Abstracts tagged "juvenile idiopathic arthritis (JIA)"

Abstract Number: 915 • 2019 ACR/ARP Annual Meeting
Development and Initial Validation of the Systemic JADAS, a New Composite Disease Activity Score for Systemic Juvenile Idiopathic Arthritis
Jessica Tibaldi¹, Yasser El Miedany ², Pryiankar Pal ³, Soamarat Vilaiyuk ⁴, Raju Khubchandani ⁵, Manuela Pardeo ⁶, Tapas Kumar Sabui ⁷, Sujata Sawhney ⁸, Ricardo Russo ⁹, Flavio Sztajnbok ¹⁰, Rolando Cimaz ¹¹, Francesca Minoia ¹², Motasem O. Alsuweiti ¹³, Ekaterina Alexeeva ¹⁴, Mikhail Kostik ¹⁵, Maria Cristina Maggio ¹⁶, Sulayman Al Mayouf ¹⁷, Claudia Saad ¹⁸, Giovanni Conti ¹⁹, Romina Gallizzi ²⁰, Adele Civino ²¹, Masaki Shimizu ²², Enrico Felici ²³, Angela Pistorio ²⁴, Nicolino Ruperto ²⁵, Alessandro Consolaro ²⁶ and Angelo Ravelli ²⁷, ¹IRCCS Istituto Giannina Gaslini, Università degli Studi di Genova, Genoa, Italy, ²Ain Shams University, Cairo, Egypt, ³Institute of Child Health, Kolkata, India, ⁴Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, ⁵Jaslok Hospital and Research Center, Mumbai, India, ⁶Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, Rome, Italy, ⁷R G Kar Medical College, Kolkata, Kolkata, India, ⁸Department of pediatric rheumatology, Sir Ganga Ram Hospital, New Delhi, India, New Delhi, India, ⁹Hospital de Pediatría Garrahan, Buenos Aires, Argentina, ¹⁰Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, ¹¹University Hospital Meyer, Florence, Italy, ¹²Clinica De Marchi Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, ¹³Queen Rania Children's Hospital, Amman, Jordan, ¹⁴National Medical Research Center of Children`s Health, Moscow, Russia, ¹⁵Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russia, ¹⁶Università di Palermo, Dipartimento G. D'Alessandro, Palermo, Italy, ¹⁷King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, ¹⁸Hospital das Clínicas - Botucatu Medicine University, UNESP, Botucatu, Brazil, ¹⁹AOU G Martino, Messina, Italy, ²⁰Azienda Ospedaliera Universitaria Gaetano Martino, Messina, Messina, Italy, ²¹Pediatric Rheumatology “Vito Fazzi” Hospital, Lecce, Lecce, Italy, ²²Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa, Japan, ²³SS Antonio e Biagio e Cesare Arrigo" Hospital, Alessandria, Italy, ²⁴IRCCS Istituto Giannina Gaslini, Genova, Italy, ²⁵Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, ²⁶Università degli Studi di Genova, Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DiNOGMI), Genoa, Italy and IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, Genoa, Italy, Genova, Italy, ²⁷IRCCS Istituto Giannina Gaslini, Università degli Studi di Genova, Genova, Italy
Background/Purpose: The Juvenile Arthritis Disease Activity Score (JADAS) has gained increasing popularity for the measurement of the level of disease activity in patients with juvenile…
Abstract Number: 2702 • 2019 ACR/ARP Annual Meeting
Patients’ and Parents’ Perception of Disease and Its Impact on Life in Juvenile Idiopathic Arthritis: Results from Multinational Virtual Focus Groups by the OMERACT JIA Working Group
Alessandra Alongi¹, Serana Calandra ¹, Susan Thornhill ², Jennifer Stinson ³, Jen Horonjeff ⁴, Daniel Horton ⁵, Alessandro Consolaro ⁶ and Esi Morgan ⁷, ¹Università degli Studi di Genova, Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DiNOGMI), Genoa, Italy and IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, Genoa, Italy, Genoa, ²Thornhill Associates, Hermosa Beach, USA, Hermosa Beach, ³The Hospital for Sick Children, and University of Toronto, Toronto, Canada, Toronto, ⁴Columbia University Medical Center, New York, USA, New York, ⁵Division of Pediatric Rheumatology, Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, Institute for Health, Health Care Policy and Aging Research, Rutgers Biomedical and Health Sciences, New Brunswick, ⁶Università degli Studi di Genova, Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DiNOGMI), Genoa, Italy and IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, Genoa, Italy, Genova, Italy, ⁷Cincinnati Children’s Hospital, University of Cincinnati, Cinncinati, OH
