Abstracts Archive - Page 980 of 2607 - ACR Meeting Abstracts

Abstract Number: 090 • 2020 Pediatric Rheumatology Symposium
Using a Patient-Engaged Approach to Identify Cross-Cutting Disease Factors Impacting Mental Health in Youth with Rheumatologic Disease
Ashley Danguecan¹, Oluwatunmise Fawole ², Michelle Reed ³, Julia Harris ⁴, Aimee Hersh ⁵, Martha Rodriquez ⁶, Karen Onel ⁷, Erica Lawson ⁸, Tamar Rubinstein ⁹, Kaveh Ardalan ¹⁰, Esi Morgan ¹¹, Anne Paul ¹², Judy Barlin ¹³, R. Paola Daly ¹⁴, Mitali Dave ¹⁵, Shannon Malloy ¹⁶, Shari Hume ¹⁷, Suzanne Schrandt ¹⁸, Laura Marrow ¹⁹, Angela Chapson ²⁰, Donna Napoli ³, Michael Napoli ³, Miranda Moyer ³, Vincent Del Gaizo ²¹, Emily von Scheven ²² and Andrea Knight ²³, ¹Hospital for Sick Children, Toronto, Canada, ²New York University School of Medicine, New York, ³The Children's Hospital of Philadelphia, Philadelphia, ⁴Children's Mercy Kansas City, Overland Park, ⁵University of Utah Primary Children's Hospital, Salt Lake City, ⁶Riley Hospital For Children At Indiana University, Carmel, ⁷Hospital for Special Surgery, New York, ⁸UCSF, San Francisco, ⁹Albert Einstein College of Medicine, White Plains, ¹⁰Duke University Medical Center, Durham, ¹¹Cincinnati Children's Hospital, Cincinnati, ¹²Cincinnati Children's Hospital Medical Centre, Cincinnati, ¹³Lupus Foundation of America, Miami, ¹⁴Lupus Foundation of America, Washington, ¹⁵Short Hills, ¹⁶Cure JM Foundation, Leesburg, ¹⁷Encinitas, ¹⁸Arthritis Foundation, Atlanta, ¹⁹Arthritis Foundation, Saint Paul, ²⁰Children's Hospital of Philadelphia, Philadelphia, ²¹Childhood Arthritis & Rheumatology Research Alliance (CARRA), Whitehouse Station, ²²San Francisco, ²³SickKids Research Institute, Toronto, Canada
Background/Purpose: Mental health problems are common and often untreated in youth with rheumatologic disease, yet their relationship with disease features is poorly understood. We engaged…
Abstract Number: 091 • 2020 Pediatric Rheumatology Symposium
Protracted Febrile Myalgia Findings on Magnetic Resonance Imaging
Neta Hana Aviran¹, Liora Harel ², Gil Amarilyo ³, Yosef Uziel ⁴, Yonatan Butbul Aviel ⁵ and Rotem Tal ⁶, ¹Schneider children's medical center of Israel, Kfar Saba, Israel, ²Schneider Hospital, Tel Aviv University, Petah-Tiqva, Israel, ³Schneider Hospital, Tel Aviv University, Kibbutz Magal, Israel, ⁴Kfar Saba, Israel, ⁵Rambam Medical center, Haifa, Hefa, Israel, ⁶schneider medical center, Ramat Gan, Israel
Background/Purpose: Protracted febrile myalgia syndrome (PFMS) is a rare complication of familial Mediterranean fever (FMF) which consist of prolonged attack of fever, excruciating myalgia (up…
Abstract Number: 092 • 2020 Pediatric Rheumatology Symposium
The Initial Treatment of Systemic Juvenile Idiopathic Arthritis: An International Collaboration Among 10 Registries
Mary Beth Son¹, Yukiko Kimura ², Kristiina Aalto ³, Lillemor Berntson ⁴, Johnathan Dallas ¹, Ciaran Duffy ⁵, Mia Glerup ⁶, Jaime Guzman ⁷, Troels Herlin ⁸, Petteri Hovi ⁹, Kimme Hyrich ¹⁰, Jens Klotsche ¹¹, Bo Magnusson ¹², Vanessa McIntyre ¹³, Ellen Nordal ¹⁴, Seza Ozen ¹⁵, Maria Jose Santos ¹⁶, Betul Sozeri ¹⁷ and Timothy Beukelman ¹⁸, ¹Boston Children's Hospital, Boston, Massachusetts, ²Hackensack Meridian School of Medicine, Hackensack, ³Department of Pediatrics, New Children's Hospital, Helsinki University Hospital, Pediatric Research Center, University of Helsinki, Helsinki, Finland., HUS, Finland, ⁴Department of Womens and Childrens Health, Uppsala University, Uppsala, Sweden., Uppsala, Sweden, ⁵Ottawa, Canada, ⁶Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, ⁷University of British Columbia and BC Children's Hospital, Vancouver, Canada, ⁸Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark., Aarhus N, Denmark, ⁹Helsinki University Hospital, Helsinki, Finland, ¹⁰Manchester, United Kingdom, ¹¹Berlin, Germany, ¹²Karolinska University Hospital, Stockholm, Sweden, ¹³Manchester University, Manchester UK, United Kingdom, ¹⁴Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway., Tromsø, Norway, ¹⁵Hacettepe University, Division of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, ¹⁶Portugal, ¹⁷Boston, Turkey, ¹⁸University of Alabama at Birmingham, Birmingham
Background/Purpose: The introduction of biologic medications has revolutionized the care of children with systemic juvenile idiopathic arthritis (SJIA). Differences in treatment approaches among different countries…
Abstract Number: 093 • 2020 Pediatric Rheumatology Symposium
Treatment of Systemic Juvenile Idiopathic Arthritis in the CARRA Registry
Ginger Janow ¹, Timothy Beukelman ², Yukiko Kimura ³, Rayfel Schneider ⁴, Shalini Mohan ⁵, Gail Rodich ⁶ and Mary Beth Son⁷ for the CARRA investigators, ¹Joseph M. Sanzari Children's Hospital at Hackensack Meridian Health, Hackensack, New Jersey, ²University of Alabama at Birmingham, Birmingham, ³Hackensack Meridian School of Medicine, Hackensack, ⁴The Hospital for Sick Children, Toronto, Canada, ⁵Genentech, Inc., South San Francisco, ⁶Genentech, Mill Valley, ⁷Boston Children's Hospital, Boston, Massachusetts
Background/Purpose: The treatment of systemic juvenile idiopathic arthritis (SJIA) has changed dramatically over the past decade, associated with overall improvement in functional outcomes. There may…
Abstract Number: 094 • 2020 Pediatric Rheumatology Symposium
A Good Inter- and Intra-observer Reliability of Subtypes in Nailfold Capillary Micro-haemorrhages in Childhood-onset Systemic Lupus Erythematosus
Sandy Bergkamp¹, Dieneke Schonenberg-Meinema ², Merlijn van den Berg ², Vanessa Smith ³, Amber Vanhaecke ⁴, Karin Melsens ⁴, Amara Nassar Sheikh Rashid ⁵, Taco Kuijpers ⁶ and Maartje Boumans ⁷, ¹Amsterdam Medical Center, Uithoorn, Netherlands, ²Amsterdam, Netherlands, ³Ghent University Hospital, Ghent, Belgium, ⁴Ghent University, Ghent, Belgium, ⁵Amsterdam Medical Center, Amsterdam, Netherlands, ⁶AMC, Amsterdam, Netherlands, ⁷Maxima Medical Center, Eindhoven, Netherlands
Background/Purpose: In previous studies, micro-haemorrhages have often been observed in nailfold capillaroscopy in SLE.1 The interpretation of this finding is still a topic of research.…
Abstract Number: 095 • 2020 Pediatric Rheumatology Symposium
Pyoderma Gangrenosum Ulceration as a Presenting Feature of Pediatric Granulomatosis with Polyangiitis (GPA)
Rotem Semo¹, Rotem Tal ², Tomas Dallos ³, Liora Harel ⁴, Lukas Plank ³ and Linda Wagner-Weiner ¹, ¹university of chicago, chicago, Illinois, ²schneider medical center, Ramat Gan, Israel, ³National Institute of Child Diseases, Bratislava, Slovakia, ⁴Schneider Hospital, Tel Aviv University, Petah-Tiqva, Israel
Background/Purpose: GPA is a form of anti-neutrophilic cytoplasmic antibody vasculitis affecting small to medium sized vessels and involves most commonly the kidneys and the respiratory…
Abstract Number: 096 • 2020 Pediatric Rheumatology Symposium
Medication Adherence in Adolescents and Young Adults with Childhood Onset SLE
Rotem Semo Oz¹, Linda Wagner-Weiner ², Cuoghi Edens ¹, Grace Cameron ¹ and Melissa Tesher ¹, ¹university of chicago, Chicago, ²University of Chicago, Chicago, Illinois
Background/Purpose: Compared to adults with SLE, young patients with SLE face particular challenges, including more severe disease, more renal involvement and medications side effects like…
Abstract Number: 097 • 2020 Pediatric Rheumatology Symposium
A Pilot Randomized Controlled Trial of the iCanCope Pain Self-management Application for Adolescents with Juvenile Idiopathic Arthritis
Chitra Lalloo ¹, Lauren Harris ², Amos Hundert ², Roberta Berard ³, Joseph Cafazzo ⁴, Mark Connelly ⁵, Brian Feldman ², Kristin Houghton ⁶, Adam Huber ⁷, Ronald Laxer ⁸, Nadia Luca ⁹, Heinrike Schmeling ¹⁰, Lynn Spiegel ¹¹, Lori Tucker ¹², Quynh Pham ⁴, Cleo Davies-Chalmers ¹³ and Jennifer Stinson¹⁴, ¹The Hospital for Sick Children, Toronto, Ontario, Canada, ²The Hospital for Sick Children, Toronto, Canada, ³Children's Hospital London Health Sciences Centre, London, Canada, ⁴University of Toronto, Toronto, Canada, ⁵Kansas City, ⁶University of British Columbia - Vancouver, Vancouver, Canada, ⁷IWK Health Centre & Dalhousie University, Halifax, Nova Scotia, Canada, ⁸The Hospital for Sick Children and University of Toronto, Toronto, Canada, ⁹University of Calgary, Calgary, Alberta, Canada, ¹⁰Alberta Children's Hospital/University of Calgary, Calgary, Alberta, Canada, ¹¹University of Toronto/Hospital for Sick Children, Thornhill, Canada, ¹²BC Children's Hospital, Vancouver, British Columbia, Canada, ¹³The Hospital for Sick Children, Toonto, Canada, ¹⁴University of Toronto & The Hospital for Sick Children, Toronto, Ontario, Canada
Background/Purpose: Pain is the most common symptom of Juvenile Idiopathic Arthritis (JIA), a chronic childhood illness that has potentially debilitating effects on health-related quality of…
Abstract Number: 098 • 2020 Pediatric Rheumatology Symposium
Early Treatment with Anakinra in Systemic Juvenile Idiopathic Arthritis
Manuela Pardeo¹, Claudia Bracaglia ¹, Emanuela Sacco ¹, Denise Pires Marafon ¹, Antonella Insalaco ¹, Giulia Marucci ¹, Rebecca Nicolai ², Virginia Messia ¹ and Fabrizio De Benedetti ¹, ¹Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesu', Rome, Italy, ²IRCCS Ospedale Pediatrico Bambino Gesu', Rome, Italy
Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) should be considered as a polygenic autoinflammatory disease. Interleukin 1 (IL-1) has been shown to be a major mediator…
Abstract Number: 099 • 2020 Pediatric Rheumatology Symposium
Reversible Hepatotoxicity to IL-1/IL-6 Blockade in Pediatric Patients with Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome
Omkar Phadke¹, Sampath Prahalad ² and Kelly Rouster-Stevens ³, ¹EMORY, Atlanta, Georgia, ²Emory + Children's Pediatric Institute, Atlanta, ³Emory University/Children's Healthcare of Atlanta, Atlanta, Georgia
Background/Purpose: Treatment for systemic JIA (sJIA) complicated by macrophage activation syndrome (MAS) may involve blockade of IL-1 and IL-6. There are reports of adults with…
Abstract Number: 100 • 2020 Pediatric Rheumatology Symposium
Does Anakinra Dampen Neuronal Damage in Children with Febrile-Infection Related Epilepsy Syndrome (FIRES): A Single Center Review of Neuroimaging
Eyal Muscal¹, Jill Hunter ², Yi-Chen Lai ² and James Riviello ², ¹Section of Rheumatology, Department of Pediatrics, Baylor College of Medicine, houston, ²BCM/TCH, Houston
Background/Purpose: Febrile-illness related epilepsy syndrome (FIRES), characterized by the emergence of super refractory status epilepticus (SRSE) in previously healthy children following a febrile illness, is…
Abstract Number: 101 • 2020 Pediatric Rheumatology Symposium
Uveitis Treatment in the CARRA II Registry: Tumor Necrosis Factor-inhibitors and Beyond
Mona Riskalla¹, Fatima Barbar-Smiley ², Michael Shyne ¹ and Melissa Lerman ³, ¹University of Minnesota, Minneapolis, Minnesota, ²Nationwide Children's Hospital, Columbus, Ohio, ³Philadelphia, Pennsylvania
Background/Purpose: Uveitis associated with JIA (JIA-U) is the most common extra-articular complication of JIA. As JIA-U is associated with significant risk of visual loss and…
Abstract Number: 102 • 2020 Pediatric Rheumatology Symposium
Implications of Positive Tests for ANCA in a Pediatric Population
Karen James¹, Peter Merkel ² and Aimee Hersh ³, ¹University of Utah, 84113, Utah, ²University of Pennsylvania, Philadelphia, ³University of Utah Primary Children's Hospital, Salt Lake City
Background/Purpose: Testing for ANCA, particularly performed by ELISA (anti-MPO/PR3) is highly sensitive and specific for ANCA-associated vasculitis (AAV). However ANCA testing may be used in…
Abstract Number: 103 • 2020 Pediatric Rheumatology Symposium
Unexpectedly High Incidence of Kawasaki Disease in a Well-Characterized Population in Atlantic Canada
Abdulrahman Alkanhal¹, Joseph , Saunders ², Fajer Altammar ³, Adam Huber ⁴, Andrew Lynk ², Alison MacLeod ⁵, Oliva Ortiz-Alvarez ⁶, Meighan Adams ², Suzanne Ramsey ⁷, Elizabeth Stringer ⁷, Andrew Warren ² and Bianca Lang ⁸, ¹University of Alberta, Edmonton, Alberta, Canada, ²Dalhousie University, Halifax, Canada, ³Mcmaster University, Hamilton, Canada, ⁴IWK Health Centre & Dalhousie University, Halifax, Nova Scotia, Canada, ⁵Annapolis Valley Health, Kentville, Canada, ⁶St Martha's Regional Hospital, Antigonish, Canada, ⁷IWK Health Centre, Halifax, Canada, ⁸Dalhousie University - Halifax, Halifax, Canada
Background/Purpose: Kawasaki Disease (KD), a systemic vasculitis of unknown etiology, is now the leading cause of acquired heart disease in children in North America. Its…
Abstract Number: 104 • 2020 Pediatric Rheumatology Symposium
Patients Perspectives on Living with a Systemic Autoinflammatory Disease: Impact on Quality of Life
Mariana Correia Marques¹, Nicole Tennermann ², Sivia Lapidus ³, Grant Schulert ⁴, Jennifer Tousseau ², Rashmi Sinha ⁵, Karen Durrant ⁶, Saskya Angevare ⁷ and Fatma Dedeoglu ⁸, ¹Boston Children's Hospital, Boston, Massachusetts, ², ³The Joseph M. Sanzari Children's Hospital, Hackensack Meridian Health, Maplewood, ⁴Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, ⁵Systemic JIA Foundation, Cincinnati, ⁶Autoinflammatory Alliance, San Francisco, ⁷Amersfoort, Netherlands, ⁸Boston Children's Hospital, Boston
Background/Purpose: Systemic autoinflammatory diseases (SAIDs) encompass multiple clinical entities in which spontaneous inflammation occurs due to dysregulation of the innate immune response. The variability in…

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