Abstracts tagged "Outcome measures"

Abstract Number: 481 • 2018 ACR/ARHP Annual Meeting
Stepping It up: The Use of Physical Activity Monitors As an Outcome Measure in Juvenile Myositis
Emily Brunner¹, Laura Tasan², Kathryn S. Torok³, Bonny Rockette-Wagner⁴, Christina K. Zigler⁵, Kaila Schollaert-Fitch³, Diane Koontz⁶, Chester V. Oddis⁷ and Rohit Aggarwal⁸, ¹Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ³Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA, ⁵Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA, ⁶Internal Medicine Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁷Division of Rheumatology and Clinical Immunology, Department of Medicine, Unviersity of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA, ⁸Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA
Background/Purpose: The use of physical activity monitors (PAM), which objectively quantify free-living movement, may enhance assessment of disease activity in juvenile myositis (JM) clinical trials…
Abstract Number: 2687 • 2018 ACR/ARHP Annual Meeting
Patient-Level Evaluation of Components of the American College of Rheumatology Combined Response Index in Systemic Sclerosis (CRISS) Using Patient-Reported Anchors
Vivek Nagaraja¹, John Powers², Celia J. F. Lin³, Benjamin Brennan⁴, Veronica J. Berrocal⁵ and Dinesh Khanna¹, ¹Division of Rheumatology, Department of Internal Medicine, University of Michigan Scleroderma Program, University of Michigan, Ann Arbor, MI, ²University of Maryland School of Medicine, Rockville, MD, ³Genentech, Inc., South San Francisco, CA, ⁴School of Public Health, University of Michigan, Ann Arbor, MI, ⁵Div of Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: Treatment benefit is demonstrated by evidence that interventions have positive impacts on how patients feel, function, and/or survive (FDA Guidance, 21CFR314.510). The ACR CRISS,…
Abstract Number: 681 • 2018 ACR/ARHP Annual Meeting
Identification of Treatment Naïve Patients with Psoriatic Arthritis Who Will Require a TNF Inhibitor
Dan Gromer¹, Laura C. Coates², Oliver FitzGerald³, Blanca Himes⁴, Philip Helliwell⁵ and Alexis Ogdie⁶, ¹University of Pennsylvania, Medical Student, Philadelphia, PA, ²University of Oxford, Oxford, United Kingdom, ³Department of Rheumatology, St Vincent's University Hospital and Conway Institute, University College Dublin, Ireland, Dublin, Ireland, ⁴Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ⁵LIMM, Section of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, ⁶Medicine/Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous chronic inflammatory disease that affects the skin, joints, and soft tissues. No metrics exist to indicate whether an…
Abstract Number: 2783 • 2018 ACR/ARHP Annual Meeting
EULAR Task Force Recommendations for a Minimum Core Set of Parameters to be Collected in Giant Cell Arteritis Registries and Databases
Lisa Ehlers¹, Johan Askling², Johannes W. J. Bijlsma³, Maria C. Cid⁴, Maurizio Cutolo⁵, Bhaskar Dasgupta⁶, Christian Dejaco^7,8, William G Dixon⁹, Nils Feltelius^10,11, Axel Finckh¹², Kate Gilbert¹³, Sarah Mackie¹⁴, Alfred Mahr¹⁵, Eric L. Matteson¹⁶, Lorna Neill¹⁷, Carlo Salvarani^18,19, Wolfgang A. Schmidt²⁰, Anja Strangfeld²¹, Ronald van Vollenhoven²² and Frank Buttgereit¹, ¹Department of Rheumatology and Clinical Immunology, Charité University Hospital Berlin, Berlin, Germany, ²Unit of Clinical Epidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ³Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ⁴University of Barcelona, Barcelona, Spain, ⁵Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, ⁶Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, United Kingdom, ⁷Department of Rheumatology and Immunology, Medical University Graz, Graz, Austria, Graz, Austria, ⁸Rheumatology, Hospital of Bruneck, Bruneck, Italy, ⁹Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, ¹⁰Medical Products Agency, Uppsala, Sweden, ¹¹Cross-Committee Task Force on Registries at the European Medicines Agency, London, United Kingdom, ¹²University Hospital of Geneva, Geneva, Switzerland, ¹³Patient Representative from PMRGCAuk, London, United Kingdom, ¹⁴NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, University of Leeds, Leeds, United Kingdom, ¹⁵Internal Medicine, Saint-Louis Hospital, Paris Diderot University, Paris, France, ¹⁶Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, ¹⁷Patient Representative from PMR-GCA Scotland, Perth, United Kingdom, ¹⁸Università di Modena e Reggio Emilia, Modena, Italy, ¹⁹Azienda USL-IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy, ²⁰Medical Center for Rheumatology and Clinical Immunology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, ²¹Epidemiology, German Rheumatism Research Center, Berlin, Germany, ²²Amsterdam Rheumatology and Immunology Center ARC, Amsterdam, Netherlands
