ACR Meeting Abstracts

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Abstracts tagged "inflammatory bowel disease (IBD)"

  • Abstract Number: 136 • 2020 Pediatric Rheumatology Symposium

    Prevalence of Paradoxical Psoriasis After Exposure to Tumor Necrosis Factor Inhibitors (TNFi) in Children from a Single Tertiary Center

    Sarah Kodama1, Deepti Gupta 2, Erin Sullivan 3 and Yongdong Zhao 4, 1School of Medicine, Virginia Commonwealth University, Richmond, 2Pediatric Dermatology, School of Medicine, University of Washington, Seattle, 3Seattle Children's Research Institute, Seattle, 4University of Washington, Seattle

    Background/Purpose: Paradoxical psoriasis after exposure to tumor necrosis factor inhibitors (TNFi) has been increasingly reported in the adult population. Systematic studies in pediatric population are…
  • Abstract Number: 102 • 2020 Pediatric Rheumatology Symposium

    Implications of Positive Tests for ANCA in a Pediatric Population

    Karen James1, Peter Merkel 2 and Aimee Hersh 3, 1University of Utah, 84113, Utah, 2University of Pennsylvania, Philadelphia, 3University of Utah Primary Children's Hospital, Salt Lake City

    Background/Purpose: Testing for ANCA, particularly performed by ELISA (anti-MPO/PR3) is highly sensitive and specific for ANCA-associated vasculitis (AAV). However ANCA testing may be used in…
  • Abstract Number: 558 • 2019 ACR/ARP Annual Meeting

    Frequency and Characteristics of Inflammatory Bowel Disease in Spondyloarthritis with Biological Therapy: Study of 270 Patients from the Same Center

    Itziar Calvo-Zorrilla1, María Luz García-Vivar 1, Oihane Ibarguengoitia-Barrena 1, David Montero-Seisdedos 1, Lucía Vega-Alvarez 1, Juan María Blanco-Madrigal 1, Olaia Begoña Fernandez-Berrizbeitia 1, María Esther Ruiz-Lucea 1, Ignacio Torre-Salaberri 1, Ana Rosa Intxaurbe-Pellejero 1, Clara Eugenia Pérez-Velasquez 1, Eduardo Cuende-Quintana 1, Natalia Andrea Rivera-García 1, María Jesus Allande-López-Linares 1, Helena Ugarte-Zuazo 1, Iñigo Gorostiza-Hormaeche 2 and Eva Galíndez-Agirregoikoa 1, 1Rheumatology Unit, Basurto University Hospital, Bilbao, Spain, Bilbao, Spain, 2Investigation Unit, Basurto University Hospital, Bilbao, Spain, Bilbao, Spain

    Background/Purpose: Inflammatory bowel disease (IBD) is an extra-articular manifestation that can appear in spondyloarthritis (SpA), as well as uveitis and psoriasis. Its prevalence is 5-10%,…
  • Abstract Number: 565 • 2019 ACR/ARP Annual Meeting

    Evidence-Based Recommendations for the Management of Enteropathic Arthritis: A Rheumatology – Gastroenterology Collaborative Initiative

    Gulen Hatemi 1, Servet Akar 2, Hale Akpinar 3, Pamir Atagunduz 4, Goksel Bengi 3, Gercek Can 5, Aykut Ferhat Celik 6, Sinem Nihal Esatoglu7, Onay Gercik 8, Hulya Hamzaoglu 9, Murat Inanc 10, Gokhan Kabacam 11, Ismail Hakki Kalkan 12, Levent Kilic 13, Fatos Onen 14, Ahmet Tezel 15, Murat Toruner 16 and Sedat Kiraz 13, 1Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Behcet's Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, 2Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey, 3Dokuz Eylul University, Faculty of Medicine, Department of Internal Medicine, Division of Gastroenterology, Izmir, Turkey, 4Marmara University Faculty of Medicine,Department of Rheumatology, Istanbul, Turkey, Istanbul, Turkey, 5Dokuz Eylul University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Izmir, Izmir, Turkey, 6Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey, 7Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 8Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, Izmir, Turkey, 9Acibadem University, Acibadem Fulya Hospital, Department of Gastroenterology, Istanbul, Turkey, 10Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 11Ankara Guven Hospital, Department of Gastroenterology, Ankara, Turkey, 12Türkiye Yüksek Ihtisas Training and Research Hospital, Department of Gastroenterology, Ankara, Turkey, 13Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 14Dokuz Eylul University School of Medicine, Division of Rheumatology, İzmir, Turkey, 15Trakya University, Faculty of Medicine, Department of Internal Medicine, Division of Gastroenterology, Edirne, Turkey, 16Ankara University School of Medicine, Department of Gastroenterology,, Ankara, Turkey

    Background/Purpose: Management of enteropathic arthritis may be challenging due to differences in treatment response of inflammatory bowel diseases and arthritis to different therapeutic modalities, which…
  • Abstract Number: 566 • 2019 ACR/ARP Annual Meeting

    Temporal Relationship Between Enteropathic Spondylitis Symptoms/diagnosis and Inflammatory Bowel Diseases Diagnosis: HUR-BIO Real Life Results

    Bayram Farisoğulları1, Gozde Kubra Yardımcı 1, Alper Sarı 1, Berkan Armagan 2, Emre Bilgin 1, Ertugrul Cagri Bolek 1, Levent Kilic 3, Omer Karadag 4, Ali Akdoğan 1, Şule Apras Bilgen 3, Ali İhsan Ertenli 1, Sedat Kiraz 3 and Umut Kalyoncu 5, 1Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, 2Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Ankara, Turkey, 3Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 4Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey, 5Hacettepe University Department of Rheumatology, Ankara, Turkey

    Background/Purpose: The correlation between the time frame of the symptoms/diagnosis of spondylitis and the diagnosis of inflammatory bowel disease (IBD) on patients of enteropathic spondylitis (eSpA) is not precisely…
  • Abstract Number: 579 • 2019 ACR/ARP Annual Meeting

    Is There an Impact of Uveitis, Psoriasis and Inflammatory Bowel Disease on Musculoskeletal Disease Activity and Function in Axial Spondyloarthritis?

    Imke Redeker1, Johanna Callhoff 2, Falk Hoffmann 3, Hildrun Haibel 4, Joachim Sieper 4, Angela Zink 5 and Denis Poddubnyy 6, 1Charité – Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, 2German Rheumatism Research Centre, Berlin, Germany, 3Carl von Ossietzky University, Oldenburg, Germany, 4Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, 5German Rheumatism Research Centre and Charité University medicine, Berlin, Germany, 6Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany

    Background/Purpose: Uveitis, psoriasis and inflammatory bowel disease (IBD) are common in axial spondyloarthritis (axSpA) but data on their impact on activity of musculoskeletal manifestations and…
  • Abstract Number: 613 • 2019 ACR/ARP Annual Meeting

    Can Fecal Calprotectin Predict Future Development of Inflammatory Bowel Disease in Axial Spondyloarthritis Patients? – TReasure Real-Life Preliminary Data

    Gozde Kubra Yardımcı 1, Ozan Cemal içaçan 2, Gokhan Kabadayi 3, Bayram Farisoğulları 1, Cemal Bes 4, Servet Akar 5 and Umut Kalyoncu6, 1Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, 2University of Health Sciences, Bakırköy Sadi Konuk Research and Training Hospital, Rheumatology, İstanbul, 3Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, 4University of Medical Sciences, İstanbul, Turkey, 5Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey, 6Hacettepe University Department of Rheumatology, Ankara, Turkey

    Background/Purpose: Inflammatory bowel disease (IBD) is frequently seen in patients with axial spondyloarthritis (axSpA). This study aimed to investigate whether fecal calprotectin levels could predict…
  • Abstract Number: 1093 • 2019 ACR/ARP Annual Meeting

    The US Prevalence of Inflammatory Bowel Disease and Associated Axial Pain: Data from the National Health & Nutrition Examination Survey (NHANES)

    Oleg Stens1, Charles Dillon 2, Frederick W. Miller 3 and Michael Weisman 4, 1Harbor-UCLA Medical Center, Torrance, CA, 2National Institutes of Health, Bethesda, MD, 3NIEHS, NIH, Bethesda, MD, 4David Geffen School of Medicine at UCLA, Los Angeles, CA

    Background/Purpose: Associations between ulcerative colitis (UC) and Crohn’s disease, known together as inflammatory bowel disease (IBD), with axial pain, inflammatory back pain (IBP) and spondyloarthritis…
  • Abstract Number: 1115 • 2019 ACR/ARP Annual Meeting

    Switching Patterns Among Patients with Chronic Inflammatory Diseases Switching to an Infliximab Biosimilar or Remaining on Originator Infliximab (REMICADE)

    Bruno Emond 1, Kay Sadik 2, Marie-Hélène Lafeuille 1, Willy Wynant 1, Aurélie Côté-Sergent 1, Patrick Lefebvre 1, Kimberly Woodruff 2 and Timothy Fitzgerald3, 1Analysis Group, Inc, Montreal, QC, Canada, 2Janssen Scientific Affairs, LLC, Titusville, NJ, 3Janssen Scientific Affairs, LLC, Horsham, PA

    Background/Purpose: Chronic inflammatory diseases (CIDs) such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), plaque psoriasis (PsO), ankylosing spondylitis (AS), Crohn's disease (CD), and ulcerative colitis…
  • Abstract Number: 1478 • 2019 ACR/ARP Annual Meeting

    Systematic Literature Review and Network Meta-Analysis Comparing Incidence of Uveitis and IBD in Axial Spondyloarthritis Patients Treated with Anti-TNF versus Anti-IL17A in Placebo Controlled Randomized Trials

    Damien Roche1, Martin Badard 1, Laurent Boyer 2, Pierre Lafforgue 1 and Thao Pham 1, 1Aix-Marseille University, CHU Marseille, department of Rheumatology, 13,000 Marseille, France, Marseille, France, 2Aix-Marseille University, EA 3279 Research Unit, 13,000 Marseille, France, Marseille, France

