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Abstracts tagged "hypertension"

  • Abstract Number: 338 • ACR/ARP Annual Meeting 2019

    Effect of Serum Urate Lowering with Allopurinol on Blood Pressure in Young Adults

    Angelo Gaffo1, David Calhoun 2, Elizabeth Rahn 1, Suzanne Oparil 2, Peng Li 2, Tanja Dudenbostel 2, David Redden 2, Amy Mudano 2, Jeffrey Foster 1, Daniel Feig 2, Stephanie Biggers 2 and Kenneth Saag 1, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham

    Background/Purpose: The association between serum urate and hypertension continues to be a matter of controversy.  Studies in adolescents provided evidence for the efficacy of urate…
  • Abstract Number: 867 • ACR/ARP Annual Meeting 2019

    Safety and Efficacy of B-cell Depletion with Rituximab for the Treatment of Systemic Sclerosis-associated Pulmonary Arterial Hypertension in a Multi-center NIH Clinical Trial

    Mark Nicolls1, David Badesch 2, Lorinda Chung 3, Robyn Domsic 4, Thomas Medsger 5, Ashley Pinckney 6, Lynette Keyes-Elstein 6, Carla D'Aveta 6, Meagan Spychala 6, R James White 7, Paul Hassoun 8, Fernando Torres 9, Jerry Molitor 10, Dinesh Khanna 11, Holden Maeker 12, Beverly Welch 13, Ellen Goldmuntz 14, Roham Zamanian 1 and -- On Behalf of ASC01 Investigators 15, 1Stanford University, Stanford, 2University of Colorado, Denver, 3Stanford University, Palo Alto, CA, 4University of Pittsburgh, Pittsburgh, PA, 5University of Pittsburgh, Pittsburgh, 6Rho Federal Systems, Durham, 7University of Rochester, Rochester, NY, 8Johns Hopkins School of Medicine, Baltimore, 9UT Southwestern, Dallas, 10University of Minnesota, University of Minnesota, 11Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, 12Stanford, Stanford, 13National Institute of Allergy and Infectious Diseases, NIH, Bethesda, 14NIAID, Washingto, DC, 15---, USA

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a life-threatening complication of systemic sclerosis (SSc). Pre-clinical and clinical data have strongly implicated immune dysregulation and B cell…
  • Abstract Number: 1107 • ACR/ARP Annual Meeting 2019

    Are Rheumatologists Correctly Identifying and Controlling Traditional Cardiovascular Risk Factors?

    Dionicio Galarza-Delgado 1, Jose Azpiri-Lopez 1, Iris Colunga-Pedraza 1, Iván de Jesús Hernández-Galarza 1, Ileana Cecilia Reynosa-Silva1, Karla Paola Cuellar-Calderon 1, Marielva Castro-Gonzalez 1 and Carolina Marlene Martinez-Flores 1, 1Universidad Autonoma de Nuevo Leon, Hospital Universitario "Dr Jose Eleuterio Gonzalez", Monterrey, Nuevo Leon, Mexico

    Background/Purpose: Chronic systemic inflammation generated by rheumatic diseases (RD) is related to the increased cardiovascular risk (CVR) in this population. However, the coexistence of traditional…
  • Abstract Number: 1592 • ACR/ARP Annual Meeting 2019

    Defining the SLE-Associated Pulmonary Arterial Hypertension Phenotype

    Marisa Mizus1, Jessica Li 1, Daniel Goldman 2 and Michelle Petri 1, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a leading cause of death in SLE patients. Hypocomplementemia, antiphospholipid antibodies, and elevated antibodies to RNP and Ro are…
  • Abstract Number: 2059 • ACR/ARP Annual Meeting 2019

    Usage of Predicting Out-of-Office Blood Pressure Calculator in Hispanic Patients with Rheumatic Diseases

