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Abstracts tagged "Epidemiologic methods"

  • Abstract Number: 1682 • 2019 ACR/ARP Annual Meeting

    Inpatient Epidemiology of Granulomatosis with Polyangiitis in the United States

    Patompong Ungprasert1, Matthew Koster 2, Wisit Cheungpasitporn 3, Karn Wijarnpreecha 4, Charat Thongprayoon 2 and Paul Kroner 5, 1Cleveland Clinic, Cleveland, OH, Bangkok, Thailand, 2Mayo Clinic Rochester, Rochester, MN, 3University of Mississippi Medical Center, Jackson, MS, 4Mayo Clinic Florida, Jacksonville, FL, 5Mayo Clinic Florida, Jacksonville

    Background/Purpose: Granulomatosis with polyangiitis (GPA, formerly known and Wegener’s granulomatosis) is a major subtype of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis characterized by granulomatous inflammation of…
  • Abstract Number: 1685 • 2019 ACR/ARP Annual Meeting

    Inpatient Burden, Expenditures and Comorbidities of Polyarteritis Nodosa: National Inpatient Sample 2014

    Patompong Ungprasert1, Matthew Koster 2, Wisit Cheungpasitporn 3, Karn Wijarnpreecha 4, Charat Thongprayoon 2 and Paul Kroner 5, 1Cleveland Clinic, Cleveland, OH, Bangkok, Thailand, 2Mayo Clinic Rochester, Rochester, MN, 3University of Mississippi Medical Center, Jackson, MS, 4Mayo Clinic Florida, Jacksonville, FL, 5Mayo Clinic Florida, Jacksonville

    Background/Purpose: Due to the rarity of polyarteritis nodosa (PAN), no study has ever investigated inpatient characteristics, healthcare utilization and frequency of comorbidities of patients with…
  • Abstract Number: 1890 • 2019 ACR/ARP Annual Meeting

    Methotrexate Adverse Events in a Randomized Double-Blind Placebo-Controlled Trial:Results from the Cardiovascular Inflammation Reduction Trial (CIRT)

    Daniel Solomon1, Robert Glynn 2, Elizabeth Karlson 3, Fengxin Lu 3, Cassandra Corrigan 3, Joshua Colls 3, Chang Xu 3, Jean MacFadyen 3, Medha Barbhaiya 4, Nancy Berliner 3, Paul Dellaripa 3, Brendan Everett 3, Sara Hammond 3, Meredith Murray 3, Deepak Rao 3, Susan Ritter 5, Anna Rutherford 5, Jeffrey Sparks 3, Jacklyn Stratton 5, Dong Suh 3, Sara K. Tedeschi 6, Kathleen Vanni 3, Nina Paynter 5 and Paul Ridker 5, 1Brigham and Women´s Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, 2Harvard Medical School - Boston, MA, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 5Brigham and Women's Hospital, Boston, 6Brigham and Women's Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA

    Background/Purpose: Prior observational studies have estimated the risk of adverse events with low dose methotrexate (MTX). However, prior randomized controlled trials (RCT) were too small…
  • Abstract Number: 537 • 2018 ACR/ARHP Annual Meeting

    Increased Risk of Incident Chronic Kidney Disease Among Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Cohort Studies

    Patompong Ungprasert1 and Sukit Raksasuk2, 1Clinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 2Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Increased Risk of Incident Chronic Kidney Disease among Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis of Cohort Studies AbstractBackground/Purpose: Patients with rheumatoid arthritis (RA)…
  • Abstract Number: 1611 • 2018 ACR/ARHP Annual Meeting

    Hospitalizations for Serious Infections in Psoriatic Arthritis Patients: Data from the National Inpatient Sample 2000-2014

    Paras Karmacharya1, Cynthia S. Crowson2, Dilli Poudel3, Pragya Shrestha4 and Kerry Wright5, 1Division of Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Internal Medicine, Reading Hospital-Tower Health System, WEST READING, PA, 4Internal medicine, Reading Hospital-Tower Health System, West Reading, PA, 5Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: Increased risk of infections has been recognized in patients with psoriatic arthritis (PsA) compared to those without PsA. Immunomodulatory effects of PsA, immunosuppressive therapies…
  • Abstract Number: 2857 • 2018 ACR/ARHP Annual Meeting

    An Electronic Audit, Reporting, and Data Correction System Improves the Quantity and Quality of Observational Data Collected for US Veterans Enrolled in the Veterans Affairs Rheumatoid Arthritis Registry