    Background/Purpose: Inflammatory bowel diseases (IBD) and anterior uveitis (AU) are frequent extra-articular features of axial spondyloarthritis (axSpA). Although effect of anti-TNF on IBD and AU…
  • Abstract Number: 1522 • 2019 ACR/ARP Annual Meeting

    Inflammatory Bowel Disease and Anterior Uveitis in Patients Treated with Ixekizumab for Radiographic Axial Spondyloarthritis: Results from Two Phase 3 Studies Through 52 Weeks

    Sergio Schwartzman1, Atul Deodhar 2, Andris Kronbergs 3, Silvia Santisteban 3, Sandra Garces 3, David Sandoval 3, Jeffrey Lisse 3, Fangyi Zhao 3, Denis Poddubnyy 4 and James Rosenbaum 5, 1The Hospital for Special Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, NY, 2Oregon Health & Science University, Portland, OR, 3Eli Lilly and Company, Indianapolis, IN, 4Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, 5Departments of Ophthalmology, Medicine, and Cell Biology, Oregon Health and Science University, Portland, OR

    Background/Purpose: Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory disease involving the axial skeleton; inflammatory bowel disease (IBD) and acute anterior uveitis (AAU) are common…
  • Abstract Number: 699 • 2018 ACR/ARHP Annual Meeting

    New Onset/Recurrence of Inflammatory Arthralgia/Spondyloarthritis in Patients Treated with Vedolizumab for Intestinal Bowel Disease

    Silvia Tamanini1, Micaela Fredi2, Chiara Bazzani1, Maria Grazia Lazzaroni3, Melissa Fernandes4, Cecilia Nalli3, Angela Tincani3 and Franco Franceschini2, 1Rheumatology and Clinical Immunology, Spedali Civili of Brescia, Brescia, Italy, 2Department of Clinical and Experimental Sciences, Spedali Civili and University of Brescia, Brescia, Italy, Rheumatology and Clinical Immunology, Brescia, Italy, 3Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 4Autoimmune Unit/Internal Medicine Department, Hospital Curry Cabral, Centro Hospitalar de Lisboa Central (C.H.L.C), Lisbona, Portugal

    Background/Purpose: Vedolizumab (VDZ) is a monoclonal antibody approved for inflammatory bowel disease, with a gut-specific mechanism of action, binding to α4β7 integrine expressed on gut-homing…
  • Abstract Number: 1828 • 2018 ACR/ARHP Annual Meeting

    Gut-Joint T Cell Trafficking in a Model of Bacteria-Driven Murine IBD-Spa

    Eric Norman1, Adam Lefferts1 and Kristine A Kuhn1,2, 1Rheumatology, University of Colorado Denver, Aurora, CO, 2Mucosal Inflammation Program, University of Colorado Denver, Aurora, CO

    Background/Purpose: Significant bacterial dysbiosis occurs in individuals with IBD and SpA, and individuals with SpA have evidence of circulating intestinal-derived cells, lending credence to the…
  • Abstract Number: 1831 • 2018 ACR/ARHP Annual Meeting

    Intestinal Inflammatory Regulation in Murine and Human Spondyloarthropathy Requires High-Affinity T Cell Receptor-Zeta Chain-Associated Protein (ZAP)70-Mediated Runt-Related Transcription Factor (Runx)3 Activity

    Zaied Ahmed Bhuyan1, M. Arifur Rahman2, Muralidhara Maradana1, Ahmed Mehdi3, Giuliana Guggino4, Paul Leo5, Linda Rehaume1, Matthew Brown5, Francesco Ciccia4 and Ranjeny Thomas1, 1The University of Queensland Diamantina Institute, Brisbane, Australia, 2Translational Research Institute, The University of Queensland Diamantina Institute, Brisbane, Australia, 3Diamantina Institute, The University of Queensland Diamantina Institute, Brisbane, Australia, 4Rheumatology Unit, University of Palermo, Palermo, Italy, 5Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Australia

    Background/Purpose: Loss of function RUNX3 variants are associated with ankylosing spondylitis (AS) risk but the mechanism is unknown. Disturbances in immune regulation, intestinal microbial dysbiosis…
  • Abstract Number: 1866 • 2018 ACR/ARHP Annual Meeting

    Incidence of Inflammatory Bowel Disease Among Patients Treated with Ixekizumab: An Update on Adjudicated Data from an Integrated Database of Patients with Psoriasis and Psoriatic Arthritis

    Mark C. Genovese1, Jean-Frederic Colombel2, Amanda M. Gellett3, Wen Xu3 and Dana Hardin3, 1Department of Medicine, Stanford University, Palo Alto, CA, 2Department of Gastroenterology, The Mount Sinai Hospital, New York, NY, 3Eli Lilly and Company, Indianapolis, IN

    Background/Purpose: Increased incidence of IBD, such as Crohn’s disease (CD) and ulcerative colitis (UC), has been observed in patients (pts) with PsA or plaque psoriasis…
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