Date: Friday, November 6, 2020
Session Type: Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose: The Paraguayan-Uruguayan cohort of patients with rheumatic inflammatory diseases (BIOBADAGUAY), collect clinical and epidemiological information on adults and children patients receiving biological therapies (BT). The obtained data enable to describe with comparative purposes the cohort of patients, considering the age of symptom onset (i.e. juvenile or adult)
Methods: BIOBADAGUAY cohort includes 18 centers (9 in Uruguay and 9 in Paraguay). The descriptive analysis was made in two phases. First, we have selected the adult population on BT and second, we have separated it in two groups according onset of disease considering the age when diagnosis of rheumatic disease was made. Clinical features of both populations were described in a second phase
Results: A total of 766 adult patients was included, in which 91,1% had adult-onset, and 8.9% had juvenile-onset rheumatic disease. Female predominance was observed in both adult-onset and juvenile-onset groups (74.1% vs 64.7%, respectively). Mean disease duration was 18.5 ± 11.2 years for juvenile-onset rheumatic disease and 13.1 ± 8.7 years for adult-onset rheumatic disease. Disease activity was similar for both rheumatoid arthritis and spondylarthritis in the two groups. All of juvenile-onset rheumatic disease patiets, did not have a comorbidity when starting a BT. Mean body mass index was 24.9 ± 4.5 for juvenile-onset rheumatic disease and 27.9 ± 6.0 for adult-onset rheumatic disease. Table 1 describes main clinical and epidemiological characteristics of analyzed populations.
Conclusion: Patients with juvenile-onset rheumatic disease present with particular characteristics (disease duration, comorbidities and mean body mass index) that differentiate them from adult-onset rheumatic disease patients. This should be taken into consideration when assessing and follow-up is being made on each patient
To cite this abstract in AMA style:Cabrera N, Valinotti V, Avila-Pedretti G, Cabrera S, Melgarejo P, Morel Z, Roman L, Babak P, Acosta R, Glitz R, Cordovilla D, Rolon R, Zanotti-Cavazzoni M, Franco Britos M, Vazquez M, Delgadillo P, Acosta I, Martinez M, Elizaur G, Romero M, Paredes E, de Abreu P, Segovia L. Clinical Characteristics of Patients with Rheumatism of Juvenile Onset and Adult Onset in the BIOBADAGUAY Cohort [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/clinical-characteristics-of-patients-with-rheumatism-of-juvenile-onset-and-adult-onset-in-the-biobadaguay-cohort/. Accessed January 27, 2022.
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