, ²Orthopedics, University of Michigan Health System, Ann Arbor, MI, ³Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, ⁴Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI, ⁵Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI
Background/Purpose : In cross-sectional studies, depression and pain in other locations have been reported as predicting poorer outcomes following total knee and hip arthroplasty. These…
Abstract Number: 244 • 2013 ACR/ARHP Annual Meeting
Association Between Serum Adipokine Levels and Extent Of Symptomatic Joint Involvement In Hip and Knee Osteoarthritis
Anthony V. Perruccio¹, Vinod Chandran², Nizar N. Mahomed³ and Rajiv Gandhi⁴, ¹Toronto Western Hospital, Toronto Western Research Institute, and University of Toronto, Toronto, ON, Canada, ²Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Orthopaedic Surgery, University Health Network and University of Toronto, Toronto, ON, Canada, ⁴University Health Network, Arthritis Program, Toronto, ON, Canada
Background/Purpose: Osteoarthritis (OA) has not traditionally been considered a systemic joint disease. However, a growing body of evidence suggests that OA cannot solely be accounted…
Abstract Number: 2668 • 2013 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Dose Ranging Study Comparing FX006, An Intra-Articular (IA) Sustained-Release Formulation Of Triamcinolone Acetonide (TCA), To An Approved Injectable Suspension Of TCA In Patients With Osteoarthritis (OA) Of The Knee
Neil Bodick¹, Joelle Lufkin¹, Christina Willwerth¹, Pierre Lachance², Gregory Jasey³, Anil Gupta⁴, Anthony Chris⁵, Marc Russo⁶, Michael O'Mahony⁷, Sam Henein⁸, Louise Murdoch⁹, Ferdinandus de Looze¹⁰, David Hunter¹¹ and Michael Clayman¹, ¹Flexion Therapeutics, Burlington, MA, ²Clinique St-Louis (Recherche) Inc, Quebec, QC, Canada, ³North Walkerville Orthopaedic Associates, Windsor, ON, Canada, ⁴Anil K. Gupta Medicine Professional Corporation, Toronto, ON, Canada, ⁵Aim Health Group, Waterloo, ON, Canada, ⁶Hunter Clinical Research, Broadmeadow, Australia, ⁷London Road Diagnostic Clinic and Medical Centre, Sarnia, ON, Canada, ⁸SKDS Research Inc., Newmarket, ON, Canada, ⁹Emeritus Research, Malvern East, Australia, ¹⁰AusTrials Pty Limited, Sherwood, Australia, ¹¹Royal North Shore Hospital, St. Leonards, Australia
Background/Purpose: FX006 is a novel sustained-release formulation of TCA in poly(lactic-co-glycolic) acid microspheres intended to maintain therapeutic concentrations in the joint up to 3 months…
Abstract Number: 2112 • 2013 ACR/ARHP Annual Meeting
Hip and Knee Arthroplasty In Patients With Rheumatoid Arthritis: Results From The Australian Orthopaedic Association National Joint Replacement Registry: 2003 To 2011
Andrew Lim¹, Stephen Graves², Yen Liu², Lionel Schachna¹ and Russell R. Buchanan¹, ¹Rheumatology, Austin Health, Melbourne, Australia, ²Australian Orthopaedic Association National Joint Replacement Registry, Adelaide, Australia
Background/Purpose: Total Joint Replacement in rheumatoid arthritis (RA) patients is a marker of disease severity. Whilst the rate of total hip (THA) and total knee…
Abstract Number: 247 • 2013 ACR/ARHP Annual Meeting
Associations Between Levels Of Urinary C-Telopeptide Fragments Of Type II Collagen and Knee Structure In Asymptomatic Middle-Aged Women
Binghui Wang¹, Hans Kurniawan Pramono², Flavia Cicuttini³, Anita Wluka³, Fahad Hanna², Susan Davis², Robin Bell², Andrew Teichtahl¹ and Yuanyuan Wang², ¹Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, ²Monash University, Melbourne, Australia, ³Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: There is evidence for an association between levels of urinary C-telopeptide fragments of type II collagen (uCTX-II) and the risk of knee osteoarthritis. The…
Abstract Number: 2669 • 2013 ACR/ARHP Annual Meeting
Treatment Of Knee Osteoarthritis Patients With Strontium Ranelate Reduces The Loss Of Cartilage Volume and Bone Marrow Lesions As Assessed By Magnetic Resonance Imaging: Data From The Phase III Strontium Ranelate Efficacy In Knee Osteoarthrtis Trial
Johanne Martel-Pelletier¹, Camille Roubille¹, Jean-Pierre Raynauld¹, François Abram², Marc Dorais³, Philippe Delorme¹ and Jean-Pierre Pelletier¹, ¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ²Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ³StatSciences Inc., Notre-Dame de l’Île Perrot, QC, Canada
Background/Purpose: This study aimed to evaluate in a subpopulation of osteoarthritis (OA) patients from the SEKOIA Phase III trial the disease-modifying (DMOAD) effect of strontium…
Abstract Number: 2119 • 2013 ACR/ARHP Annual Meeting
Higher Mortality In Males Compared To Females Undergoing Total Knee Or Total Hip Arthroplasty: A Study Of National Time Trends, 2003-2010
Jasvinder A. Singh^1,2 and Rekha Ramachandaran³, ¹Rheumatology, Birmingham VA, Birmingham, AL, ²Department of Medicine, University of Alabama, Tuscaloosa, AL, ³University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: To assess the time-trends in gender differences in mortality after primary total knee and total hip arthroplasty (TKA and THA) by rural or urban…
Abstract Number: 250 • 2013 ACR/ARHP Annual Meeting
Synovial Inflammation In Meniscal Tear Patients: CCL19 mRNA Expression Is Independently Associated With Knee Related Disability