Background/Purpose: Giant cell arteritis (GCA) represents the most common form of primary systemic vasculitis, and is frequently associated with comorbidities related either to the disease…
Abstract Number: 723 • 2018 ACR/ARHP Annual Meeting
Patient-Reported Cognitive Screen Does Not Identify Cognitive Sub-Domains: Exploration of the Subscale Structure of the Perceived Deficits Questionnaire in a Systemic Lupus Erythematosus Cohort
Lisa Engel¹, Jiandong Su¹, Emily Nalder², Yael Goverover³, Monique Gignac⁴, Carmela Tartaglia⁵, Nicole Anderson¹ and Zahi Touma¹, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, ON, Canada, ³Department of Occupational Therapy, New York University, New York, NY, ⁴Instititue for Work and Health, Toronto, ON, Canada, ⁵University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada
Background/Purpose: Identifying patients with Systemic Lupus Erythematosus related cognitive impairment (SLE-CI) is critical as SLE-CI can negatively affect employment, quality of life, and disease self-management.…
Abstract Number: 2857 • 2018 ACR/ARHP Annual Meeting
An Electronic Audit, Reporting, and Data Correction System Improves the Quantity and Quality of Observational Data Collected for US Veterans Enrolled in the Veterans Affairs Rheumatoid Arthritis Registry
Grant W. Cannon^1,2, Jorge Rogas², Neill Bell³, Joshua Baker⁴, Gail S. Kerr⁵, Angelo Gaffo⁶, J. Steuart Richards⁷, Jennifer Barton⁸, Pascale Schwab⁸, Ted R. Mikuls⁹, Namrata Singh¹⁰, Liron Caplan¹¹, Deana Lazaro¹², Andreas Reimold¹³ and Brian Sauer², ¹Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ²Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ³Salt Lake City VA Medical Center and University of Utah, Dallas VA Medical Center, Dallas, TX, ⁴Philadelphia VA Medical Center and University of Pennsylvania, Philadelphia, PA, ⁵Washington VA Medical Center, Georgetown and Howard Universities, Washington, DC, ⁶Birmingham VA and University of Alabama at Birmingham, Birmingham, AL, ⁷Pittsburgh VA Medical Center and University of Pittsburgh, Pittsburgh, PA, ⁸VA Portland Health Care System and Oregon Health and Science, Portland, OR, ⁹VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, ¹⁰Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, ¹¹Div of Rheumatology, Denver VA Medical Center and University of Colorado, Aurora, CO, ¹²Brooklyn VA Medical Center and SUNY Downstate, Brooklyn, NY, ¹³Rheumatology, Dallas VA Medical Center and University of Texas - Southwestern, Dallas, TX
Background/Purpose: The Veterans Affairs (VA) Rheumatoid Arthritis (RA) (VARA) registry is an observational cohort study of US Veterans with RA at 11 VA Medical…
Abstract Number: 1261 • 2018 ACR/ARHP Annual Meeting
Development a Core Domain Set to Assess Shared Decision Making Interventions in Rheumatology: An OMERACT White Paper to Facilitate Endorsement
Karine Toupin-April¹, Jennifer Barton^2,3, Liana Fraenkel⁴, Alexa Meara⁵, Linda Li⁶, Peter Brooks⁷, Maarten de Wit⁸, Dawn Stacey^9,10, France Légaré¹¹, Beverly Shea^9,12,13, Anne Lyddiatt¹⁴, Catherine Hofstetter¹⁵, Robin Christensen¹⁶, Marieke Scholte-Voshaar^17,18, Maria Suarez-Almazor¹⁹, Annelies Boonen²⁰, Tanya Meade^21,22, Lyn March²², Janet Elizabeth Jull⁹, Willemina Campbell²³, Rieke Alten²⁴, Suvi Karuranga²⁵, Esi Morgan²⁶, Jessica Kaufmann²⁷, Sophie Hill²⁷, Lara J. Maxwell^9,10, Dorcas Beaton²⁸, Yasser El-Miedany²⁹, Shikha Mittoo³⁰, Susan J. Bartlett³¹, Jasvinder A. Singh³² and Peter Tugwell³³, ¹Children’s Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada, ²VA Portland Health Care System, Portland, OR, ³Oregon Health & Science University, Portland, OR, ⁴Yale University School of Medicine, New Haven, CT, ⁵Internal Medicine/Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁶Arthritis Research Canada, Richmond, BC, Canada, ⁷The University of Melbourne, Victoria, Australia, ⁸EULAR standing committee of