ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 1457

Two Minute Walking Distance and Other Timed Function Tests Are Superior to MMT-8 in Assessing Outcomes in Polymyositis and Dermatomyositis

Sai kumar Dunga1, Chengappa G Kavadichanda2 and VS Negi2, 1Jawaharlal institute of postgraduate medical education and research, puducherry, India, 2Jawaharlal institute of postgraduate medical education and research, Puducherry, Puducherry, India

Meeting: ACR Convergence 2020

Keywords: functional status, Muscle Function, Myositis, Outcome measures, Patient reported outcomes

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print
Session Information

Date: Sunday, November 8, 2020

Title: Clinical Practice II (1457–1461)

Session Type: Abstract Session

Session Time: 10:00AM-10:50AM

Background/Purpose: Inflammatory myositis are heterogenous group of diseases affecting skeletal muscles and multiple different organs. Assessing improvement in disease activity is done by Manual muscle testing (MMT) and Functional index 2(FI-2). These are time taking and need expertise to administer. Several Timed function tests (TFTs) like the 2- minute walk test (2MWT) or 30s raise from a chair test and 30s 1kg arm rise test may be better alternatives and less time taking. Moreover these tests can be self-administered by patients themselves. In the current world of accountability for treatment response and improvement in technology, these TFTs upon self-administration in particular time intervals have the potential to provide objective data on diseases status enabling the physician to make therapeutic decisions. We undertook a study with objective to evaluate the performance of TFT in assessing muscle diseases at baseline and to evaluate the performance of TFTs to detect change in muscle power and endurance with treatment.

Methods: This is an observational cohort study which included 29 patients with polymyositis and dermatomyositis satisfying ENMC classification criteria. Patients with inclusion body myositis, overlap myositis, chronic kidney disease, coexisting myocarditis, sepsis, malignancy, pregnancy were excluded. MMT8, FI-, EQ-5D and Timed function tests were done at baseline and after 3 months.  

Results: The study had 29 patients of which 6 were polymyositis and 23 were dermatomyositis. Male to female ratio was 1:2.1. Anti-cell antibody was positive in 20 patients. Out of 29 patients, 11 had active disease and rest 18 had stable disease. Mean scores of MMT8, Fi-2 and TFTs are shown in table 1. The 3 TFTs had moderate to high correlation with MMT8 and FI-2 at baseline in inactive disease group but only with FI-2 in active disease as shown in Table 2. At 3 months, change in all 3 TFTs significantly correlated with change in Fi-2 in active disease, but in stable disease only 2MWD had moderate correlation with MMT8. (Table 3)

Conclusion: 2 Minute walk distance is a better alternative to the conventional muscle testing as it measures both power and endurance. This score can overcome the ceiling effect of MMT-8. Besides, owing to the ease of administration 2MWD may be used as a patient reported outcome measure in IIM.


Disclosure: S. Dunga, None; C. Kavadichanda, None; V. Negi, None.

To cite this abstract in AMA style:

Dunga S, Kavadichanda C, Negi V. Two Minute Walking Distance and Other Timed Function Tests Are Superior to MMT-8 in Assessing Outcomes in Polymyositis and Dermatomyositis [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/two-minute-walking-distance-and-other-timed-function-tests-are-superior-to-mmt-8-in-assessing-outcomes-in-polymyositis-and-dermatomyositis/. Accessed .
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to ACR Convergence 2020

ACR Meeting Abstracts - https://acrabstracts.org/abstract/two-minute-walking-distance-and-other-timed-function-tests-are-superior-to-mmt-8-in-assessing-outcomes-in-polymyositis-and-dermatomyositis/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology