Abstracts tagged "Muscle Function"

Abstract Number: 0560 • ACR Convergence 2024
Association Between a Self-Report Screening Tool for Sarcopenia (SARC-F) and Disease Activity, Muscle Strength and Muscle Power Measures, Patient-Reported Outcomes and Body Composition in Patients with Spondyloarthritides
Iuliia Kononenko¹, Marius Bedei², Bjoern Buehring³, Xenofon Baraliakos⁴ and Uta Kiltz⁵, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Bochum, Germany, ²Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Herne, Germany, ³Bergisches Rheuma-Zentrum, Wuppertal, Germany, ⁴Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁵Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany
Background/Purpose: The SARC-F is a self-report screening tool for sarcopenia (Sar) used to identify individuals at risk for poor functional outcomes [1]. The aim of this study was…
Abstract Number: 0684 • ACR Convergence 2024
The Diagnostic Accuracy of Ultrasound for Low Muscle Mass in Women with Systemic Sclerosis
Lucas Dória¹, Vanessa Hax², André Mallmann², Rafaela Santo³, Leonardo Santos², Stephanie Pilotti², Daniel Moraes², Isabella Boening², Pedro Glanze², ODIRLEI MONTICIELO¹, Ricardo Xavier⁴ and Rafael Chakr⁵, ¹Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, ²Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, ³Health Research and Innovation Science Centre, Klaipeda University, Klaipeda, Lithuania, Porto Alegre, Rio Grande do Sul, Brazil, ⁴Universidade Federal do Rio Grande do Sul, Porto Alegre/RS, Rio Grande do Sul, Brazil, ⁵Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Background/Purpose: Patients with systemic sclerosis (SSc) often experience body composition changes, including low muscle mass (myopenia), associated with physical disability, hospitalization and death. Our purpose…
Abstract Number: 1079 • ACR Convergence 2024
Early Recognition of Myositis: Time Correlation Between Transaminases and Inflammatory Myopathy in a Community-Based Rheumatology Practice
Anjali nidhaan, Shannon Iriza, Abbie West, Michael martin and Gauri Pethe, prisma health, columbia, SC
Background/Purpose: Recognizing muscle breakdown as a potential cause of elevated transaminases is crucial in the primary care setting to facilitate early referral to rheumatology for…
Abstract Number: 1182 • ACR Convergence 2024
Assessing Male Pelvic Floor Contractions Using a Novel External Pressure Device and Ultrasound
Benedetto Giardulli¹, Mirko Job¹, Filippo Recenti¹, Gaia Leuzzi¹, Alessandro Muda², Ottavia Buccarella¹ and Marco Testa¹, ¹University of Genova, Savona, Italy, ²Lavagna Hospital - Radiology Dept., Genova, Italy
Background/Purpose: Men with rheumatic and musculoskeletal diseases (RMD) often experience sexual dysfunctions such as pelvic floor pain and erectile dysfunctions, which affect their sexual well-being.…
Abstract Number: 2061 • ACR Convergence 2024
Associations Between Intramyocellular Lipid and Muscle Function in Patients with Osteoarthritis
Rachel Gillcrist¹, Marianna Olave², Ryan Armbruster³ and Joshua Baker⁴, ¹Corporal Michael J. Crescenz VA Medical Center, Philadelphia, ²Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, ⁴Department of Medicine, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA
Background/Purpose: Intramyocellular lipids (IMCL), stored within lipid droplets in skeletal muscle cells, serve as an important metabolic fuel source during exercise. Endurance athletes have demonstrated higher…
Abstract Number: 2670 • ACR Convergence 2024
Sera from Patients with Idiopathic Inflammatory Myopathy Induces Muscle Weakness, Mitochondrial Dysfunction and Induction of Cytokines in Isolated Skeletal Muscle
Cecilia Leijding¹, Suchada Kaewin², Kristofer Andreasson¹, Tomas Schiffer¹, Angeles Galindo-Feria³, Begum Horuluoglu¹, Mattias Carlstrom¹, Stefano Gastaldello¹, Helene Alexanderson⁴, Ingrid Lundberg⁵ and Daniel Andersson⁶, ¹Karolinska Institutet, Stockholm, Sweden, ²Karolinska Institutet, Stockholm, ³Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, ⁴Karolinska University Hospital, Stockholm, Sweden, ⁵Karolinska Universitetssjukhuset, Karolinska Institutet, Stockholm, Sweden, ⁶Karolinska Institutet, Solna, Sweden