Background/Purpose: The OMERACT Juvenile Idiopathic Arthritis Core Set Working Group formed in 2015 as an international initiative to revise the existing Core Set with relevant…
Abstract Number: 916 • 2019 ACR/ARP Annual Meeting
Development and Initial Validation of the MS Score for Diagnosis of Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis
Francesca Minoia¹, Francesca Bovis ², Sergio Davì ³, AnnaCarin Horne ⁴, Michel Fischbach ⁵, Michael Frosch ⁶, Adam Huber ⁷, Marija Jelusic ⁸, Sujata Sawhney ⁹, Deborah McCurdy ¹⁰, Clovis Artur Silva ¹¹, Donato Rigante ¹², Erbil Unsal ¹³, Nicolino Ruperto ¹⁴, Alberto Martini ¹⁵, Randy Cron ¹⁶ and Angelo Ravelli ¹⁵, ¹Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Lombardia, Italy, ²Università degli Studi di Genova, Genoa, Italy, ³IRCCS Istituto Giannina Gaslini, Genova, Italy, ⁴Karolinska University Hospital, Stockholm, Sweden, ⁵Hopital Universitaire Hautepierre, Strasbourg, France, ⁶School of Medicine Witten/Herdecke University, Datteln, Germany, ⁷IWK Health Centre, Halifax, NS, Canada, ⁸University of Zagreb, Zagreb, Croatia, ⁹Sir Ganga Ram Hospital, New Delhi, India, ¹⁰University of California, MDCC 12-430, 10833 Le Conte Ave, Los Angeles, 90095, CA, USA, Los Angeles, ¹¹Childrens’ Institute, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, ¹²Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ¹³Dokuz Eylul University, School of Medicie, Izmir, Turkey, ¹⁴Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, ¹⁵IRCCS Istituto Giannina Gaslini, Università degli Studi di Genova, Genova, Italy, ¹⁶University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Macrophage activation syndrome (MAS) is the most severe complication of systemic juvenile idiopathic arthritis (sJIA) and its adult equivalent, adult-onset Still’s disease (AOSD). Because…
Abstract Number: 2704 • 2019 ACR/ARP Annual Meeting
Injection Fear in Juvenile Idiopathic Arthritis Patients Using Injectable Medications
Kathleen Collins¹, Anava Wren ² and Tzielan Lee ², ¹Stanford University School of Medicine, Palo Alto, CA, ²Stanford University School of Medicine, Palo Alto
Background/Purpose: Injectable medications are frequently used to treat Juvenile Idiopathic Arthritis (JIA). Fear of pain and needle fear have been identified as barriers to injectable…
Abstract Number: 1125 • 2019 ACR/ARP Annual Meeting
Health Care Resource Utilization and Costs in Patients with Juvenile Idiopathic Arthritis Treated with Abatacept and Other Targeted Disease Modifying Anti-rheumatic Drugs
Joe Zhuo¹, Ying Bao ², Qian Xia ², Aarti Rao ³, Niyati Sharma ³, Xue Han ⁴ and Robert Wong ⁵, ¹Bristol-Myers Squibb, Princeton, NJ, ²Bristol-Myers Squibb, Lawrenceville, NJ, ³Mu Sigma, Bangalore, India, ⁴Bristol-Myers Squibb Company, Princeton, NJ, ⁵Bristol-Myers Squibb, Princeton
Background/Purpose: Juvenile idiopathic arthritis (JIA) is a common, chronic rheumatic disease of childhood that carries substantial economic impact on patients (pts) and families1. The objective…
Abstract Number: 2705 • 2019 ACR/ARP Annual Meeting
Profiling Behavioral and Psychological Symptoms in Children with Spondyloarthritis and Polyarthritis
Anne McHugh¹, Avis Chan ², Carolyn Herrera ², Margo Thienemann ² and Jennifer Frankovich ², ¹Stanford University School of Medicine, Palo Alto, CA, ²Stanford University School of Medicine, Palo Alto
Background/Purpose: Mental health disorders are thought to be common in patients with rheumatic disease, but studies examining behavioral issues in patients with juvenile idiopathic arthritis…
Abstract Number: 170 • 2019 ACR/ARP Annual Meeting
Evaluating an Illustrated Storybook for Children with Juvenile Idiopathic Arthritis