Anjali Nair¹, Charles Bush-Joseph², Nikhil Verma², Matthew Tetreault², Kanta Saha³, Arkady Margulis⁴, Louis F. Fogg⁵ and Carla R. Scanzello³, ¹Section of Rheumatology, Rush University Medical Center, Chicago, IL, ²Orthopedics, Rush University Medical Center, Chicago, IL, ³Rheumatology, Rush University Medical Center, Chicago, IL, ⁴Rush University Medical Center, Chicago, IL, ⁵Department of Nursing, Rush University Medical Center, Chicago, IL
Background/Purpose: In patients with knee osteoarthritis (OA), synovitis is associated with severity of knee symptoms. Previously, we demonstrated that in patients undergoing partial meniscectomy without…
Abstract Number: 2670 • 2013 ACR/ARHP Annual Meeting
Does Change In Femorotibial Cartilage Thickness Differ Between Acutely Anterior-Cruciate Ligament Injured Knees Treated With and Without Reconstructive Surgery
Wolfgang Wirth¹, Felix Eckstein¹, Martin Hudelmaier², Stefan Lohmander³ and Richard Frobell⁴, ¹Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ²Paracelsus Medical University, Salzburg, Austria, ³Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ⁴Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: An ACL tear is a serious knee injury, involving chronic alterations in joint biomechanics. The risk of developing knee OA after an ACL tear…
Abstract Number: 1932 • 2013 ACR/ARHP Annual Meeting
Shared Decision Making In Early Knee Osteoarthritis: Perspectives Of Older Adults With Overweight and Obesity and Health Care Providers
Alicia Zbehlik^1,2, Mary Meinke³ and Stephen Bartels⁴, ¹Rheumatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, ²The Geisel School of Medicine at Dartmouth, The Dartmouth Centers for Health and Aging, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, ³The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, ⁴The Geisel School of Medicine at Dartmouth, The Dartmouth Centers for Health and Aging, Lebanon, NH
Background/Purpose: Knee osteoarthritis (KOA) is the most common form of mobility disability in the United States yet those at highest risk—older adults with overweight and…
Abstract Number: 252 • 2013 ACR/ARHP Annual Meeting
The Association Of Knee Buckling With Vibratory Perception and Muscle Strength: The Multicenter Osteoarthritis Study
Najia Shakoor¹, David T. Felson², Jingbo Niu³, Neil A. Segal⁴, Uyen Sa D.T. Nguyen⁵, Jasvinder A. Singh⁶ and Michael C. Nevitt⁷, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁵Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁶Department of Medicine, University of Alabama, Tuscaloosa, AL, ⁷Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA
Background/Purpose: Knee buckling (“giving way”) is a common symptom in knee osteoarthritis (OA). Yet, little is known regarding risk factors for buckling. Knee buckling has…
Abstract Number: 2671 • 2013 ACR/ARHP Annual Meeting
The Relationship Between Toe-Out Angle During Walking and Risk Of Medial Knee Osteoarthritis Incidence: The Multicenter Osteoarthritis Study
K. Douglas Gross¹, Yuqing Zhang¹, Emily K. Quinn², Michael C. Nevitt³, Neil A. Segal⁴, Cora E. Lewis⁵ and David T. Felson¹, ¹Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Unit, Boston University, Boston, MA, ³Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁴Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁵Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL
Background/Purpose: A previous study suggests a linear relationship between increased toe-out angle during walking and reduced risk of medial knee OA progression. Yet, gait lab…
Abstract Number: 1926 • 2013 ACR/ARHP Annual Meeting
Validation Of The Hospital For Special Surgery Knee Questionnaire: Convergent Validity, Responsiveness and Sensitivity To Change
Jasvinder A. Singh^1,2, Cathy Schleck³, W. Scott Harmsen⁴ and David Lewallen⁵, ¹Rheumatology, Birmingham VA, Birmingham, AL, ²Department of Medicine, University of Alabama, Tuscaloosa, AL, ³Mayo Clinic College of Medicine, Rochester, MN, ⁴Mayo Clinic, Rochester, MN, ⁵Orthopedics, Mayo Clinic college of medicine, Rochester, MN
Background/Purpose: Hospital for Special Surgery (HSS) Knee questionnaire has previously been shown to have construct validity. Our objective was to further assess the validity and responsiveness…
Abstract Number: 254 • 2013 ACR/ARHP Annual Meeting
The Relationship Of Foot Pronation During Walking To Risk Of Incident Medial Tibiofemoral and Lateral Patellofemoral Cartilage Damage: The Multicenter Osteoarthritis Study
K. Douglas Gross¹, Howard J. Hillstrom², Yuqing Zhang¹, Emily K. Quinn³, Michael C. Nevitt⁴, Neil A. Segal⁵, Cora E. Lewis⁶ and David T. Felson¹, ¹Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ²Rehabilitation, Hospital Special Surgery (HSS), New York, NY, ³Clinical Epidemiology Unit, Boston University, Boston, MA, ⁴Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁵Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁶Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL
Background/Purpose: Studies of older adults suggest an association between plantar pressure measures of foot pronation and medial tibiofemoral (med TF) cartilage damage, while studies of…

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