PARE, Zurich, Switzerland, ⁹University of Ottawa, Ottawa, ON, Canada, ¹⁰The Ottawa Hospital Research Institute, Ottawa, ON, Canada, ¹¹Université Laval, Montreal, QC, Canada, ¹²Bruyere Research Institute, Ottawa, ON, Canada, ¹³School of Epidemiology, Public Health, and Preventive Medicine, Faculty of Medicine, University of Ottawa, and Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa, ON, Canada, ¹⁴Musculoskeletal Group, Cochrane Collaboration, Hamilton, ON, Canada, ¹⁵OMERACT patient research partner group, Ottawa, ON, Canada, ¹⁶Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, ¹⁷University of Twente, Enschede, ON, Netherlands, ¹⁸OMERACT patient research partner group, Enschede, Netherlands, ¹⁹Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, ²⁰Department of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands, Maastricht, Netherlands, ²¹Western Sydney University, New South Wales, Australia, ²²University of Sydney, New South Wales, Australia, ²³OMERACT patient research partner group, Toronto, ON, Canada, ²⁴University Medicine Berlin, Berlin, Germany, ²⁵Access to Medicine Foundation, Haarlem, Netherlands, ²⁶University of Cincinnati, Cincinnati, OH, ²⁷La Trobe University, Victoria, Australia, ²⁸Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada, ²⁹Ain Shams University, Cairo, Egypt, ³⁰Involved medicine, Toronto, ON, Canada, ³¹Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³²Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³³Center For Global Health, Institute of Population Hlth, Ottawa, ON, Canada
Background/Purpose: Shared decision making (SDM) improves decisional outcomes and patient-physician communication and holds great potential for improving the management of various rheumatology conditions. However, the…
Abstract Number: 2871 • 2018 ACR/ARHP Annual Meeting
Comprehensive Provider Judgement Is a Significant Determinant of Major Therapeutic Change in Patients with Moderate to Severe Rheumatoid Arthritis
Jacob R. Stever¹, Brian C. Sauer¹ and Grant W. Cannon², ¹Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ²Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT
Background/Purpose: We have previously reported an evaluation of 941 US Veterans in the Veterans Affairs (VA) Rheumatoid Arthritis (RA) (VARA) registry that 559 (59%)…
Abstract Number: 1446 • 2018 ACR/ARHP Annual Meeting
The Optimal Joint Set for Ultrasound Assessment of Synovitis in RA: Results from the Rasch Measurement Model
Elizabeth M.A. Hensor^1,2, Alan Tennant³, Philip G. Conaghan^1,2, Hilde B Hammer⁴, Richard J. Wakefield^1,2 and Maria Antonietta D'Agostino^1,5, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²NIHR Leeds Biomedical Research Centre, Chapel Allerton Hospital, Leeds, United Kingdom, ³Swiss Paraplegic Research, Nottwil, Switzerland, ⁴Rheumatology, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁵Rheumatology, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital, Boulogne-Billancourt, France
Background/Purpose: The recently introduced composite OMERACT-EULAR power Doppler (PD)/grey scale (GS) ultrasound (PDUS) scoring system for RA with a proposed 18 joint set was developed…
Abstract Number: 2906 • 2018 ACR/ARHP Annual Meeting
Synovitis Focused Ultrasound in Rheumatoid Arthritis: A Joint Reduction Strategy
Daniel Kuo¹, Gurjit Kaeley², Ami Ben-Artzi³, Jenny Brook⁴, Astrid Floegel-Shetty⁴, David Elashoff⁴ and Veena K. Ranganath¹, ¹Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²Rheumatology, University of Florida College of Medicine, Jacksonville, Jacksonville, FL, ³Rheumatology, Cedars Sinai Medical Center, Beverly Hills, CA, ⁴Department of Medicine Statistics Core, UCLA David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Musculoskeletal ultrasound is increasingly being used as a tool to assess inflammatory burden in rheumatoid arthritis (RA). Ultrasound-based outcome measures include power Doppler (PD)…
Abstract Number: 1455 • 2018 ACR/ARHP Annual Meeting
Development of a Predictive Model of Radiological Damage in Patients with Rheumatoid Arthritis Based on Artificial Intelligence
