Abstracts tagged "Arthritis"

Abstract Number: 1236 • 2018 ACR/ARHP Annual Meeting
Peripheral-Blood B-Cell Subset Disturbances in Whipple’s Disease
Maelle Le Goff¹, Divi Cornec², Dewi Guellec¹, Thierry Marhadour¹, Valérie Devauchelle-Pensec¹, Sandrine Jousse-Joulin¹, Marion Herbette¹, Jean-Michel Cauvin³, Clara Le Guillou³, Yves Renaudineau⁴, Jacques-Olivier Pers⁵ and Alain Saraux¹, ¹Rheumatology, CHU Brest, Brest, France, ²Rheumatology and UMR1227, Lymphocytes B et Autoimmunité, CHU Brest, Brest, France, ³CDC, CHU Brest, Brest, France, ⁴U1227, Université de Brest, inserm, Labex IGO, CHU de brest, Brest, France, ⁵U1227, Université de Brest, Inserm, Labex IGO, CHU de Brest, Brest, France
Background/Purpose: Whipple’s disease (WD) is a rare, systemic, disease caused by the intracellular Gram-positive bacterium Tropheryma whipplei (TW). This ubiquitous commensal organism is transmitted among…
Abstract Number: 2943 • 2018 ACR/ARHP Annual Meeting
Helping a Non-Urban Community Walk with Ease: A Feasibility Pilot Study of an Arthritis Activity Intervention
Amanda Perez¹, Brock Polnaszek², Douglas White³, Lee Walraven⁴, Chelsea Barnes⁴ and Christie M. Bartels¹, ¹Rheumatology/Medicine, University of Wisconsin - Madison, Madison, WI, ²Obstetrics and Gynecology, Washington University, St. Louis, MO, ³Gundersen Lutheran - Onalaska Clinic, Onalaska, WI, ⁴La Crosse Area Family YMCA, La Crosse, WI
Background/Purpose: An estimated 54 million US adults have arthritis, and more than half are not receiving the recommended physical activity (MMWR, 2018). Walk With Ease…
Abstract Number: 136 • 2018 ACR/ARHP Annual Meeting
Alpn-101, a Dual ICOS/CD28 Antagonist, Potently Suppresses Disease in Multiple Mouse Models of Autoimmunity
Stacey Dillon¹, Katherine Lewis¹, Lawrence Evans², Ryan Swanson², Jing Yang³, Martin Wolfson⁴, Michelle Seaberg¹, Kayla Susmilch⁵, Sherri Mudri¹, Mark Rixon⁴, Stanford Peng⁶ and Kristine Swiderek⁷, ¹Translational Sciences, Alpine Immune Sciences, Seattle, WA, ²Immunology, Alpine Immune Sciences, Seattle, WA, ³Clinical, R&D, Alpine Immune Sciences, SEATTLE, WA, ⁴Protein Therapeutics, Alpine Immune Sciences, Seattle, WA, ⁵Translational Sciences, Alpine Immune Sciences, SEATTLE, WA, ⁶Clinical, R&D, Alpine Immune Sciences, Seattle, WA, ⁷Research, Alpine Immune Sciences, SEATTLE, WA
Background/Purpose: CD28 and Inducible T-cell Costimulator (ICOS) are two related costimulatory molecules within the immunoglobulin superfamily (IgSF) expressed on T cells and interacting with CD80/CD86…
Abstract Number: 1237 • 2018 ACR/ARHP Annual Meeting
What Is the Value of Synovial Biopsies for the Diagnosis of Septic Arthritis?
Bastien Ouvrard^1,2, Géraldine Bart¹, Christelle Darrieutort¹, Aurélie Najm¹ and Benoit Le Goff¹, ¹CHU Nantes, Nantes, France, ²INSERM UMR1238, nantes, France
Background/Purpose: Synovial biopsies are increasingly performed for research purposes but also in clinical practice. The development of US guided procedure has made this procedure simpler.…
Abstract Number: 2972 • 2018 ACR/ARHP Annual Meeting
Multicentric Reticulohistiocytosis (1980-2017): A Rare Disease, Commonly Associated with Malignancy and Autoimmunity
Avneek Singh Sandhu¹, Cynthia S. Crowson², David Wetter³, Gavin McKenzie⁴ and Ashima Makol¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Dermatology, Mayo Clinic, Rochester, MN, ⁴Radiology, Mayo Clinic, Rochester, MN
Background/Purpose: Multicentric reticulohistiocytosis (MRH) is a systemic disease characterized by papulo-nodular skin eruptions and progressive, deforming arthritis. We aimed to examine the clinical correlates and…
Abstract Number: 359 • 2018 ACR/ARHP Annual Meeting
Characterization of Lymphoid Cells in Synovial Fluid from Cancer Patients with Immunotherapy-Induced Arthritis
Sang Kim¹, Jean Tayar¹, Huifang Lu¹, Jennifer Wang², Don Gibbons³, Guillermo Garcia-Manero⁴, Patrick Hwu⁵, Adi Diab⁵ and Roza Nurieva⁶, ¹General Internal Medicine (Rheumatology), MD Anderson Cancer Center, Houston, TX, ²Genitourinary Medical Oncology, MD Anderson Cancer Center, Houston, TX, ³Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, Houston, TX, ⁴Leukemia, MD Anderson Cancer Center, Houston, TX, ⁵Melanoma Medical Oncology, MD Anderson Cancer Center, Houston, TX, ⁶Immunology, MD Anderson Cancer Center, Houston, TX
Background/Purpose: Checkpoint inhibitors (ICIs) are revolutionizing cancer treatment; however, ICI therapy is associated with immune-related adverse events (irAEs). irAEs can be life-threatening and/or severely impair…
Abstract Number: 1267 • 2018 ACR/ARHP Annual Meeting
The Association between Clinically Suspect Arthralgia and Adipokines in Obese Patients
Taskin Senturk¹, Reyhan Kose¹, Gokhan Sargin¹, Songul Cildag², Mustafa Unubol³, Burçin İrem Abas⁴ and Cigdem Yenisey⁴, ¹Rheumatology, Adnan Menderes University Medical School, Aydin, Turkey, ²Allergy and Immunology, Adnan Menderes University Medical School, Aydin, Turkey, ³Endocrinology and Metabolism, Adnan Menderes University Medical School, Aydin, Turkey, ⁴Biochemistry, Adnan Menderes University Medical School, Aydin, Turkey
Background/Purpose: Obesity is a moderate low-grade chronic inflammatory condition. Also, it has been reported to be a risk factor for inflammatory rheumatic diseases, seronegative inflammatory…
Abstract Number: 375 • 2018 ACR/ARHP Annual Meeting
Only a Minor Proportion of Individuals with Anti-Aminoacyl-tRNA Synthetase Autoimmunity Presents with the Clinical Picture of “Antisynthetase-Syndrome”
Johannes Knitza, Hannah Schenker, Georg Schett and Jörg Distler, Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Antisynthetase Syndrome is a rare and severe autoimmune inflammatory disease that is associated with autoimmunity against aminoacyl-tRNA synthetase and clinical signs of arthritis, myositis…
Abstract Number: 1448 • 2018 ACR/ARHP Annual Meeting
Clinical Impact of Articular Ultrasound in Diagnosis and Follow-up of Patients with Polyarthritis
Justine Lafleur-Careau¹, François Taschereau¹, Artur J de Brum-Fernandes², Alessandra Bruns³, Gilles Boire⁴ and Ariel Masetto⁵, ¹Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada, ²Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada, ³Rhumatologie, Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Rheumatology Division, Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁵Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, AB, Canada
Background/Purpose: It is well established in the literature that musculoskeletal ultrasound (MSUS) is more sensitive than clinical examination in the detection of synovitis. MSUS can…
Abstract Number: 664 • 2018 ACR/ARHP Annual Meeting
Prevalence and Factors Associated with Peripheral Manifestations in Spondyloarthritis. an Ancillary Analysis of the ASAS-Comospa Study
Clementina López-Medina¹, Anna Molto² and Maxime Dougados³, ¹Rheumatology Department, Cochin Hospital, Paris, France, ²Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ³Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France
Background/Purpose: Peripheral manifestations (arthritis, enthesitis and dactylitis) can be observed in patients with Spondyloarthritis (SpA), but the factors associated with their presence are not well…
Abstract Number: 1475 • 2018 ACR/ARHP Annual Meeting
Eicosanoid Mediators of Systemic Inflammation and Arthritis in the Elderly
Roxana Coras^1,2, Rekha Narasimhan¹, Arthur Kavanaugh³, Lourdes Mateo⁴, Oswald Quehenberger⁵, Melania Martinez-Morillo⁶ and Monica Guma^1,2, ¹Medicine, University of California San Diego, La Jolla, CA, ²Medicine, Autonomous University of Barcelona, Bellatera, Spain, ³University of California, San Diego, School of Medicine, La Jolla, CA, ⁴Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ⁵Pharmacology, Medicine, University of California San Diego, La Jolla, CA, ⁶Rheumatology, Germans Trias i Pujol University Hospital, Barcelona, Spain
Background/Purpose: Elderly-onset RA, EORA, which is defined as rheumatoid arthritis (RA) starting at >60 years of age, has received less attention than young-onset RA. Polymyalgia rheumatica (PMR) is…
Abstract Number: 679 • 2018 ACR/ARHP Annual Meeting
Ultrasonographic Research of the Relationship between Nail Disorders and Peripheral Arthritis or Enthesitis in Patients with Psoriasis and Psoriatic Arthritis
Tadashi Okano¹, Kentaro Inui², Koji Mandai³, Yutaro Yamada⁴, Tatsuya Koike⁵ and Hiroaki Nakamura², ¹Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ³Orthopaedic surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ⁴Orthopedic surgery, Yodogawa Christian Hospital, Osaka, Japan, ⁵Center for Senile Degenerative Disorders, Osaka City University Graduate School of Medicine, Osaka, Japan
Background/Purpose: Although skin lesion is the most typical findings in patients with psoriasis (PsO), nail psoriasis is also one of the important clinical manifestation. Moreover,…
Abstract Number: 1493 • 2018 ACR/ARHP Annual Meeting
Clinical Predictor Factors Associated with Sustained Disease Activity Among Patients with Early Rheumatoid Arthritis
Gabriela Gonzalez and Juan Molina, Rheumatology, La Paz University Hospital, Madrid, Spain
Background/Purpose: in rheumatoid arthritis (RA) patients the disease outcome has an unpredictable course and may differ even with an early diagnosis and treatment. Low disease…
Abstract Number: 760 • 2018 ACR/ARHP Annual Meeting
Diagnosing SLE Arthritis with Dynamic Diffuse Optical Spectroscopy
George Danias¹, Youngwan Kim², Alessandro Marone³, Kayla Neville¹, Andrea Frantz¹, Teja Kapoor⁴, Laura Geraldino-Pardilla¹, Ioannis Kymissis², Andreas Hielscher^2,3,5 and Anca Askanase¹, ¹Rheumatology, Columbia University Medical Center, New York, NY, ²Electrical Engineering, Columbia University, New York, NY, ³Biomedical Engineering, Columbia University, New York, NY, ⁴Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ⁵Radiology, Columbia University Medical Center, New York, NY
Background/Purpose: SLE arthritis is difficult to evaluate because of the sometimes-evanescent nature of the symptoms and limitations of physical exams and imaging studies. Dynamic diffuse…
Abstract Number: 1660 • 2018 ACR/ARHP Annual Meeting
Depression Has a Greater Impact on Psoriatic Arthritis Than Rheumatoid Arthritis
Surjeet Dheer¹, Vivekanand Tiwari², Ammarah Hussain¹, Kakageldi Hommadov¹, Ana Maheshwari¹ and Martin J. Bergman³, ¹Mercy Catholic Medical Center, Philadelphia, PA, ²St John's Hospital, Springfield, IL, ³Drexel University College of Medicine, Philadelphia, PA
Background/Purpose: Depression has been shown to be more common in patients with psoriatic arthritis (PsA) and rheumatoid arthritis (RA), than in the general population. The…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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