Jimin Lee¹, Dennis Newhook ², Kaylee Eady ² and Roman Jurencak ¹, ¹Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, ²CHEO Research Institute, Ottawa, ON, Canada
Background/Purpose: While juvenile idiopathic arthritis (JIA) is a common pediatric rheumatic disease, there is a lack of available child-friendly patient education materials. An illustrated storybook…
Abstract Number: 1174 • 2019 ACR/ARP Annual Meeting
Prevalence of Subclinical Sacroiliitis in Young Patients with Inflammatory Bowel Disease Revealed by Entero-MRI
Teresa Giani¹, Marco Di Maurizio ², Paolo Lionetti ², Azzurra Bernardini ², Giovanna Ferrara ¹, Viola Filistrucchi ² and Rolando Cimaz ³, ¹Anna Meyer Children University Hospital, Florence, Italy, ²A. Meyer Children University Hospital, Florence, Italy, ³Meyer Children's Hospital in Florence, Florence, Italy
Background/Purpose: Sacroiliitis is one of the extraintestinal manifestations associated with inflammatory bowel disease (IBD), and may be underdiagnosed especially in the pediatric age. MR-enterography (Entero-MRI)…
Abstract Number: 2706 • 2019 ACR/ARP Annual Meeting
Association of Body Mass Index with Juvenile Idiopathic Arthritis Disease Activity: A Portuguese and Brazilian Collaborative Analysis with Data from Reuma.pt Registry
Agna Neto¹, Ana Filipa Mourão ², Filipa Oliveira-Ramos ³, Raquel Marques ³, Paula Estanqueiro ⁴, Manuel Salgado ⁴, Margarida Guedes ⁵, Daniela Piotto ⁶, Clovis Artur Silva ⁷, José Melo Gomes ⁸, Marta Cabral ⁹, Marta Conde ¹⁰, Ricardo Figueira ¹¹, Maria José Santos ¹², João Eurico Fonseca ¹³, Maria Teresa Terreri ⁶ and Helena Canhão ¹⁴, ¹Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon; Hospital Central do Funchal, Madeira., Lisbon, Portugal, ²Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon, Lisbon, Portugal, ³Rheumatology and Metabolic Bone Diseases, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Lisbon, Portugal, ⁴Pediatrics, Hospital Pediátrico Carmona da Mota, Coimbra, Coimbra, Portugal, ⁵Unidade de Imunologia Clínica, Centro Hospitalar Universitário do Porto, Porto, Portugal, ⁶Pediatric Rheumatology Unit, Universidade Federal de São Paulo, São Paulo, Brazil, ⁷Universidade de São Paulo, São Paulo, Brazil, ⁸Instituto Português de Reumatologia; Clínica Dr. Melo Gomes, Lisbon., Lisbon, Portugal, ⁹Pediatrics, Hospital Prof. Doutor Fernando Fonseca, Lisbon, Lisbon, Portugal, ¹⁰Pediatric Rheumatology Unit, Hospital Dona Estefânia, Centro Hospitalar de Lisboa Central, Lisbon, Lisbon, Portugal, ¹¹Rheumatology Department, Hospital Central do Funchal, Funchal, Madeira, Portugal, ¹²Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ¹³Rheumatology and Bone Diseases Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa; Centro Académico de Medicina de Lisboa; Lisbon, Portugal., Lisbon, Portugal, ¹⁴CEDOC, EpiDoC Unit, NOVA Medical School, Lisbon, Lisbon, Portugal
Background/Purpose: In adults with Rheumatoid Arthritis, obesity has been associated with higher disease activity. However, in Juvenile Idiopathic Arthritis (JIA), the influence of body mass…
Abstract Number: 187 • 2019 ACR/ARP Annual Meeting
Epidemiology of JIA-Associated Uveitis: Environmental Factors and Disease Characteristics of a JIA-Associated Uveitis Cohort
Theresa Hennard ¹, Najima Mwase ², Amy Cassedy ³, Joseph McDonald ⁴, Virginia Utz ⁵ and Sheila Angeles-Han⁶, ¹Division of Rheumatology, Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, ²Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁴Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁵Division of Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cinicinnati
Background/Purpose: JIA-associated uveitis (JIA-U) is the most prevalent extra-articular manifestation of JIA and the most common type of uveitis in children. To date, environmental factors…
Abstract Number: 1201 • 2019 ACR/ARP Annual Meeting
Are We Meeting Benchmarks for Wait Times to Pediatric Rheumatology Care for Juvenile Idiopathic Arthritis (JIA)?