    Dionicio Galarza-Delgado 1, Jose Azpiri-Lopez 1, Iris Colunga-Pedraza 1, Carolina Marlene Martinez-Flores1, Marielva Castro-Gonzalez 1, Ileana Cecilia Reynosa-Silva 1, Karla Paola Cuellar-Calderon 1 and Raymundo Vera-Pineda 2, 1Universidad Autonoma de Nuevo Leon, Hospital Universitario "Dr Jose Eleuterio Gonzalez", Monterrey, Nuevo Leon, Mexico, 2Universidad Autonoma de Nuevo Leon, Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Monterrey, Nuevo Leon, Mexico

    Background/Purpose: Subjects with rheumatic diseases have an increased risk of cardiovascular (CV) morbimortality. Hypertension (HTN) is a key modifiable risk factor for CV events. A…
  • Abstract Number: 2828 • ACR/ARP Annual Meeting 2019

    Implementing the BP Connect Systems-Based Blood Pressure Follow-Up Protocol with Community Rheumatology Clinic Teams

    Edmond Ramly 1, Douglas White 2, Amanda Perez 1 and Christie Bartels1, 1University of Wisconsin School of Medicine and Public Health, Madison, WI, 2Gundersen Health System, Onalaska

    Background/Purpose: Despite recognition that rheumatoid arthritis (RA) accelerates cardiovascular disease (CVD) and hypertension impacts 50% of RA patients, up to 50% lack blood pressure (BP)…
  • Abstract Number: 2243 • ACR/ARHP Annual Meeting 2018

    Sex Difference of the Association between Serum Urate and Blood Pressure in Young Adults

    Angelo Gaffo1, Elizabeth J. Rahn2, Tanja Dudenbostel1, Amy S. Mudano1, Peng Li3, David T. Redden3, Stephanie Biggers1, Phillip J. Foster2, Paul M. Muntner4, Suzanne Oparil5, David A. Calhoun5 and Kenneth Saag1, 1University of Alabama at Birmingham, Birmingham, AL, 2Department of Medicine, Division of Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, 4Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, 5Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Serum urate (sUA) has been associated with blood pressure in most but not all studies. This study aims to test whether there are sex…
  • Abstract Number: 2662 • ACR/ARHP Annual Meeting 2018

    Changes in Blood Pressure and Proteinuria at One Year in Two Lupus Nephritis Clinical Trials

    L. Michelle Gomez Mendez1, Marco Prunotto2, Jian Dai3, Paul Brakeman1, Maria Dall'Era1, Jay Garg3 and Matthew Cascino3, 1UCSF, San Francisco, CA, 2Hoffmann-La Roche, Basel, Switzerland, 3Genentech, Inc., South San Francisco, CA

    Background/Purpose: Hypertension predicts poor long-term renal outcomes for patients with lupus nephritis (LN) [1, 2]. We sought to characterize relationships between blood pressure and proteinuria…
  • Abstract Number: 301 • ACR/ARHP Annual Meeting 2018

    Rheumatology Clinic Staff Needs for Partnering to Improve Blood Pressure and Tobacco Risk Management

    Michelle Tong1, Laura Block2, Andrea Gilmore-Bykovskyi2, Edmond Ramly3 and Christie M. Bartels4, 1Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, 2University of Wisconsin School of Nursing, Madison, WI, 3Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 4Rheumatology/Medicine, University of Wisconsin - Madison, Madison, WI

    Background/Purpose: Patients with rheumatologic conditions are at a higher risk of cardiovascular disease (CVD) than peers. High blood pressure (BP) and tobacco use exacerbate CVD…
  • Abstract Number: 514 • ACR/ARHP Annual Meeting 2018

    Cardiovascular Risk Management in Seropositive Rheumatoid Arthritis: What Can We Do Better?

    Matthew McElwee1, Peter Boersma2, Hiba Hashmi3 and Anna K. Shmagel1, 1Division of Rheumatic and Autoimmune Diseases, University of Minnesota, Minneapolis, MN, 2School of Public Health, University of Minnesota, Minneapolis, MN, 3School of Medicine, University of Minnesota, Minneapolis, MN

    Background/Purpose: The increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) has been well established. While the reasons for an increased risk of CVD…
  • Abstract Number: 722 • ACR/ARHP Annual Meeting 2018

    Increased Blood Pressure Visit-to-Visit Variability in Patients with Systemic Lupus Erythematosus: Association with Inflammation, Comorbidities and Increased Mortality

    Tyler Reese1, Alyson Dickson1, Jacquelyn E. Neal2, Jocelyn S. Gandelman3, Omair A. Khan2, April Barnado4, William Dupont2, C. Michael Stein1 and Cecilia P. Chung1, 1Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 3Vanderbilt University School of Medicine, Nashville, TN, 4Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) have increased mortality compared to the general population. As outcomes related to disease control have improved, this mortality…
  • Abstract Number: 670 • ACR/ARHP Annual Meeting 2017

    Membrane Attack Complex (MAC) Deposition in Lupus Nephritis Is Associated with Hypertension and Poor Clinical Response to Treatment

    Shudan Wang1, Ming Wu2, Luis Chiriboga3, Briana Zeck4 and H. Michael Belmont5, 1Department of Medicine, Division of Rheumatology, New York University School Medicine, New York City, NY, 2New York University School of Medicine, New York, NY, 3Pathology, New York University School Medicine, New York, NY, 4Pathology, New York University School Medicine, New York City, NY, 5Medicine, New York University School of Medicine, New York, NY

    Background/Purpose: LN is characterized by deposition of immune complexes in the kidney. Activation of the classical complement pathway by dsDNA is believed to play a…
  • Abstract Number: 1088 • ACR/ARHP Annual Meeting 2017

    Staff Protocol in Rheumatology Clinics Reduces Population-Level Rate of High Blood Pressure

    Christie M. Bartels1, Edmond Ramly2, Emmanuel Sampene3, Diane Lauver4, Patrick McBride5 and Heather Johnson5, 1Rheumatology/Medicine, University of Wisconsin - Madison, Madison, WI, 2Industrial and Systems Engineering, University of Wisconsin College of Engineering, Madison, WI, 3Biostatistics, University of Wisconsin School of Medicine and Public Health, Madison, WI, 4University of Wisconsin-Madison School of Nursing, Madison, WI, 5Cardiology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI

    Background/Purpose: The Centers for Disease Control and Prevention director has said “nothing will save more lives” than protocols to control blood pressure (BP). BP is…
  • Abstract Number: 1267 • ACR/ARHP Annual Meeting 2017

    Blood Pressure Control over Time in Childhood-Onset Systemic Lupus Erythematous

    Pinar Ozge Avar Aydin1, Jian Shan2, Hermine I. Brunner1 and Mark Mitsnefes3, 1Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Peking Union Medical College Hospital, Peking, China, Peking, China, 3Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Cardiovascular disease (CVD) is the leading cause of increased long-term morbidity and mortality in systemic lupus erythematosus (SLE). As an important modifiable risk factor…
  • Abstract Number: 1558 • ACR/ARHP Annual Meeting 2017

    Changes in Blood Pressure with TNF Inhibitors for Psoriatic Arthritis

    Birju D. Bhatt1, J. Lynn Palmer2, Jeffrey R. Curtis3, Sathya Velkuru4 and Joel Kremer5, 1Medicine, div-of Rheumatology, Albany Medical College, Albany, NY, 2Corrona Research Foundation, Albany, NY, 3Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, 4Medicine, Albany Medical College, Albany, NY, 5Albany Medical College and the Center for Rheumatology, Albany, NY

    Background/Purpose:  Psoriasis is a complex disorder with cutaneous and rheumatological manifestations affecting 2-3% of the population of the Western world. The prevalence of hypertension (HTN)…
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