    Grant W. Cannon1,2, Jorge Rogas2, Neill Bell3, Joshua Baker4, Gail S. Kerr5, Angelo Gaffo6, J. Steuart Richards7, Jennifer Barton8, Pascale Schwab8, Ted R. Mikuls9, Namrata Singh10, Liron Caplan11, Deana Lazaro12, Andreas Reimold13 and Brian Sauer2, 1Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 2Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 3Salt Lake City VA Medical Center and University of Utah, Dallas VA Medical Center, Dallas, TX, 4Philadelphia VA Medical Center and University of Pennsylvania, Philadelphia, PA, 5Washington VA Medical Center, Georgetown and Howard Universities, Washington, DC, 6Birmingham VA and University of Alabama at Birmingham, Birmingham, AL, 7Pittsburgh VA Medical Center and University of Pittsburgh, Pittsburgh, PA, 8VA Portland Health Care System and Oregon Health and Science, Portland, OR, 9VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 10Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, 11Div of Rheumatology, Denver VA Medical Center and University of Colorado, Aurora, CO, 12Brooklyn VA Medical Center and SUNY Downstate, Brooklyn, NY, 13Rheumatology, Dallas VA Medical Center and University of Texas - Southwestern, Dallas, TX

    Background/Purpose:   The Veterans Affairs (VA) Rheumatoid Arthritis (RA) (VARA) registry is an observational cohort study of US Veterans with RA at 11 VA Medical…
  • Abstract Number: 640 • 2018 ACR/ARHP Annual Meeting

    Increasing Rates of Arthroplasty for Psoriatic Arthritis in the United Kingdom between 1995 and 2010

    Ryan Lewinson1, Isabelle Vallerand2, Jeremy LaMothe3, Laurie Parsons1, Alexandra Frolkis4, Mark Lowerison2, Scott Patten2 and Cheryl Barnabe2,5, 1Dermatology, University of Calgary, Calgary, AB, Canada, 2Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 3Orthopaedic Surgery, University of Calgary, Calgary, AB, Canada, 4Internal Medicine, University of Calgary, Calgary, AB, Canada, 5Division of Rheumatology, University of Calgary, Calgary, AB, Canada

    Background/Purpose: Arthroplasty requirements among patients with psoriatic arthritis (PsA) are not well known. This information is of importance to clinical and policy stakeholders for health…
  • Abstract Number: 2144 • 2018 ACR/ARHP Annual Meeting

    Epidemiological Characterisitics of Psoriatric Arthritis: A Nationwide Study of Inpatient Hospitalisations in 2014

    Vagishwari Murugesan and Jennifer Tran, Internal Medicine, Medstar Washington Hospital Center, Washington, DC

    Background/Purpose:: Psoriatic arthritis is a seronegative inflammatory arthritis associated with Psoriasis. Using the National Inpatient Sample (NIS) we studied the epidemiological characteristics of inpatients admissions…
  • Abstract Number: 2896 • 2018 ACR/ARHP Annual Meeting

    Increased Mortality Among Patients with Systemic Lupus Erythematosus after Hydroxychloroquine Discontinuation

    April Jorge1, Na Lu2,3, Eric C. Sayre3, Hamid Tavakoli4, Natalie McCormick5, John M. Esdaile3,6, Mary DeVera5, Hyon K. Choi1 and J. Antonio Avina-Zubieta7, 1Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Arthritis Research Canada, Richmond, BC, Canada, 4Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, 5Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, 6Department of Medicine, Division of Rheumatology, University of British Columbia, Vancouver, BC, Canada, 7Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: Hydroxychloroquine (HCQ) is near-universally recommended for patients with SLE. Use of this medication has previously been associated with a substantial survival benefit among SLE…
  • Abstract Number: 673 • 2018 ACR/ARHP Annual Meeting

    Chronic Back Pain (CBP) in First Degree Relatives (FDRs) of Patient with Ankylosing Spondylitis (AS): Comparison with the US Population, HLA-B27 Frequency and Persistence of Symptoms over Time

    John D. Reveille1, MinJae Lee2, Laura A. Diekman3, Michael Ward4, Lianne S. Gensler5, Amirali Tahanan2, Mohammad H. Rahbar6 and Michael Weisman7, 1McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, 2Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas-McGovern Medical School, Houston, TX, 3Rheumatology, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, 4National Institutes of Health, Bethesda, MD, USA, Bethesda, MD, 5University of California San Francisco, San Francisco, CA, 6Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, 7Harbor UCLA Medical Center, Los Angeles, CA