Claire Barber¹, Natalie Shiff ², Cheryl Barnabe ³, Susanne Benseler ³, Ricky Chin ³, Nicole Johnson ³, Nadia Luca ³, Paivi Miettunen ⁴, Marinka Twilt ³, Dwaraka Veeramreddy ³ and Heinrike Schmeling ⁵, ¹University of Calgary, Calgary, Canada, ²University of Florida, Gainesville, FL, ³University of Calgary, Calgary, AB, Canada, ⁴Alberta Children's Hospital, Calgary, ON, Canada, ⁵Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
Background/Purpose: Wait time to pediatric rheumatology care for patients with Juvenile Idiopathic Arthritis (JIA) is a nationally endorsed quality measure in Canada. Target wait times…
Abstract Number: 2710 • 2019 ACR/ARP Annual Meeting
Sarilumab, a Human Monoclonal Antibody to the Interleukin-6 Receptor, in Polyarticular-course Juvenile Idiopathic Arthritis: A 12-week, Multinational, Open-label, Dose-finding Study
Fabrizio De Benedetti¹, Inmaculada Calvo Penadés ², Nadina Rubio-Pérez ³, Alexey Maschan ⁴, Pierre Quartier ⁵, Zbigniew Żuber ⁶, Marina Stanislav ⁷, Raul Barria ⁸, Daniel Clemente ⁹, Gabriel Vega-Cornejo ¹⁰, Nancy Liu ¹¹, Christine Xu ¹¹, Angeliki Giannelou ¹², Bolanle Akinlade ¹² and Lydie Baret-Cormel ¹³, ¹Bambino Gesù Children’s Hospital, Rome, Italy, ²Hospital Univ. La Fe, Valencia, Spain, ³University Hospital Dr. José Eleuterio González, Monterrey, Mexico, ⁴Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russia, ⁵Necker Hospital, Paris, France, ⁶Andrzej Frycz Modrzewski Krakow University, Kraków, Poland, ⁷V.A. Nasonova Research Rheumatology Institute, Moscow, Russia, ⁸Bioreuma, Concepción, Chile, ⁹Hospital Infantil Universitario Niño Jesús, Madrid, Spain, ¹⁰CREA de Guadalajara, Jalisco, Mexico, ¹¹Sanofi, Bridgewater, NJ, ¹²Regeneron, New York, NY, ¹³Sanofi, Chilly-Mazarin, France
Background/Purpose: Sarilumab blocks interleukin-6 (IL-6) from binding to membrane and soluble IL-6 receptor-α. Sarilumab is approved for adults with rheumatoid arthritis (RA) and is being…
Abstract Number: 188 • 2019 ACR/ARP Annual Meeting
The Importance of Diagnosis: Clinical Distinctions Between Adult JIA and RA, and a Characterization of Patients with JIA Reclassified as RA in Adulthood
Kristin Wipfler¹, Sofia Pedro ¹, Yomei Shaw ¹, Rebecca Schumacher ¹, Teresa Simon ², Alyssa Dominique ³, Adam Reinhardt ⁴ and Kaleb Michaud ⁵, ¹FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, ²Bristol-Myers Squibb*, Princeton, NJ, ³Bristol-Myers Squibb, Princeton, NJ, ⁴Children’s Hospital & Medical Center & University of Nebraska Medical Center, Omaha, NE, ⁵FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS
Background/Purpose: Upon transitioning from pediatric to adult care, many patients with JIA are labeled as having RA, despite the two diagnoses being distinct in care…
Abstract Number: 1814 • 2019 ACR/ARP Annual Meeting
Long-term Outcome of Juvenile Idiopathic Arthritis: From the Methotrexate to the Biologic Era
Gabriella Giancane¹, Valentina Muratore ², Valentina Marzetti ³, Neus Quilis ³, Belen Serrano Benavente ³, Francesca Bagnasco ³, Alessandra Alongi ⁴, Adele Civino ⁵, Alessandro Consolaro ⁶ and Angelo Ravelli ⁷, ¹Università degli Studi di Genova, Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DiNOGMI), Genoa, Italy and IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, Genoa, Italy, Genoa, Italy, ²IRCCS Policlinico San Matteo, Pavia, Lombardia, Italy, ³IRCCS Gaslini, Genoa, ⁴Università degli Studi di Genova, Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DiNOGMI), Genoa, Italy and IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, Genoa, Italy, Genoa, ⁵Pediatric Rheumatology “Vito Fazzi” Hospital, Lecce, Lecce, Italy, ⁶Università degli Studi di Genova, Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DiNOGMI), Genoa, Italy and IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, Genoa, Italy, Genova, Italy, ⁷IRCCS Istituto Giannina Gaslini, Università degli Studi di Genova, Genova, Italy
Background/Purpose: After nearly two decades from the start of the Biologic era, systematic analyses of patients with juvenile idiopathic arthritis (JIA) have shown a high…
Abstract Number: 2711 • 2019 ACR/ARP Annual Meeting
Utilization of Biologic Treatments in Oligoarticular and Polyarticular Juvenile Idiopathic Arthritis
Daniah Basodan¹, Kathleen M Andersen ², Xintong Li ³, Jeffrey Curtis ⁴ and G. Caleb Alexander ⁵, ¹University of Alberta, Edmonton, AB, Canada, ²Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health,, Baltimore, MD, ³Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Johns Hopkins Bloomberg School of Public Health. Center for Drug Safety and Effectiveness, Baltimore, MD
Background/Purpose: In recent years, juvenile idiopathic arthritis (JIA) treatment options have expanded to include biologics such as tumor necrosis factor inhibitors (TNFi) and non-TNF inhibitors…

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