Jose M Lezcano¹, José Ivorra-Cortes², Alfredo Madrid³, Raquel Lopez-Mejías⁴, Javier Martin⁵, Benjamín Fernández-Gutiérrez⁶, Miguel Angel González-Gay⁷, Alejandro Balsa⁸, Isidoro Gonzalez-Alvaro⁹, Fernando Salazar¹⁰, Lydia A Alcazar¹¹ and Luis Rodriguez-Rodriguez¹¹, ¹Helix BioS CEO, Madrid, Spain, ²Rheumatology, University Hospital la Fe, Valencia, Spain, ³Rheumatology Department, and Instituto de Investigación Sanitaria (IdISSC), Hospital Clínico San Carlos, Madrid, Spain, ⁴Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, Santander, Spain, ⁵Instituto de Parasitología y Biomedicina López Neyra, Granada, Spain, ⁶Department of Rheumatology, Hospital Clinico San Carlos, Madrid, Spain, ⁷School of Medicine, University of Cantabria, Santander, Spain, Santander, Spain, ⁸Rheumatology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain, ⁹Rheumatology Department, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain, ¹⁰International Centre for Numerical Methods in Engineering (CIMNE), Madrid, Spain, ¹¹Rheumatology Department and Heath Research Institute (IdISSC), Hospital Clinico San Carlos, Madrid, Spain
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased mortality and disability. Although different factors have been associated with prognosis, it is…
Abstract Number: 2911 • 2018 ACR/ARHP Annual Meeting
Patient-Reported Outcomes Measurement Information System (PROMIS®) Global Health Short Form Is Responsive to Patient Reported Changes in SLE Health Status
Shanthini Kasturi¹, Jackie Szymonifka², Jessica R. Berman³, Kyriakos A. Kirou³, Alana B. Levine³, Lisa R Sammaritano⁴ and Lisa A. Mandl⁴, ¹Medicine/Rheumatology, Tufts Medical Center, Boston, MA, ²Hospital for Special Surgery, New York, NY, ³Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁴Hospital for Special Surgery/Weill Cornell Medicine, New York, NY
Background/Purpose: The accurate and efficient serial measurement of patient centered outcomes is a priority in the clinical care of SLE. Patient-Reported Outcomes Measurement Information Systems…
Abstract Number: 1512 • 2018 ACR/ARHP Annual Meeting
Reduction in Power Doppler Ultrasound Score with Tocilizumab Treatment Associates with Improvement in the Protective Profile of HDL in Patients with Rheumatoid Arthritis
Christina Charles-Schoeman¹, Gurjit Kaeley², Jennifer Wang³, Ani Shahbazian³, Jenny Brook⁴, David Elashoff⁴ and Veena K. Ranganath⁵, ¹Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²UF Health Jacksonville, Jacksonville, FL, ³University of California, Los Angeles, Los Angeles, CA, ⁴Department of Medicine Statistics Core, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁵1000 VETERAN BLVD., RM 32-59, UCLA, Los Angeles, CA
Background/Purpose: Musculoskeletal ultrasound (MSUS) can detect synovitis by Power doppler (PDUS) and can predict erosive progression on xrays in rheumatoid arthritis (RA) patients. We previously…
Abstract Number: 2924 • 2018 ACR/ARHP Annual Meeting
Spinal Radiographic Progression in Early Axial Spondyloarthritis: 5-Year Data from the DESIR Cohort
Sofia Ramiro¹, Désirée van der Heijde², Alexandre Sepriano³, Miranda van Lunteren⁴, Anna Molto⁵, Maria Antonietta D'Agostino⁶, Damien Loeuille⁷, Maxime Dougados⁸, M. Reijnierse⁹ and Pascal Claudepierre¹⁰, ¹Zuyderland Medical Center, Heerlen & Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Centre, Leiden, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ⁶Department of Rheumatology, Assistance publique-Hôpitaux de Paris Ambroise Paré Hospital, Boulogne-Billancourt , Université Versailles Saint Quentin en Yvelines, Paris, France, ⁷Rheumatology, University Hospital of Nancy, NANCY, France, ⁸Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁹Radiology, Leiden University Medical Center, Leiden, Netherlands, ¹⁰Hôpital Henri Mondor, Créteil, France
Background/Purpose: Spinal radiographic progression has been investigated in patients with r-axSpA, but not yet as thoroughly in early axSpA. We aimed to analyse the progression…
Abstract Number: 1591 • 2018 ACR/ARHP Annual Meeting
Is Enthesitis a Marker of Disease Severity in Early Psoriatic Arthritis?
Lihi Eder¹, Chandra Farrer² and Dana Jerome³, ¹Women's College Research Institute, University of Toronto, Women's College Hospital, Toronto, ON, Canada, ²Rheumatology, Women's College Hospital, Toronto, ON, Canada, ³University of Toronto, Women's College Hospital, Toronto, ON, Canada
Background/Purpose: Enthesitis is a key feature in psoriatic arthritis (PsA) affecting approximately a third of the patients. Ultrasound improves the detection of enthesitis compared to…

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