    Background/Purpose: We examined first degree relatives (FDRs) of patients with ankylosing spondylitis (AS) patients with chronic inflammatory back pain (CIBP), non-inflammatory CBP (NICBP) and no…
  • Abstract Number: 2145 • 2018 ACR/ARHP Annual Meeting

    Increased Risk of Heart Failure with Prolonged Use of Hydroxychloroquine in Patients with Rheumatoid Arthritis

    Elena Myasoedova1, Reto Kurmann2, Cynthia S. Crowson3, John M. Davis III1 and Rekha Mankad2, 1Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, 2Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN

    Background/Purpose: Hydroxychloroquine (HCQ) is commonly prescribed for patients with rheumatoid arthritis (RA). Cardiotoxicity is a rare but potentially life-threatening side effect of HCQ and may…
  • Abstract Number: 2924 • 2018 ACR/ARHP Annual Meeting

    Spinal Radiographic Progression in Early Axial Spondyloarthritis: 5-Year Data from the DESIR Cohort

    Sofia Ramiro1, Désirée van der Heijde2, Alexandre Sepriano3, Miranda van Lunteren4, Anna Molto5, Maria Antonietta D'Agostino6, Damien Loeuille7, Maxime Dougados8, M. Reijnierse9 and Pascal Claudepierre10, 1Zuyderland Medical Center, Heerlen & Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Centre, Leiden, Netherlands, 3Leiden University Medical Center, Leiden, Netherlands, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, 6Department of Rheumatology, Assistance publique-Hôpitaux de Paris Ambroise Paré Hospital, Boulogne-Billancourt , Université Versailles Saint Quentin en Yvelines, Paris, France, 7Rheumatology, University Hospital of Nancy, NANCY, France, 8Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, 9Radiology, Leiden University Medical Center, Leiden, Netherlands, 10Hôpital Henri Mondor, Créteil, France

    Background/Purpose: Spinal radiographic progression has been investigated in patients with r-axSpA, but not yet as thoroughly in early axSpA. We aimed to analyse the progression…
  • Abstract Number: 941 • 2018 ACR/ARHP Annual Meeting

    Causal Inference Methods for the Effect of Rheumatoid Arthritis on Mortality Independent of Lifestyle and Clinical Factors before and after RA Diagnosis

    Jeffrey A. Sparks1, Kazuki Yoshida1,2, Tzu-Chieh Lin3, Carlos Camargo4, Benjamin Raby5, Hyon K. Choi6, Medha Barbhaiya7, Sara K. Tedeschi1, Bing Lu8, Karen Costenbader1 and Elizabeth Karlson1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Harvard T.H. Chan School of Public Health, Boston, MA, 3Amgen, Thousand Oaks, CA, 4Emergency Medicine, Massachusetts General Hospital, Boston, MA, 5Pulmonary, Brigham and Women's Hospital, Boston, MA, 6Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 7Rheumatology, Hospital for Special Surgery, New York, NY, 8Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: RA is associated with increased total, cardiovascular, and respiratory mortality compared to the general population. This excess RA mortality may be mediated through lifestyle,…
  • Abstract Number: 2149 • 2018 ACR/ARHP Annual Meeting

    Assessing the Prevalence of Localized Scleroderma in Childhood Using Dministrative Claims Data from the United States

    Timothy Beukelman1, Fenglong Xie2 and Ivan Foeldvari3, 1Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany

    Background/Purpose: Juvenile Localised Scleroderma (jlSc) is believed a rare autoimmune disease, which occurs 10 times more often then systemic sclerosis in childhood and is believed…
  • Abstract Number: 2952 • 2018 ACR/ARHP Annual Meeting

    Major NSAID Toxicity: Derivation and Internal Validation of a Simple Clinical Risk Score

    Daniel Solomon1, Ming Shao2, Katherine E Wolski3, Steven E Nissen4, M. Elaine Husni5 and Nina Paynter6, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Cleveland Clinic Foundation, Cleveland, OH, 3Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, 4Cardiovascular Medicine, Chair, Cleveland Clinic, Cleveland, OH, 5Orthopedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH, 6Medicine, Harvard University, Boston, MA

    Background/Purpose: NSAIDs and Coxibs represent one of the most commonly prescribed drugs by rheumatologists and are used regularly by >10 million Americans. While most patients…
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