Abstracts tagged "Environmental factors"

Abstract Number: 1800 • ACR Convergence 2020
Association of Air Pollution with Systemic Lupus Erythematosus Disease Activity in the Central Valley of California
Mosaab Mohameden¹, Ali H.Ali², Zi Ying Li², Yabsira Abejie³, Ratnali Jain² and Candice Reyes Yuvienco⁴, ¹University of Cincinnati College of Medicine, Cincinnati, OH, ²University of California San Francisco Fresno, Fresno, CA, ³Floyd B. Buchanan High School, Fresno, CA, ⁴University of California San Francisco Fresno, Clovis, CA
Background/Purpose: Systemic lupus erythematosus (SLE) is a complex multisystem autoimmune disease that affects at least 300,000 people in the United States creating a substantial socioeconomic…
Abstract Number: 1813 • ACR Convergence 2020
A Comprehensive Method to Study Environmental Chemicals in Serum in Patients with SLE
Cristina Lanata¹, Kim Taylor², James Hurst-Hopf¹, Laura Trupin¹, Patricia Katz³, Jinoos Yazdany¹, Maria Dall'Era⁴, Dimitri Abrahamsson¹, Lindsey Criswell⁵ and Roy Gerona¹, ¹UCSF, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA, ³University of California, San Francisco, Novato, CA, ⁴Division of Rheumatology, University of California, San Francisco, CA, ⁵Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California San Francisco, San Francisco, CA
Background/Purpose: Environmental exposures may play a substantial role in the pathogenesis of Systemic Lupus Erythematosus (SLE), however it has been challenging to measure and capture…
Abstract Number: 2037 • ACR Convergence 2020
Geographic Distribution and Environmental Triggers of Systemic Sclerosis in Massachusetts
Anastasiya Muntyanu¹, Bina Kassamali², Ruth Ann Vleugels³ and Avery LaChance³, ¹McGill University, Montreal, QC, Canada, ²Harvard Medical School, Brigham and Women's Hospital, Boston, MA, ³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Systemic sclerosis (SSc) is a chronic autoimmune sclerosing disease with a 10-year survival rate of less than 65%. This rate has remained unchanged for…
Abstract Number: 0086 • ACR Convergence 2020
Geographic Distribution of Eosinophilic Fasciitis Cases in Massachusetts and Associated Environmental Triggers
Bina Kassamali¹, Anastasiya Muntyanu², Ruth Ann Vleugels³ and Avery LaChance³, ¹Harvard Medical School, Brigham and Women's Hospital, Boston, MA, ²McGill University, Montreal, QC, Canada, ³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Eosinophilic fasciitis (EF) is a rare fibrosing disorder of the fascia characterized by induration progressing proximally along the upper and lower extremities. Given the…
Abstract Number: 187 • 2019 ACR/ARP Annual Meeting
Epidemiology of JIA-Associated Uveitis: Environmental Factors and Disease Characteristics of a JIA-Associated Uveitis Cohort
Theresa Hennard ¹, Najima Mwase ², Amy Cassedy ³, Joseph McDonald ⁴, Virginia Utz ⁵ and Sheila Angeles-Han⁶, ¹Division of Rheumatology, Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, ²Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁴Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁵Division of Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cinicinnati
Background/Purpose: JIA-associated uveitis (JIA-U) is the most prevalent extra-articular manifestation of JIA and the most common type of uveitis in children. To date, environmental factors…
Abstract Number: 693 • 2019 ACR/ARP Annual Meeting
Hair Chemicals and Systemic Lupus Erythematosus: A Case-Control Study
Jessica English¹, Trevor Faith ², Dulaney Wilson ¹ and Diane Kamen ³, ¹Medical University of South Carolina, Charleston, SC, ²Medical University of South Carolina, Charleston, ³Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA., Charleston, SC
Background/Purpose: Systemic lupus erythematosus (SLE) is a complex chronic autoimmune disease of unknown etiology. Previous studies of beauty products as potential triggers of SLE development…
Abstract Number: 1106 • 2019 ACR/ARP Annual Meeting
Systemic Lupus Erythematosus and Sjögren’s Syndrome in the Agricultural Health Study: Lower Risk Associated with Childhood Farm Residence and Raising Livestock
Christine Parks¹, Stuart Long ², Laura Beane-Freeman ³, Hofmann Jonathan ³ and Sandler Dale ¹, ¹National Institute of Environmental Health Sciences, Research Triangle Park, ²Westat, Research Triangle Park, NC, ³National Cancer Institute, Bethesda
Background/Purpose: Prior research suggests that growing up on a farm and contact with livestock may confer protection against developing systemic autoimmune diseases, such as rheumatoid…
Abstract Number: 2084 • 2019 ACR/ARP Annual Meeting
Why so Fast? A Focus on Reasons for an Increase in Arthritis-Attributable Activity Limitation Trends, 2002-2017
Kristina Theis¹, Michael Boring ² and Ross Wilkie ³, ¹Centers for Disease Control and Prevention, Atlanta, ²Johnson Consulting dba Cutting Edge Technologies and Solutions, Atlanta, ³Keele University, Keele, United Kingdom
Background/Purpose: “Arthritis-attributable activity limitation” (AAAL) is linked to many potentially modifiable characteristics (e.g., work disability, physical inactivity, obesity). By 2015, prevalence of AAAL among adults…
Abstract Number: 69 • 2018 ACR/ARHP Annual Meeting
Possible Association of Early Inflammatory Arthritis with Viral Outbreaks Such As Influenza: Time Series Analysis of the Canadian Early Inflammatory Arthritis Cohort
Fatima Kudaeva¹, Mark Speechley², Neil Klar², Orit Schieir³, Susan J. Bartlett⁴, Louis Bessette⁵, Gilles Boire⁶, Glen Hazlewood⁷, Carol A Hitchon⁸, Edward C. Keystone⁹, Diane Tin¹⁰, Carter Thorne¹¹, Vivian P. Bykerk¹² and Janet E. Pope¹³, ¹Department of Epidemiology & Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, ²Epidemiology & Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, ³Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ⁴Department of Medicine, Division of ClinEpi, Rheumatology, Respirology, McGill University, Montreal, QC, Canada, ⁵Division of Rheumatology, Department of Medicine, CHU de Québec-Université Laval, Québec, QC, Canada, ⁶Rheumatology Division, Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁷Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada, ⁸University of Manitoba, Winnipeg, MB, Canada, ⁹University of Toronto and Mount Sinai Hospital, Toronto, ON, Canada, ¹⁰The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹University of Toronto, Newmarket, ON, Canada, ¹²Hospital for Special Surgery, New York, NY, ¹³Department of Medicine, University of Western Ontario, London, ON, Canada
Background/Purpose: Disease clustering suggests a possible environmental cause. Rheumatoid arthritis (RA) is an autoimmune disease that may be triggered by environmental factors such as viruses.…
Abstract Number: 89 • 2018 ACR/ARHP Annual Meeting
Anti-Nuclear Antibodies (ANA) and Air Pollution: Ultrafine Particles and Ozone
Sasha Bernatsky¹, Shouao Wang², May Y Choi³, Scott Weichenthal⁴, Marianne Hatzopoulou⁵, Marvin J. Fritzler⁶ and Audrey Smargiassi⁷, ¹Divisions of Rheumatology and Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ²Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁴Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada, ⁵Civil and Mineral Engineering, University of Toronto, Toronto, ON, Canada, ⁶Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁷Public Health, Université de Montreal, Montreal, QC, Canada
Background/Purpose: Previous studies have suggested links between air pollution (particularly PM2.5) and serum antibodies related to rheumatic diseases. No one has yet examined anti-nuclear antibody…
Abstract Number: 201 • 2018 ACR/ARHP Annual Meeting
Occupational Exposure to Coal and Silica Dust Is Associated with Elevated Risk of Rheumatoid Arthritis in Coal Mining Areas of US
Laura Trupin¹, Edward H. Yelin², Gabriela Schmajuk³ and Paul Blanc⁴, ¹University of California San Francisco, San Francisco, CA, ²Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ³San Francisco VA Medical Center, San Francisco, CA, ⁴Medicine, University of California San Francisco, San Francisco, CA
Background/Purpose: Exposure to inhaled mineral dust, particularly silica, has been associated with increased risk of RA and other autoimmune diseases. Coal mining leads to silica…
Abstract Number: 482 • 2018 ACR/ARHP Annual Meeting
The Association of Short-Term Ultraviolet Radiation Exposure and Calcinosis in Juvenile Dermatomyositis in the Childhood Arthritis & Rheumatology Research Alliance Registry
Jessica Neely¹, Craig S. Long², Hugh Sturrock³ and Susan Kim⁴, ¹Pediatric Rheumatology, University of California, San Francisco, San Francisco, CA, ²National Oceanic and Atmospheric Administration (NOAA)/Climate Prediction Center, College Park, MD, ³Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁴Pediatric Rheumatology, University of California, San francisco School of Medicine, San Francisco, CA
Background/Purpose: JDM is an autoimmune systemic vasculopathy characterized by myositis and skin rash. Some myositis specific antibodies (MSAs) are associated with clinical manifestations in JDM,…
Abstract Number: 1087 • 2018 ACR/ARHP Annual Meeting
Association between Cigarette Smoking and Systemic Lupus Erythematosus – a Bayesian Multivariate Meta-Analysis of Case-Control and Cohort Studies
Monica Hui Yan Chua¹, Irene Ai Ting Ng¹, Mike Wai-Leung Cheung² and Anselm Mak³, ¹Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, ²Psychology, Faculty of Arts and Social Sciences, National University of Singapore, Singapore, Singapore, ³Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
Background/Purpose: The association between cigarette smoking and the occurrence of SLE has been studied over the past two decades but results are conflicting. The global…
Abstract Number: 132 • 2017 ACR/ARHP Annual Meeting
Occupational Physical Workload and Development of Anti-Collagen Type II Antibodies in Rheumatoid Arthritis Patients
Pingling Zeng¹, Lars Alfredsson², Lars Klareskog³, Mohammed Mullazehi⁴, Saedis Saevarsdottir⁵, Camilla Bengtsson⁶ and Johan Rönnelid⁷, ¹Institute of Environmental Medicine, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden, Stockholm, Sweden, ²The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ³Dept. of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, ⁴Department of Immunology, Genetics and Pathology,Uppsala University, Uppsala, Sweden, Uppsala, Sweden, ⁵Karolinska Institute and Karonlinska University Hospital, Stockholm, Sweden, ⁶Inst of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁷Department of Immunology Genetics and Pathology, Uppsala University, Uppsala, Sweden
Background/Purpose: We have previously observed an association between exposure to occupational physical workload (PW) and risk of developing rheumatoid arthritis (RA)[1].We posit that PW could…
Abstract Number: 914 • 2017 ACR/ARHP Annual Meeting
Occupational Exposure to Combustion Products and Risk of Developing Rheumatoid Arthritis
Anna Ilar¹, Pernilla Wiebert^1,2, Saedis Saevarsdottir³, Johan Askling^4,5, Per Gustavsson^1,2 and Lars Alfredsson^1,2, ¹The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ²Stockholm County Council, Centre for Occupational and Environmental Medicine, Stockholm, Sweden, ³Rheumatology Unit, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁴Rheumatology unit, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁵Unit of Clinical Epidemiology, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Studies have suggested a potential association between traffic pollutants and rheumatoid arthritis (RA), but findings have been inconclusive. We therefore assessed the risk of…

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