Background/Purpose: Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune inflammatory muscle disorders characterized by symmetrical skeletal muscle weakness and accelerated fatigue. Although signs…
Abstract Number: 1971 • ACR Convergence 2023
Muscle Pathology in Patients with Primary Biliary Cholangitis
Jose Cesar Milisenda¹, Iago Pinal-Fernandez², Katherine Pak², Maria Casal-Dominguez³, Yaiza Duque-Jaimez⁴, Gloria Garrabou¹, Sandra Muñoz-Braceras⁵, Mariona Guitart-Manpel¹, Jose Jiram Torres-Ruiz⁵, Ester Tobias⁴, Maria Dolores Cano⁴, Iban Aldecoa⁴, Josep Maria Grau¹ and Andrew Mammen³, ¹Muscle Research Unit, Internal Medicine Service, Hospital Clinic, Barcelona, Spain, ²National Institutes of Health, Bethesda, MD, ³NIH, Bethesda, MD, ⁴Hospital Clínic de Barcelona, Barcelona, Spain, ⁵Muscle Disease Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD
Background/Purpose: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease that primarily affects middle-aged women. It is characterized by elevated serum alkaline phosphatase levels,…
Abstract Number: 2467 • ACR Convergence 2023
Quadriceps Muscle Fat Composition but Not Muscle Energetics Is Associated with Knee Osteoarthritis: Initial Results from the Study of Muscle, Mobility, and Aging
Giovanna Distefano¹, Daniel Evans², Peggy Cawthon², John Lynch², Thomas Link², Philip Kramer³, Stephanie Harrison², Bret Goodpaster⁴, Jane Cauley⁵, Theresa Mau², Paul Coen⁴, Lauren Sparks⁴ and Nancy Lane⁶, ¹AventisHealth, Orlando, FL, ²University of California San Francisco, San Francisco, CA, ³Wake Forest, Winston-Salem, NC, ⁴Aventis Health, Orlando, FL, ⁵University of Pittsburgh, Pittsburgh, PA, ⁶University of California, Hillsborough, CA
Background/Purpose: Osteoarthritis (OA) remains the most common cause of joint pain and disability with age, and to date, effective treatments to reduce pain and slow…
Abstract Number: 0302 • ACR Convergence 2023
Remission in Anti-HMGCR Positive Immune-mediated Necrotizing Myopathy Without the Use of Glucocorticoids: A Multicentric Study of 24 Patients
David Martinez-Lopez¹, Cristina Corrales Selaya², Diana Prieto-Peña², Piotr Szczesny³, Antonella Notarnicola⁴, Ricardo Blanco⁵, Ingrid Lundberg⁶ and Maryam Dastmalchi⁶, ¹Hospital de Sierrallana, Santander, Spain, ²Hospital Universitario Marqués de Valdecilla, Santander, Spain, ³Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Department of Neurology, Medical University of Warsaw, Warsaw, Poland, ⁴Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁵Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ⁶Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden
Background/Purpose: Statin-induced immune mediated necrotizing myopathy (IMNM) is a subtype of inflammatory myopathy associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) autoantibodies. This condition is characterized by progressive…
Abstract Number: 1147 • ACR Convergence 2023
Blood-Based Biomarkers of Inflammation and Tissue Remodeling Can Discriminate Between Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis and Are Associated with Hand Function
Helena Port I Linares¹, Birte Coppers², Sara Bayat², Godonou Elie-Tino², Larissa Valor-Mendez², David Simon², Filippo Fagni², Giulia Corte², Anne-Christine Bay-Jensen³, Koray Tascilar², Axel Hueber⁴, Verena Schoenau², Michael Sticherling⁵, Simon Heinrich⁶, Daniela Bohr², Georg Schett⁷, Arnd Kleyer⁸, Sigrid Leyendecker⁶, Signe Holm Nielsen³ and Anna-Maria Liphardt⁹, ¹Nordic Bioscience A/S / University of Copenhagen, Copenhagen, Denmark, ²Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology / Deutsches Zentrum Immuntherapie, Erlangen, Germany, ³Nordic Bioscience, Herlev, Denmark, ⁴Division of Rheumatology, Klinikum Nürnberg, Paracelsus Medical University / Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology, Nürnberg, Germany, ⁵Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Dermatology, Erlangen, Germany, ⁶Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Institute of Applied Dynamics, Erlangen, Germany, ⁷Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, ⁸University Hospital Erlangen, Erlangen, Germany, ⁹Friedrich-Alexander-University Erlangen-Nuremberg, Internal Medicine 3 - Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany
Background/Purpose: Inflammatory musculoskeletal diseases including rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are characterized by physical function impairment due to progressive inflammatory and structural changes.…
Abstract Number: 1177 • ACR Convergence 2023
Anti-HMGCR Autoantibody Levels in the Follow-up of Statin-induced Immune-mediated Necrotizing Myopathy: Multicentric Study of 24 Patients
David Martinez-Lopez¹, Cristina Corrales Selaya², Diana Prieto-Peña², Piotr Szczesny³, Antonella Notarnicola⁴, Marcos Lopez-Hoyos⁵, Ricardo Blanco⁶, Ingrid Lundberg⁷ and Maryam Dastmalchi⁷, ¹Hospital de Sierrallana, Santander, Spain, ²Hospital Universitario Marqués de Valdecilla, Santander, Spain, ³Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Department of Neurology, Medical University of Warsaw, Warsaw, Poland, ⁴Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁵Marques de Valdecilla University Hospital-IDIVAL, Santander, Spain, ⁶Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ⁷Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden
Background/Purpose: Statin-induced immune-mediated necrotizing myopathy (IMNM) is associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) autoantibodies. It is characterized by elevated creatine kinase (CK) levels, and severe muscle…
Abstract Number: 1789 • ACR Convergence 2023
Microtrauma Exacerbates Arthritis and Enthesitis in Curdlan-administered SKG Mice by Inducing FGF16 Expresssion
Seung Hoon Lee¹, Chanhyeok Jeon¹, Sungsin Jo¹ and Tae-Hwan Kim², ¹Hanyang University Institute for Rheumatology Research, Seoul, South Korea, ²Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Microtrauma might be considered a crucial of various environmental factors in AS, but there is still unknown whether microtrauma has a direct/indirect role in…
Abstract Number: 1957 • ACR Convergence 2023
Non-Linear Mendelian Randomization Analyses Support a Role for Low Vitamin D Status in Sarcopenia Risk
Tingting Sha¹, Yilun Wang², Yuqing Zhang³, Nancy Lane⁴, Changjun Li⁵, Jie Wei⁶, Chao Zeng² and Guanghua Lei², ¹Hunan Key Laboratory of Joint Degeneration and Injury, Changsha, China, ²Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China, ³Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, ⁴University of California, Hillsborough, CA, ⁵National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China, ⁶Health Management Center, Xiangya Hospital Central South University, Changsha, China
Background/Purpose: Vitamin D deficiency is commonly associated with sarcopenia; however, the latest International Clinical Practice Guidelines for Sarcopenia do not recommend vitamin D supplementation for…
Abstract Number: 1233 • ACR Convergence 2022
Ultrasound Is Reliable in the Assessment of Muscle Echogenicity in Patients with Rheumatic Diseases: Results of a Multicenter International Web-based Study
Andrea Di Matteo¹, Erica Moscioni², Maria Giovanna Lommano¹, Edoardo Cipolletta¹, Gianluca Smerilli¹, Sonia Farah¹, Carla Airoldi³, Sibel Aydin⁴, Becciolini Andrea⁵, Karina Bonfiglioli⁶, Marina Carotti⁷, Greta Carrara⁸, Tomas Cazenave⁹, Davide Corradini¹⁰, Micaela Ana Cosatti¹¹, Juan Josè de Agustin¹², Giulia Maria Destro Castaniti¹³, Marco Di Carlo¹, Eleonora Di Donato⁵, Luca Di geso¹⁴, Ashley Elliott¹⁵, Daniela Fodor¹⁶, Francesca Francioso¹, Alessandra Gabba¹⁷, Cristina Hernández-Díaz¹⁸, Rudolf Horvath¹⁹, Jana Hurnakova¹⁹, Diogo Jesus²⁰, Josefina Marin²¹, Maria Victoria Martire²², Riccardo Mashadi-Mirza²³, Marco Massarotti²⁴, Alice Andreea Musca²⁵, Jagdish Nair²⁶, Tadashi Okano²⁷, Ioannis Papalopoulos²⁸, Javier Eduardo Rosa²¹, Marcos Rosemffet²⁹, João Rovisco³⁰, Davide Rozza⁸, Fausto Salaffi¹, Crescenzio Scioscia³¹, Carlo Alberto Scirè⁸, Maria-Magdalena Tamas³², Shun Tanimura³³, Lucio Ventura-Rios¹⁸, Catalina Villota-Eraso³⁴, Orlando Villota³⁵, Paraksevi V Voulgari³⁶, Florentin Ananu Vreju³⁷, Gentiana Vukatana³⁷, Johana Zacariaz Hereter²¹, Anna Zanetti⁸, Walter Grassi¹ and Emilio Filippucci¹, ¹Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Jesi, Italy, ²Polytechnic University of Marche, Jesi, Italy, ³Hospital Provincial, Rosario, Argentina, ⁴University of Ottawa, Rheumatology, Ottawa, Canada, Ottawa, ON, Canada, ⁵Department of Medicine, Internal Medicine and Rheumatology Unit, Azienda Ospedaliero Universitaria di Parma, Parma, Italy, ⁶Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁷Department of Radiology, Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy, ⁸Epidemiology Unit, Italian Society of Rheumatology, Milano, Italy, ⁹Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ¹⁰Rheumatology Unit, University Clinic AOU Cagliari, Cagliari, Italy, ¹¹CEMIC, Centro de educación médica e investigaciones médicas "Norberto Quirno", Buenos Aires, Argentina, ¹²Vall D'hebron University Hospital, Barcelona, Spain, ¹³Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Rheumatology section, University of Palermo, Palermo, Italy, ¹⁴Ospedale Madonna del Soccorso, Department of Internal Medicine, San Benedetto del Tronto, Italy, ¹⁵Centre for Experimental Medicine, Queen's University, Belfast, Northern Ireland, United Kingdom, ¹⁶2nd Internal Medicine Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania, ¹⁷Local Health Unit (ASL), Oristano, Italy, ¹⁸Division de Reumatologia. Instituto Nacional de Rehabilitacion "Luis Guillermo Ibarra Ibarra", Ciudad de México, Mexico, ¹⁹Department of Paediatric and Adult Rheumatology, University Hospital Motol, Prague, Czech Republic, ²⁰Rheumatology Department, Centro Hospitalar de Leiria, Leira, Portugal, ²¹Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²²San Roque Hospital, La Plata, Buenos Aires, Argentina, ²³Radiology Department, A.O. Ospedali Riuniti Marche Nord, Pesaro, Italy, ²⁴Department of Rheumatology, University Hospitals Dorset NHS Foundation Trust, Christchurch Hospital, Christchurch, United Kingdom, ²⁵Department of Rheumatology - Colentina Clinical Hospital, Bucharest, Romania, ²⁶Rheumatology, Liverpool University Hospitals Foundation Trust, Liverpool, United Kingdom, ²⁷Department of Orthopedic Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan, ²⁸Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Heraklion, Heraklion, Greece, ²⁹Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, ³⁰Rheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ³¹Department of Emergency and Organ Transplantations-Rheumatology Unit, University of Bari "Aldo Moro", Bari, Italy, ³²Department of Rheumatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania, ³³Rheumatology Department, Hokkaido Medical Center for Rheumatic Diseases, Sapporo, Japan, ³⁴IPS Servicio integral de reumatología e inmunología Dr Orlando Villota, Pasto, Colombia, ³⁵Division of Rheumatology, Fundación Hospital San Pedro, Pasto, Colombia, ³⁶Department of Rheumatology, School of Health Science, Faculty of Medicine, University of Ioannina, Ioannina, Greece, ³⁷Rheumatology Department, University of Medicine and Pharmacy of Craiova, Craiova, Romania, ³⁷Rheumatology Unit; IRCCS Policlinico S. Orsola Malpighi, Bologna, Italy
Background/Purpose: Studies have showed that an increased ultrasound (US) muscle echogenicity indicating fatty replacement/fibrosis of muscle tissue may represent an early indicator of muscle involvement associated…
Abstract Number: 1886 • ACR Convergence 2022
Statin-induced Immune-mediated Miopathy: Treatment with Glucocorticoid-free Protocols and Role of Muscle Biopsy in the Follow-up
David Martínez-López¹, Piotr Szczęsny², Inger Nennesmo³, Karina Gheorghe⁴, Antonella Notarnicola⁵, Helene Alexanderson⁶, Ingrid Lundberg⁷ and Maryam Dastmalchi⁸, ¹Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland. Department of Neurology, Medical University of Warsaw, Warsaw, Poland, ³Department of Pathology, Karolinska University Hospital,Pathology, Karolinska University Hospital., Stockholm, Sweden, ⁴Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet. Rheumatology, Karolinska University Hospital Stockholm, Sweden. Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, ⁵Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, ⁶Karolinska Institutet, Stockholm, Sweden, ⁷Karolinska Universitetssjukhuset, Karolinska Institutet, Stockholm, Sweden, ⁸Karolinska University Hospital, Stockholm, Sweden
Background/Purpose: Statin-induced immune mediated necrotizing myopathy (IMNM) is a recently identified autoimmune condition associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies, characterized by progressive muscle weakness leading…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].