Session Type: Poster Session (Sunday)
Session Time: 9:00AM-11:00AM
Background/Purpose: Management of enteropathic arthritis may be challenging due to differences in treatment response of inflammatory bowel diseases and arthritis to different therapeutic modalities, which may even cause worsening of some manifestations while improving others. Enteropathic arthritis was not addressed in the management recommendations for spondyloarthritis. The aim of this project was to develop a set of evidence based recommendations for the management of patients with enteropathic arthritis
Methods: A task force was formed that included ten rheumatologists and 8 gastroenterologists. Research questions were determined using a Delphi approach. A systematic literature search, data extraction, and statistical analyses were performed according to a pre-specified protocol. Studies that assessed the efficacy of an intervention on inflammatory bowel disease-related outcomes and/or spondyloarthritis related outcomes in patients with enteropathic arthritis were included. Risk ratios were calculated for binary outcomes and mean difference for continuous outcomes, whenever possible. Results of the systematic literature review were presented to the experts and recommendations were formulated after thorough discussions and voting.
Results: A total of 4 overarching principles and 10 recommendations were formulated. The recommendations addressed the use of NSAIDs, corticosteroids, sulfasalazine and 5-ASA derivatives, TNF inhibitors, tofacitinib, secukinumab, ustekinumab, and vedolizumab among patients with active inflammatory bowel disease, active arthritis, active disease regarding both inflammatory bowel disease and arthritis, and among patients in remission. Final voting showed a good agreement among the group on all recommendations.
Conclusion: These recommendations are intended to help rheumatologists, gastroenterologists and other clinicians dealing with enteropathic arthritis and to point out to the shortcomings of the available data on the management of this challenging condition.
To cite this abstract in AMA style:Hatemi G, Akar S, Akpinar H, Atagunduz P, Bengi G, Can G, Celik A, Esatoglu S, Gercik O, Hamzaoglu H, Inanc M, Kabacam G, Kalkan I, Kilic L, Onen F, Tezel A, Toruner M, Kiraz S. Evidence-Based Recommendations for the Management of Enteropathic Arthritis: A Rheumatology – Gastroenterology Collaborative Initiative [abstract]. Arthritis Rheumatol. 2019; 71 (suppl 10). https://acrabstracts.org/abstract/evidence-based-recommendations-for-the-management-of-enteropathic-arthritis-a-rheumatology-gastroenterology-collaborative-initiative/. Accessed November 30, 2020.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/evidence-based-recommendations-for-the-management-of-enteropathic-arthritis-a-rheumatology-gastroenterology-collaborative-initiative/